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Congresos<\/p>\n

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\"congreso\"Takagi, T., Tanizawa, O., Sugita, N., Mori, M., Otsuki, Y., Yamaji, K., Kurachi, K., Cacabelos, R., Nishimura, T., Senba, E., Tohyama, M., Shiotani, Y. Study of immunoreactive- oxytocin in human placenta and its localization. Proc. 56th Jap. Cong. Endocrinol., Osaka, Folia Endocrinol. Jap. 59:652 (1983). <\/p>\n

Cacabelos, R. Effect of social and individual factors on the inner organization and efficiency of a multidisciplinary group. 10th World Cong. Soc. Psychiatry, Osaka, Abst.129 (1983). <\/p>\n

Cacabelos, R. Chronological changes in hypothalamic histamine and catecholamines after bilateral adrenalectomy. 5th Meet. Histamine Res., Okayama, 18 Nov. (1983). <\/p>\n

Otsuki, Y., Takagi, T., Mori, M., Sugita, N., Cacabelos, R., Yamaji, K., Tanizawa, O. Immunoreactive vasopressin in human placenta. Proc. 57th Jap. Cong. Endocrinol., Tokyo, Folia Endocrinol. Jap., 60:344 (1984), <\/p>\n

Wada, H., Watanabe, T., Yamatodani, A., Itoi, N., Cacabelos, R., Seo, M., Kiyono, S., Nagai, K., Nakagawa, H. Physiological functions of histamine in the brain. Frontiers in histamine research. An International Symposium. Paris, Abst. 44 (1984). <\/p>\n

Cacabelos, R., Yamatodani, A., Watanabe, T., Takagai, T., Tanizawa, O., Hariguchi, S., Nishimura, T., Wada, H. Neuroendocrine functions of histamine: Putative modulations on ACTH, vasopressin, and oxytocin. Frontiers in histamine research. An International Symposium. Paris, Abst. 49 (1984). <\/p>\n

Yamatodani, A., Fukuda, H., Cacabelos, R., Watanabe, T., Wada, H. A sensitive and specific method for determination of histamine in the brain by high-performance liquid chromatography-fluorometry. Frontiers in histamine research. An International Symposium. Paris, Abst. 80 (1984). <\/p>\n

Cacabelos, R., Takagi, T., Otsuki, Y., Sugita, N., Tanizawa, O., Nishimura, T. Sequential evolution of oxytocin and vasopressin in the hypothalamo-hypophyseal system after adrenalectomy. Proc. 57th Jap. Cong. Endocrinol., Kobe, Folia Endocrinol. Jap., 60:1132 (1984). <\/p>\n

Wada, H., Watanabe, T., Yamatodani, A., Cacabelos, R., Itoi, N., Seo, M., Kiyono, S., Nagai, K., Nakagawa, H. Physiological function of the histaminergic system in the rat brain. Proc. 8th Ann. Meet. Jap. Soc. Neurosci., Osaka, A-1C23, pp. 64 (1984). <\/p>\n

Cacabelos, R. Effects of religious education in a pseudocommunist community. Proc. 19th Kansai Cong. Jap. Assoc. Educ. Med., & 6th Jap. Speak. World Conf. Soc. Psychiatry, Osaka, pp. 14-15 (1984).<\/p>\n

Cacabelos, R., Yamatodani, A., Wada, H., Hariguchi, S., Nishimura, T. Histamine within the hypothalamo-hypophyseal system after bilateral adrenalectomy in rats. Proc. 22th Cong. Jap. Neurochem. Soc., Osaka (1983), Neurochem. Res., 9: 1165 (1984). <\/p>\n

Cacabelos, R., Yamatodani, A., Wada, H., Hariguchi, S., Tada, K., Takeda, M., Nishimura. T., Takagi, T., Sugita, N., Tanizawa, O. On the chronological changes in hypothalamic catecholamines and plasma ACTH after bilateral adrenalectomy. Proc. 22th Cong. Jap. Neurochem. Soc., Osaka (1983); Neurochem. Res., 9: 1165-1166 (1984). <\/p>\n

Yamatodani, A., Cacabelos, R., Watanabe, T., Wada, H. Effect of alpha-fluoromethylhistidine on circadian rhythms and the neuroendocrine system. Proc. 58th Jap. Pharmacol. Soc. Gen. Asamb., Tokyo, pp. 249 (1985). <\/p>\n

Nishimura, T., Cacabelos, R., Suzuki, H., Takagi, T., Hariguchi, S., Tanizawa, O. Age-related vasopressin and oxytocin changes in the CNS. Proc. XVIth Int. Cong. ISPNE, Kyoto, pp. 59 (1985). <\/p>\n

Cacabelos, R., Yamatodani, A., Watanabe, T., Hariguchi, S., Nishimura, T., Wada, H. Histaminergic neuromodulation of the corticotropinergic system. Proc. XVIth Int. Cong. ISPNE, Kyoto, pp. 99 (1985). <\/p>\n

Takagi, T., Otsuki, Y., Sugita, N., Tanizawa, O., Cacabelos, R., Nishimura, T. Age- and sex-related vasopressin and oxytocin changes in the CNS. Proc. 58th Jap. Cong. Endocrinol., Sendai, Folia Endocrinol. Jap., 61:388 (1985). <\/p>\n

Cacabelos, R. Biological verification of neurocybernetical hypothesis. 77th Neurosci. Meet., Osaka, Abst. l (1985). <\/p>\n

Niigawa, H., Cacabelos, R., Tanaka, S., Miyazawa, M., Suzuki, H., Takeda, M., Tada, K., Hariguchi, S., Nishimura, T. Changes in plasma and CSF amines and small peptides in dementia patients. Proc. 22th Cong. Geriat., Tokyo, Jpn. J. Geriat., 22:112 (1985). <\/p>\n

Cacabelos, R., Yamatodani, A., Fukui, H., Watanabe, T., Nishimura, T., Wada, H. Age- and sex-related changes in histamine and H-1 receptors in the hypothalamo-hypophyseal system after endocrine manipulation. Proc. 2nd Cong. ENEA, Milan, J. Endocrinol. Invest., 8(Suppl. 3):25 (1985). <\/p>\n

Nishimura, T., Niigawa, H., Cacabelos, R., Tada, K., Hariguchi, S. Changes in histamine and neuropeptides in plasma and CSF of dementia patients. Koseisho-shinkeishikan- kenkyu itakumi. Ronenki no chiho no byoin. Byotai chiryo ni kansuru kenkyu. Report 15, Tokyo (1985). <\/p>\n

Wada, H., Watanabe, T., Yamatodani, A., Cacabelos, R., Itoi, N., Kiyono, S., Seo, M., Nagai, K., Kanagawa, H. The distribution of the histaminergic neuron system and its physiological function in rat brain. Neurosci. Res. Suppl. 1: S112 (1985). <\/p>\n

Yamatodani, A., Cacabelos, R., Watanabe, T., Wada, H. Effects of alpha-fluoromethylhistidine (FMH) on circadian rhythm and neurosecretory system. Jap. J. Pharmacol., 39:87P (1985).<\/p>\n

Niigawa, H., Cacabelos, R., Hariguchi, S., Nishimura, T. Interactions of histamine and vasopressin in dementia. Proc. 6th Meet. Neuropsychiat., Osaka, Abst. 3 (1986). <\/p>\n

ltowi, N., Yamatodani, A., Goto, M., Cacabelos, R., Wada, H. Effect of alpha-fluoromethylhistidine administration on the plasma corticosterone level in mice. Jap. J. Pharmacol., 40:155P (1986). <\/p>\n

Cacabelos, R., Yamatodani, A., Watanabe, T., Takagi, T., Tanizawa, O., Hariguchi, S., Nishimura, T., Wada, H. Effects of alpha-fluoromethylhistidine on ACTH, vasopressin, and oxytocin in the hypothalamo-hypophyseal system and plasma. Neurochem. Res., 11:149 (1986).<\/p>\n

Cacabelos, R., Yamatodani, A., Miyake, A., Niigawa, H., Tada, K., Hariguchi, S., Nishimura, T., Wada, H. Functional interactions of histamine with GRF and GH. Acromegaly Centennial symposium, San Francisco, pp. 29 (1986). <\/p>\n

Niigawa, H., Cacabelos, R., Yamatodani, A., Wada, H., Tada, K., Hariguchi, S., Nishimura, T. Histamine as a neuromodulator of the vasopressinergic system. Neuroendocrinology, Abst. 1st Int. Cong. Neuroendocrinol., San Francisco, pp. 44 (1986). <\/p>\n

Cacabelos, R., Niigawa, H., Miyake, A., Hariguchi, S., Nishimura, T. Histaminergic modulation of the neuroendocrine system. Neuroendocrinology, Abst. 1st Int. Cong. Neuroendocrinol., San Francisco, pp. 78 (1986). <\/p>\n

Cacabelos, R., Niigawa, H., Miyake, A., Tada, K., Hariguchi, S., Nishimura, T. Histaminergic modulation of the gonadotropinergic system in aging. Jpn. J. Geriat., 23 (Suppl.):95 (1986). <\/p>\n

Niigawa, H., Cacabelos, R., Yamashita, T., Hariguchi, S., Nishimura, T. Age-related changes in histamine and vasopressin in the central nervous system. Jpn. J. Geriat., 23(Suppl.):95 (1986). <\/p>\n

Niigawa, H., Tada, K., Hariguchi, S., Nishimura, T., Cacabelos, R. Age-related changes in vasopressin in central and peripheral tissues. Folia Endocrinol. Jap., 62:963 (1986). <\/p>\n

Niigawa, H., Cacabelos, R., Miyake, A., Tada, K., Hariguchi, S., Nishimura, T. Influence of histamine on the gonadotropinergic system. Folia Endocrinol. Jap., 62:1136 (1986). <\/p>\n

Tanaka, J., Niigawa, H., Tada, K., Hariguchi, S., Nishimura, T., Cacabelos, R. Dose- and time-dependent GRF-induced vasopressin changes in the hypothalamo-hypophyseal system. Folia Endocrinol. Jap., 62: 1140 (1986). <\/p>\n

Cacabelos, R., Yamatodani, A., Fukui, H., Niigawa, H., Hariguchi, S., Nishimura, T., Wada, H. Influence of L-histidine, histamine and histamine antagonists on vasopressin in the hypothalamo-hypophyseal system. Folia Endocrinol. Jap., 62:963 (1986). <\/p>\n

Cacabelos, R., Niigawa, H., Tanaka, J., Murakoshi, K., G\u00f3mez-Pan, A., Rodr\u00edguez-Arnao, M.D., Nishimura, T. Behavioral effects of somatostatin and growth hormone-releasing hormone in dementia. Animal model and clinical implications. Somatostatin. Recent advances in basic research and clinical applications. Madrid, pp. 10-11 (1986). <\/p>\n

Niigawa, H., Tanaka, J., Murakoshi, K., Tada, K., Hariguchi, S., Nishimura, T., Cacabelos, R. GRF-induced vasopressin response in the hypothalamo-hypophyseal system. Abst. Int. Symp. GRF, growth hormone and somatomedin, Tokyo, pp. 25 (1986). <\/p>\n

Tanaka, J., Yamatodani, A., Niigawa, H., Miyake, A., Murakoshi, K., Tada, K., Hariguchi, S., Wada, H., Nishimura, T., Cacabelos, R. GRF-induced histamine response in the central nervous system and the effects of histamine and HA-antagonists on the GH response to GRF. Abst. Int. Symp. GRF, growth hormone and somatomedin, Tokyo, pp, 26 (1986). <\/p>\n

Cacabelos, R., Fukui, H., Yamatodani, A., Wada, H., Niigawa, H., Rodr\u00edguez-Arnao, M.D., G\u00f3mez-Pan, A., Nishimura, T. Influence of GRF on histamine, H-1 receptors and cAMP in the CNS. Abst. Int. Symp. GRF, growth hormone and somatomedin, Tokyo, pp. 26 (1986). <\/p>\n

Itoi, N., Yamatodani, A., Inagaki, N., Cacabelos, R., Wada, H. Effects of brain histamine depletion on circadian rhythms. Abst. 10th Jap. Cong. Neurosci., Osaka, pp. 48 (1986). <\/p>\n

Cacabelos, R., Yamatodani, A., Watanabe, T., Hariguchi, S., Nishimura, T., Wada, H. Age- and sex-related changes in histamine in the CNS, Kumamoto, Neurochem. Res., 11:1769-1770 (1986). <\/p>\n

Cacabelos, R., Yamatodani, A., Niigawa, H., Tanaka, J., Nishimura, T., Wada, H. Effects of somatostatin and growth hormone-releasing factor on histamine in the hypothalamo- hypophyseal system. Kyoto, Folia Endocrinol. Jap., 63 :434 (1987). <\/p>\n

Niigawa, H., Cacabelos, R., Yamatodani, A., Wada, H., Nishimura, T. Regulation of oxytocin release by brain histamine. Kyoto, Folia Endocrinol. Jap., 63:557 (1987). <\/p>\n

Niigawa, H., Tanaka, J., Murakoshi, K., Tada, K., Hariguchi, S., Nishimura, T., Cacabelos, R. GRF-induced vasopressin response in the hypothalamo-hypophyseal system. Tokyo, Endocrinol. Japon., 34(Suppl.):150 (1987). <\/p>\n

Tanaka, J., Yamatodani, A., Niigawa, H., Miyake, A., Murakoshi, K., Tada, K., Hariguchi, S., Wada, H., Nishimura, T., Cacabelos, R. GRF-induced histamine response in the central nervous system and the effects of histamine and HA-antagonists on the GH response to GRF, Tokyo, Endocrinol. Japon., 34(Suppl.):151 (1987). <\/p>\n

Cacabelos, R., Fukui, H., Yamatodani, A., Wada, H., Niigawa, H., Rodr\u00edguez-Arnao, M.D., G\u00f3mez-Pan, A., Nishimura, T. Influence of GRF on histamine, H-1 receptors and cAMP in the CNS. Tokyo, Endocrinol. Japon., 34(Suppl.):152 (1987). <\/p>\n

Cacabelos, R., Niigawa, H., Nishimura, T. Behavioral effects of somatostatin and growth hormone-releasing factor: A computerized analysis. XVIIIth Cong. ISPNE, Chapel Hill, Neuroendocr. Lett., 9:214 (1987). <\/p>\n

Niigawa, H., Murakoshi, K., Hariguchi, S., Nishimura, T., Cacabelos, R. A computerized analysis of the behavioral effects of L-histidine, histamine, and histamine antagonists. XVIIIth Cong. ISPNE, Chapel Hill, Neuroendocr. Lett., 9:216 (1987). <\/p>\n

Cacabelos, R., Niigawa, H., Nishimura, T. Antagonistic effects of somatostatin and growth hormone-releasing factor on behavior. Proc. 17th Jap. Cong. Psychopharmacol., Yokohama, pp. 107 (1987). <\/p>\n

Niigawa, H., Murakoshi, K., Nishimura, T., Cacabelos, R. Effects of chronic administration of L-histidine on behavior and learning. Proc. 17th Jap. Cong. Psychopharmacol., Yokohama, pp. 155 (1987).<\/p>\n

Murakoshi, K., Niigawa, H., Nishimura, T., Cacabelos, R. Computerized analysis of the effects of L-histidine, histamine and antihistaminics on behavioral parameters. Proc. l7th Jap. Cong. Psychopharmacol., Yokohama, pp. 154 (1987). <\/p>\n

Cacabelos, R., Nishimura, T., Rodr\u00edguez, A. Disfunci\u00f3n neuropeptid\u00e9rgica en la enfermedad de Alzheimer: Estrategias neuroqu\u00edmicas con fines diagn\u00f3sticos. XIII R. Soc. Esp. Psiquiat. Biol., Zaragoza, 25-27 Nov. (1987). <\/p>\n

Cacabelos, R. Influence of somatostatin and growth hormone-releasing factor on locomotor activity. A computerized analysis. Int. Meet. Mechan. Motor Control. Santiago de Compostela, 10- 11 Dic. (1987) <\/p>\n

Cacabelos, R., Niigawa, H., Nishimura, T., Rodr\u00edguez-Arnao, M.D., G\u00f3mez-Pan, A. Efectos antag\u00f3nicos de la somatostatina y el growth hormone-releasing factor sobre la histamina cerebral. VII Cong. Nac. Endocrinol., Granada, Endocrinolog\u00eda 34(Supl. 1):8 (1987). <\/p>\n

Niigawa, H., Fukui, H., Tada, K., Hariguchi, S., Nishimura, T., Wada, H., Cacabelos, R. Effects of hypophysiotropic neuropeptides on histamine H-1 receptors in the central nervous system, Proc. Int. Symp. Neurotransmitter Receptors. Receptor Mechanisms of neurotransmitters and neuropeptides. Hiroshima, 6-9 Oct., pp. 55 (1987). <\/p>\n

Cacabelos, R., Fukui, H., Niigawa, H., Wada, H., Nishimura, T. Age- and sex-related changes in brain histamine H-1 receptors. Proc. Int. Symp. Neurotransmitter Receptors. Receptor Mechanisms of neurotransmitters and neuropeptides. Hiroshima, 6-9 Oct., pp. 96 (1987). <\/p>\n

Cacabelos, R., Niigawa, H., Hariguchi, S., Nishimura, T. Effects of somatostatin and growth hormone-releasing factor on behavioral parameters: Computerized analysis in an animal model for senile dementia of the Alzheimer\u2019s type. Jpn. J. Geriat., 24: l l7 (1987). <\/p>\n

Niigawa, H., Cacabelos, R., Fukui, H., Yamatodani, A., Murakoshi, K., Nishimura, T., Wada, H. Histamine-induced vasopressin response in the hypothalamo-hypophyseal system of adult and old rats. Jpn. J. Geriat., 24: l l8 (1987). <\/p>\n

Cacabelos, R. An animal model of hyperkinesia. Symp. Neurotransmissio i Plasticitat Sinaptica, L\u00e9rida, 8-9 Abril, pp. 23 (1988). <\/p>\n

Couto, D.F., Niigawa, H., Rubia, F.J., Cacabelos, R. Antagonistic effects of growth hormone-releasing factor (GRF) and somatostatin (SS) on behavioral parameters in an animal model of Alzheimer\u2019s disease (AD). Symp. Neurotransmissio i Plasticitat Sinaptica, L\u00e9rida, 8-9 Abril, pp. 45 (1988). <\/p>\n

Fern\u00e1ndez, M., Otero, F., Niigawa, H., Cacabelos, R. Preliminary studies on the growth hormone-releasing factor (GRF) test as a diagnostic marker in Alzheimer\u2019s disease. Symp. Neurotransmissio i Plasticitat Sinaptica, L\u00e9rida, 8-9 Abril (1988). <\/p>\n

P\u00e9rez, A., Albarr\u00e1n, M.A., \u00c1lvarez, X.A., Cacabelos, R. Blunted plasma growth hormone (GH) response to GH-releasing factor (GRF) in patients with mental retardation. Stabilizing effects of\u00b4 GRF on EEG patterns in epilepsy. Symp. Neurotransmissio i Plasticitat Sinaptica, L\u00e9rida, 8-9 Abril (1988). <\/p>\n

Cacabelos, R., Niigawa, H., Nishimura, T. Growth hormone-releasing factor (GRF): Diagnostic marker and alternative therapy in Alzheimer\u2019s disease. 27th Scand. Cong. Neurol., Kuopio, Acta Neurol. Scand., 116 (Suppl. 77):90 (1988). <\/p>\n

P\u00e9rez, A., Albarr\u00e1n, M.A., Cacabelos, R. Biochemical studies of body fluids in senile dementia of the Alzheimer\u2019s type (SDAT) and multi-infarct dementia (MID). Correlation analysis between histamine and vasopressin in CSF and plasma. 27th Scand. Cong. Neurol., Kuopio, Acta Neurol. Scand., 116 (Suppl. 77):129 (1988). <\/p>\n

Albarr\u00e1n, M.A., P\u00e9rez, A., Niigawa, H., Cacabelos, R. GRF- induced GH response in mental retardation and epilepsy. 27th Scand. Cong. Neurol., Kuopio, Acta Neurol. Scand., 116 (Suppl. 77):141 (1988). <\/p>\n

Cacabelos, R. Actividad neurobiol\u00f3gica del GRF: Su papel como marcador diagn\u00f3stico en demencia senil y retraso mental. Symposium Sat\u00e9lite sobre posibilidades diagn\u00f3sticas del GRF(1-29)NH2. 22 Junio, Bilbao (1988). <\/p>\n

P\u00e9rez, A., Albarr\u00e1n, M.A., Cacabelos, R. Neuromodulaci\u00f3n histamin\u00e9rgica de la funci\u00f3n gonadotropa a nivel hipot\u00e1lamo-hipofisario. VIII Cong. Nac. Endocrinol., Bilbao, 23-25 Junio; Endocrinolog\u00eda 35:84 (1988). <\/p>\n

Fern\u00e1ndez, M., Couto, D.F., Cacabelos, R. Especificidad de la respuesta histamin\u00e9rgica central a la gonadectom\u00eda en funci\u00f3n de la edad y el sexo. VIII Cong. Nac. Endocrinol., Bilbao, 23-25 Junio; Endocrinolog\u00eda, 35:84 (1988). <\/p>\n

Otero, F., \u00c1lvarez, J.A., Cacabelos, R. Efectos del GRF sobre la histamina, receptores H-l y AMPc en el sistema hipot\u00e1lamo-hipofisario. VIII Cong. Nac. Endocrinol., Bilbao, 23-25 Junio; Endocrinolog\u00eda, 35:75 (1988). <\/p>\n

Niigawa, H., Cacabelos, R., Hariguchi, S., Nishimura, T. Implementation of the OUCEM-86: Behavioral effects of scopolamine. Proc. 10th Jap. Cong. Biol. Psychiat., Kyoto, pp. 132 (1988). <\/p>\n

Cacabelos, R., Niigawa, H., Nishimura, T. Preliminary studies with growth hormone-releasing factor (GRF) in Alzheimer\u2019s disease (AD): Animal model and clinical results. XIXth Int. Cong. ISPNE, Groningen; Neuroendocr. Lett., 10:232 (1988).<\/p>\n

Albarr\u00e1n, M.A., Fern\u00e1ndez, M., Otero, F., Cacabelos, R, Effects of histamine (HA) and antihistaminics on the corticotropin-releasing factor (CRF)-induced atrial natriuretic peptide (ANP) response in the hypothalamo- hypophyseal system. XIXth Int. Cong. ISPNE, Groningen; Neuroendocr., 10:225 (1988). <\/p>\n

P\u00e9rez, A., \u00c1lvarez, A., Couto, D.F., Cacabelos, R. Brain histamine system in aging. XIXth Int. Cong. ISPNE, Groningen; Neuroendocr. Lett., 10:268 (1988). <\/p>\n

Niigawa, H., Otsuki, Y., Iwata, I., Tanizawa, O., Nishimura, T., Cacabelos, R. Histaminergic modulation of the CRF-induced ANP response in the hypothalamo-hypophyseal system. Kyoto Symp. ANP, Sat. 8th Int. Cong. Endocrinol., 15-16 Julio (1988). <\/p>\n

Cacabelos, R., Niigawa, H., Iwata, I., Otsuki, Y., Takagi, T., Tanizawa, O., Nishimura, T. Histaminergic modulation of the GRF-induced ANP response in the hypothalamo-hypophyseal system. Kyoto Symp. ANP, Sat. 8th Int. Cong. Endocrinol., 15- 16 Julio (1988). <\/p>\n

Cacabelos, R., Ortiz, T., Rubia, F.J. Neurochemical assessment of the growth hormone-releasing factor (GRF)-induced hyperkinetic syndrome: Histaminergic activation in the cerebellum and brain cortex. Neurobiology of the cerebellar systems: A centenary of Ram\u00f3n y Cajal\u2019s description of the cerebellar circuits. Barcelona, 19-22 Oct. pp. 49 (1988).<\/p>\n

Cacabelos, R., Rodr\u00edguez, A. Hacia un abordaje sociobiol\u00f3gico de la demencia senil: Marcadores neurobiol\u00f3gicos y soporte psicosocial. VII Cong. Nac. Soc. Esp. Psiquiat. Psicopatol. Soc., Santiago de Compostela, 24-26 Oct., pp. 42 (1988). <\/p>\n

\u00c1lvarez, X.A., Cacabelos, R., Couto, D.F., Fern\u00e1ndez, M., Albarr\u00e1n, M.A., Otero, F., P\u00e9rez, A., Rodr\u00edguez, A. Factores psicosociales y cognitivos involucrados en el rendimiento acad\u00e9mico en psicolog\u00eda m\u00e9dica. VII Cong. Nac. Soc. esp. Psiquiat. Psicopatol. Soc., Santiago de Compostela, 24-26 Oct., pp. 48 (1988). <\/p>\n

Cacabelos, R., Otero, F., Fern\u00e1ndez, M., \u00c1lvarez, X.A., Albarr\u00e1n, M.A., P\u00e9rez, A., Lorenzo, A., Borr\u00e1s, C.G., Rodr\u00edguez, A. Growth hormone-releasing factor (GRF1-29NH2): Marcador diagn\u00f3stico en trastornos neuropsiqui\u00e1tricos. II Cong. Soc. Esp. Psiquiat. Biol., Madrid, 22-25 Nov., An. Psiquiatr\u00eda 4(Supl.1):33 (1988). <\/p>\n

Lorenzo, A., Pardi\u00f1as, M.C., Cacabelos, R., Salazar, I., Rodr\u00edguez, A. Marcadores neuroqu\u00edmicos en el alcoholismo (transferrina y GRF). II Cong. Soc. Esp. Psiquiat. Biol., Madrid, 22-25 Nov., An. Psiquiatr\u00cda 4(Supl.1):34 (1988). <\/p>\n

Cacabelos, R. Eficacia terap\u00e9utica del growth hormone-releasing factor (GRF) en la demencia senil: Estudios en un modelo animal de enfermedad de Alzheimer y resultados cl\u00ednicos preliminares. II Cong. Soc. Esp. Psiquiat. Biol., Madrid, 22-25 Nov., An. Psiquiatr\u00eda 4(Supl. 1):58-59 (1988). <\/p>\n

Albarr\u00e1n, A., P\u00e9rez, A., Cacabelos, R. Influencia del growth hormone-releasing factor (GRF) sobre hormona del crecimiento (GH) y par\u00e1metros electroencefalogr\u00e1ficos (EEG) en pacientes con retraso mental. II Cong. Soc. Esp. Psiquiat. Biol., Madrid, 22-25 Nov., An. Psiquiatr\u00eda 4(Supl. 1):81 (1988). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez, M., Otero, F., Albarr\u00e1n, M., P\u00e9rez, A., Ver\u00edsimo, J., Otero, T., Di\u00e9guez, C., Borr\u00e1s, C.G., Salazar, I., Lorenzo, A., Cacabelos, R., Rodr\u00edguez, A. Growth hormone-releasing factor (GRF): Marcador diagn\u00f3stico en neuropatolog\u00eda alcoh\u00f3lica. II Cong. Soc. Esp. Psiquiat. Biol., Madrid, 22-25 Nov., An. Psiquiatr\u00eda 4(Supl. 1):82 (1988). <\/p>\n

Fern\u00e1ndez, M., Otero, F., \u00c1lvarez, J.A., P\u00e9rez, A., Albarr\u00e1n, M.A., Niigawa, H., Nishimura, T., Cacabelos, R. Respuesta de GH inducida por GRF en pacientes con demencia senil tipo Alzheimer. II Cong. Soc. Esp. Psiquiat. Biol., Madrid, 22-25 Nov., An. Psiquiatr\u00eda 4(Supl. 1):90-91 (1988). <\/p>\n

Otero, F., P\u00e9rez, A., Albarr\u00e1n, M., \u00c1lvarez, J.A., Ver\u00edsimo, J., P\u00e9rez, T., Di\u00e9guez, C., Borr\u00e1s, C.G., Fr\u00e1iz, J., Rodr\u00edguez, A., Cacabelos, R, Eficacia diagn\u00f3stica del test de GRF en trastornos psiqui\u00e1tricos. II Cong. Soc. Esp. Psiquiat. Biol., Madrid, 22-25 Nov., An. Psiquiatr\u00eda 4(Supl. l):96 (1988). <\/p>\n

P\u00e9rez, A., Albarr\u00e1n, A., Fern\u00e1ndez, M., Otero, F., \u00c1lvarez, X.A., Cacabelos, R. Estudio bioqu\u00edmico de fluidos corporales en pacientes con demencia senil tipo Alzheimer y demencia multiinfarto. Marcadores monoamin\u00e9rgicos y neuropeptid\u00e9rgicos. II Cong. Soc. Esp. Psiquiat. Biol., Madrid, 22-25 Nov., An. Psiquiatr\u00eda 4(Supl.I):98-99 (1988). <\/p>\n

Rubia, F.J., Ortiz, T., Cacabelos, R. El problema del diagn\u00f3stico precoz en la enfermedad de Alzheimer. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife, 8-10 Dic., pp. 73-74 (1988). <\/p>\n

Cacabelos, R., Ortiz, T., Rubia, F.J. Marcadores neuroqu\u00edmicos en la enfermedad de Alzheimer. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife, 8-10 Dic., pp. 75-76 (1988). <\/p>\n

Ortiz, T., Cacabelos, R., Rubia, F.J. Mapas de actividad el\u00e9ctrica cerebral en la enfermedad de Alzheimer. XXIII Cong. Nac. Soc. Esp. Cienc, Fisiol., Tenerife, 8-10 Dic., pp. 79 (1988). <\/p>\n

Otero, F., \u00c1lvarez, J.A., Rubia, F.J., Cacabelos, R. Interacci\u00f3n de los sistemas histamin\u00e9rgico (SHA) y somatotropin\u00e9rgico (SST) a nivel central. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife, 8-10 Dic., pp. 155 (1988). <\/p>\n

Ortiz, T., Cacabelos, R., Rubia, F.J. Mapas de actividad el\u00e9ctrica cerebral en la enfermedad de Alzheimer. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife, 8-10 Dic., pp. 169 (1988). <\/p>\n

Fern\u00e1ndez, M., P\u00e9rez, A., Rubia, F.J., Cacabelos, R. Crononeurobiolog\u00eda del sistema histamin\u00e9rgico. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife, 8-10 Dic., pp. 170 (1988). <\/p>\n

\u00c1lvarez, X.A., Albarr\u00e1n, M.A., Niigawa, H., Rubia, F.J., Cacabelos, R. An\u00e1lisis computerizado de cambios inducidos por manipulaci\u00f3n farmacol\u00f3gica del sistema histamin\u00e9rgico. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife, 8-10 Dic., pp. 170 (1988). <\/p>\n

Cacabelos, R., Niigawa, H., Couto, D.F., Rubia, F.J. Estudio computerizado de los efectos de somatostatina (SS) y growth hormone-releasing factor (GRF) sobre par\u00e1metros conductuales. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife, 8-10 Dic., pp. 170 (1988). <\/p>\n

Cacabelos, R. Neurobiolog\u00eda del GRF: Marcador neuroendocrino en trastornos del sistema nervioso central. II Cong. Soc. Catal. Endocrinol., Barcelona, 17-18 Feb. (1989). <\/p>\n

Rodr\u00edguez, A., Cacabelos, R., Mateos, R. Estudio de la enfermedad de Alzheimer: Estrategias epidemiol\u00f3gicas y neuroqu\u00edmicas. II Symp. Intern. Gerontol. Psicogeriat., Murcia, 22-25 Febr. (1989). <\/p>\n

Cacabelos, R. Predictores biol\u00f3gicos en la enfermedad de Alzheimer. II Workshop sobre Marcadores Biol\u00f3gicos en Psiquiatr\u00eda. Societat Catalana de Psiquiatr\u00eda, Sitges, 31 Marzo (1989). <\/p>\n

Cacabelos, R. Bioqu\u00edmica. P\u00e9ptidos del sue\u00f1o. Symposium El Sue\u00f1o y sus Alteraciones. Academia de Ciencias M\u00e9dicas, Barcelona. 3 Mayo (1989). <\/p>\n

Cacabelos, R. Demencia senil. Marcadores diagn\u00f3sticos y alternativas terap\u00e9uticas. III Jornadas de Geriatr\u00eda. Colegio Oficial de M\u00e9dicos. Barcelona, Mayo 16-17 (1989). <\/p>\n

Cacabelos, R., Fern\u00e1ndez, M., Otero, F., \u00c1lvarez, X.A., Albarr\u00e1n, M.A., P\u00e9rez, A., Borr\u00e1s, C., Rodr\u00edguez, A. Marcadores neuroqu\u00edmicos para diagn\u00f3stico diferencial entre depresi\u00f3n involutiva y demencia senil. V Symposium Nacional del Comit\u00e9 Espa\u00f1ol para la Prevenci\u00f3n y Tratamiento de las Depresiones (PTD). La Toja, Mayo 26-27 (1989). <\/p>\n

Cacabelos, R. Bases neuroqu\u00edmicas de la depresi\u00f3n. I Jornadas Cient\u00edficas de la Sociedad Gallega de Psiquiatr\u00eda. Neuroqu\u00edmica de la Depresi\u00f3n. Santiago de Compostela, Mayo 29 (1989). <\/p>\n

Fari\u00f1as, F., Albarr\u00e1n, M.A., Garc\u00eda Alonso, L., Lodeiro, C., Cacabelos, R. Respuesta de GH inducida por GRF(1-29)NH2 en ni\u00f1os con talla baja asociada a trastornos del sistema inmune y metabolopat\u00edas. An. Esp. Pediatr\u00eda 30 (Supl. 37):54 (1989). <\/p>\n

Albarr\u00e1n, M.A., Fari\u00f1as, F., Lodeiro, C., Garc\u00eda Alonso, L., Cacabelos, R. Respuesta de Gh a GRF en ni\u00f1os con talla baja idiop\u00e1tica asociada a trastornos del sistema nervioso central. An. Esp. Pediatr\u00eda 30 (Supl. 37):43-44 (1989). <\/p>\n

Fari\u00f1as, F., \u00c1lvarez, X.A., Albarr\u00e1n, M.A., Garc\u00eda Alonso, L., Lodeiro, C., Cacabelos, R. Test de estimulaci\u00f3n con GRF(1-29)NH2 en ni\u00f1os con talla baja familiar y talla baja asociada a trastornos metab\u00f3licos e inmunol\u00f3gicos. VIII Reuni\u00f3n Nacional del F.I.S.s.s., Santander, Junio 1-3, pp. 132 (1989). <\/p>\n

Fern\u00e1ndez, M., \u00c1lvarez, X.A., Otero, F., Cornes, J.M., Lois, J.M., Borr\u00e1s, C., Rodr\u00edgues, A., Di\u00e9guez, C., Cacabelos, R. Test de GRF: Potencial marcador diagn\u00f3stico en patolog\u00eda neuropsiqui\u00e1trica. VIII Reuni\u00f3n Nacional del F.I.S.s.s., Santander, Junio 1-3, pp. 124 (1989). <\/p>\n

\u00c1lvarez, X.A., Couto, D.F., Aradas, Y., Casal, C., Bello, J.A., Cacabelos, R. Efectos del GRF(1-29)NH2 sobre la memoria a corto plazo (MCP). VIII Reuni\u00f3n Nacional del F.I.S.s.s., Santander, Junio 1-3, pp. 122 (1989). <\/p>\n

Otero, F., \u00c1lvarez, X.A., Fern\u00e1ndez, M., Ver\u00edsimo, J., Serrano, F., P\u00e9rez, T., Otero, T., Di\u00e9guez, C., Cacabelos, R. Respuesta de Gh a GRF en pacientes neum\u00f3patas y cardi\u00f3patas de edad avanzada. VIII Reuni\u00f3n Nacional del F.I.S.s.s., Santander, Junio 1-3, pp. 123 (1989).<\/p>\n

Cacabelos, R. Neuroendocrinolog\u00eda de la E.A. Simposium Alzheimer. Reuni\u00f3n Grupo Demencias SEN. Marcadores Biol\u00f3gicos y Perspectivas Terap\u00e9uticas en la Enfermedad de Alzheimer. Palma de Mallorca, Junio 8 (1989). <\/p>\n

Cacabelos, R. Neuroqu\u00edmica del sue\u00f1o. Workshop sobre Trastornos del Sue\u00f1o. Sanatorio Psiqui\u00e1trico de Conxo. Santiago de Compostela, Junio 16 (1989). <\/p>\n

Cacabelos, R. Neuroendocrine markers in Alzheimer\u2019s disease: New prospects for diagnosis and treatment. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Supl. 2):24 (1989). <\/p>\n

Fern\u00e1ndez, M., \u00c1lvarez, X.A., Otero, F., Couto, D.F., Pe\u00f1alva, A., Lorenzo, A., Borr\u00e1s, C.G., P\u00e9rez, A., Albarr\u00e1n, M.A., Rodr\u00edguez, A., Cacabelos, R. GRF-induced GH response in alcoholic patients. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2):77 (1989). <\/p>\n

Albarr\u00e1n, M.A., P\u00e9rez, A., Rubia, F.J., Cacabelos, R. GRF-induced GH response in mental retardation and attention-deficit hyperactivity disorders. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2): I 73 (1989). <\/p>\n

P\u00e9rez, A., Niigawa, H., Nishimura, T., Cacabelos, R. Studies of neuropeptides and monoamines in body fluids of patients with senile dementia (SDAT) and multi-infarct dementia (MID). 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2):175 (1989). <\/p>\n

\u00c1lvarez, X.A., Otero, F., Ver\u00edsimo, 3., Serrano, F., P\u00e9rez, T., Otero, T., Fern\u00e1ndez, M., Couto, D.F., Pe\u00f1alva, A., Cacabelos, R. GRF-induced GH response in lung and heart disease in the elderly. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2):177 (1989). <\/p>\n

Couto, D.F., \u00c1lvarez, X.A., Franco, A., Casas, X., Cerqueiro, J.M., de la Campa, A., Cacabelos, R. Effects of GRF(1-29)NH2 on cognitive functions: Neuropsychological and neuroendocrine assessment. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2):76 (1989). <\/p>\n

Otero, F., Fern\u00e1ndez, M., \u00c1lvarez, X.A., Albarr\u00e1n, M., P\u00e9rez, A., Couto, D.F., Borr\u00e1s, C.G., Cornes, M., Mallo, F., Rodr\u00edguez, A., Cacabelos, R. GRF-induced GH response in schizophrenia, depressive disorders and senile dementia of the Alzheimer type. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2):178 (1989). <\/p>\n

Fari\u00f1as, F., Albarr\u00e1n, M.A., Garc\u00eda Alonso, L., Lodeiro, C., Cacabelos, R. GRF-induced GH response in children with familiar short statures and idiopathic short stature associated with immunological and\/or metabolic disease. International Symposium on Growth and Reproduction, Lugo, June 27, pp. 31 (1989). <\/p>\n

Albarr\u00e1n, M.A., Fari\u00f1as, F., Lodeiro, C., Garc\u00eda Alonso, L., Cacabelos, R. GRF-induced GH response in children with short stature and CNS disorders. International Symposium on Growth and Reproduction, Lugo, June 27, pp. 29 (1989). <\/p>\n

Fern\u00e1ndez, M., P\u00e9rez, A., Albarr\u00e1n, M.A., Couto, D.F., Cacabelos, R. Age- and sex-related changes in brain histamine. Abstr. 12th Ann. Meet. Eur. Neurosci. Assoc. Turin 2-7 sept., 1989. Eur. J. Neurosci., Suppl. 2:22 (1989), <\/p>\n

\u00c1lvarez, X.A., Couto, D.F., Amigo, M.E., Fandi\u00f1o, J.M., Ares, Y., Garrote, A., Cacabelos, R. Short-term memory improvement after GRF(1-29)NH2 administration in humans. Abstr. 12th Ann. Meet. Eur. Neurosci. Assoc., Turin 2-7 Sept. 1989. Eur. J. Neurosci., Suppl. 2:210 (1989). <\/p>\n

Cacabelos, R., Yamatodani, A., Niigawa, H., Wada, H., Nishimura, T., Brandeis, L., Pearson, J. High levels of brain histamine in Alzheimer\u2019s disease. Abstr. 12th Ann. Meet. Eur. Neurosci. Assoc., Turin 2-7 Sept. 1989. Eur. J. Neurosci., Suppl. 2:238 (1989). <\/p>\n

\u00c1lvarez, X.A., Niigawa, H., Nishimura, T., Cacabelos, R. Behavioral changes induced by pharmacological manipulation of the histaminergic system. 21st Ann. Meet. Eur. Brain Behav. Soc., Turin 6-8 Sept. 1989. Eur. J. Neurosci., Suppl. 2:309 (1989). <\/p>\n

Cacabelos, R., Di\u00e9guez, C., Niigawa, H., Nishimura, T., Brandeis, L., Scanlon, M.F., Pearson, J. Growth hormone-releasing factor in Alzheimer\u2019s disease. 21st Ann. Meet. Eur. Brain Behav. Soc., Turin 6-8 Sept. 1989. Eur. J. Neurosci., Suppl. 2:311 (1989). <\/p>\n

Fern\u00e1ndez, M., Otero, F., \u00c1lvarez, X.A., Ver\u00edsimo, J., Serrano, F., P\u00e9rez, T., Rodr\u00edguez, A., Cacabelos, R. GRF-induced GH response in patients with heart disease and chronic alcoholism. 21st Ann. Meet. Eur. Brain Behav. Soc., Turin 6-8 Sept. 1989. Eur. J. Neurosci., Suppl. 2:313 (1989). <\/p>\n

Fern\u00e1ndez, M., P\u00e9rez, A., Rubia, F.J., Cacabelos, R. Chrononeurobiology of the histaminergic system. Abstr. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife 8-10 dic. 1988. Pfl\u00fcgers Archiv. Eur. J. Physiol., 414: (1989). <\/p>\n

\u00c1lvarez, X.A., Albarr\u00e1n, M.A., Niigawa, H., Rubia, F.J., Cacabelos, R. Behavioral changes after pharmacological manipulation of the histaminergic system. A computerized analysis. Abstr. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife 8-10 dic. 1988. Pfl\u00fcgers Archiv. Eur. J. Physiol., 414; (1989). <\/p>\n

Cacabelos, R., Ortiz, T., Rubia, F.J. Neurochemical markers for Alzheimer\u2019s disease. Abstr. XXIll Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife 8-10 dic. 1988. Pfl\u00fcgers Archiv. Eur. J. Physiol., 414:S24 (1989). <\/p>\n

Ortiz, T., Cacabelos, R., Rubia, F.J. Brain electrical activity mapping in Alzheimer\u2019s disease. Abstr. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife 8-10 dic. 1988. Pfl\u00fcgers Archiv. Eur. J. Physiol., 414:S23 (1989). <\/p>\n

Otero, F., \u00c1lvarez, J.A., Rubia, F.J., Cacabelos, R. Interaction between histaminergic (HAS) and somatotropinergic system (STS) at the central level. Abstr. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife 8-10 dic. 1988. Pfl\u00fcgers Archiv. Eur. J. Physiol., 414:S16 (1989). <\/p>\n

Otero, F., \u00c1lvarez, X.A., Agra, S., Alonso, J., Tabernero, J., Tortajada, I., Cacabelos, R. Respuesta de GH a GRF en pacientes con esquizofrenia. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 247 (1989). <\/p>\n

P\u00e9rez, A., Albarr\u00e1n, A., \u00c1lvarez, X.A., Fern\u00e1ndez, M., Otero, F.O., Cacabelos, R. Estudios neuroqu\u00edmicos preliminares sobre la demencia postmenop\u00e1usica tipo Alzheimer. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 247 (1989). <\/p>\n

Albarr\u00e1n, M.A., del Pino, J.L., M\u00edgmel, F., Mart\u00edn-Loeches, M., Exp\u00f3sito, F.J., Rubia, F.J., Cacabelos, R. Respuesta de GH a GRF en trastornos por d\u00e9ficit de atenci\u00f3n con hiperquinesia. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 248 (1989). <\/p>\n

\u00c1lvarez, X.A., Couto, D.F., Fern\u00e1ndez, M., Otero, F., Albarr\u00e1n, M., P\u00e9rez, A., Cacabelos, R. Influencia del sistema somatotropin\u00e9rgico (SST) sobre funciones cognitivas. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 248 (1989). <\/p>\n

Cacabelos, R., Di\u00e9guez, C., Niigawa, H., Nishimura, T., Brandeis, L., Scanlon, M.F., Pearson, J. Alteraciones selectivas de somatoliberina (GRF) en el SNC de pacientes con enfermedad de Alzheimer. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 249 (1989). <\/p>\n

Fern\u00e1ndez, M., Cacabelos, R. Respuesta de GH a GRF en anorexia nerviosa. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 249 (1989). <\/p>\n

Cacabelos, R. Disfunci\u00f3n amino-peptid\u00e9rgica en la enfermedad de Alzheimer. Nuevos hallazgos neuroqu\u00edmicos. Simposium sobre \u201cBases neuroqu\u00edmicas del envejecimiento cerebral: Enfermedad de Alzheimer\u201d. Granada 6-7 Oct. (1989). <\/p>\n

Albarr\u00e1n, M.A., P\u00e9rez, A., Fern\u00e1ndez, M., Otero, F., \u00c1lvarez, J.A., Borr\u00e1s, C., Rodr\u00edguez, A., Cacabelos, R. GRF test: A potential diagnostic marker in psychiatric disorders. VIII World Congr. Psychiatry. Athens, 12-19 Oct. Psychiatry Today. Accomplishments and Promises. Excerpta Medica. International Congress Series 899:341 (1989). <\/p>\n

Cacabelos, R., Di\u00e9guez, C., Niigawa, H., Nishimura, T., Scanlon, M.F., Pearson, J. Growth hormone-releasing factor (GRF) in senile dementia. VIII World Congr. Psychiatry. Athens, 12-19 Oct. Psychiatry Today. Accomplishments and promises. Excerpta Medica. International Congress Series 899:730 (1989). <\/p>\n

Cacabelos, R., Yamatodani, A., Niigawa, H., Wada, H., Nishimura, T., Pearson, J. Brain histamine in senile dementia. VIII World Congr. Psychiatry. Athens, 12-19 Oct. Psychiatry Today. Accomplishments and Promises. Excerpta Medica. International Congress Series 899:730 (1989). <\/p>\n

Rodr\u00edguez, A., Mateos, R., Cacabelos, R. Diagn\u00f3stico y estrategias de seguimiento en demencias. VIII World Congr. Psychiatry. Athens, 12-19 Oct. Psychiatry Today. Accomplishments and Promises. Excerpta Medica. International Congress Series 899:730 (1989).<\/p>\n

P\u00e9rez, A., Albarr\u00e1n, M., \u00c1lvarez, X.A., Fern\u00e1ndez, M., Otero, F., Cornes, J.M., Rodr\u00edguez, A., Cacabelos, R. GRF-induced GH response in Alzheimer\u2019s disease. VIII World Congr. Psychiatry. Athens, 12-19 Oct. Psychiatry Today. Accomplishments and promises. Excerpta Medica. International Congress Series 899:735 (1989). <\/p>\n

Cacabelos, R., Di\u00e9guez, C., Niigawa, H., Scanlon, M.F., Pearson, J., Nishimura, T. Growth hormone-releasing factor (GRF) in Alzheimer\u2019s disease. Alzheimer\u2019s and Parkinson\u2019s diseases. Basic and therapeutic strategies. The second International Conference. Kyoto, 6-10 Nov. (1989). <\/p>\n

Cacabelos, R. Marcadores neurol\u00f3gicos en alcoholismo. XIV Reun. Nac. Soc. Esp. Psiquiat. Biol., Santander, 2-3 Nov, 1989. Anales Psiquiatr\u00eda, 5(Supl.II):3-4 (1989). <\/p>\n

\u00c1lvarez, X.A., Couto, D.F., Cacabelos, R. Efectos de somatoliberina (GRF(1-29)NH2) y GH biosint\u00e9tica (Saizen) sobre actividad psicomotriz en ratas. X1V Reun. Nac. Soc. Esp. Psiquiat Biol., Santander, 2-3 Nov. 1989. Anales Psiquiatr\u00eda 5(Supl.II):49-50 (1989). <\/p>\n

Albarr\u00e1n, M.A., Salazar, I., P\u00e9rez, I., Rodr\u00edguez, A., Cacabelos, R. Hiporrespuesta de GH a GRF en toxic\u00f3manos. XIV Reun, Nac. Soc. Esp. Psiquiat. Biol., Santander, 2-3 Nov. 1989. Anales Psiquiatr\u00eda 5(Supl. II):50 (1989). <\/p>\n

P\u00e9rez, A., Fern\u00e1ndez, M., Cornes, J.M., Albarr\u00e1n, M.A., Cacabelos, R. Respuesta de GH a GRF (growth hormone-releasing factor) en pacientes con demencia multiinfarto (DM1). XIV Reun. Nac. Soc. Esp. Psiquiat. Biol., Santander, 2-3 Nov. 1989. Anales Psiquiatr\u00eda 5(Supl. II):50-51 (1989). <\/p>\n

Fern\u00e1ndez, M., Albarr\u00e1n, M.A., Cornes, J.M., Cacabelos, R. Respuesta de GH a GRF en trastornos depresivos. XIV Reun. Nac. Soc. Esp. Psiquiat. Biol., Santander, 2-3 Nov. 1989. Anales Psiquiatr\u00eda, 5(Supl.II):51 (1989). <\/p>\n

Otero, F., Tortajada, I., Alonso, J., Blanco, J., Tabernero, J., Agra, S., Cornes, J.M., Cacabelos, R, Test de GRF: Potencial marcador diagn\u00f3stico en esquizofrenia. XIV Reun. Nac. Soc. Esp. Psiquiat. Biol., Santander, 2-3 Nov. 1989. Anales Psiquiatr\u00eda 5(Supl.II):51-52 (1989). <\/p>\n

Cacabelos, R. Bases neurobiol\u00f3gicas de los trastornos depresivos. Symposium. Avances en patolog\u00eda depresiva. Oviedo, 1 Dic. (1989). <\/p>\n

Niigawa, H., Cacabelos, R., Hariguchi, S., Nishimura, T. Changes in CAT activity and VP content in the aging rat brain. Jpn. J. Geriat., 26:134 (1989). <\/p>\n

Niigawa, H., Cacabelos, R., Hariguchi, S., Nishimura, T. Effects of i.c.v. injections of arginine-vasopressin on rat behavior. Step-down type passive avoidance behavior studied in the OUCEM-86. Psychopharmacology Abstract Book, pp. 108 (1989). <\/p>\n

Cacabelos, R. Growth hormone-releasing factor (GRF): Neurobiology and applications in clinical neuroscience. Emil Aaltonen Symposium. Healthy Brain. Tampere, Finland, 22.3.90. Tampereen Laakaripaivat-90, Luennot 11:81-82 (1990). <\/p>\n

Cacabelos, R. Alzheimer\u2019s disease: Update. Physiopathology. Advances in Psychiatry 90. Amsterdam, 19.4.90. <\/p>\n

Cacabelos, R., Fern\u00e1ndez, M., Fari\u00f1as, F., Otero, F., Rubia, F.J. Histidine decarboxylase (HDC) inhibition induced by \uf061-FMH provokes learning-related hypokinetic activity. XIX Meeting Eur. Histamine Res. Soc., Kuopio (Finland), 16-20 Mayo, pp. 9 (1990). <\/p>\n

Cacabelos, R., Niigawa, H., Rivier, J., Vale, W. Brain histamine synthesis blockade with \uf061-FMH dysregulates the corticotropinergic system: Influence of \uf061-FMH and adrenalectomy (ADX) on CRF. XIX Meeting Eur. Histamine Res. Soc., Kuopio (Finland), 16-20 Mayo, pp. 41 (1990). <\/p>\n

Cacabelos, R. Nuevas estrategias terap\u00e9uticas en la enfermedad de Alzheimer: Factores neurotr\u00f3ficos, neurop\u00e9ptidos y agentes nootropos. II Reuni\u00f3n Nac. Soc. Esp. Gerontopsiquiat. Psicogeriat., Oviedo, 31 Mayo-2 Junio (1990), <\/p>\n

Cacabelos, R. Bases gen\u00e9ticas de los trastornos mentales y marcadores neuroqu\u00edmicos. Jornada Cient\u00edfica. La psiquiatr\u00eda en el contexto de las neurociencias actuales. Pazo de Mari\u00f1\u00e1n, La Coru\u00f1a, 9 Junio (1990). <\/p>\n

Cacabelos, R. Eficacia de fluoxetina en el contexto de los ensayos cl\u00ednicos. V Jornada Cient\u00edfica, Asoc. Gallega Psiquiatr\u00eda. Estado actual del tratamiento de la depresi\u00f3n. La Coru\u00f1a, 22 Junio (1990).<\/p>\n

\u00c1lvarez, X.A., Cacabelos, R. Behavioral changes induced by peripheral manipulation of the somatotropinergic system. 2nd Int. Cong. Neuroendocrinology, Bordeaux, France, June 24-29, 1990. Neuroendocrinology, 52 (Suppl. 1):64 (1990). <\/p>\n

Cacabelos, R. Estrategias con neurop\u00e9ptidos (NPs) y factores neurotr\u00f3ficos en la enfermedad de Alzheimer (EA). Simposio Multidisciplinario sobre Enfermedad de Alzheimer y otras Demencias. Pamplona, 16-19 Sept., pp. 31 (1990). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Cacabelos, R. Interleukina-l (IL-1) en la enfermedad de Alzheimer. Simposio Multidisciplinario sobre Enfermedad de Alzheimer y otras Demencias. Pamplona, 16-19 Sept., pp. 45 (1990). <\/p>\n

Cacabelos, R. Neurobiolog\u00eda del GRF: Aspectos b\u00e1sicos y cl\u00ednicos. Symposium Sat\u00e9lite de Neurobiolog\u00eda. XXIV Congr. Nac. Soc. Esp. Cienc. Fisiol., Madrid, 24-25 Sept., N-3 (1990). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Mallo, F., Cacabelos, R. Estudios sobre actividad locomotriz y aprendizaje de evitaci\u00f3n pasiva en ratas con dieta deficiente en vitamina A. XXIV Congr. Nac. Soc. Esp. Cienc. Fisiol., Madrid 26-29 Sept., 130 (1990). <\/p>\n

Franco, A., \u00c1lvarez, X.A., Mallo, F., Cacabelos, R. Efectos de GHRP-6 sobre actividad locomotriz y aprendizaje de evitaci\u00f3n pasiva en ratas. XXIV Congr. Nac. Soc. Esp. Cienc. Fisiol., Madrid 26-29 Sept., 131 (1990). <\/p>\n

Cacabelos, R. Neurobiolog\u00eda del GRH: Aspectos b\u00e1sicos y cl\u00ednicos. Psiconeuroendocrinolog\u00eda. Jornadas de Endocrinolog\u00eda. Consejo General de M\u00e9dicos, Madrid 18 Oct., (1990). <\/p>\n

Cacabelos, R. Bases neurofisiol\u00f3gicas de la ansiedad y depresi\u00f3n. I Reuni\u00f3n da Sociedade Galega de Xerontolox\u00eda e Xeriatr\u00eda. A Toxa, Pontevedra, 19-21 Oct., (1990). <\/p>\n

Cacabelos, R., \u00c1lvarez, X.A. Funci\u00f3n neuroinmune en trastornos mentales. XV Reuni\u00f3n Nacional Soc. Esp. Psiquiat. Biol., C\u00f3rdoba 1-3 Nov., 1990. An. Psiq., 6 (Supl.II):13 (1990). <\/p>\n

Cacabelos, R. Neuroqu\u00edmica y marcadores biol\u00f3gicos en las demencias. XV Reuni\u00f3n Nac. Soc. Esp. Psiquiat. Biol., C\u00f3rdoba 1-3 Nov., 1990. Simposio Actualizaci\u00f3n en las demencias. 2 Nov. (l990) <\/p>\n

Cacabelos, R., Franco-Maside, A., \u00c1lvarez, X.A. Bases neurobiol\u00f3gicas y psicopatolog\u00eda del complejo demencia-SIDA. Jornadas sobre SIDA y Salud Mental. Zaragoza 16-17 Nov. (1990). <\/p>\n

Franco, A., \u00c1lvarez, X.A., Mallo, F., D\u00edaz, E., Cacabelos, R. Deterioro del aprendizaje por evitaci\u00f3n pasiva en ratas con dieta deficiente en \u00e1cido retinoico. X Congr. Nac. Soc. Esp Endocrinolog\u00eda. Santiago de Compostela, 5-7 Junio, 1991. Endocrinolog\u00eda, 38(Supl.2):39 (1991). <\/p>\n

\u00c1lvarez, X., Franco, A., Mallo, F., D\u00edaz, E., Cacabelos, R. Efecto del hexap\u00e9ptido liberador de hormona de crecimiento (GHRP-6) sobre conducta en ratas. X Congr. Nac. Soc. Esp. Endocrinolog\u00eda. Santiago de Compostela, 5-7 Junio, 1991. Endocrinolog\u00eda, 38(Supl.2);44-45 (1991). <\/p>\n

Franco-Maside, A., \u00c1lvarez, X.A., Cacabelos, R. Atrial natriuretic peptide in Alzheimer\u2019s disease. 5th World Congr. Biol. Psychiatry, Florence, Italy, June 9-14, 1991. Biol. Psychiatry 29\/11S:479S-480S (1991). <\/p>\n

\u00c1lvarez, X.A., Franco-Maside, A., Cacabelos, R. GRF-induced GH response in Alzheimer\u2019s disease (AD), multi-infarct dementia (MID), and pseudodementia (PD). 5th World Congr. Biol. Psychiatry, Florence, Italy, June 9-14, 1991. Biol. Psychiatry, 29\/l l S:685S (1991). <\/p>\n

Cacabelos, R., Franco-Maside, A., \u00c1lvarez, X.A. Interleukin-l (IL-1) in Alzheimer\u2019s disease (AD). 5th World Congr. Biol, Psychiatry, Florence, Italy, June 9-14, 1991. Biol. Psychiatry, 29\/11S:687S (1991). <\/p>\n

Cacabelos, R., Barquero, M., Garc\u00eda, P., \u00c1lvarez, X.A., Varela de Seijas, E. Cerebrospinal fluid interleukin 1\uf062 in Alzheimer\u2019s disease. XXII Congr. Intern. Soc. Psychoneuroendocrinology, Siena, Italy, June 17-20, 1991. Neuroendocr. Lett., 13 :206 (1991). <\/p>\n

Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Acute effects of growth hormone releasing factor (GRF) on cognitive function in aging and senile dementia. XXII Congr. intern. Soc. Psychoneuroendocrinology, Siena, Italy, June 17-20, 1991. Neuroendocr. Lett., 13:213 (1991). <\/p>\n

\u00c1lvarez, X.A., Vara, E., Barquero, M., Garc\u00eda, P., Moreno, A., Varela de Seijas, E., Cacabelos, R. Cerebrospinal fluid (CSF) insulin in Alzheimer\u2019s disease. XXII Congr. Intern. Soc. Psychoneuroendocrinology. Siena, Italy, June 17-20, 1991. Neuroendocr. Lett., 13:249 (1991). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez, L., Caso, J., Cacabelos, R. Interleukin-l in senile dementia. Correlation with physiological and cognitive parameters. Il Eur. Congr. Gerontol., Madrid 11-14 Sept., 1991. Rev. Esp. Geriat. Gerontol., 26 (Supl.1):202 (1991). <\/p>\n

Franco, A., \u00c1lvarez, X.A., Caso, J., Fern\u00e1ndez, L., Cacabelos, R. Atrial natriuretic peptide in senile dementia. Il Eur. Congr. Gerontol., Madrid 11-14 Sept., 1991. Rev. Esp. Geriat. Gerontol., 26 (Supl. 1):202 (1991). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Caso, J., Fern\u00e1ndez, L., Cacabelos, R. GRF-induced GH response in senile dementia. Correlation between neurophysiological and neuroendocrine parameters. II Eur. Congr. Gerontol., Madrid 11-l4 Sept., 1991. Rev. Esp. Geriat. Gerontol., 26 (Supl. l):203 (l99l). <\/p>\n

Cacabelos, R. Brain histamine: Neuroendocrine regulator in physiological and pathological conditions. Symposium Biogenic Amines. 1st Int. Cong. Vitamins and Biofactors in Life Sciences (ICVB): Kobe, Japan, Sept. 16-20; pp. 53 (1991). <\/p>\n

Cacabelos, R., \u00c1lvarez, X.A. Environmental factors, development and cognition: Influence of the somatotropinergic system (STS) on mental function and psychomotor activity. VIth Int. Congr. Auxology. Madrid, 15-19 Sept. (1991). <\/p>\n

P\u00e9rez-Trull\u00e9n, J.M., V\u00e1zquez-Andr\u00e9, M.L., \u00c1lvarez, X.A., Cacabelos, R. La onda P300 como m\u00e9todo diagn\u00f3stico en la enfermedad de Alzheimer. IV Congr. Soc. Esp. Neurociencia. Alicante 30.9-3.10, 25.16-P (1991). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Mallo, F., D\u00edaz, E., Cacabelos, R. El tratamiento con testosterona revierte el deterioro del aprendizaje inducido por d\u00e9ficit de \u00e1cido retinoico en ratas. IV Cong. Soc. Esp. Neurociencia, Alicante 30.9-3.10, 32-16-P (1991). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Cacabelos, R. Efectos del GRF(1- 29)NH2 sobre funci\u00f3n cognitiva en la demencia senil. IV Cong. Soc. Esp. Neurociencia, Alicante 30.9-3.10, 32-17P (1991). <\/p>\n

Cacabelos, R. Marcadores gen\u00e9ticos en Psiquiatr\u00eda. XVI Reun. Nac. Soc. Esp. Psiquiatr\u00eda Biol\u00f3gica, Vitoria, 7-9 Nov., (1991). <\/p>\n

Franco, A., \u00c1lvarez, X.A., G\u00f3mez-Trigo, J., Caama\u00f1o, J., Cacabelos, R. Influencia del GRF sobre funci\u00f3n mental en la demencia senil. XVI Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: 111 (1991).<\/p>\n

\u00c1lvarez, X.A., Franco, A., G\u00f3mez-Trigo, J., Caama\u00f1o, J., Cacabelos, R. Interleucina-1 central y perif\u00e9rica en la demencia senil. XVI Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: 111 (1991). <\/p>\n

\u00c1lvarez, X.A., Franco, A., G\u00f3mez-Trigo, J., Caama\u00f1o, J., Vara, E., Barquero, M., Garc\u00eda, P., Moreno, A., Varela de Seijas, E., Cacabelos, R. Insulina central en la demencia senil. XVI Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: 112 (1991). <\/p>\n

P\u00e9rez-Trull\u00e9n, J.M., V\u00e1zquez Andr\u00e9, M.L., Cacabelos, R. Estudio de la prosodia en la enfermedad de Alzheimer. XVI Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: 113 (1991). <\/p>\n

P\u00e9rez-Trull\u00e9n, J.M., V\u00e1zquez Andr\u00e9, M.L., Caso, J., \u00c1lvarez, X.A., Franco, A., Cacabelos, R. Alteraciones del lenguaje en la enfermedad de Alzheimer. XV1 Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: l l3 (1991). <\/p>\n

P\u00e9rez-Trull\u00e9n, J.M., V\u00e1zquez-Andr\u00e9, M.L., Modrego, A., \u00c1lvarez, X.A., Cacabelos, R. Trastornos de memoria y P300 en la enfermedad de Alzheimer. XVI Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: 114 (1991), <\/p>\n

Cacabelos, R. Nuevos aspectos de la etiopatogenia de la enfermedad de Alzheimer. Workshop internacional. Envejecimiento y Farmacolog\u00eda Preventiva. Alicante, 13-14 Dic., (1991). <\/p>\n

Cacabelos, R. Psicofarmacolog\u00eda molecular de la enfermedad de Alzheimer, Nuevas estrategias terap\u00e9uticas. IV Congr. Intern. Farmacoterapia y Nutrici\u00f3n Geri\u00e1trica, Valencia, 26-29.2.92 (1992). <\/p>\n

Cacabelos, R. Neurobiolog\u00eda molecular de la enfermedad de Alzheimer. Prospecciones terap\u00e9uticas. I Symposium de Psicobiolog\u00eda. Perspectivas Actuales de Investigaci\u00f3n en Psicobiolog\u00eda. La Coru\u00f1a, 9-13.3.92 (1992). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. GRF-induced GH response in opiate addicts. Int. Meeting. Strategies for studying CNS active compounds: Models, screens and clinical syndromes. Madrid, 26 April-2 May, 1992. Behav. Pharmacol., 3(Suppl. 1):60 (1992). <\/p>\n

Fern\u00e1ndez-Novoa, L., Pastuzko, A., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Effects of neurocatin on the release and level of serotonin in synaptosomes from the rat brain. Int. Meeting. Strategies for studying CNS active compounds: Models, screens and clinical syndromes. Madrid, 26 April-2 May, 1992. Behav. Pharmacol., 3(Suppl. 1):94 (1992). <\/p>\n

Fern\u00e1ndez-Novoa, L., Pastuszko, A., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. The effects of neurocatin on serotonin metabolism in synaptosomes from the rat brain. Int. Meeting. Strategies for studying CNS active compounds: Models, screens and clinical syndromes. Madrid, 26 April-2 May, 1992. Behav. Pharmacol., 3(Suppl. 1):94-95 (1992). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Positive effects of GHRP-6 on passive avoidance behavior in a new experimental paradigm. Int. Meeting. Strategies for studying CNS active compounds: Models, screens and clinical syndromes. Madrid, 26 April-2 May, 1992. Behav. Pharmacol., 3(Suppl. 1):84-85 (1992). <\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., Franco-Maside, A., \u00c1lvarez, A. Neuroendocrine and neuroimmune modulatory effects of brain histamine: physiological responses and pathological implications in Alzheimer\u2019s disease. XXI Ann. Meeting European Histamine Research Society. Torremolinos, M\u00e1laga, 13-17 May, 1992, pp. 90 (1992). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of betahistine on locomotor activity and passive avoidance behavior in rats. XXI Ann. Meeting European Histamine Research Society. Torremolinos, M\u00e1laga, l3-17 May, pp. 95 (1992). <\/p>\n

Cacabelos, R. Funci\u00f3n neuroinmune en trastornos mentales: papel de la histamina cerebral como neuroinmunomodulador en condiciones fisiol\u00f3gicas y patol\u00f3gicas. XII Congr. Asoc. Latinoamer. Soc. Biol. Med. Nuclear. Madrid, Mayo 25-28 (1992). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Dose- and time-dependent effects of histamine on hypothalamic levels of interleukin-1\uf062 in rats. XXI Ann. Meeting European Histamine Research Society. Torremolinos, M\u00e1laga, 13-17 May, pp. 107 (1992). <\/p>\n

Cacabelos, R. Hacia un tratamiento etiopatog\u00e9nico de la enfermedad de Alzheimer: Psicofarmacolog\u00eda molecular. Mesa Redonda: Nuevas alternativas terap\u00e9uticas en la enfermedad de Alzheimer, III Congr. Nac. Soc. Esp. Psiquiat. Biol., Pamplona 17-20 Junio, pp. 63-64 (1992). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Efectos positivos de la betahistina sobre el deterioro del aprendizaje inducido por escopolamina en ratas. III Congr. Nac. Soc. Esp. Psiquiat. Biol., Pamplona 17-20 Junio, pp. 259-260 (1992). <\/p>\n

Franco, A., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Efectos del tratamiento con citicolina sobre funci\u00f3n cognitiva y niveles s\u00e9ricos de interleucina-1\uf062 en la demencia senil, III Congr. Nac. Soc. Esp. Psiquiat. Biol., Pamplona 17-20 Junio, pp. 260-261 (1992). <\/p>\n

Caama\u00f1o, J., Valle-lncl\u00e1n, F., Cacabelos, R. Velocidades de flujo sangu\u00edneo en arteria cerebral media de pacientes con demencia vascular: evaluaci\u00f3n mediante ultrasonograf\u00eda Doppler transcraneal. III Congr. Nac. Soc. Esp. Psiquiat. Biol., Pamplona 17-20 Junio (1992). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Age- and sex-related serum growth hormone (GH) levels in psychiatric patients and healthy control subjects. A correlation study between GH values and cognitive performance. Proc. 18th Collegium Internationale Neuro- Psychopharmacologicum Congress. Nice, June 28-July 2, 1992. Clin. Neuropharm., 15(Suppl. 1-B);283B (1992). <\/p>\n

Cacabelos, R., Franco-Maside, A., \u00c1lvarez, X.A. Therapeutic effects of CDP-Choline on cognition and cardiovascular parameters in Alzheimer\u2019s disease. Proc. 18th CINP Congress, Nice, June 28-July 2, 1992. Clin. Neuropharmacol., 15(Suppl. 1-B):474B (1992). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of betahistine on behavior in rats. Preliminary results. Proc. 18th CINP Congress, Nice, June 28-July 2, 1992. Clin. Neuropharmacol., 15(Suppl. 1-B) :478B (1992). <\/p>\n

Fern\u00e1ndez-Novoa, L., Pastuszko, A., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Inhibition of monoamine oxidase A by neurocatin in synaptosomes from rat brain. Proc. 18th CINP Congress, Nice, June 28-July 2, 1992. Clin. Neuropharmacol., 15(Suppl. 1-B):590B (1992).<\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Franco-Maside, A., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F. Influence of CDP-Choline on cognition and interleukin-1\uf062 in Alzheimer\u2019s disease (AD) and multi-infarct dementia (MID). The Third International Conference on Alzheimer\u2019s Disease and Related Disorders. Padova, July 12-17, 1992. Neurobiol. Aging 13(Suppl. 1):S134-S135 (1992). <\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F., Secades, J., Novell, R., Lozano, R. Therapeutic effects of CDP-Choline in Alzheimer\u2019s disease and multi-infarct dementia. International Conference on Neurodegenerative Disease. New Approaches to Treatment. London. 15-16 Sept., 1992.<\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F., Secades, J., Novell, R., Lozano, R. Effects of CDP-Choline in Alzheimer\u2019s disease and multi-infarct dementia: Influence on cognition, mood, and interleukin-\uf062 production. 8th lnt. Meeting and Conference. Alzheimer Disease International (ADI). Brussels, Sept. 25-27 (1992). <\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F., Secades, J., Novell, R., Lozano, R. Therapeutic effects of CDP-Choline in Alzheimer\u2019s disease and multi-infarct dementia. Int. Conf. Neurodegenerative Disease. New Approaches to Treatment. London, Sept. 15-16 (1992). <\/p>\n

Cacabelos, R. Basic mechanisms and classification of memory disorders with special reference to dementias. Workshop: Technical aids for memory and environmental control in dementia and other cognitive impairment. NORAGE \u201992. First Congress of the Nordic Society for Research in Brain Aging. Sheraton Copenhagen Hotel, Copenhagen, Denmark, Oct. 9-10 (1992). <\/p>\n

Cacabelos, R. Estrategias terap\u00e9uticas en la enfermedad de Alzheimer. Avances en la enfermedad de Alzheimer y relaci\u00f3n de A.F.A.F. con las l\u00edneas de investigaci\u00f3n en Espa\u00f1a. 1\u00aa Reuni\u00f3n Asociaci\u00f3n Familiares de Alzheimer de Andaluc\u00eda y 1\u00ba Congreso de la Federaci\u00f3n Espa\u00f1ola de Asociaciones de Familiares de enfermos de Alzheimer. M\u00e1laga, Oct. 1-2 (1992). <\/p>\n

Valle-lncl\u00e1n, F., Caama\u00f1o, J., Cacabelos, R. Functional relationship between blood-flow velocity in middle cerebral artery and EEG spectral analysis. Vth Congr. Eur. College Neuropsychopharmacology. Marbella, 18-21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:326 (1992). <\/p>\n

Franco, A., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Betahistine attenuates learning impairment induced by scopolamine in rats. Vth Congr. Eur. College Neuropsychopharmacology. Marbella, 18-21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:354 (1992). <\/p>\n

Caama\u00f1o, J., Valle-lncl\u00e1n, F., Cacabelos, R. Parieto-temporal hypoperfusion in Alzheimer\u2019s disease measured by transcranial doppler ultrasonography. Vth Congr. Eur. College Neuropsychopharmacology. Marbella, 18-21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:360 (1992). <\/p>\n

Fern\u00e1ndez-Novoa, L., P\u00e9rez-Trull\u00e9n, J.M., Cacabelos, R. Serum histamine in Alzheimer\u2019s disease and multi-infarct dementia. Vth Congr. Eur. College Neuropsychopharmacology, Marbella 18- 21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:360 (1992). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Central and peripheral interleukin-l in Alzheimer\u2019s disease. Vth Congr. Eur. College Neuropsychopharmacology, Marbella 18- 21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:361-362 (1992). <\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Franco-Maside, A., Fern\u00e1ndez- Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F. Effect of CDP-Choline on cognition and immune function in Alzheimer\u2019s disease and multi-infarct dementia. Vth Congr. Eur. College Neuropsychopharmacology, Marbella 18-21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:362-363 (1992). <\/p>\n

G\u00f3mez, M.J., \u00c1lvarez, X.A., Cacabelos, R. Dementia Mood Assessment Scale in elderly controls and in patients with depression and\/or cognitive impairment. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov., 1992. Anales Psiquiatr\u00eda 8(Supl. 1):102 (1992). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Serum growth hormone (GH) levels in psychiatric patients. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov., 1992. Anales Psiquiatr\u00eda, 8(Supl.1)106 (1992). <\/p>\n

Caama\u00f1o, J., Valle-lncl\u00e1n, F., Cacabelos, R. Blood flow velocity in multi-infarct dementia and Alzheimer\u2019s disease: Neuropsychological correlations. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov., 1992. Anales Psiquiatr\u00eda, 8(Supl.1):107-108 (1992). <\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Franco, A., G\u00f3mez, M.J., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F. Influence of CDP-Choline on cognitive parameters in Alzheimer\u2019s disease and multi-infarct dementia. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov., 1992. Anales Psiquiatr\u00eda, 8(Supl.1):108 (1992). <\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., Franco, A., \u00c1lvarez, X.A. Serum histamine and tumor necrosis factor (TNF) in Alzheimer\u2019s disease and multi-infarct dementia. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov. 1992. Anales Psiquiatr\u00eda, 8(Supl.1):108 (1992). <\/p>\n

Franco, A., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Serum interleukin-1p in control subjects and senile dementia. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov. 1992. Anales Psiquiatr\u00eda, 8(Supl.1):109 (1992).<\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Franco-Maside, A., Fern\u00e1ndez- Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F. Effect of CDP-Choline on cognition and immune function in Alzheimer\u2019s disease and multi-infarct dementia. Proc. 7th Meeting International Study Group on the Pharmacology of memory disorders associated with aging. Alzheimer\u2019s disease: Amyloid precursor proteins, signal transduction, and neural transplantation. Nitsch, R.M., Growdon, J.H., Corkin, S., Wurtman, R.J., Z\u00fcrich, Switzerland, Feb. 12-14; pp. 391-393 (1993). <\/p>\n

Cacabelos, R. Biomedical aspects of Alzheimer\u2019s disease: Introductory remarks. International Workshop on Alzheimer\u2019s disease: Progress for the next decade. Fundaci\u00f3n Ram\u00f3n Areces, March 22-23, 1993.<\/p>\n

Cacabelos, R. New trends for an etiopathogenic therapy in Alzheimer\u2019s disease. lnternational Workshop on Alzheimer\u2019s disease: Progress for the next decade. Fundaci\u00f3n Ram\u00f3n Areces. March 22-23, l993. <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Novo, B., Rettori, M.C., Garc\u00eda, M., Cacabelos, R. Effects of S-9977-2 on learning and behavior in rats with neurotoxic lesions in the nucleus basalis of Meynert (NBM). Recent advances in the treatment of neurodegenerative disorders and cognitive dysfunction. Collegium Internationale Neuro-Psychopharmacologicum (CINP) President\u2019s Workshop. Capri (Italy), May 1-3, 1993. pp. 125 (1993). <\/p>\n

G\u00f3mez, M.J., Cacabelos, R. Alzheimer\u2019s Disease Assessment Scale in control elderly subjects and in patients with Alzheimer\u2019s disease or multi-infarct dementia. Recent advances in the treatment of neurodegenerative disorders and cognitive dysfunction. CINP. President\u2019s Workshop. Capri (Italy), May 1-3, pp. 141 (1993). <\/p>\n

Franco-Maside, A., Caama\u00f1o, J., G\u00f3mez, M.J., \u00c1lvarez, A., Fern\u00e1ndez-Novoa, L., Novo, B., Cacabelos, R. CDP-Choline-induced brain mapping changes in patients with Alzheimer\u2019s disease. Recent advances in the treatment of neurodegenerative disorders and cognitive dysfunction. CINP. President\u2019s Workshop. Capri (Italy), May 1-3, pp. 154 (1993). <\/p>\n

Caama\u00f1o, J., Franco, A., G\u00f3mez, M.J., Novo, B., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Acute effects of CDP-Choline on middle cerebral artery blood flow velocities in Alzheimer\u2019s disease: A transcranial Doppler study. Recent advances in the treatment of neurodegenerative disorders and cognitive dysfunction. CINP. President\u2019s Workshop. Capri (Italy), May 1-3, pp. 155 (1993). <\/p>\n

Cacabelos, R, Perspectivas actuais do tratamento da demencia de Alzheimer. Demencias: Avan\u00e7os recentes. Actualiza\u00e7ao nos aspectos bioqu\u00edmicos, cl\u00ednicos e terap\u00e9uticos. Hospital de Universidade de Coimbra. Coimbra, Portugal, May 8, 1993. <\/p>\n

Cacabelos, R. Enfermedad de Alzheimer: Estrategias diagn\u00f3sticas y terap\u00e9uticas. VIII Congr. Soc. Castellano-leonesa Cantabra de Medicina Interna. Zamora, Mayo 14-15, 1993. Anales Medicina Interna, Extra II, Mayo, pp. 19 (1993). <\/p>\n

Cacabelos, R. Role of histamine and interleukin-1 in the neuroimmune dysregulation occurring in Alzheimer\u2019s disease. Eur. Histamine Res. Soc., Cologne, Germany, May 19-22, pp. 7 (1993). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of neurotoxic lesions in histaminergic neurons on psychomotor activity and learning. Eur. Histamine Res. Soc., Cologne, Germany, May 19-22, pp. 70 (1993). <\/p>\n

Fern\u00e1ndez-Novoa, L., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Changes in serum histamine and tumor necrosis factor (TNF) from patients with Alzheimer\u2019s disease and multi-infarct dementia. Eur. Histamine Res. Soc., Cologne, Germany, May 19- 22, pp. 89 (1993).<\/p>\n

Fern\u00e1ndez-Novoa, L., Franco, A., Lodeiro, C., \u00c1lvarez, X.A., Cacabelos, R. Effects of histamine and alpha-fluoromethylhistidine on brain tumor necrosis factor levels. Eur. Histamine Res. Soc., Cologne, Germany, May 19-22, pp. 90 (1993). <\/p>\n

Franco, A., Fern\u00e1ndez-Novoa, L., Lodeiro, C., \u00c1lvarez, X.A., Cacabelos, R. Effects of histamine and antihistaminics on the hippocampal levels of interleukin-1\uf062 in rats. Eur. Histamine Res. Soc., Cologne, Germany, May 19-22, pp. 91 (1993). <\/p>\n

Fern\u00e1ndez-Novoa, L., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Effects of neurotoxic lesions in histaminergic neurons on brain tumor necrosis factor. Eur. Histamine Res. Soc., Cologne, Germany, May 19-22, pp. P-86 (1993). <\/p>\n

Caama\u00f1o, J., Valle-lncl\u00e1n, F., Cacabelos, R. Blood flow velocity in multi-infarct dementia and Alzheimer\u2019s disease studied by transcranial Doppler ultrasonography. World Congr. Gerontology. XVth Congr. Intern. Assoc. Gerontology, Budapest, July 4-9, pp. 301 (1993). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Novo, B., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Age-dependent serum interleukin-1 beta levels in healthy control subjects. World Congr. Gerontology. XVth Congr. Intern. Assoc. Gerontology, Budapest, July 4-9, pp. 302 (1993). <\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., P\u00e9rez-Trull\u00e9n, J.M., Franco, A., \u00c1lvarez, X.A. Serum tumor necrosis factor (TNF) in Alzheimer\u2019s disease (AD) and multi-infarct dementia (MID). World Congr. Gerontology. XVth Congr. Intern. Assoc. Gerontology, Budapest, July 4-9, pp. 302 (1993). <\/p>\n

G\u00f3mez, M.J., \u00c1lvarez, X.A., Cacabelos, R. Dementia mood assessment scale in elderly controls and in patients with depression and\/or dementia. World Congr. Gerontology. XVth Congr. Intern. Assoc. Gerontology, Budapest, July 4-9, pp. 302 (1993). <\/p>\n

Cacabelos, R. Bases bioqu\u00edmicas del trastorno afectivo bipolar. XVII Reuni\u00f3n Nacional Soc. Esp. Psiquiat. Biol., Salamanca, Junio 16-19 (1993). <\/p>\n

Caama\u00f1o, J., Franco, A., G\u00f3mez, M.J., Novo, B., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Cerebrovascular effects of CDP-choline in patients with Alzheimer\u2019s disease: A transcranial Doppler study. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. <\/p>\n

G\u00f3mez, M.J., Cacabelos, R. Alzheimer\u2019s disease assessment scale in control elderly subjects and in patients with senile dementia. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. <\/p>\n

Franco-Maside, A., Caama\u00f1o, J., Cacabelos, R. Brain electrical activity mapping correlates with cerebral blood flow velocity in Alzheimer\u2019s disease. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. <\/p>\n

Cacabelos, R., Miller, D., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Franco-Maside, A., Nishimura, T., Pearson, J. Brain interleukin-1\uf062 in Alzheimer\u2019s disease and vascular dementia. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of Anapsos on psychomotor activity, passive avoidance behavior and brain interleukin-1\uf062 levels. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. <\/p>\n

\u00c1lvarez, X.A., Franco, A., Rettori, M.C., Polo, E., Garc\u00eda, M., Cacabelos, R. Effects of S9977-2 on behavior and brain interleukin-1\uf062 levels in an animal model of cognitive impairment. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. <\/p>\n

Caama\u00f1o, J., Franco, A., G\u00f3mez, M.J., Novo, B., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Cerebrovascular effects of CDP-choline in patients with Alzheimer\u2019s disease: Hemodynamic parameters measured by transcranial Doppler ultrasonography. 16th Ann. Meeting Eur. Neurosci. Assoc., Madrid, Sept. 18-21, pp. 88, 1993. <\/p>\n

Franco-Maside, A., Caama\u00f1o, J., Cacabelos, R. Brain electrical activity mapping correlates with cerebral blood flow velocity in Alzheimer\u2019s disease. 16th Ann. Meeting Eur. Neurosci. Assoc., Madrid, Sept. 18-21, pp. 89, 1993. <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Franco, A., Cacabelos, R. Influence of brain histamine on interleukin-1\uf062 production in the hypothalamus and hippocampus. 16th Ann. Meeting Eur. Neurosci. Assoc., Madrid, Sept. 18-21, pp. 169, 1993. <\/p>\n

Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Franco-Maside, A., Caama\u00f1o, J., Cacabelos, R. CDP-choline-induced changes in blood histamine in patients with Alzheimer\u2019s disease. 16th Ann. Meeting Eur. Neurosci. Assoc., Madrid, Sep. 18-21, pp. l l8, 1993. <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Rettori, M.C., Garc\u00eda, M., Cacabelos, R. Time- and dose-dependent effects of S9977 on behavior and brain interleukin-1\uf062. First Int. Congr. on Hormones, Brain and Neuropharmacology, Rhodes, Sept. 13-17, 1993. Neuropsychopharmacology 9\/2S:78S (1993). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of Anapsos on behavior and brain neuroimmune factors. First Int. Congr. on Hormones, Brain and Neuropsychopharmacology, Rhodes, Sept. 13-17, 1993. Neuropsychopharmacology, 9\/2S:164S (1993). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of neurotoxic lesions in histaminergic neurons on behavior and brain cytokines. First Int. Congr. on Hormones, Brain and Neuropsychopharmacology, Rhodes, Sept. 13-17, 1993. Neuropsychopharmacology 9\/2S:164S (1993). <\/p>\n

Cacabelos, R. Presente y futuro de la investigaci\u00f3n sobre la enfermedad de Alzheimer. III Congr. Soc. Gallega Gerontolog\u00eda y Geriatr\u00eda, La Coru\u00f1a, Sep. 23-25, 1993. <\/p>\n

Cacabelos, R. Enfermedad de Alzheimer: Perspectivas para una d\u00e9cada. Primeres Jornades Geri\u00e0triques, Malatia d\u00b4Alzheimer, Universitat Ramon Llull, Barcelona, Oct. 22-23, 1993. <\/p>\n

Cacabelos, R. Neurobiolog\u00eda y gen\u00e9tica molecular de la enfermedad de Alzheimer. Simposium internacional: Perspectivas actuales de la gen\u00e9tica humana. Fundaci\u00f3n Ram\u00f3n Areces, Madrid, Oct. 25-27, 1993. <\/p>\n

Franco-Maside, A., Caama\u00f1o, J., G\u00f3mez, M.J., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Novo, B., Cacabelos, R. CDP-choline-induced brain mapping changes in patients with Alzheimer\u2019s disease. 6th Congr. ECNP, Budapest, Oct. l l-l4, 1993. <\/p>\n

Caama\u00f1o, J., Franco, A., G\u00f3mez, M.J., Novo, B., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Acute effects of CDP-choline on middle cerebral artery blood flow velocities in Alzheimer\u2019s disease: A transcranial Doppler study. 6th Congr. ECNP, Budapest, Oct. 11-l4, 1993. <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Age-related changes in serum interleukin-1\uf062 and tumor necrosis factor-alpha levels in healthy control subjects. 6th Congr. ECNP, Budapest, Oct. 11-14, 1993. <\/p>\n

\u00c1lvarez, X.A., Franco, A., Kamoun, A., Polo, E., Cacabelos, R., Rettori, M.C. S9977-2 reduces learning impairment and brain interleukin-1\uf062 overproduction in rats with neurotoxic lesions in the nucleus basalis of Meynert. 6th Congr. ECNP, Budapest, Oct. 11-14, 1993. <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of Anapsos on behavior and brain neuroimmune function. 6th Congr. ECNP, Budapest, Oct. 11-14, 1993. <\/p>\n

Cacabelos, R. Tratamento farmacologico da Doen\u00e7a de Alzheimer: Bases moleculares. Psiquiatr\u00eda: das suas raices aos seus elos de liga\u00e7ao. Figueira da Foz, Oct. 28-30, 1993. <\/p>\n

Cacabelos, R. Envejecimiento y demencia en el marco de la atenci\u00f3n primaria. Simposium sat\u00e9lite Bayer. Congr. Soc. Esp. Med. Fam. Comunitaria. La Coru\u00f1a, Nov. 11-13, 1993. <\/p>\n

Cacabelos, R. Nuevas alternativas terap\u00e9uticas en las demencias. III Symposium Taller Internacional. Psiquiatr\u00eda, Esquizofrenia y Demencias. A\u00f1o 2000. Tenerife, 28-30 Abril, 1994. <\/p>\n

Cacabelos, R. Psicof\u00e1rmacos convencionales en psicogeriatr\u00eda. III Symposium Taller Internacional. Psiquiatr\u00eda, Esquizofrenia y Demencias. A\u00f1o 2000. Tenerife 28-30 Abril, 1994. <\/p>\n

Cacabelos, R. New strategies for Alzheimer\u2019s disease treatment: Pleiotropic drugs and multifactorial intervention. Third International Springfield Symposium on Advances in Alzheimer therapy. May 11-15, Springfield, Illinois, pp. 103 (1994). <\/p>\n

Caama\u00f1o, J., G\u00f3mez, M.J., Franco, A., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Novo, B., Vinagre, D., Cacabelos, R. Cerebrovascular and cognitive effects of CDP-choline in patients with Alzheimer\u2019s disease. Third International Springfield Symposium on Advances in Alzheimer Therapy. May 11-15, Springfield, Illinois, pp. 119 (1994). <\/p>\n

Franco-Maside, A., Caama\u00f1o, J., G\u00f3mez, M.J., Vinagre, D., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Novo, B., Zas, R., Cacabelos, R. Effects of CDP-choline in brain electrical activity mapping and cerebral blood flow velocities in Alzheimer\u2019s disease. Third International Springfield Symposium on Advances in Alzheimer Therapy. May 11-l5, Springfield, Illinois, pp. 120 (1994). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Caama\u00f1o, J., Novo, B., Diaz, J., Sempere, J.M., Cacabelos, R. Effects of Anapsos on behavior and brain neuroimmune factors in rats with neurotoxic lesions in the nucleus basalis of Meynert. Third International Springfield Symposium on Advances in Alzheimer Therapy. May 11-l5, Springfield, Illinois, pp. 122 (1994). <\/p>\n

Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Zas, R., G\u00f3mez, M.J., Vinagre, D., Sada. G., Cacabelos, R. Effects of Polipodium leucotomos (Difur) on behavior and the hippocampal levels of interleukin-1\uf062, histamine and tumor necrosis factor in nbM-lesioned rats. Third International Springfield Symposium on Advances in Alzheimer Therapy. May 11-15, Springfield, Illinois, pp. 122 (1994). <\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A. Brain histamine in aging and senile dementia. XXIIIrd Annual Meeting European Histamine Res. Soc., Budapest, May 18-21, pp. 4 (1994). <\/p>\n

Fern\u00e1ndez-Novoa, L., Zas, R., Deslandes, A., Polo, E., \u00c1lvarez, X.A., Cacabelos, R. Time- and dose-dependent changes induced by S-9977-2 in brain histamine. XXIIIrd Ann. Meet. Eur. Histamine Res. Soc., Budapest, May 18-21, 1994. <\/p>\n

Cacabelos, R., Franco-Maside, A., Caama\u00f1o, J., Zas, R., Novo, B., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A. CDP-choline reduces blood histamine levels in Alzheimer\u2019s disease patients. XXIIIrd Ann. Meet. Eur. Histamine Res. Soc., Budapest, May 18-21, 1994. <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Cacabelos, R. Effects of neurotoxic lesions in the nucleus basalis of Meynert on brain histamine. XXIIIrd Ann. Meet Eur. Histamine Res. Soc., Budapest, May 18-21, 1994. <\/p>\n

Caama\u00f1o, J., Franco-Maside, A., Cacabelos, R. Blood histamine correlates with cerebrovascular parameters and quantitative EEG in Alzheimer\u2019s disease. XXIIIrd Ann. Meet. Eur. Histamine Res. Soc., Budapest, May 18-21, 1994. <\/p>\n

Cacabelos, R. Enfermedad de Alzheimer. V Symposium Internacional. Centro Neuropsiqui\u00e1trico \u201cSagrado Coraz\u00f3n\u201d. Martorell, Barcelona, 16-18 Junio, 1994. <\/p>\n

Cacabelos, R., Sempere, J.M. Factores etiopatog\u00e9nicos en la enfermedad de Alzheimer. Funci\u00f3n inmune. Jornada de Formaci\u00f3n Biom\u00e9dica. Introducci\u00f3n al tratamiento neuroinmune y neurotr\u00f3fico en la enfermedad de Alzheimer. Colegio M\u00e9dicos, Alicante, 10 Junio, 1994. <\/p>\n

Cacabelos, R. Estrategias terap\u00e9uticas en la enfermedad de Alzheimer. Jornada de Formaci\u00f3n Biom\u00e9dica. Introducci\u00f3n al tratamiento neuroinmune y neurotr\u00f3fico en la enfermedad de Alzheimer. Colegio M\u00e9dicos, Alicante, 10 Junio, 1994. <\/p>\n

Cacabelos, R. Biological markers and the cholinergic hypothesis in Alzheimer\u2019s disease. Putative mechanisms of action of Tacrine. Advances in the management of Alzheimer\u2019s disease. The role of Tacrine. Satellite Symposium. Fourth Meet. Eur. Neurol. Soc., Barcelona, 29 June, 1994. <\/p>\n

Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Franco-Maside, A., \u00c1lvarez, X.A., Cacabelos, R. Blood histamine correlates with cerebrovascular parameters and brain electrical activity mapping in Alzheimer\u2019s disease. XIXth CINP, Washington DC, June 27-July 1, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, pp. 215S (1994). <\/p>\n

Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X,A., Cacabelos, R. CDP-choline-induced blood histamine changes in Alzheimer\u2019s disease. XIXth CINP, Washingon DC, June 27-July l, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, pp. 131S (1994). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Zas, R., Cacabelos, R. Effects of Anapsos on behavior and brain interleukin-1\uf062. XIXth CINP, Washingon DC, June 27-July 1, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, pp. 38S (1994). <\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., Zas, R., Deslandes, A., Garc\u00eda, M., \u00c1lvarez, X.A. Time- and dose-dependent effects of S-9977-2 on brain histamine. XIXth CINP, Washingon DC, June 27- July 1, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, 147S (1994). <\/p>\n

Franco-Maside, A., Caama\u00f1o, J., G\u00f3mez, M.J., Cacabelos, R. Brain mapping activity and mental performance after chronic treatment with CDP-choline in Alzheimer\u2019s disease. XIX CINP, Washingon DC, June 27-July l, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, 216S (1994). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Zas, R., Kamoun, A., Polo, E., Garc\u00eda, M., Cacabelos, R. Behavioral and neuroimmune effects of S-9977-2. XIXth CINP, Washingon DC, June 27-July l, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, 39S (1994). <\/p>\n

Cacabelos, R. Therapy for two symptoms of Alzheimer\u2019s disease. Roundtable: Treating Alzheimer\u2019s disease: present potential and future prospects. University of Minnesota. Accreditation Council for Continuing Medical Education. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 20-August 3, 1994. <\/p>\n

\u00c1lvarez, X.A., Franco-Maside, A., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., G\u00f3mez, M.J., Novo, B., Zas, R., Cacabelos, R. Blood levels of histamine, interleukin-1\uf062 and tumor necrosis factor in Alzheimer\u2019s disease. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 20-August 3, 1994. Neurobiol. Aging, 15(Suppl.1):S93 (1994). <\/p>\n

Caama\u00f1o, J., G\u00f3mez, M.J., Vinagre, D., Franco, A., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Zas, R., Novo, B., Cacabelos, R. Hemodynamic parameters of the middle cerebral artery in cerebrovascular disorders and senile dementia: A transcranial Doppler study. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 29-August 3, 1994. Neurobiol. Aging, 15 (Suppl.1):S96 (1994). <\/p>\n

Franco-Maside, A., Caama\u00f1o, J., Vinagre, D., G\u00f3mez. M.J., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Brain electrical activity mapping correlates with cerebral blood flow velocity in Alzheimer\u2019s disease. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 29-August 3, 1994. Neurobiol. Aging, 15(Suppl.1):S98 (1994).<\/p>\n

G\u00f3mez, M.J., Caama\u00f1o, J., Vinagre, D., Franco, A., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X., Zas, R., Novo, B., Cacabelos, R. Cognitive and non-cognitive profiles in cerebrovascular disorders and senile dementia: A neuropsychological study. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 29-August 3, 1994. Neurobiol. Aging, 15(Suppl.1);S106 (1994) <\/p>\n

Fern\u00e1ndez-Novoa, L., Franco-Maside, A., \u00c1lvarez, X.A., Caama\u00f1o, J., G\u00f3mez, M.J., Zas, R., Cacabelos, R. Histamine, interleukin- IO and tumor necrosis factor correlate with brain electrical activity mapping in Alzheimer\u2019s disease. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 29-August 3, 1994. Neurobiol. Aging, 15 (Suppl.l):S l21 (1994). <\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L. Brain tumor necrosis factor alpha (TNF) in Alzheimer\u2019s disease (AD). 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 29-August 3, 1994. Neurobiol. Aging, 15(Suppl.1):S152 (1994). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Vinagre, D., G\u00f3mez, M.J., Sada, G., Cacabelos, R. Effects of polipodium leucotomos (Difur) on behavioral parameters and brain neuroimmune factors in nbm-lesioned rats. ECNP, Jerusalem, Oct. 16-21, 1994. <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Franco, A., Kamoun, A., Deslandes, A., Polo, E., Gorostiaga, C., Cacabelos, R. S-9977-2 normalizes behavior and brain interleukin-1\uf062 levels in rats with lesions in the nucleus basalis of Meynert. ECNP, Jerusalem, Oct. 16-21, 1994. <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Caama\u00f1o, J., Novo, B., D\u00edaz, J., Sempere, J.M., Cacabelos, R. Behavioral and neuroimmune effects of anapsos in cognitively-impaired rats. ECNP. Jerusalem, Oct. 16-21, 1994. <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Cacabelos, R. Effects of scopolamine on behavior and brain neuroimmune factors in rats. 17th Ann. Meet. Eur. Neurosci. Assoc., Vienna, 4-8 Sept., pp. 95 (1994). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Vinagre, D., Sada, G., Cacabelos, R. Effects of polipodium leucotomos (Difur) on behavior and brain neuroimmune factors in nbM-lesioned rats. 17th Ann. Meet. Eur. Neurosci. Assoc., Vienna, 4-8 Sept., pp. 99 (1994). <\/p>\n

Caama\u00f1o, J., G\u00f3mez, M.J., Vinagre, D., Franco, A., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Zas, R., Novo, B., Cacabelos, R. Hemodynamic parameters of the middle cerebral artery in cerebrovascular disorders and senile dementia. 17th Ann. Meet. Eur. Neurosci. Assoc., Vienna, 4-8 Sept., pp. l l0 (1994). <\/p>\n

Vinagre, D., Franco-Maside, A., Caama\u00f1o, J., G\u00f3mez, M.J., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Novo, B., Zas, R., Cacabelos, R. Brain electrical activity mapping in senile dementia and cerebrovascular disorders. 17th Ann. Meet. Eur. Neurosci. Assoc., Vienna, 4-8 Sept., pp. 110 (1994). <\/p>\n

Cacabelos, R., Franco, A., Fern\u00e1ndez-Novoa, L., Zas, R., D\u00edaz, J., Sempere, J.M., \u00c1lvarez, X.A. Behavioral and neuroimmune effects of Anapsos in intact and nbM-lesioned rats. IBC\u2019s Third Annual Alzheimer\u2019s Disease. Advances in Understanding and treatment. Philadelphia, 22-23 Sept. (1994).<\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., Zas, R., Franco-Maside, A., Deslandes, A., Garc\u00eda, M., Kamoun, A., \u00c1lvarez, X.A. Effects of S-9977-2 on behavior and brain neuroimmune factors in rats. IBC\u2019s Third Annual Alzheimer\u2019s Disease. Advances in Understanding and Treatment. Philadelphia, 22-23 Sept. (1994). <\/p>\n

Cacabelos, R., Caama\u00f1o, J., G\u00f3mez, M.J., \u00c1lvarez, X.A., Novo, B., Zas, R., Garc\u00eda, M., Polo, E., Malbezin, M., Neuman, E., Guez, D. Effects of S-I2024-2 on cognition, brain mapping and cerebrovascular parameters in Alzheimer\u2019s disease. IBC\u2019s Third Annual Alzheimer\u2019s Disease. Advances in Understanding and Treatment. Philadelphia, 22-23 Sept. (1994). <\/p>\n

Cacabelos, R. Bases etiopatog\u00e9nicas de la enfermedad de Alzheimer. II Symposium Hispano- Americano. Avances en Psiquiatr\u00eda. Facultad de Medicina. Universidad de Salamanca. Salamanca, 28-30 Marzo, 1995. <\/p>\n

Cacabelos, R. Enfermedad de Alzheimer. Mesa Redonda. V Congreso de la Comunidad Valenciana para M\u00e9dicos Rurales y Generalistas. Benicasim, 27-29 Abril, 1995. <\/p>\n

Cacabelos, R. Enfermedad de Alzheimer. Predictores de un tratamiento etiopatog\u00e9nico. IV Reuni\u00f3n de la Soc. de Psiquiatr\u00eda de la Comunidad Valenciana. Hotel Castilla, Alicante 28-29 Abril, 1995, <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Franco, A., Zas, R., Lagares, R., Sastre, I., Beyer, K., Lao, J.I., Miguel-Hidalgo, J.J., Garc\u00eda, M., Guez, D., Cacabelos, R. Effects of S-9977-2 on learning and brain vasopressin in rats. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July, 1995. Alzheimer\u2019s Res., 1(Suppl. 1):120P (1995) <\/p>\n

Miguel-Hidalgo, J.J., Maneiro, E., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Plastic effects of 1-28 amyloid \uf062-protein fragment deposits in the hippocampus with and without CDP-choline treatment. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1(Suppl. 1) :28 (1995).<\/p>\n

Beyer, K., Lao, J.l., \u00c1lvarez, X.A., Franco, A., Cacabelos, R. Alzheimer\u2019s disease genotyping in families at risk. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1(Suppl. 1):47 (1995). <\/p>\n

Fern\u00e1ndez-Novoa, L., Franco-Maside, A., \u00c1lvarez, X.A., Maneiro, E., Lagares, R., Miguel-Hidalgo, J.J., Beyer, K., Bullido, M.J., Valdivieso, F., Caama\u00f1o, J., G\u00f3mez, M.J., Vinagre, D., Cacabelos, R. APO-E genotyped patients with senile dementia: Correlations between plasma interleukin-1\uf062 and whole blood histamine. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1(Suppl. 1):50 (1995). <\/p>\n

Cacabelos, R., Franco, A., Bullido, M.J., Recuero, M., Sastre, L., Zas, R., \u00c1lvarez, X.A., Lao, J.I., Beyer, K., Valdivieso, F. APO-E genotypes in Alzheimer\u2019s disease and vascular dementia. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1(Suppl. 1):50 (1995). <\/p>\n

Cacabelos, R., Vigo-Pelfrey, C., Franco-Maside, A., Lao, J.l., Beyer, K., Zas, R., \u00c1lvarez, X.A. Serum \uf062-amyloid levels in demented patients with different APO-E genotypes. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1 (Suppl. 1):51 (1995).<\/p>\n

\u00c1lvarez, X.A., Zas, R., Lagares, R., Franco-Maside, A., Fern\u00e1ndez-Novoa, L., D\u00edaz, J., Cacabelos. R. Effects of the chronic administration of Anapsos on behavior in old mice. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1(Suppl. 1):53 (1995). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Franco, A., Zas, R., Lagares, R., Beyer, K., Lao, J.I., Miguel- Hidalgo, J.J., Garc\u00eda, M., Guez, D., Cacabelos, R. Effects of S-9977-2 on learning and brain vasopressin levels in rats. Fourth IBRO World Congr. Neurosci., Kyoto, Japan, 9-14 July, pp. 376 (1995).<\/p>\n

Miguel-Hidalgo, J.J., Lagares, R., Franco, A., Beyer, K., Lao, J.I., \u00c1lvarez, X.A., Cacabelos, R. Detection of bilateral neuronal degeneration after multiple lesions into the rat brain. Fourth IBRO World Congr. Neurosci., Kyoto, Japan, 9-14 July, pp. 246 (1995). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Franco, A., Zas, R., Lagares, R., Beyer, K., Lao, J.I., Miguel-Hidalgo, J.J., Garc\u00eda, M., Guez, D., Cacabelos, R. Effects of S-12024-2 on brain vasopressin levels in rats. Fourth IBRO World Congr. Neurosci., Kyoto, Japan, 9-14 July, pp. 122 (1995). <\/p>\n

Cacabelos, R. Demencia. Etiopatogenia. V Congr. Castellano-Leon\u00e9s de Geriatr\u00eda y Gerontolog\u00eda. Benavente, 29-30 Sept., 1995. <\/p>\n

Cacabelos, R. Senile cognitive decline: Characterization of genotypic-phenotypic correlations in Alzheimer\u2019s disease. Congr. Spanish Soc. Physiological Sciences & The Physiological Society, Salamanca, 2-5 Oct., 1995. <\/p>\n

Cacabelos, R. CDP-Choline. Clinical experience. XI Conferencia Internacional. Alzheimer\u2019s Disease International. Buenos Aires, 12-15 Sept., 1995. <\/p>\n

Cacabelos, R., Franco-Maside, A., Bullido, M.J., Recuero, M., Sastre, I., Zas, R., \u00c1lvarez, X.A., Lao, J.I., Beyer, K., Valdivieso, F. Age- and sex-related APO-E genotypes in Alzheimer\u2019s disease and vascular dementia. 1995 World Congress on Psychiatric Genetics. Psychiatric Genetics 5:S70 (1995). <\/p>\n

Beyer, K., Lao, J.I., \u00c1lvarez, X.A., Cacabelos, R. Rapid molecular detection of the fragile X gene trinucleotide repeat. 1995 World Congress on Psychiatric Genetics. Psychiatric Genetics 5:S85 (1995).<\/p>\n

\u00c1lvarez, X.A., Zas, R., Lagares, R., Franco-Maside, A., Fern\u00e1ndez-Novoa, L., D\u00edaz, J., Cacabelos, R. Chronic Anapsos administration improves psychomotor functioning in old mice. 7th IPA Congress, Sydney, 29 Oct.-3 Nov., 1995.<\/p>\n

Miguel-Hidalgo, J.J., Maneiro, E., \u00c1lvarez, X.A., Lagares, R., Franco, A., Fern\u00e1ndez-Novoa, L., Lao, J.I., Beyer, K., Cacabelos, R. Effects of 1-28 A\uf062P deposits in the hippocampus with and without CDP-choline treatment. 7th IPA Congress, Sydney, 29 Oct.-3 Nov., 1995. <\/p>\n

Beyer, K., Lao-Villad\u00f3niga, J.I., Zas, R., Franco-Maside, A., Lagares, R., Miguel-Hidalgo, J.J., Maneiro, E., \u00c1lvarez, X.A., Cacabelos, R. A rapid molecular characterization of Alzheimer\u2019s disease. 7th IPA Congress, Sydney, 29 Oct.-3 Nov., 1995. <\/p>\n

Cacabelos, R., Franco, A., Bullido, M.J., Recuero, M., Sastres, I., Zas, R., \u00c1lvarez, X.A., Lao, J.I., Beyer, K., Valdivieso, F. APO-E genotypes in Alzheimer\u2019s disease and vascular dementia. 7th IPA Congress, Sydney, 29 Oct.-3 Nov., 1995. <\/p>\n

Vigo-Pelfrey, C., \u00c1lvarez, X.A., Franco-Maside, A., Cacabelos, R. Serum \uf062-Amyloid levels in Alzheimer\u2019s disease and vascular dementia. 7th IPA Congress, Sydney, 29 Oct.-3 Nov., 1995. <\/p>\n

Cacabelos, R. Pharmacological treatment of memory disorders. International Conference in Neuropsychiatry. Restoring Brain Function. A Multidisciplinary Approach. The University of Illinois, Chicago, 1-2 Dec., 1995. <\/p>\n

Beyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., Franco-Maside, A., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R. Allelic frequency of ApoE in the Spanish population. HGM\u00b496. HUGO\u2019s Human Genome Meeting, Heidelberg, March 22-24, pp. 11 (1996). <\/p>\n

Lao, J.I., Beyer, K., Fern\u00e1ndez-Novoa, L., Franco-Maside, A., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R. Cytogenetic findings in Alzheimer\u2019s disease. HGM\u201996. HUGO\u2019s Human Genome Meeting, Heidelberg, 22-24 March, pp. 57 (1996). <\/p>\n

Allain, H., Guez, D., Cacabelos, R., Derouesn\u00e9, C., Jolles, J., Lenzi, G.L., Levy, R., Bruno, J., Neuman, E., Lepagnol, J. Safety and efficacy of S-12024 in patients with mild to moderate Alzheimer\u2019s disease. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 74 (1996). <\/p>\n

Cacabelos, R., Lagares, R., Fern\u00e1ndez-Novoa, L., Franco-Maside, A., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A. Anapsos: New therapeutic strategies for neurodegeneration and brain aging with natural neuroimmunotrophic factors. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 83 (1996). <\/p>\n

Cacabelos, R., Vinagre, D., Caama\u00f1o, J., Lao, J.I., Beyer, K., \u00c1lvarez, X.A. Brain mapping and transcranial Doppler ultrasonography in Alzheimer disease drug monitoring. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 95 (1996). <\/p>\n

\u00c1lvarez, X.A., Miguel-Hidalgo, J.J., Lagares, R., Franco, A., Fern\u00e1ndez-Novoa, L., Lao, J.I., D\u00edaz, J., Sempere, J.M., Cacabelos, R. Neuroprotective activity of anapsos in rats with hippocampal degeneration. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 130 (1996). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez, L., Beyer, K., Garc\u00eda, M., Polo, E., Desche, P., Guez, D., Cacabelos, R. Behavioral and neurochemical effects of S12024 in rats with implants of \uf062-amyloid into the hippocampus. Fourth lnternational Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 130 (1996) <\/p>\n

\u00c1lvarez, X.A., Zas, R., Garc\u00eda, M., Polo, E., Desche, P., Guez, D., Cacabelos, R. Comparative effects of S9977-2 vs Tacrine in learning and locomotion. Fourth lnternational Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 131 (1996). <\/p>\n

\u00c1lvarez, X.A., Lagares, R., Franco, A., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., Beyer, K., Cacabelos, R. Effects of CDP-choline in rats with brain neurotoxic lesions. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 131 (1996). <\/p>\n

Beyer, K., Lao, J.I., Maneiro, E., Cacabelos, R, Alzheimer soluble factor (ASF): A potential peripheral marker for genetic Alzheimer disease. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 135 (1996). <\/p>\n

Cacabelos, R., Caama\u00f1o, J., G\u00f3mez, M.J., Franco-Maside, A., Vinagre, D., Novo, B., Zas, R., \u00c1lvarez, X.A., Polo, E., Garc\u00eda, M., Neuman, E., Guez, D. S-12024-2: A double-blind randomized placebo-controlled study in patients with Alzheimer disease. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 138 (1996). <\/p>\n

Fern\u00e1ndez-Novoa, L., Franco-Maside, A., \u00c1lvarez, X.A., Vecino, B., D\u00edaz, J., Sempere, J.M., Cacabelos, R. Effects of anapsos on the activity of superoxide dismutase (SOD) in an animal model of neurodegeneration. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 143 (1996). <\/p>\n

Fern\u00e1ndez-Novoa, L., Vinagre, D., Franco-Maside, A., Caama\u00f1o, J., \u00c1lvarez, X.A., Cacabelos, R. Effects of famotidine on the levels of blood histamine in healthy subjects: Correlation studies with brain electrical activity mapping. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 143 (1996). <\/p>\n

Lao, J.I., Beyer, K., Cacabelos, R. Senile dementia-associated FOS gene mutation in the Spanish population. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 156 (1996). <\/p>\n

Maneiro, E., Lao, J.I., Beyer, K., Cacabelos, R. Microglia activation by an AD-associated 19kDa soluble factor. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 160 (1996). <\/p>\n

Winblad, B., Ravizza, L., Rossor, M., Cacabelos, R. Research priorities in Alzheimer disease treatment- An international perspective. A European response. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 16 (1996). <\/p>\n

Beyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R. Allelic frequency of ApoE in the Spanish population. The Lancet Conference 1996. The challenge of the dementias, Edinburgh, April 25-26, pp. 38 (1996). <\/p>\n

Cacabelos, R. Variaciones endocrinol\u00f3gicas en los trastornos ps\u00edquicos del anciano. XXI Congr. Nac. Soc. Esp. Geriatr\u00eda y Gerontolog\u00eda. V Reun. Soc. Castellano-Leonesa, Salamanca, Junio 5-8, 1996.<\/p>\n

Cacabelos, R. Etiopatogenia y prospecciones terap\u00e9uticas de la enfermedad de Alzheimer. Actualidad cient\u00edfica y sociosanitaria de la enfermedad de Alzheimer. Fundaci\u00f3n Ram\u00f3n Areces, Madrid, Junio 6, 1996. <\/p>\n

Cacabelos, R. Funci\u00f3n neuroinmunol\u00f3gica y endocrina en trastornos neurogeri\u00e1tricos. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31: Supl. I (1996). <\/p>\n

Sellers, A., Rodr\u00edguez, B., Cacabelos, R., Caama\u00f1o, J.M. Evaluaci\u00f3n psicom\u00e9trica de los trastornos del sue\u00f1o en la demencia senil. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31:Supl. l (1996). <\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., Caama\u00f1o, J., Zas, R., G\u00f3mez, M.J., \u00c1lvarez, X.A., Cacabelos, R. Hemodin\u00e1mica cerebral y niveles de histamina en enfermedad de Alzheimer y demencia vascular. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31:Supl. l (1996). <\/p>\n

Beyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J., \u00c1lvarez, X.A., Cacabelos, R. La frecuencia al\u00e9lica del ApoE en la poblaci\u00f3n gallega. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31:Supl. I (1996). <\/p>\n

Maneiro, E., Cacabelos, R. Modificaci\u00f3n de la microgl\u00eda por un factor soluble del suero de pacientes con enfermedad de Alzheimer. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31:Supl. I (1996). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Lagares, R., Franco, A., Beyer, K., Maneiro, E., Cacabelos, R. Efectos de anapsos sobre funci\u00f3n cerebral en ratones viejos. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31: Supl. I (1996). <\/p>\n

\u00c1lvarez, X.A., Miguel-Hidalgo, J.J., Lagares, R., Franco, A., Fern\u00e1ndez-Novoa, L., Beyer, K., Lao, J.l., Vecino, B., D\u00edaz, J., Sempere, J.M., Cacabelos, R. Protective effects of anapsos in rats with hippocampal neurodegeneration. XXth CINP Congress, Melbourne, June 23-27, 1996. Eur. Neuropharmacol., 6(Suppl. 3):75 (1996), <\/p>\n

Fern\u00e1ndez-Novoa, L., Franco-Maside, A., \u00c1lvarez, X.A., Vecino, B., D\u00edaz, J., Sempere, J,M., Cacabelos, R. Effects of anapsos on the activity of SOD in an animal model of neurodegeneration. XXth CINP Congress, Melbourne, June 23-27, 1996. Eur. Neuropharmacol., 6 (Supp1.3):193 (1996).<\/p>\n

Franco-Maside, A., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Vecino, B., D\u00edaz, J., Sempere, J.M., Cacabelos, R. Effects of anapsos on brain histamine and 1L-1\uf062 levels in an animal model of neurodegeneration. XXth CINP Congress, Melbourne, June 23-27, l996. Eur. Neuropharmacol., 6 (Suppl.3):193 (1996). <\/p>\n

\u00c1lvarez, X.A., Zas, R., Lagares, R., Franco, A., Fern\u00e1ndez-Novoa, L., D\u00edaz, J., Sempere, J.M., Cacabelos, R. Effects of anapsos on longevity, behavior and brain neurochemistry in mice. XXth CINP Congress, Melbourne, June 23-27, 1996. Eur. Neuropharmacol., 6(Suppl.3):193 (1996). <\/p>\n

Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Lagares, R., Franco, A., Fern\u00e1ndez. L., Cacabelos, R. Brain neurotoxic lesions in rats: Study of the neuroprotective effects of CDP-choline. XXth CINP Congress, Melbourne, June 23-27, 1996. Eur. Neuropharmacol., 6(Suppl.3): 193-194 (1996). <\/p>\n

\u00c1lvarez, X.A., Zas, R., Garc\u00eda, M., Polo, E., Guez, D., Cacabelos, R. Comparative effects of S- 9977-2 vs Tacrine on passive avoidance learning. XXth CINP Congress, Melbourne, June 23-27, 1996. Eur. Neuropharmacol., 6(Supp1.3):189-190 (1996). <\/p>\n

Maneiro, E., Lao, J.l., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R. Microglia activation by an AD-associated 19kDa soluble factor. Neurobiol. Aging, 17:S22 (1996). <\/p>\n

\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., Garc\u00eda, M., Polo, E., Desche, P., Cacabelos, R. Neuroprotective effects of S12024 in rats with implants of \uf062-amyloid into the hippocampus. Neurobiol. Aging, 17:S28-29 (1996). <\/p>\n

Cacabelos, R. Behavioral changes and biological markers associated with different genotypes in Alzheimer\u2019s disease. Neurobiol. Aging, 17:S47 (1996). <\/p>\n

Beyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., Vecino, B., \u00c1lvarez, X.A., Cacabelos, R. A molecular genetic approach to Alzheimer\u2019s disease from different genomic sites in the Spanish population. Neurobiol. Aging, 17:S60 (1996). <\/p>\n

Lao, J.I., Beyer, K., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., Vecino, B., \u00c1lvarez, X.A., Cacabelos, R. Cytogenetic signs of genomic instability in Alzheimer\u2019s disease. Neurobiol. Aging, 17:S62-63 (1996). <\/p>\n

Miguel-Hidalgo, J.J., Cacabelos, R. Subpopulations of rat Congo Red-staining neurons display distinct morphological features and altered distribution of \uf062-amyloid precursor protein immunoreactivity. Neurobiol. Aging, 17:S67 (1996). <\/p>\n

Lagares, R., \u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Beyer, K., Lao, J.I., Cacabelos, R. Behavioral deficits induced by stereotaxic \uf062-amyloid implants into the rat hippocampus. Neurobiol. Aging, 17:S68 (1996). <\/p>\n

Cacabelos, R., Maneiro, E., Lagares, R., Lao, J.I., Beyer, K., Miguel-Hidalgo, J.J., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A. Neuroimmunotrophic strategies in neurodegeneration and Alzheimer\u2019s disease. Neurobiol. Aging, 17:S139-140 (1996).<\/p>\n

Miguel-Hidalgo, J.J., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Franco, A., Cacabelos, R. Characterization of a model of neuronal degeneration in the gyrus dentatus of the rat: Neuroprotective effects of anapsos. Neurobiol. Aging, 17:S140 (1996). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Vinagre, D., G\u00f3mez, M.J., Cacabelos, R. Effects of\u00b4 anapsos on brain function: Preclinical and clinical neuropharmacological studies. Neurobiol. Aging, 17:S140-141 (1996). <\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., Caama\u00f1o, J., Zas, R., G\u00f3mez, M.J., \u00c1lvarez, X.A., Cacabelos, R. Histamine and brain hemodynamics in Alzheimer disease and vascular dementia patients according to global deterioration scale staging. Neurobiol. Aging, 17:S184 (1996). <\/p>\n

Cacabelos, R. Novel therapeutic strategies in Alzheimer\u2019s disease. X World Congress of Psychiatry, Madrid, August 23-28, pp. 120 (1996). <\/p>\n

Lao, J.I., Beyer, K., \u00c1lvarez, X.A., Cacabelos, R. Apo-E allelic frequency analysis in psychiatric disorders. X World Congress of Psychiatry, Madrid, August 23-28, pp. 195 (1996). <\/p>\n

Beyer, K., Lao, J.I., \u00c1lvarez, X.A., Cacabelos, R. Rapid molecular detection of the fragile X gene trinucleotide repeat. X World Congress of Psychiatry, Madrid, August 23-28, pp. 197 (1996). <\/p>\n

Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., D\u00edaz, J., Sempere, J.M., Cacabelos, R. Anapsos exerts neuroprotective effects in an animal model of neurodegeneration. X World Congress of Psychiatry, Madrid, August 23-28, pp. 211 (1996). <\/p>\n

Cacabelos, R., Vinagre, D., Caama\u00f1o, J., Lao, J.I., Beyer, K., \u00c1lvarez, X.A. Brain mapping and transcranial Doppler ultrasonography in Alzheimer\u2019s disease drug monitoring. X World Congress of Psychiatry, Madrid, August 23-28, pp. 212 (1996). <\/p>\n

Cacabelos, R., Maneiro, E., Beyer, K., Lao, J.l., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A. Effects of Alzheimer Apo-E-related ASF in microglia cell culture. X World Congress of Psychiatry, Madrid, August 23-28, pp. 213 (1996). <\/p>\n

Miguel-Hidalgo, J.J., Vecino, B., Fern\u00e1ndez-Novoa, L., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Neuroprotection by S-12024 in a model of neuronal degeneration in the rat hippocampus. X World Congress of Psychiatry, Madrid, August 23-28, pp. 216 (1996). <\/p>\n

Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Lagares, R., Franco, A., Fern\u00e1ndez, L., Cacabelos, R. Protective effects of CDP-choline against neurotoxic lesions in rat brain. X World Congress of Psychiatry, Madrid, August 23-28, pp. 216-217 (1996). <\/p>\n

Lagares, R., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., Franco, A., Cacabelos, R. Stereotaxic \uf062-amyloid implants into the hippocampus induce behavioral deficits in rats. X World Congress of Psychiatry, Madrid, August 23-28, pp. 217 (1996). <\/p>\n

Lao, J.I., Beyer, K., Miguel-Hidalgo, J.J., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Cacabelos, R. Apo-E allelic frequency and genetic risk calculation in Alzheimer\u2019s disease. X World Congress of Psychiatry, Madrid, August 23-28, pp. 247 (1996). <\/p>\n

Lagares, R., \u00c1lvarez, X.A., Zas, R., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Behavior and brain neuroimmune function in old mice treated chronically with anapsos. X World Congress of Psychiatry, Madrid, August 23-28, pp. 247 (1996). <\/p>\n

Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., \u00c1lvarez, X.A., Cacabelos, R. Correlation analysis between whole blood and serum histamine levels and transcranial Doppler ultrasonography parameters in healthy subjects and schizophrenic patients. X World Congress of Psychiatry, Madrid August 23-28, pp. 248 (1996). <\/p>\n

Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Franco-Maside, A., Miguel-Hidalgo, J.J., Polo, E., Cacabelos, R. Effects of S-12024 in rats with hippocampal neurodegeneration. X World Congress of Psychiatry, Madrid, August 23-28, pp. 249 (1996). <\/p>\n

\u00c1lvarez, X.A., Vara, E., Ayuso, J.L., Cacabelos, R. Effects of GHRP-6 on brain somatostatin levels in naive and cysteamine-treated rats. X World Congress of Psychiatry, Madrid, August 23- 28, pp. 249 (1996). <\/p>\n

Lao, J.I., Beyer, K., Miguel-Hidalgo, J.J., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Cacabelos, R Karyotypic figures found in Alzheimer\u2019s disease patients. X World Congress of Psychiatry, Madrid, August 23-28, pp. 250 (1996). <\/p>\n

\u00c1lvarez, X.A., Di\u00e9guez, C., Ayuso, J.L., Cacabelos, R. Learning impairment in rats with vitamin A-free diet: Influence on the testicular function. X World Congress of Psychiatry, Madrid, August 23-28, pp. 250-251 (1996). <\/p>\n

Beyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R. Molecular genetic analysis of Alzheimer\u2019s disease patients at Apo-E locus. X World Congress of Psychiatry, Madrid, August 23-28, pp. 251 (1996). <\/p>\n

\u00c1lvarez, X.A., Ayuso, J.L., Cacabelos, R. The hexapeptide GHRP-6 improves passive avoidance learning in rats. X World Congress of Psychiatry, Madrid, August 23-28, pp. 253 (1996). <\/p>\n

Cacabelos, R., Lagares, R., Fern\u00e1ndez-Novoa, L., Franco-Maside, A., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A. Anapsos: New therapeutic strategies for neurodegeneration and brain aging with natural neuroimmunotrophic factors. X World Congress of Psychiatry, Madrid, August 23-28, pp. 286 (1996). <\/p>\n

Cacabelos, R., Caama\u00f1o, J., G\u00f3mez, M.J., Franco-Maside, A., Vinagre, D., Novo, B. S-12024-2: A double-blind randomized placebo-controlled study in patients with Alzheimer disease. X World Congress of Psychiatry, Madrid, August 23-28, pp. 315 (1996). <\/p>\n

Sastre, I., \u00c1lvarez, X.A., Arauxo, A., Cacabelos, R. Standard operating procedures for filing documents in clinical trials. X World Congress of Psychiatry, Madrid, August 23-28, pp. 331 (1996). <\/p>\n

Beyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R. Molecular identification of trinucleotide expansion causing Huntington\u2019s disease without labelling with radionucleotides. X World Congress of Psychiatry, Madrid, August 23-28, pp. 342 (1996). <\/p>\n

Cacabelos, R. Enfermedad de Alzheimer y otras demencias. Mesa Redonda. M\u00e1ster Iberoamericano en Gerontolog\u00eda Social. Santiago de Chile. 10 Oct., (1996). <\/p>\n

Cacabelos, R. Enfermedad de Alzheimer: Gen\u00e9tica y Alternativas Terap\u00e9uticas. Jornada conmemorativa del D\u00eda Mundial del Alzheimer. Asociaci\u00f3n de Familiares de Enfermos de Alzheimer. Tenerife, 21 Sept., (1996). <\/p>\n

Cacabelos, R. Enfermedad de Alzheimer: Posibilidades preventivas y tratamiento. IV Jornadas de Informaci\u00f3n. \u201cEnfermedad de Alzheimer\u201d. D\u00eda Internacional del Alzheimer. Palencia, 17 Sept., (1996). <\/p>\n

Cacabelos, R. Epidemiolog\u00eda y diagn\u00f3stico de las demencias. Mesa Redonda: Demencia Senil. Enfermedad de Alzheimer. Enfermedad de Alzheimer: Factores etiopatog\u00e9nicos y diagn\u00f3stico cl\u00ednico-molecular. Libro de Ponencias y Comunicaciones. III Congreso de la Medicina General Espa\u00f1ola. La Coru\u00f1a, 17 Oct., pp. 28 (1996). <\/p>\n

Sellers, M.A., Carrera, C., Bustos, J.C., Cacabelos, R. Evoluci\u00f3n de la demencia senil seg\u00fan criterios cl\u00ednicos. Libro de Ponencias y Comunicaciones. III Congreso de la Medicina General Espa\u00f1ola, La Coru\u00f1a., pp. 302 (1996). <\/p>\n

Sellers, M.A., Rodr\u00edguez, B., Caama\u00f1o, J.M., Cacabelos, R. Evaluaci\u00f3n psicom\u00e9trica de los trastornos del sue\u00f1o en 231 pacientes con demencia senil. Libro de Ponencias y Comunicaciones. 111 Congreso de la Medicina General Espa\u00f1ola, La Coru\u00f1a. pp. 304 (1996). <\/p>\n

Sellers, M.A., Bustos, J.C., P\u00e9rez, L., Cacabelos, R. Rol del m\u00e9dico general en la asistencia al paciente demenciado. Libro de Ponencias y Comunicaciones. III Congreso de la Medicina General Espa\u00f1ola, La Coru\u00f1a. pp. 306 (1996). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., Cacabelos, R. Cerebrovascular changes associated with interleukin-1\uf062 (IL-1\uf062) and histamine (HA) levels in Alzheimer\u2019s disease. In: Cerebrovascular Pathology in Alzheimer\u2019s disease. A New York Academy of Sciences Conference. New Jersey, 12-15 Nov., pp. 22 (1996). <\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., \u00c1lvarez, X.A., Cacabelos, R. Global Deterioration Scale-related brain haemodynamics and histamine levels in Alzheimer disease and vascular dementia. In: Cerebrovascular Pathology in Alzheimer\u2019s disease. A New York Academy of Sciences Conference. New Jersey, 12-15 Nov., pp. 24 (1996).<\/p>\n

Beyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Sellers, M.A., Cacabelos, R. APOE E-4 allelic frequency in Alzheimer disease and vascular dementia in the Spanish population. In: Cerebrovascular Pathology in Alzheimer\u2019s disease. A New York Academy of Sciences Conference. New Jersey, 12-15 Nov., pp. 31 (1996). <\/p>\n

Cacabelos, R. Etiopatogenia y prospecciones terap\u00e9uticas de la enfermedad de Alzheimer. Actualidad Cient\u00edfica y Sociosanitaria de la enfermedad de Alzheimer. Fundaci\u00f3n Ram\u00f3n Areces, Madrid, l0 Jun. (1996). <\/p>\n

Cacabelos, R. (Representaci\u00f3n Ministerio de Sanidad ante UE) Alzheimer\u2019s Disease and Related Disorders. European Conference. Limerick, Ireland, Nov. 20-22 (1996). <\/p>\n

Cacabelos, R, Enfermedad de Alzheimer. Factores etiopatog\u00e9nicos y evaluaci\u00f3n gen\u00e9tica. Programa de Formaci\u00f3n Permanente. Federaci\u00f3n Farmac\u00e9utica Valenciana. 10 Jun., (1996). <\/p>\n

Cacabelos, R. Enfermedad de Alzheimer: Bases etiopatog\u00e9nicas y estrategias terap\u00e9uticas. Simposio. Salud Mental y Psiquiatr\u00eda en el umbral del nuevo milenio, I Reuni\u00f3n Regional Caribe y Pa\u00edses Bolivarianos \u201cCarlos Alberto Segu\u00edn\u201d. XIV Congreso Nacional de Psiquiatr\u00eda \u201cHonorio Delgado\u201d. Lima 28 Nov.-1 Dic. (1996). <\/p>\n

Cacabelos, R. Avances en Demencia (Parte I). Simposio. Salud Mental y Psiquiatr\u00eda en el umbral del nuevo milenio. I Reuni\u00f3n Regional Caribe y Paises Bolivarianos \u201cCarlos Alberto Segu\u00edn\u201d. XIV Congreso Nacional de Psiquiatr\u00eda \u201cHonorio Delgado\u201d. Lima, 28 Nov.-1 Dic. (1996). <\/p>\n

Cacabelos, R. Avances en Demencia (Parte II). Simposio. Salud Mental y Psiquiatr\u00eda en el umbral del nuevo milenio. I Reuni\u00f3n Regional Caribe y Paises Bolivarianos \u201cCarlos Alberto Segu\u00edn\u201d. XIV Congreso Nacional de Psiquiatr\u00eda \u201cHonorio Delgado\u201d. Lima, 28 Nov.-1 Dic. (1996). <\/p>\n

Cacabelos, R. Enfermedad de Alzheimer: Tratamientos Etiopatog\u00e9nicos. III Reuni\u00f3n. Fundaci\u00f3n Mapfre Medicina. Da\u00f1o Cerebral y Calidad de Vida. Demencias. Madrid, 14-15 Nov (1996). <\/p>\n

Cacabelos, R. La enfermedad de Alzheimer hoy. Tratamiento y prevenci\u00f3n. Programa Aula Magna Tirso de Molina. Fundaci\u00f3n Caja Rural. Soria. 11 Nov. (1996). <\/p>\n

Beyer, K., Lao, J.I., Sellers, M.A., \u00c1lvarez, X.A., Cacabelos, R. Association between presenilin-l (S182) gene polymorphism and Alzheimer\u2019s disease in the Spanish population. 4th Joint Clinical Genetics Meeting of the 28th Annual March of Dimes Clinical Genetics Conference and the American College of Medical Genetics 4th Annual Meeting. Ft. Lauderdale, Florida, pp. A50. Feb. 28-March 2 (1997). <\/p>\n

Lao, J.I., Beyer, K., Cacabelos, R., De la Fuente, R. Three new mutations in the GTP-CHI gene in Spanish families with hereditary progressive and dopa-responsive dystonia. 4th Joint Clinical Genetics Conference of the 28th Annual March of Dimes Clinical Genetics Conference and the American College of Medical Genetics 4th Annual Meeting. Ft. Lauderdale, Florida, pp. A53 (1997). <\/p>\n

A large GAA expanded allele in a family with Friedreich\u2019s ataxia: A case report. 4th Joint Clinical Genetics Meeting of the 28th Annual March of Dimes Clinical Genetics Conference and the American College of Medical Genetics 4th Annual Meeting. Ft. Lauderdale, Florida, pp. A54. (1997). <\/p>\n

Cacabelos, R. Etiopatogenia y estrategia terap\u00e9utica en la enfermedad de Alzheimer. I Symposium Alzheimer. Residencia Nuestra Se\u00f1ora del Carmen, Valencia (17.3.1997). <\/p>\n

Cacabelos, R. Preventive strategies in Alzheimer\u2019s Disease and Related Disorders: Genotyping and drug monitoring. International Workshop. The role of the glutamatergic system in neurodegeneration and dementia. Osaka. April 5 (1997). <\/p>\n

Cacabelos, R. Therapeutic strategies in Alzheimer\u2019s disease: Novel compounds with neuroimmunotrophic activity. International Workshop. Brain Aging and Alzheimer\u2019s Disease. From Molecular to Clinical Approaches. Havana, April 10-12, pp. 14-15 (1997). <\/p>\n

Cacabelos, R. Neuroimmune dysfunction in Alzheimer\u2019s disease. International Workshop. Brain Aging and Alzheimer\u2019s Disease. From Molecular to Clinical Approaches. Havana, April 10-12, pp. 15 (1997).<\/p>\n

Cacabelos, R. Advances in brain histamine research. XXVI Annual Meeting. European Histamine Research Society, Seville, May 14-14 (1997). <\/p>\n

Cacabelos, R., Lao, J.I., Beyer, K., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L. Central and peripheral histamine in neurodegenerative and psychiatric disorders: genetic markers and histamine levels. XXVI Annual Meeting. European Histamine Research Society. Seville, May 14-17, pp. 10 (1997). <\/p>\n

Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Miguel-Hidalgo, J.J., Cacabelos, R. Brain histamine in an animal model of neuronal degeneration. XXVI Annual Meeting. European Histamine Research Society, Seville, May 14-17, pp. 104 (1997). <\/p>\n

Maneiro, E., Fern\u00e1ndez-Novoa, L., Lombardi, V., Cacabelos, R. Effects of histamine on lactate dehydrogenase (LDH) release in cultured rat endothelial cells. XXVI Annual Meeting. European Histamine Research Society. Seville, May 14-17, pp. 105 (1997). <\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., \u00c1lvarez, X.A., Cacabelos, R. Whole blood and serum histamine in healthy subjects and in schizophrenic patients: Correlation analysis with transcranial Doppler ultrasonography. XXVI Annual Meeting. European Histamine Research Society. Seville, May 14-17, pp. 106 (1997). <\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., \u00c1lvarez, X.A., Cacabelos, R. Histamine levels in Alzheimer\u2019s disease and vascular dementia patients according to Global Deterioration Scale Staging: Correlation studies with brain hemodynamic parameters. XXVI Annual Meeting. European Histamine Research Society. Seville, May 14-17, pp. 107 (1997). <\/p>\n

Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Cacabelos, R. Effects of famotidine on the levels of blood histamine in healthy subjects: Correlation studies with brain mapping. XXVI Annual Meeting. European Histamine Research Society. Seville, May 14-17, pp. 108 (1997). <\/p>\n

Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Cacabelos, R. Blood histamine levels in depression. XXVI Annual Meeting. European Histamine Research Society. Seville, May 14-17, pp. 109 (1997). <\/p>\n

Mouzo, R., \u00c1lvarez, X.A., Sellers, A., Pichel, V., Lao, J.I., Caama\u00f1o, J.M., Laredo, M., P\u00e9rez, P., Beyer, K., Alcaraz, M., R\u00faa, M.C., Fern\u00e1ndez-Novoa, L., Fern\u00e1ndez, R., Carrera, C., Cacabelos, R. Blood pressure and apolipoprotein-E (APOE) in senile dementia. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May l 8-23, pp. 6 (1997). <\/p>\n

Laredo, M., \u00c1lvarez, X.A., Mouzo, R., P\u00e9rez, P., Lao, J.I., Beyer, K., Sellers, A., Pichel, V., Caama\u00f1o, J.M., Rodr\u00edguez, S., Iglesias, E., Varela, B., Cacabelos, R. Psychometric evaluation and APOE genotyping in senile dementia. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 8 (1997). <\/p>\n

Maneiro, E., Lombardi, V., D\u00edaz, J., Cacabelos, R. Effects of anapsos on adult rat microglial cell cultures. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 10 (1997). <\/p>\n

Sellers, A., P\u00e9rez, P., Rodr\u00edguez, B., Pichel, V.M., Caama\u00f1o, J.M., Laredo, M., Alcaraz, M., \u00c1lvarez, X.A., Cacabelos, R. Dementia-associated sleep disorders. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 12 (1997). <\/p>\n

P\u00e9rez, L., Sellers, A., Caama\u00f1o, J.M., Lao, J.I., Beyer, K., Bustos, J.C., Cacabelos, R. Clinical evaluation at the onset of senile dementia. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 13 (1997). <\/p>\n

Sellers, A., Carrera, C., Bustos, J.C., Caama\u00f1o, J.M., Rodr\u00edguez, B., Mouzo, R., P\u00e9rez, P., Lao, J.I., Beyer, K., \u00c1lvarez, X.A., Cacabelos, R. Cognitive and non-cognitive symptoms in senile dementia. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 13 (1997). <\/p>\n

Maneiro, E., Lombardi, V., Cacabelos, R. Adult rat microglial cell cultures: An in vitro cellular model to study the effect of IL-1\uf062 and \uf062-amyloid on microglial activation. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 41 (1997). <\/p>\n

Maneiro, E., Lombardi, V., Cacabelos, R. Rat endothelial cell cultures: An in vitro cellular model to study the cytotoxic effect of \uf062-amyloid, LPS, histamine and serum from AD patients on endothelial cell cultures. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 41 (1997). <\/p>\n

Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R. \uf062-Amyloid(1-40)-induced neurodegeneration in the rat hippocampal neurons of the CA1 subfield. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 42 (1997). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Perea, J.E., Daniele, D., Cacabelos, R. Citicoline reverses learning impairment in rats with hippocampal injections of \uf062-amyloid (1-40). Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 42 (1997). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Hippocampal implants of \uf062-amyloid induce memory deficits in rats. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 43 (1997). <\/p>\n

Cacabelos, R. Therapeutic strategies in Alzheimer\u2019s disease: pleiotropic versus etiopathogenic treatment. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 48 (1997). <\/p>\n

Beyer, K., Lao, J.I., Cacabelos, R. Allele differences in the presenilin-2 gene in Alzheimer\u2019s disease. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 56 (1997). <\/p>\n

Beyer, K., Lao, J.I., Cacabelos, R. A rapid and easy method for presenilin-1 gene screening. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 57 (1997). <\/p>\n

Corzo, L., Fern\u00e1ndez-Novoa, L., Zas, R., Beyer, K., Lao, J.I., \u00c1lvarez, X.A., Cacabelos, R. Influence of the APOE genotype on serum ApoE levels from Alzheimer\u2019s disease patients in the Spanish population. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 59 (1997). <\/p>\n

Pichel, V.M., Caama\u00f1o, J.M., Mouzo, R., \u00c1lvarez, X.A., P\u00e9rez, P., Laredo, M., Alcaraz, M., Lao, J.I., Beyer, K., Sellers, A., Cacabelos, R. Changes in cerebral blood flow associated with disease staging and APOE genotyping in patients with senile dementia. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 62 (1997). <\/p>\n

P\u00e9rez, P., \u00c1lvarez, X.A., Laredo, M., Mouzo, R., Sellers, A., Pichel, V.M., Caama\u00f1o, J.M., Lao. J.I., Beyer, K., Novo, B., Alcaraz, M., Cacabelos, R. Brain activity mapping and APOE genotyping in senile dementia. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 62 (1997). <\/p>\n

Lao, J.I., Beyer, K., Cacabelos, R. Centromere disturbances affecting Alzheimer\u2019s disease lymphocyte metaphases. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 62 (1997). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., D\u00edaz, J., Sempere, J.M., Cacabelos, R. Anapsos improves learning and memory in rats with \uf062-amyloid(1-28) deposits into the hippocampus. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 64 (1997). <\/p>\n

Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R. Neuroprotection by CDP-choline in a model of hippocampal degeneration after deposits of fragment 1-40 of \uf062-amyloid. 6th World Congress Biological Psychiatry, June 22-27, Nice. Biol. Psychiatry, 42(1S):39S (1997). <\/p>\n

Maneiro, E., Lombardi, V., Cacabelos, R. Cytotoxicity induced by \uf062-amyloid, histamine, LPS and serum from AD patients on rat endothelial cells. 6th World Congress Biological Psychiatry, June 22- 27, Nice. Biol. Psychiatry, 42(1S):90-91S (1997). <\/p>\n

Maneiro, E., Lombardi, V., Cacabelos, R. \uf062-Amyloid and IL-1\uf062 effects on rat microglial cell cultures. 6th World Congress Biological Psychiatry. June 22-27, Nice. Biol. Psychiatry, 42(1S):91S (1997). <\/p>\n

Sellers, A., \u00c1lvarez, X.A., Carrera, C., Bustos, J.C., Caama\u00f1o, J.M., Mouzo, R., P\u00e9rez, P., Lao, J.I., Beyer, K., Cacabelos, R. Cognitive and non-cognitive symptoms in patients with senile dementia. 6th World Congress Biological Psychiatry, June 22-27, Nice. Biol. Psychiatry 42(1S):93S (1997). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Perea, J.E., Daniele, D., Cacabelos, R. Citicoline antagonizes bromazepam-induced amnesia in rats. 6th World Congress Biological Psychiatry June 22-27, Nice. Biol. Psychiatry, 42(1S):95S (1997). <\/p>\n

\u00c1lvarez, X.A., Laredo, M., Corzo, L., Perea, J.E., Daniele, D., Cacabelos, R. Citicoline improves memory in elderly subjects. 6th World Congress Biological Psychiatry, June 22-27, Nice. Biol. Psychiatry 42(1 S):95S (1997). <\/p>\n

Lao, J.I., Beyer, K., \u00c1lvarez, X.A., Cacabelos, R. Analysis of a polymorphic tetranucleotide repeat in the TH gene in Spanish psychiatric patients. 6th World Congress Biological Psychiatry, June 22- 27, Nice. Biol. Psychiatry 42(1S):101S (1997). <\/p>\n

Sellers, A., \u00c1lvarez, X.A., Rodr\u00edguez, B., Caama\u00f1o, J.M., Laredo, M., Pichel, V.M., Alcaraz, M., Cacabelos, R. Sleep disorders in patients with senile dementia. 6th World Congress Biological Psychiatry. June 22-27, Nice. Biol. Psychiatry, 42(1S): 115S (1997). <\/p>\n

Beyer, K., Lao, J.I., Sellers, M.A., \u00c1lvarez, X.A., Cacabelos, R. Association between presenilin-l (S182) gene polymorphism and Alzheimer\u2019s disease in the Spanish population. 6th World Congress Biological Psychiatry. June 22-27, Nice. Biol. Psychiatry 42(1S):120S (1997). <\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., \u00c1lvarez, X.A., Cacabelos, R. Whole blood and serum histamine in healthy subjects and schizophrenic patients: Correlation analysis with transcraneal Doppler ultrasonography. 6th World Congress Biological Psychiatry. June 22-27, Nice. Biol. Psychiatry, 42(1S):176-177S (1997). <\/p>\n

Pichel, V.M., Caama\u00f1o, J.M., Mouzo, R., \u00c1lvarez, X.A., P\u00e9rez, P., Laredo, M., Alcaraz, M., Lao, J.I., Beyer, K., Sellers, A., Cacabelos, R. Cerebral blood flow in senile dementia: Changes associated with disease staging and APOE genotyping. 6th World Congress Biological Psychiatry. June 22-27, Nice. Biol. Psychiatry, 42(1S):211S (1997). <\/p>\n

Cacabelos, R. Alzheimer\u2019s disease: present and future. Symposium II. New vistas on CNS pharmacology. Innsbruck University, Innsbruck, Austria, Sept. 12 (1997). <\/p>\n

Cacabelos, R. Etiopatogenia de la enfermedad de Alzheimer. XVII Congreso Venezolano de Psiquiatr\u00eda. Nov. 5-8, Maracaibo (1997). <\/p>\n

Cacabelos, R. Controversias en el tratamiento de la demencia. XVII Congreso venezolano de Psiquiatr\u00eda. Nov. 5-8, Maracaibo (1997). <\/p>\n

Cacabelos, R. Tratamiento farmacol\u00f3gico de las demencias: especificidad genot\u00edpica de las respuestas terap\u00e9uticas en la enfermedad de Alzheimer. XVII Congreso venezolano de psiquiatr\u00eda. Nov. 5-8, Maracaibo (1997). <\/p>\n

Lombardi, V., Cacabelos, R. Primary microglial cell cultures in the study of novel marine-derived compounds. 1st EuroConference on Marine Natural Products. Athens, Nov. 2-6, pp. 52 (1997). <\/p>\n

Lombardi, V., Cacabelos, R. Biological effects of the fish extract E-CAB-9401l in rats. lst EuroConference on Marine Natural products. Athens, Nov. 2-6, pp. 120 (1997). <\/p>\n

Lombardi, V., Cacabelos, R. E-JUR-94013 Marine fish extract: Neuroimmunological studies in adult Sprague-Dawley rats. lst EuroConference on Marine Natural Products. Athens, Nov. 2-6, pp. 121 (1997). <\/p>\n

Lombardi, V., Reguera, R., Cacabelos, R. Neuroimmunological properties of Atlantic starfish-derived compounds. lst EuroConference on Marine Natural Products. Athens, Nov. 2-6, pp. 122 (1997).<\/p>\n

Lombardi, V., Cacabelos, R. Neuroimmunological studies with the fish extract E-SAR-94010 in rats. lst EuroConference on Marine Natural Products. Athens, Nov. 2-6, pp. 123 (1997). <\/p>\n

Cacabelos, R. Bio\u00e9tica asistencial del anciano con enfermedad neurodegenerativa. Prevenci\u00f3n gen\u00e9tica de la demencia. VI Jornadas Nacionales y II Jornadas Internacionales de Bio\u00e9tica. Envejecer cuando nace un siglo. Granada, Sept. 25-26, pp. 20-23 (1998). <\/p>\n

Cacabelos, R. Enfermedad de Alzheimer. Etiopatogenia y tratamiento. Simposio Internacional. Enfermedad de Alzheimer, Del Diagn\u00f3stico al abordaje terap\u00e9utico integral. Wyeth, M\u00e9xico, Feb. 28, pp. 35-52 (1998). <\/p>\n

Cacabelos, R., Lao, J.I., Beyer, K., Sellers, M.A., Laredo, M., Alcaraz, M., \u00c1lvarez, X.A. Genotype-specific therapeutic response in Alzheimer disease with novel compounds: New designs in drug clinical trials and preventive strategies. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 24 (1998). <\/p>\n

Khachaturian, Z., Radebaugh, T., Thal, L., Gauthier, S., Cacabelos, R, Sano, M., Leber, P. International Working Group on Prevention of Alzheimer\u2019s Disease. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 60 (1998). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., Cacabelos, R. Intrahippocampal injections of \uf062-amyloid fragments impair learning and memory in rats. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 134 (1998). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Perea, J.E., Daniele, D., Cacabelos, R. Citicoline reverses learning impairment induced by \uf062-amyloid injections into the rat hippocampus. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 134 (1998). <\/p>\n

\u00c1lvarez, X.A., Laredo, M., Corzo, L., Zas, R., Mouzo, R., Perea, J.E., Daniele, D., Cacabelos, R. Citicoline enhances memory performance in elderly subjects. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 135 (1998). <\/p>\n

\u00c1lvarez, X.A., Sellers, M.A., Mouzo, R., Pichel, V., P\u00e9rez, P., Laredo, M., Caama\u00f1o, J.M., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Lao, J.l., Beyer, K., Alcaraz, M., Cacabelos, R. Effects of CDP-choline on cognitive function and brain bioelectrical activity and hemodynamic parameters in Alzheimer disease patients: A double-blind placebo-controlled study. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 135 (1998). <\/p>\n

\u00c1lvarez, X.A., Sellers, M.A., Mouzo, R., Pichel, V., P\u00e9rez, P., Laredo, M., Caama\u00f1o, J.M., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Lao, J.I., Beyer, K., Alcaraz, M., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Double-blind randomized placebo-controlled study with anapsos in senile dementia. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 136 (1998). <\/p>\n

Beyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., Cacabelos, R. V1481: A novel mutation in the predicted TM2 domain of the presenilin-2 gene in a Spanish patient with late-onset Alzheimer\u2019s disease. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April l 5-18, pp. 139 (1998). <\/p>\n

Cacabelos, R. Protocol for preventive intervention in dementia: Gene-specific therapeutic responses with multifactorial strategies (combined treatment). Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp, 140 (1998). <\/p>\n

Corzo, L., Fern\u00e1ndez-Novoa, L., Zas, R., Beyer, K., Lao, J.I., Laredo, M., \u00c1lvarez, X.A., Cacabelos, R. Serum ApoE and lipid levels according to APOE genotype in Alzheimer disease. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 141 (1998). <\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., Beyer, K., Zas, R., Lao, J.I., Laredo, M., \u00c1lvarez, X.A., Cacabelos, R. Histamine levels in Alzheimer\u2019s disease and vascular dementia according to GDS staging. APOE genetic profile evaluation. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 142 (1998). <\/p>\n

Lao, J.I., Beyer, K., Fern\u00e1ndez-Novoa, L., Cacabelos, R. A possible epistasia between presenilin-l gene and APOE-E4 allele on Alzheimer disease in the Spanish population. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 149 (1998). <\/p>\n

Laredo, M., Pichel, V., \u00c1lvarez, X.A., Mouzo, R., P\u00e9rez, P., Lao, J.I., Beyer, K., Novo, B., Alcaraz, M., Cacabelos, R. Influence of diagnosis and APOE genotype on cognitive performance in senile dementia: a prospective study. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 150 (1998). <\/p>\n

Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Quack, G., Cacabelos, R. Protection by memantine against A\uf062(1-40)-induced neurodegeneration in the CA1 subfield. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 153 (1998). <\/p>\n

P\u00e9rez, P., Pichel, V., \u00c1lvarez, X.A., Laredo, M., Mouzo, R., Lao, J.I., Beyer, K., Novo, B., Alcaraz, M., Cacabelos, R. Changes in brain bioelectrical activity associated with disease stage and APOE genotype in senile dementia. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 155 (1998). <\/p>\n

Pichel, V., Caama\u00f1o, J.M., Mouzo, R., \u00c1lvarez, X.A., P\u00e9rez, P., Laredo, M., Alcaraz, M., Lao, J.I., Beyer, K., Sellers, A., Cacabelos, R. Changes in cerebral blood flow associated with disease staging and APOE genotype in patients with senile dementia. Fifth International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 15-18, pp. 156 (1998). <\/p>\n

Cacabelos, R. Etiopatogenia da doen\u00e7a de Alzheimer e suas implica\u00e7oes no tratamento. Simposium Envelhecimiento e Demencias. Coimbra, Portugal, Junho 26-27 (1998). <\/p>\n

Beyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Identification of a novel mutation (V1481) in the TM2 domain of the presenilin-2 gene in a patient with late-onset Alzheimer disease. 6th International Conference on Alzheimer\u2019s Disease and Related Disorders. Amsterdam, July l 8-23. Neurobiol. Aging, 19\/4S:S87 (1998). <\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., Lombardi, V. An animal model of neurodegeneration induced by injections of \uf062-amyloid into the rat hippocampus: Behavioral characterization. 6th International Conference on Alzheimer\u2019s Disease and Related Disorders. Amsterdam, July 18-23. Neurobiol. Aging, 19\/4S:S126 (1998). <\/p>\n

Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Quack, G., Cacabelos, R. Protection of memantine against A\uf062(1-40)-induced neurodegeneration in the CA1 subfield. 6th International Conference on Alzheimer\u2019s Disease and Related Disorders. Amsterdam, July 18-23. Neurobiol. Aging, 19\/4S:S129 (1998). <\/p>\n

\u00c1lvarez, X.A., Laredo, M., Corzo, L., Zas, R., Mouzo, R., Fern\u00e1ndez-Novoa, L., Perea, J.E., Daniele, D., Cacabelos, R. Memory-enhancing effects of citicoline in elderly nondemented people. 6th International Conference on Alzheimer\u2019s Disease and Related Disorders. Amsterdam, July 18- 23. Neurobiol. Aging, 19\/4S:S184 (1998). <\/p>\n

Mouzo, R., \u00c1lvarez, X.A., Sellers, M.A., Pichel, V.M., P\u00e9rez, P., Laredo, M., Caama\u00f1o, J.M., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Lao, J.I., Beyer, K., Alcaraz, M., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Treatment with anapsos in senile dementia: A double-blind placebo-controlled study. 6th International Conference on Alzheimer\u2019s Disease and Related Disorders. Amsterdam, July 18- 23. Neurobiol. Aging, 19\/4S:S184 (1998). <\/p>\n

Lombardi, V., Garc\u00eda, M., Cacabelos, R. Neuroimmunomodulation induced by cerebrolysin, a brain-derived peptide preparation, on primary microglial cell cultures. 6th International Conference on Alzheimer\u2019s Disease and Related Disorders. Amsterdam, July 18-23. Neurobiol. Aging, 19\/4S:S200 (1998). <\/p>\n

Vigo-Pelfrey, C., Cacabelos, R., \u00c1lvarez, X.A., Allison, C. Neurostrol, a potent anti-inflammatory drug to treat Alzheimer\u2019s disease. 6th International Conference on Alzheimer\u2019s Disease and Related Disorders. Amsterdam, July 18-23. Neurobiol. Aging, 19\/4S:S262 (1998). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., Cacabelos, R. Beta-amyloid injections into the rat hippocampus impair learning and memory. XXlst CINP Congress, Glasgow, July 12-16, pp. 391 (1998). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Perea, J.E., Cacabelos, R. Citicoline reverses learning impairment in rats with hippocampal neurodegeneration induced by beta-amyloid. XXlst CINP Congress, Glasgow, July 12-16, pp. 391 (1998). <\/p>\n

Cacabelos, R., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Quack, G. Protection of memantine against A\uf062(1-40)-induced neurodegeneration in the CA1 subfield. XXIst CNIP Congress, Glasgow, July 12- 16, pp. 392 (1998). <\/p>\n

Cacabelos, R., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A. Beta-amyloid-induced neurodegeneration in the rat hippocampal neurons of the CA1 subfield. XXlst CNIP Congress, Glasgow, July 12-16, pp. 392 (1998). <\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Miguel-Hidalgo, J.J. Effects of hippocampal beta-amyloid injections on histamine levels, SOD, and AchE activities in the rat brain. XXlst CNIP Congress, Glasgow, July 12-16, pp. 392 (1998). <\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Perea, J.E., Daniele, D., Cacabelos, R. Citicoline antagonizes bromazepam-induced amnesia in rats. XXlst CMP Congress, Glasgow, July 12-16, pp. 396 (1998).<\/p>\n

Cacabelos, R., Lombardi, V., Garc\u00eda, M., \u00c1lvarez, X.A. Neuroimmunotrophic compounds from marine organisms. XXIst CNIP Congress, Glasgow, July 12-16, pp. 433 (1998). <\/p>\n

Cacabelos, R. Los centros de investigaci\u00f3n como estructura de apoyo social. II Reuni\u00f3n Latinoamericana de Asociaciones de Alzheimer y Primer Foro Iberoamericano sobre el Envejecimiento Cerebral. Oaxaca, M\u00e9xico, 17-19 Marzo, 1999.<\/p>\n

Cacabelos, R. La comunicaci\u00f3n con el enfermo con demencia. Por una relaci\u00f3n m\u00e1s humana. X Jornadas de Humanizaci\u00f3n. \u201cEl Atardecer de la Mente Humana\u201d. Hermanos Hospitalarios de San Juan de Dios. Centro San Rafael, Granada, 14 Abril, 1999.<\/p>\n

Mesa, M.D., Fern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Cacabelos, R. Genotype frequencies in Alzheimer\u2019s disease and vascular dementia in the Spanish population. Restauraci\u00f3n Neurol\u00f3gica \u201999. CIREN, Habana, 23-25 Feb, pp. 62 (1999).<\/p>\n

Lombardi, V.R.M., Garc\u00eda, M., Perea, E., Daniele, D., Cacabelos, R. Reduction of in vitro neuronal apoptosis by citicoline treatment. Restauraci\u00f3n Neurol\u00f3gica \u201999. CIREN, Habana, 23-25 Feb., pp. 61 (1999).<\/p>\n

Lombardi, V.R.M., Garc\u00eda, M., Rey, L., Cacabelos, R. Neuroimmune dysfunction in Alzheimer disease patients. Restauraci\u00f3n Neurol\u00f3gica \u201999, CIREN, Habana, 23-25 Fe., pp. 61 (1999).<\/p>\n

Fern\u00e1ndez-Novoa, L., Mesa, M.D., \u00c1lvarez, X.A., Cacabelos, R. Genetic associations and risk factors in Alzheimer\u2019s disease. Restauraci\u00f3n Neurol\u00f3gica \u201999, CIREN, Habana, 23-25 Feb., pp. 60 (1999).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Antiapoptotic effects of CDP-choline in a combined (hypoperfusion + \uf062-amyloid) animal model of hippocampal neurodegeneration. Restauraci\u00f3n Neurol\u00f3gica \u201999, CIREN, Habana, 23-25 Feb., pp. 58 (1999).<\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Sampedro, C., Lombardi, V., Cacabelos, R., Windisch, M. Neuroimmunotrophic effects of cerebrolysin in an animal model of neurodegeneration induced by \uf062-amyloid. Restauraci\u00f3n Neurol\u00f3gica \u201999, CIREN, Habana, 23-25 Feb., pp. 58-59 (1999).<\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Lombardi, V. Basic mechanisms of neuroprotection and genotype-related therapeutic response in Alzheimer\u2019s disease: Implications for active treatment and prevention in dementia. Restauraci\u00f3n Neurol\u00f3gica \u201999, CIREN, Habana, 23-25 Feb., pp. 56 (1999).<\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Sampedro, C., Lombardi, V., Cacabelos, R., Windisch, M. Cerebrolysin reverses learning impairment and brain neuroimmune activation in an animal model of neurodegeneration induced by \uf062-amyloid. Keystone Symposia on Molecular & Cellular Biology. Molecular Mechanisms in Alzheimer\u2019s Disease. Taos, New Mexico, March 3-9, pp. 48 (1999).<\/p>\n

Lombardi, V.R.M., Garc\u00eda, M., Rey, L., Cacabelos, R. Peripheral immunological abnormalities and lymphocyte dysfunction in Alzheimer disease. Keystone Symposia on Molecular & Cellular Biology. Molecular Mechanisms in Alzheimer\u2019s Disease. Taos, New Mexico, March 3-9, pp. 52 (1999).<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V., Mesa, M.D., Cacabelos, R. Genetic risk factors in Alzheimer disease and vascular dementia in the Spanish population. Keystone Symposia on Molecular & Cellular Biology. Molecular Mechanisms in Alzheimer\u2019s Disease. Taos, New Mexico, March 3-9, pp. 35 (1999).<\/p>\n

Cacabelos, R., Mesa, M.D., Fern\u00e1ndez-Novoa, L. Association between genotypes and risk factors in Alzheimer\u2019s disease. Keystone Symposia on Molecular & Cellular Biology. Molecular Mechanisms in Alzheimer\u2019s Disease. Taos, New Mexico, March 3-9, pp. 35 (1999).<\/p>\n

Cacabelos, R. Gen\u00e9tica de la enfermedad de Alzheimer. Diagn\u00f3stico Molecular y Predictivo de Riesgo Familiar. Simposio Regional Norte-Sur APAL. Asociaci\u00f3n Psiqui\u00e1trica de America Latina. Isla Margarita, Venezuela. Nov. 23-27, pp. 54-55 (1999).<\/p>\n

Cacabelos, R. Tratamiento farmacol\u00f3gico de la demencia senil. Simposio Regional Norte-Sur APAL. Asociaci\u00f3n Psiqui\u00e1trica de America Latina. Isla Margarita, Venezuela. Nov. 23-27, pp. 70-71 (1999).<\/p>\n

Laredo, M., Couceiro, V., P\u00e9rez, P., Anido, R., Figueroa, J., Garc\u00eda, E., Manti\u00f1\u00e1n, N.P., \u00c1lvarez, X.A., Cacabelos, R. Neurorehabilitaci\u00f3n en traumatismos craneoencef\u00e1licos. I Congreso Nacional de Psicolog\u00eda Cl\u00ednica y de la Salud. Orense, 23-27 Nov., pp. 140-141 (1999).<\/p>\n

Laredo, M., G\u00f3mez, E., Gallo, E., Corzo, L., Couceiro, V., Anido, R., P\u00e9rez, P., \u00c1lvarez, X.A., Cacabelos, R. Evaluaci\u00f3n de las funciones del lenguaje en la demencia senil. I Congreso Nacional de Psicolog\u00eda Cl\u00ednica y de la Salud. Orense, 23-27 Nov., pp. 114-115 (1999).<\/p>\n

Cacabelos, R. Cerebrolysin enhances brain bioelectrical activity alpha and improves memory performance in humans. Internal Meeting Research Initiative EBEWE. Graz, Austria. Sept. 23 (1999).<\/p>\n

Cacabelos, R., Mesa, M.D., Fern\u00e1ndez-Novoa, L. Genetic epidemiology of risk factors in Alzheimer\u2019s disease. Human Genome Meeting. Brisbane, Australia, 27-30 March, pp. 26 (1999).<\/p>\n

Mesa, M.D., Fern\u00e1ndez-Novoa, L., Lombardi, V.R., \u00c1lvarez, X.A., Cacabelos, R. ADGT-Kit: A diagnostic aid for the analysis of genetic risk factors involved in the etiopathogenesis of Alzheimer\u2019s disease and vascular dementia. Human Genome Meeting. Brisbane, Australia, 27-30 March, pp. 26 (1999).<\/p>\n

\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Alcaraz, M., Sempere, J.M., D\u00edaz, J., Cacabelos, R. A double-blind placebo-controlled study with anapsos in vascular dementia and Alzheimer disease. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 23 (1999).<\/p>\n

P\u00e9rez, P., Corzo, L., \u00c1lvarez, X.A., Laredo, M., Cacabelos, R. Changes in brain bioelectrical activity associated with cognitive and behavioral function in dementia. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 27 (1999).<\/p>\n

Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Olano, M., Mesa, D., Cacabelos, R. Serum apolipoprotein E and lipid levels in vascular dementia and Alzheimer disease. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 30 (1999).<\/p>\n

Laredo, M., G\u00f3mez, E., Gallo, E., Corzo, L., \u00c1lvarez, X.A., Cacabelos, R. Evaluation of language functions in senile dementia. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 35 (1999).<\/p>\n

Laredo, M., P\u00e9rez, P., Couceiro, V., Anido, R., Corzo, L., \u00c1lvarez, X.A., Cacabelos, R. Sleep disorders in vascular dementia and Alzheimer disease. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 35 (1999).<\/p>\n

Fern\u00e1ndez-Novoa, L., Mesa, M.D., Olano, M., Lombardi, V., \u00c1lvarez, X.A., Cacabelos, R. Evaluation of the genetic profile in Alzheimer\u2019s disease and vascular dementia. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 41 (1999).<\/p>\n

Fern\u00e1ndez-Novoa, L., Mesa, M.D., de Olano, M., Lombardi, V., \u00c1lvarez, X.A., Cacabelos, R. Genotype characterization in Alzheimer disease according to gender, disease expression and age at onset. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 41 (1999).<\/p>\n

de Olano, M., Mesa, M.D., Blanco, A., Fern\u00e1ndez-Novoa, L., Corzo, L., Cacabelos, R. Angiotensin-converting enzyme I\/D polymorphism in cerebrovascular pathology. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 41 (1999).<\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Sampedro, C., Lombardi, V., Windisch, M., Cacabelos, R. Neuroimmunotrophic effects of Cerebrolysin in an animal model of hippocampal degeneration induced by \uf062-amyloid. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 43 (1999).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. CDP-Choline reduces neuronal apoptosis in rats with brain hypoperfusion and hippocampal \uf062-amyloid implants. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 43 (1999).<\/p>\n

Cacabelos, R. Os inhibidores da acetilcolinesterasa como factor de esperan\u00e7a no tratamento da doen\u00e7a de Alzheimer. O Idoso no Ano 2000. Velhos sao os Trapos. Auditorio dos Hospitais da Universidade de Coimbra. Associa\u00e7ao Portuguesa de Gerontopsiquiatr\u00eda. Coimbra, 20-22 Janeiro (2000).<\/p>\n

Cacabelos, R. Genetica da doen\u00e7a de Alzheimer. Workshop Universidade de Coimbra. 22 Janeiro (2000).<\/p>\n

Cacabelos, R. Avances en la etiolog\u00eda de las demencias. VII Congreso Nacional. Asociaci\u00f3n Colombiana de Psiquiatr\u00eda Biol\u00f3gica. Pereira, Colombia, 18-19 Marzo (2000).<\/p>\n

Cacabelos, R. Farmacogen\u00e9tica de las demencias. VII Congreso Nacional. Asociaci\u00f3n Colombiana de Psiquiatr\u00eda Biol\u00f3gica. Pereira, Colombia, 18-19 Marzo (2000).<\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V., \u00c1lvarez, X.A. Genotype-specific apoptosis and therapeutic response in Alzheimer disease: Implications for drug design and clinical trials. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 41 (2000).<\/p>\n

\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., De Olano, M., Sampedro, C., Lombardi, V., Windisch, M., Cacabelos, R. Cerebrolysin exerts neuroimmunotrophic and neuroprotective effects in an animal model of hippocampal neurodegeneration. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 197 (2000).<\/p>\n

\u00c1lvarez, X.A., Lombardi, V.R.M., Corzo, L., P\u00e9rez, P., Pichel, V., Laredo, M., Hern\u00e1ndez, A., Freixeiro, F., Sampedro, C., Lorenzo, R., Alcaraz, M., Windisch, M., Cacabelos, R. Oral Cerebrolysin potentiates brain alpha activity and improves memory in elderly humans. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 197 (2000).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Lozano, R., Secades, J., Cacabelos, R. Citicoline protects hippocampal neurons against apoptosis induced by brain \uf062-amyloid deposits plus cerebral hypoperfusion in rats. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 198 (2000).<\/p>\n

\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Double-blind, randomized, placebo-controlled pilot study with anapsos in senile dementia: Effects on cognition, brain electrical activity and cerebral hemodynamics. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 198 (2000).<\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Laredo, M., Couceiro, V., Anido, R., P\u00e9rez, P., Pichel, V., Corzo, L., Zas, R., Alcaraz, M., Garc\u00eda, M., Rodr\u00edguez, S., Freixeiro, F., Figueroa, J., Hern\u00e1ndez, M.A., Lombardi, V., Fern\u00e1ndez-Novoa, L. Cognitive performance in dementia patients during a 4-year follow-up with a neuroprotective multifactorial treatment: Comparative effects for prevention in subjects at risk. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 201 (2000).<\/p>\n

Cacabelos, R., Moreno, A., Caama\u00f1o, J.M., L\u00f3pez, S., P\u00e9rez, P., Pichel, V., Laredo, M., Couceiro, V., Anido, R., Corzo, L., Zas, R., Alcaraz, M., Rodr\u00edguez, S., Hern\u00e1ndez, M.A., \u00c1lvarez, X.A., Lombardi, V., Fern\u00e1ndez-Novoa, L. Cognitive function and brain atrophy in dementia: A psychomorphometric correlation analysis. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 202 (2000).<\/p>\n

de Olano, M., Fern\u00e1ndez-Novoa, L., Mesa, M.D., Corzo, L., Cacabelos, R. Different allele frequency distribution in angiotensin-converting enzyme I\/D polymorphism and angiotensinogen M235T polymorphism in dementia. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 205 (2000).<\/p>\n

Fern\u00e1ndez-Novoa, L., De Olano, M., Mesa, M.D., Cacabelos, R. Alpha-2 macroglobulin V1000I and insertion-deletion polymorphisms in Alzheimer\u2019s disease. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 208 (2000).<\/p>\n

Fern\u00e1ndez-Novoa, L., de Olano, M., Mesa, M.D., Corzo, L., Lombardi, V., \u00c1lvarez, X.A., Cacabelos, R. Identification of two novel mutations in the amyloid precursor protein (APP) gene. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 208 (2000).<\/p>\n

Lombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Sampedro, C., De Olano, M., \u00c1lvarez, X.A., Cacabelos, R. Overexpression of FAS\/CD95 in spontaneous and induced apoptosis in lymphocytes from Alzheimer\u2019s disease patients. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 217 (2000).<\/p>\n

Cacabelos, R. Review of research in geriatric psychiatry. American Society of Hispanic Psychiatry and University of Chicago of Illinois at Chicago. Hispanic American Day at the APA Annual Meeting. May 13 (2000).<\/p>\n

\u00c1lvarez, X.A., Lombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Garc\u00eda, M., Sampedro, C., Cagiao, A., Windisch, M., Moessler, H., Cacabelos, R. Cerebrolysin reduces microglia activation in vivo and in vitro: A potential neuroprotection mechanism. Neuroinflammation in Alzheimer\u2019s Disease. A Neurobiology of Aging Conference. Washington DC, 7-8 July, pp. 2.06 (2000).<\/p>\n

Lombardi, V.R.M., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Garc\u00eda, M., Sampedro, C., de Olano, M., Cacabelos, R. Regulation of brain immunity: A central role played by \uf062-amyloid and IL-1\uf062 in microglial cells. Neuroinflammation in Alzheimer\u2019s Disease. A Neurobiology of Aging Conference. Washington DC, 7-8 July, pp. 2.07 (2000).<\/p>\n

Lombardi, V.R.M., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., de Olano, M., Corzo, L., Sampedro, C., Cacabelos, R. One year \u201cplateau-phase\u201d in microglial cell cultures. Neuroinflammation in Alzheimer\u2019s Disease. A Neurobiology of Aging Conference. Washington DC, 7-8 July, pp. 2.08 (2000).<\/p>\n

Cacabelos, R., Sampedro, C., \u00c1lvarez, X.A. Citicoline exerts antiapoptotic effects in an animal model of hippocampal neurodegeneration. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S87 (2000).<\/p>\n

Lombardi, V., Cacabelos, R., P\u00e9rez, P., Laredo, M., Moessler, H., Hern\u00e1ndez, A., Windisch, M., \u00c1lvarez, X.A. Cerebrolysin improves memory performance and the brain bioelectrical activity pattern in elderly humans. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S157 (2000).<\/p>\n

\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Dose-dependent effects of Anapsos in senile dementia patients: A double-blind, randomized, placebo-controlled study. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S218 (2000).<\/p>\n

Mesa, M.D., Fern\u00e1ndez-Novoa, L., de Olano, M., Cacabelos, R. Allele frequency of alpha-2 macroglobulin V1000I and insertion-deletion polymorphism in Alzheimer\u2019s disease patients. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S250 (2000).<\/p>\n

Fern\u00e1ndez-Novoa, L., Mesa, M.D., Corzo, L., de Olano, M., Cacabelos, R. Two novel mutations in the amyloid precursor protein (APP) gene. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S250 (2000).<\/p>\n

De Olano, M., Fern\u00e1ndez-Novoa, L., Mesa, M.D., Corzo, L., Cacabelos, R. Angiotensin-converting enzyme I\/D polymorphism and ansiotensinogen M235T polymorphism in dementia: A genetic study. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S250 (2000).<\/p>\n

Lombardi, V.R.M., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., de Olano, M., Perea, L., Daniele, D., Cacabelos, R. Regulation of MHC class-I and class-II expression and neuronal death by citicoline. IV European Meeting on Glial Cell Function in Health and Disease. Barcelona, 24-27 May, pp. 100 (2000).<\/p>\n

Lombardi, V.R.M., \u00c1lvarez, X.A., Sampedro, C., Miguel-Hidalgo, J.J., Quack, G., Cacabelos, R. Modulation of A\uf062(1-40)-induced neurodegeneration in the CA1 subfield by memantine. IV European Meeting on Glial Cell Function in Health and Disease. Barcelona, 24-27 May, pp. 100 (2000).<\/p>\n

Lombardi, V.R.M., \u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Cerebrolysin-regulated microglial function through the modulation of proinflammatory cytokines. IV European Meeting on Glial Cell Function in Health and Disease. Barcelona, 24-27 May, pp. 107 (2000).<\/p>\n

\u00c1lvarez, X.A., de Olano, M., Sampedro, C., Lombardi, V., Moessler, H., Windisch, M., Cacabelos, R. Cerebrolysin protects against neurodegeneration induced by \uf062-amyloid in rats. XXIInd CINP Congress, Brussels, 9-13 July, pp. S359 (2000).<\/p>\n

\u00c1lvarez, X.A., Lombardi, V.R.M., Corzo, L., Zas, R., P\u00e9rez, P., Pichel, V., Laredo, M., Hern\u00e1ndez, A., Freixeiro, F., Sampedro, C., Lorenzo, R., Alcaraz, M., Moessler, H., Windisch, M., Cacabelos, R. Oral Cerebrolysin accelerates the brain bioelectrical activity pattern and enhances memory performance in elderly humans. XXIInd CINP Congress, Brussels, 9-13 July, pp. S359 (2000).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Lozano, R., Secades, J., Cacabelos, R. Citicoline protects neurons against apoptosis induced by deposits of \uf062-amyloid into the hippocampus plus cerebral hypoperfusion in rats. XXIInd CINP Congress, Brussels, 9-13 July, pp. S359 (2000).<\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Mesa, M., Olano, M., Laredo, M., Pichel, V., P\u00e9rez, P., Corzo, L., Lombardi, V. Genotype-related therapeutic response in Alzheimer\u2019s disease: A pharmacogenomic approach. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 31 (2000).<\/p>\n

\u00c1lvarez, X.A., Lombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Garc\u00eda, M., Sampedro, C., Cagiao, A., Windisch, M., Moessler, H., Cacabelos, R. Cerebrolysin reduces microglia activation in vivo and in vitro. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 177 (2000).<\/p>\n

\u00c1lvarez, X.A., Lombardi, V., Corzo, L., P\u00e9rez, P., Pichel, V., Laredo, M., Hern\u00e1ndez, A., Freixeiro, F., Sampedro, C., Lorenzo, R., Alcaraz, M., Windisch, M., Moessler, H., Cacabelos, R. Cerebrolysin improves memory and induces brain bioelectrical activation in elderly humans after a single oral administration. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 177 (2000).<\/p>\n

\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Corzo, D., Zas, R., Fern\u00e1ndez-Novoa, L., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Effects of anapsos on cognition, brain bioelectrical activity and cerebral hemodynamics in senile dementia: A double-blind, randomized, placebo-controlled study. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 125 (2000).<\/p>\n

\u00c1lvarez, X.A., Mouzo, R., Pichel, V., P\u00e9rez, P., Laredo, M., Fern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., Alcaraz, M., Secades, J.J., Lozano, R., Cacabelos, R. Effects of citicoline on cognitive performance, brain bioelectrical activity and cerebral perfusion in APOE-genotyped Alzheimer\u2019s disease patients. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 176 (2000).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Lozano, R., Secades, J., Cacabelos, R. Neuroprotective and antiapoptotic effects of citicoline in rats with hippocampal degeneration induced by \uf062-amyloid and hypoperfusion. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 176 (2000).<\/p>\n

\u00c1lvarez, X.A., Miguel-Hidalgo, J.J., Quack, G., Cacabelos, R. Memantine protects against neuronal degeneration induced by A\uf062(1-40) in the CA1 subfield of the rat hippocampus. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 176 (2000).<\/p>\n

Fern\u00e1ndez-Novoa, L., de Olano, M., Mesa, M.D., Cacabelos, R. Alpha-2 macroglobulin polymorphism in Alzheimer\u2019s disease. Eighth World Congress of Psychiatric Genetics. Versailles, 27-31 August, pp. 522 (2000).<\/p>\n

de Olano, M., Fern\u00e1ndez-Novoa, L., Mesa, M.D., Corzo, L., Cacabelos, R. Association between ACE I\/D and APOE polymorphisms in different kinds of dementia. Eighth World Congress of Psychiatric Genetics. Versailles, 27-31 August, pp. 522 (2000).<\/p>\n

Fern\u00e1ndez-Novoa, L., de Olano, M., Mesa, M.D., Corzo, L., Cacabelos, R. Identification of two novel mutations in the amyloid precursor protein (APP) gene. Eighth World Congress of Psychiatric Genetics. Versailles, 27-31 August, pp. 522 (2000).<\/p>\n

Cacabelos, R., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Mesa, M.D., Olano, M., Laredo, M., Pichel, V., P\u00e9rez, P., Corzo, L., Lombardi, V. A pharmacogenomic approach to Alzheimer disease treatment. Eighth World Congress of Psychiatric Genetics. Versailles, 27-31 August, pp. 541 (2000).<\/p>\n

Cacabelos, R. Hipertensi\u00f3n y demencia. VII Congreso de la Sociedad Gallega de Hipertensi\u00f3n Arterial. Sada, La Coru\u00f1a, Sept. 8-9 (2000).<\/p>\n

Corzo, L., \u00c1lvarez, X.A., Zas, R., Rodr\u00edguez, S., P\u00e9rez, P., Cacabelos, R. Niveles de tensi\u00f3n arterial, l\u00edpidos y glucosa en pacientes con demencia senil: Estudio de correlaci\u00f3n. VII Congreso de la Sociedad Gallega de Hipertensi\u00f3n Arterial. Sada, La Coru\u00f1a, Sept. 8-9, pp. 596 (2000).<\/p>\n

\u00c1lvarez, X.A., Mouzo, R., Pichel, V., Laredo, M., P\u00e9rez, P., Couceiro, V., Corzo, L., Zas, R., Varela, M., Sampedro, C., Fern\u00e1ndez-Novoa, L., Mesa, M.D., De Olano, M., Cacabelos, R. Tensi\u00f3n arterial y genotipo apolipoprote\u00edna E (APOE) en la demencia senil. VII Congreso de la Sociedad Gallega de Hipertensi\u00f3n Arterial. Sada, La Coru\u00f1a, Sept. 8-9, pp. 600 (2000).<\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., de Olano, M., Cacabelos, R. Estudio de los polimorfismos de los genes ECA y AGT en demencia e hipertensi\u00f3n arterial. VII Congreso de la Sociedad Gallega de Hipertensi\u00f3n Arterial. Sada, La Coru\u00f1a, Sept. 8-9, pp. 600 (2000).<\/p>\n

Cacabelos, R. Update in Alzheimer therapeutics. Simposio Pfizer CNS. Demencia hoje\u2026 o olhar no futuro. Funchal, Madeira, Portugal. 23 Sept. (2000).<\/p>\n

Cacabelos, R. Gen\u00e9tica de la esquizofrenia y s\u00edndrome psic\u00f3tico. XVIII Congreso Venezolano de Psiquiatr\u00eda \u201cDr. Mauro Villegas\u201d. Psiquiatr\u00eda del Nuevo Milenio. Hotel Radisson Plaza Eurobuilding, Caracas, 18-21 Octubre 2000.<\/p>\n

Cacabelos, R. Farmacogen\u00e9tica de la enfermedad de Alzheimer. XVIII Congreso Venezolano de Psiquiatr\u00eda \u201cDr. Mauro Villegas\u201d. Psiquiatr\u00eda del Nuevo Milenio. Hotel Radisson Plaza Eurobuilding, Caracas, 18-21 Octubre 2000.<\/p>\n

Cacabelos, R. Gen\u00f3mica: Repercusiones diagn\u00f3sticas y terap\u00e9uticas. Simposio Internacional. Hacia una Sociedad Gerontol\u00f3gico. Universidad de Oviedo y Fundaci\u00f3n Ram\u00f3n Areces, Oviedo, 21-22 Noviembre, 2000.<\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Lombardi, V. Distribution of polygenic genotypes in Alzheimer disease (AD): Genomic screening of AD-associated genes. Eur. Neuropsychopharmacol., 11(Suppl.1):S15 (2001).<\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Lombardi, V. Pharmacogenomic studies in Alzheimer disease with a multifactorial treatment. Eur. Neuropsychopharmacol., 11(Suppl.1):S15 (2001).<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V., P\u00e9rez-Herrera, S., Cacabelos, R. Angiotensin-converting enzyme I\/D polymorphism in polygenic disorders. Eur. Neuropsychopharmacol., 11(Suppl.1):S16 (2001).<\/p>\n

Izasa, C., Henao, J., L\u00f3pez, A.M., Cacabelos, R. CYP2D6 allelic variants in the Colombian population. Eur. Neuropsychopharmacol., 11(Suppl.1):S16 (2001).<\/p>\n

Cacabelos, R. Innovaci\u00f3n biotecnol\u00f3xica e iniciativa empresarial. GALIEMPREGO 2001. III Feira da Formaci\u00f3n e o Emprego. Xunta de Galicia, Santiago de Compostela, 15-17 Mayo, 2001.<\/p>\n

Cacabelos, R. Immune function, cytokines and apoptosis in Alzheimer disease: Implications for drug monitoring and pharmacogenomics. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; A-5-4, pp. 13 (2001).<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V., \u00c1lvarez, X.A., Corzo, L., P\u00e9rez-Herrera, S., Sampedro, C., Zas, R., Cacabelos, R. Alpha 2-macroglobulin polymorphisms in early- and late-onset Alzheimer\u2019s disease. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-15, pp. 39 (2001).<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V., \u00c1lvarez, X.A., Corzo, L., P\u00e9rez-Herrera, S., Sampedro, C., Zas, C., Cacabelos, R. Angiotensin-converting enzyme I\/D polymorphism in multifactorial human diseases. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-16, pp. 39 (2001).<\/p>\n

Laredo, M., Couceiro, V., P\u00e9rez, P., \u00c1lvarez, X.A., Cacabelos, R. Senile Dementia-Associated Sleep Disorders Scale (SDASDS). New data on the validation of the Sleep-Related Subscale. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-31, pp. 43 (2001).<\/p>\n

P\u00e9rez, P., Laredo, M., \u00c1lvarez, X.A., Cacabelos, R. Fronto-temporal brain bioelectrical activity theta correlates with hallucinations in Alzheimer disease. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-32, pp. 43 (2001).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Lozano, R., Secades, J., Cacabelos, R. Citicoline reduces neuronal degeneration and apoptosis induced by \uf062-amyloid and hypoperfusion in rats. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-51, pp. 48 (2001).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Lombardi, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R., Moessler, H., Windisch, M. Procognitive, immunomodulatory and neurotrophic activities of Cerebrolysin in an animal model of hippocampal degeneration. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-55, pp. 49 (2001).<\/p>\n

Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Lombardi, V., Cacabelos, R. Vitamin B12 and folate deficiency in dementia. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-06, pp. 93 (2001).<\/p>\n

Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Lombardi, V., Cacabelos, R. Thyroid function study in dementia. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-07, pp. 93 (2001).<\/p>\n

\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Fern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., Alcaraz, M., Sampedro, C., Cacabelos, R., Secades, J., Lozano, R. Citicoline improves cognitive performance, brain bioelectrical activity and cerebral perfusion in APOE-genotyped Alzheimer disease patients. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-26, pp. 98 (2001).<\/p>\n

\u00c1lvarez, X.A., Lombardi, V., Corzo, L., P\u00e9rez, P., Pichel, V., Laredo, M., Hern\u00e1ndez, A., Freixeiro, F., Varela, M., Sampedro, C., Alcaraz, M., Rodr\u00edguez, S., Cacabelos, R., Windisch, M., Moessler, H. Oral Cerebrolysin in elderly humans: Effects on memory and brain bioelctrical activity. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-27, pp. 98 (2001).<\/p>\n

\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Corzo, D., Sampedro, C., Zas, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R., Sempere, J.M., D\u00edaz, J. Procognitive and neurobiological effects of anapsos in senile dementia: A double-blind and placebo-controlled study. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-28, pp. 98 (2001).<\/p>\n

Lombardi, V.R.M., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Corzo, L., Zas, R., Cacabelos, R. Peripheral immune dysfunction in Alzheimer disease. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-37, pp. 100 (2001).<\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Corzo, L., Laredo, M., P\u00e9rez, P., Pichel, V., Lombardi, V. Multifactorial treatment and pharmacogenomics in Alzheimer disease. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-46, pp. 103 (2001).<\/p>\n

Cacabelos, R. Psychogeriatric research: Strategies and development. 16th Jap. Congr. Psychogeriatrics. Osaka, 13-15 June, 2001.<\/p>\n

Cacabelos, R. Prospective treatments in Alzheimer disease. 16th Jap. Congr. Psychogeriatrics. Osaka, 13-15 June, 2001.<\/p>\n

Cacabelos, R. Family, work and health. First CEDE International Congress of Directors. Enterpreneurs with values: Directors and the new Europe-America partnership. Madrid Nov. 29-30 (2002).<\/p>\n

Cacabelos, R. Genomics: Implications for diagnosis and treatment. Aging at XXI century. Thinking the future. Coimbra University Hospitals, Coimbra, 21-23 March, 2002.<\/p>\n

Cacabelos, R. Workshop \u201cMild Cognitive Impairment: Concept and Realities\u201d. Divonne-les-Bains, France, April 1-2, 2002.<\/p>\n

Cacabelos, R. Pharmacogenomics and treatment of Alzheimer disease. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 39, 2002.<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Antiapoptotic and neuroprotective effects of anapsos in rats with beta-amyloid injections into the hippocampus. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 161, 2002.<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., P\u00e9rez, P., Pichel, V., Hern\u00e1ndez, A., Varela, M., Figueroa, J., Laredo, M., Couceiro, V., Corzo, L., Moessler, H., Cacabelos, R. Positive effects of cerebrolysin on brain bioelectrical activity and cognitive performance in traumatic brain injury and in senile dementia patients. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 162, 2002.<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Fondevila, M., Seoane, S., Cacabelos, R. Prion protein gene (PRNP) polymorphisms in Alzheimer disease. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 183, 2002.<\/p>\n

Lombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Cacabelos, R. Cytokine production by human peripheral blood mononuclear cells in Alzheimer disease. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 212, 2002.<\/p>\n

Pichel, V., P\u00e9rez, P., Fern\u00e1ndez-Novoa, L., Laredo, M., Couceiro, V., Alcaraz, M., Rodr\u00edguez, S., Mulet, E., Cacabelos, R. Cerebrovascular risk factors and hemodynamics in dementia. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 228, 2002.<\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, P., Laredo, M., Couceiro, V., Pichel, V., \u00c1lvarez, A. Alzheimer Disease-Associated Genes: Genomic Screening in the Spanish Population. Proceedings ELSO 2002, Nice, France, June 29-July 3, pp. 20 (2002).<\/p>\n

Lombardi, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Evaluation of TNF-alpha and IL-10 levels in peripheral blood mononuclear cells of Alzheimer patients measured by a cytometric bead array system. Proceedings ELSO 2002, Nice, France, June 29-July 3, pp. 281 (2002).<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V., Cacabelos, R. Association studies of polymorphisms in the angiotensin converting enzyme gene (ACE) and Alzheimer\u2019s disease (AD) in the Spanish population. Proceedings ELSO 2002, Nice, France, June 29-July 3, pp. 294 (2002).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Fern\u00e1ndez-Novoa, L., Lombardi, V., Cacabelos, R. Amyloid beta-induced neurodegeneration in vivo: An experimental model to test potential anti-dementia drugs. Proceedings ELSO 2002, Nice, France, June 29-July 3, pp. 308 (2002).<\/p>\n

\u00c1lvarez, A., Cacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V. Pharmacogenomics and treatment of Alzheimer\u2019s disease. XXIIIrd CINP Congress, June 23-27, Montr\u00e9al, Canada, P.1.W.071. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S90 (2002).<\/p>\n

\u00c1lvarez, A., Fern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Fondevila, M., Seoane, S., Cacabelos, R. M129V polymorphism at the PRNP gene and Alzheimer\u2019s disease in the Spanish population. XXIIIrd CINP Congress, June 23-27, Montr\u00e9al, Canada, P.2.E.098. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S118 (2002).<\/p>\n

\u00c1lvarez, A., Cacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V., P\u00e9rez, P., Laredo, M., Couceiro, V., Alcaraz, M., Rodr\u00edguez, S., Sampedro, C., Pichel, V. Genomic screening of Alzheimer\u2019s disease-associated genes in the Spanish population. XXIIIrd CINP Congress, June 23-27, Montr\u00e9al, Canada, P.2.E.095. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S117 (2002).<\/p>\n

\u00c1lvarez, A., Cacabelos, R., Pichel, V., P\u00e9rez, P., Fern\u00e1ndez-Novoa, L., Laredo, M., Couceiro, V., Alcaraz, M., Rodr\u00edguez, S., Mulet, E., Sampedro, C., Lombardi, V. Cerebrovascular risk factors and hemodynamics in dementia. XXIIIrd CINP Congress, June 23-27, Montr\u00e9al, Canada, P.1.W.067. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S89 (2002).<\/p>\n

\u00c1lvarez, A., Sampedro, C., P\u00e9rez, P., Pichel, V., Hern\u00e1ndez, A., Varela, M., Figueroa, J., Laredo, M., Couceiro, V., Corzo, L., Moessler, H., Cacabelos, R. Cerebrolysin improves brain bioelectrical activity pattern and cognitive functioning in traumatic brain injury and in senile dementia. XXIIIrd CINP Congress, June 23-27, Montreal, Canada, P.1.W.081. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S92 (2002).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Central beta-amyloid impairs learning and induces neuronal degeneration and apoptosis in rats: Neuroprotective effects of Anapsos. XXIIIrd CINP Congress, June 23-27, Montreal, Canada, P.3.W.084. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S177 (2002).<\/p>\n

Cacabelos, R. Avances en biolog\u00eda molecular, gen\u00e9tica y neuroqu\u00edmica de la esquizofrenia. II International Congress ARAPDIS & IX Congress Mediterranean Social Psychiatrie (MESPA), Barcelona, May 26-30 (2002).<\/p>\n

Cacabelos, R., Artigas, F., Fa\u00f1anas, L., Bulbena, A., Taboada, A. Bases etiopatog\u00e9nicas de la esquizofrenia: Gen\u00e9tica, biolog\u00eda molecular, neuroqu\u00edmica y neurofarmacolog\u00eda. II International Congress ARAPDIS & IX Congress Mediterranean Social Psychiatrie (MESPA), Barcelona, May 26-30 (2002).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Anapsos reverses the neurotoxic effects of central beta-amyloid injections in rats: Behavioral and morphological evaluations. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S97 (2002).<\/p>\n

Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R., Quack, G. Memantine prevents beta-amyloid-induced neurotoxicity and learning impairment in rats. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S102 (2002).<\/p>\n

Cacabelos, R., \u00c1lvarez, A., P\u00e9rez, P., Laredo, M., Couceiro, V., Alcaraz, M., Rodr\u00edguez, S., Pichel, V. Multifactorial therapy in vascular dementia and Alzheimer disease. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S121 (2002).<\/p>\n

Lombardi, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Increased TNF-alpha and IL-10 production by human peripheral blood mononuclear cells in Alzheimer\u2019s disease measured by a cytometric bead array system. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S229 (2002).<\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V., P\u00e9rez, P., Laredo, M., Couceiro, V., Alcaraz, M., Rodr\u00edguez, S., Pichel, V., \u00c1lvarez, A. Genomic screening of Alzheimer\u2019s disease-associated genes in the Spanish population. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S318 (2002).<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V., Seoane, S., Cacabelos, R. M129V polymorphism at the PRNP gene in Alzheimer\u2019s disease. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S320 (2002).<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V., Seoane, S., Cacabelos, R. Angiotensin converting enzyme gene polymorphism (ACE) and Alzheimer\u2019s disease (AD) in the Spanish population. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S346 (2002).<\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V., Takeda, M. Genomic variation and pharmacogenomic studies in Alzheimer disease. XII World Congress of Psychiatry. Yokohama, August 24-29, pp. 111 (2002).<\/p>\n

Takeda, M., Cacabelos, R., Ray, O., Forstl, H., Hoon Oh, B. International situation of diagnosing dementia and the direction of future study. Cognition and Dementia. Round Table Discussion. Yokohama, August 27 (2002).<\/p>\n

Cacabelos, R. Genomic screening, genetic variation and pharmacogenomics in Alzheimer disease. International Symposium \u201cMolecular Neurobiology of Alzheimer Disease and Related Disorders\u201d. Osaka Sun Palace Hotel, Osaka, October 5; Dementia Japan 16:83 (2002).<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V., Seoane, S., Cacabelos, R. Distribution of APOE genotypes in CNS disorders in the Spanish population. Am. J. Med. Genet., 114\/7:789 (2002).<\/p>\n

Cacabelos, R., Lombardi, V., Fern\u00e1ndez-Novoa, L. Genomic variation in Alzheimer disease. Am. J. Med. Genet., 114\/7:829 (2002).<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Fondevila, M., Seoane, S., Cacabelos, R. Association study of M129V polymorphism at the PRNP gene in Alzheimer disease. Am. J. Med. Genet., 114\/7:829-830 (2002).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Cacabelos, R. Effects of central beta-amyloid on learning, glial activation, neuronal degeneration and apoptosis in rats. 6th Congress of the European Federation of Neurological Societies. Vienna, October 26-29, 2002. Eur. J. Neurol., 9(Suppl.2):158-159 (2002).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Corzo, L., P\u00e9rez, P., Pichel, V., Laredo, M., Hern\u00e1ndez, A., Varela, M., Figueroa, J., Cacabelos, R., Windisch, M., Moessler, H. . 6th Congress of the European Federation of Neurological Societies. Vienna, October 26-29, 2002. Eur. J. Neurol., 9(Suppl.2):198 (2002).<\/p>\n

Cacabelos, R. Foro de nuevas bioempresas. EBIOTEC. BioSpain\/Asebio-2003. Madrid, 23-28 Feb. (2003).<\/p>\n

Cacabelos, R. Genetic variation and pharmacogenomic profiles in Alzheimer disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 3.<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Central amyloid-beta impairs learning and induces glial activation, neuronal loss and apoptosis in rats. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 16.<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R., Windisch, M. AF64A-induced neuronal apoptosis in the septohippocampal area. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 17.<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R., Sempere, J.M., D\u00edaz, J. Anapsos reverses beta-amyloid-induced learning impairment, neuronal loss and apoptosis. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 17.<\/p>\n

Amado, L., Etcheverr\u00eda, I., Pichel, V., Moreno, A., Cacabelos, R. Age-dependent changes in brain atrophy parameters. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 17.<\/p>\n

Amado, L., Etcheverr\u00eda, I., Pichel, V., Moreno, A., Corzo, L., Zas, R., Lombardi, V., Cacabelos, R. Influence of vascular risk factors on brain atrophy. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 17.<\/p>\n

Lombardi, V.R.M., D\u00edaz, J., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Blanco, A., Cacabelos, R. Regulation of MHC class-I and class-II expression on primary microglial cells by natural compounds. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 28.<\/p>\n

Pichel, V., Amado, L., Etcheverr\u00eda, I., Cacabelos, R. Age-dependent cerebrovascular hemodynamic changes. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 33.<\/p>\n

Pichel, V., Amado, L., Etcheverr\u00eda, I., Corzo, L., Zas, R., Alcaraz, M., Mulet, E., Rodr\u00edguez, S., Cacabelos, R. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 33.<\/p>\n

Pichel, V., Figueroa, J., Cornes, J.M., \u00c1lvarez, X.A., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Amado, L., Hern\u00e1ndez, A., Varela, M., Cacabelos, R. Cervico-arthrosis is associated with occipital EEG slowing and a poor brain perfusion in women. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 34.<\/p>\n

Aguilar-Aldrete, M.E., Cacabelos, R., Rosales-G\u00f3mez, R.C., Rodr\u00edguez-Vera, M.C., Silva-Lepe, Y., Moran-Moguel, M.C. The apolipoprotein E genotype in western Mexican population with Alzheimer disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 54.<\/p>\n

\u00c1lvarez, X.A., Lombardi, V., Sampedro, C., Corzo, L., Zas, R., P\u00e9rez, P., Laredo, M., Cruceiro, V., Astoreka, I., Varela, M., Fern\u00e1ndez-Novoa, L., Cacabelos, R., Stoeffler, A., Moebius, H.J. Genotype-related reduction of apoptosis in Alzheimer\u2019s disease patients treated with memantine. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 54.<\/p>\n

Isaza, C., Henao, J., Fern\u00e1ndez-Novoa, L., Cacabelos, R. The drug metabolizer CYP2D6 gene in Alzheimer disease therapy. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 56.<\/p>\n

Etcheverr\u00eda, I., Pichel, V., Amado, L., Fern\u00e1ndez-Novoa, L., Lombardi, V., Cacabelos, R. APOE genotype-related brain atrophy in the Spanish population. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 57.<\/p>\n

Etcheverr\u00eda, I., Pichel, V., Amado, L., Fern\u00e1ndez-Novoa, L., Alcaraz, M., Mulet, E., Rodr\u00edguez, S., Cacabelos, R. APOE-related cerebrovascular hemodynamics in the Spanish population. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 57.<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Corzo, L., Laredo, M., Cruceiro, V., \u00c1lvarez, X.A., Cacabelos, R. Association study between DCPI genotype and Alzheimer\u2019s disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 58.<\/p>\n

Kubota, Y., Pichel, V., Fern\u00e1ndez-Novoa, L., Lombardi, V., \u00c1lvarez, A., Mollet, E., Alcaraz, M., Rodr\u00edguez, S., Laredo, M., Cruceiro, V., Amado, L., Etcheverr\u00eda, I., Cacabelos, R. Combination therapy in Alzheimer disease: A pharmacogenomic study. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 64.<\/p>\n

Laredo, M., Couceiro, V., Fraile, C., \u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Neuropsychological evaluation of mild degenerative dementia patients: improving the screening capacity of the MMSE. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 65.<\/p>\n

Pichel, V., Etcheverr\u00eda, I., Amado, L., Cacabelos, R. Effect of cerebrovascular risk factors on brain hemodynamics in dementia. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 73.<\/p>\n

Lombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Cacabelos, R. Regulating factors for pathological activation of microglia in Alzheimer\u2019s disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 121.<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Corzo, L., Zas, R., P\u00e9rez, P., Pichel, V., Laredo, M., Cruceiro, V., Hern\u00e1ndez, A., Varela, M., Figueroa, J., Lombardi, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R., Moessler, H. Cerebrolysin improves cognition and brain bioelectrical activity in senile dementia and in traumatic brain injury patients. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 126.<\/p>\n

Cacabelos, R., Kubota, Y., Pichel, V., Lombardi, V., Mollet, E., Alcaraz, M., Rodr\u00edguez, S., Amado, L., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Su\u00e1rez, J., Pardo, R. E-SAR-94010: A novel pleiotropic compound with age-dependent regulatory activity on lipid metabolism. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 127.<\/p>\n

Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. FERUM nitric oxide study in Alzheimer disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 128.<\/p>\n

Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Laredo, M., Cruceiro, V., Sampedro, C., Rodr\u00edguez, S., Cacabelos, R. Study of serum apolipoprotein E in Alzheimer disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 128.<\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., Seoane, S., Zas, R., Sampedro, C., \u00c1lvarez, X.A., Lombardi, V.R.M., Cacabelos, R. ACE serum activity and I\/D genetic polymorphism in elderly subjects. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 129.<\/p>\n

Lombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Cacabelos, R. Flow cytometry analysis of supressor cell precursor and memory T lymphocytes in the peripheral blood of Alzheimer\u2019s disease patients. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 131.<\/p>\n

Takeda, M., Cacabelos, R. (Co-chairmen), Yamada, T., Maelick, A., Kurz, A. Roundtable Discussion Meeting on Treatment for Patients with Dementia. Sal\u00f3n Lebrija. Hotel Meli\u00e1 Sevilla, May 12, 2003.<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Laredo, M., Cruceiro, V., Fern\u00e1ndez-Novoa, L., Kubota, Y., Cacabelos, R., Vargas, M. Differential influence of neuropsychiatric symptoms on functional and cognitive decline in mild-moderate Alzheimer\u2019s disease. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 41. <\/p>\n

Isaza, C., Henao, J., Fern\u00e1ndez-Novoa, L., Kubota, Y., Cacabelos, R. The drug metabolizer CYP2D6 in Alzheimer\u2019s disease. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 42.<\/p>\n

Lombardi, V., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Kubota, Y., Cacabelos, R. Peripheral blood analysis of CD28-\/CD8+ supressor cell precursor and CD45RO+\/CD4+ memory T-lymphocytes in patients with Alzheimer\u2019s disease. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 42. <\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., Seoane, S., Lombardi, V., Kubota, Y., Cacabelos, R. ACE serum activity and ACE genetic polymorphisms in elderly subjects. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 42.<\/p>\n

Amado, L., Etcheverr\u00eda, I., Pichel, V., Kubota, Y., Cacabelos, R. Age-dependent brain atrophy in CNS disorders: A CT-Scan study. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 42-43. <\/p>\n

Etcheverr\u00eda, I., Pichel, V., Amado, L., Fern\u00e1ndez-Novoa, L., Kubota, Y., Cacabelos, R. Differential brain atrophy profile associated with APOE genotype in CNS disorders. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 43.<\/p>\n

Pichel, V., Amado, L., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Kubota, Y., Cacabelos, R. APOE-related cerebrovascular risk factors and hemodynamics in CNS disorders. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 43. <\/p>\n

Etcheverr\u00eda, I., Amado, L., Pichel, V., Cacabelos, R. Age- and APOE-dependent cerebrovascular changes in the Spanish population. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 32.<\/p>\n

Pichel, V., Amado, L., Etcheverr\u00eda, I., Cacabelos, R. Age-dependent changes in brain hemodynamic parameters. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 38.<\/p>\n

Etcheverr\u00eda, I., Amado, L., Pichel, V., Cacabelos, R. Age-dependent brain atrophy: A CT-Scan study. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 47.<\/p>\n

Etcheverr\u00eda, I., Amado, L., Pichel, V., Cacabelos, R. Differential brain atrophy profile associated with the APOE genotype in the Spanish population. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 47.<\/p>\n

Pichel, V., Amado, L., Etcheverr\u00eda, I., Cacabelos, R. Vascular risk factors and brain atrophy: A correlation analysis in the Spanish population. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 55.<\/p>\n

Pichel, V., Amado, L., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Laredo, M., Cruceiro, V., Alcaraz, M., Rodr\u00edguez, S., Mulet, E., Cacabelos, R. APOE-related cerebrovascular risk factors and hemodynamics in dementia. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 55.<\/p>\n

Amado, L., Etcheverr\u00eda, I., Pichel, V., Fern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Cacabelos, R. APOE genotype-related brain atrophy in the Spanish population. First Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2003). G\u00f6teborg, 2003; pp. 33.<\/p>\n

Etcheverr\u00eda, I., Pichel, V., Amado, L., Fern\u00e1ndez-Novoa, L., Alcaraz, M., Mulet, E., Rodr\u00edguez, S., Cacabelos, R. APOE-related cerebrovascular hemodynamics in the Spanish population. First Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2003). G\u00f6teborg, 2003; pp. 55.<\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Tellado, I., Kubota, Y., Lombardi, V., Pichel, V.M. APOE-related phenotypic variation in brain bioelectrical activity mapping. First Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2003). G\u00f6teborg, 2003; pp. 58-59.<\/p>\n

Pichel, V., Amado, L., Etcheverr\u00eda, I., Corzo, L., Zas, R., Alcaraz, M., Mulet, E., Rodr\u00edguez, S., Cacabelos, R. Vascular risk factor-associated brain hemodynamics. First Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2003). G\u00f6teborg, 2003; pp. 60-61.<\/p>\n

Cacabelos, R. Potential role of histamine and cytokine networks in Alzheimer disease and neurodegeneration. 1st International Symposium of Neurobehavioral Pharmacology. Okayama, September 13-15, 2003; pp. 72.<\/p>\n

Lombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Chronic activation of immune\/inflammatory cells in Alzheimer\u2019s disease. VI European Meeting on Glial Cell Function in Health and Disease. Berlin, September 3-6, 2003; P-104.<\/p>\n

\u00c1lvarez, X.A., Laredo, M., Cruceiro, V., Fern\u00e1ndez-Novoa, L., Sampedro, C., Cacabelos, R., Vargas, M., Aleixandre, M. Neuropsychiatric symptoms in APOE-genotyped Alzheimer\u2019s disease patients: Contributions to diagnosis and prognosis of the disease. 16th Congress of the European College of Neuropsychopharmacology. Prague, September 20-24, 2003. European Neuropsychopharmacology, 13(Suppl.4):S399-S400 (2003). <\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Laredo, M., Cruceiro, V., P\u00e9rez, P., Cacabelos, R., Moessler, H., Doppler, E. Effects of cerebrolysin on quantitative EEG activity in elderly controls and in patients with brain damage. 16th Congress of the European College of Neuropsychopharmacology. Prague, September 20-24, 2003. European Neuropsychopharmacology, 13(Suppl.4):S400 (2003). <\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Memory deficits and neuropathology induced by central amyloid-beta injections in rats. 16th Congress of the European College of Neuropsychopharmacology. Prague, September 20-24, 2003. European Neuropsychopharmacology, 13(Suppl.4):S405 (2003). <\/p>\n

\u00c1lvarez, X.A., Lombardi, V., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Cacabelos, R. CD28-\/CD8+ supressor cell precursor and CD45RO+\/CD4+ memory T lymphocyte expressions in the peripheral blood of Alzheimer\u2019s disease patients. 16th Congress of the European College of Neuropsychopharmacology. Prague, September 20-24, 2003. European Neuropsychopharmacology, 13(Suppl.4):S406 (2003). <\/p>\n

Pichel, V., Etcheverr\u00eda, I., Amado, L., Kubota, Y., Cacabelos, R. Phenotypic profiles of vascular dementia and Alzheimer disease associated with brain atrophy and cerebrovascular hemodynamics. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 38.<\/p>\n

Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Oxidative and vascular blood markers in dementia. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 43.<\/p>\n

Etcheverr\u00eda, I., Pichel, V., Amado, L., Moreno, A., Cacabelos, R. Brain atrophy-associated vascular risk factors. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 47.<\/p>\n

Etcheverr\u00eda, I., Pichel, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Association between different APOE genotypes and cerebrovascular parameters assessed by transcranial Doppler ultrasonography in the Spanish population. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 47.<\/p>\n

Pichel, V., Etcheverr\u00eda, I., Corzo, L., Zas, R., Cacabelos, R. Effects of vascular risk factors on brain hemodynamic parameters. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 51.<\/p>\n

Pichel, V., Etcheverr\u00eda, I., Cacabelos, R. Age-related cerebrovascular changes in hemodynamic parameters. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 51.<\/p>\n

Etcheverr\u00eda, I., Vallejo, A.I., Lombardi, V.R.M., Corzo, L., Zas, R., Cacabelos, R. Efecto de BioKin sobre par\u00e1metros bioqu\u00edmicos en sangre de ratas con suplementaci\u00f3n diet\u00e9tica. IX Congreso de la Sociedad Espa\u00f1ola de Nutrici\u00f3n. Tenerife, Noviembre 26-29, 2003. Nutrici\u00f3n Hospitalaria, XVIII\/5:296 (2003). <\/p>\n

Vallejo, A.I., Etcheverr\u00eda, I., Lombardi, V.R.M., Cacabelos, R. Efecto de BioKin sobre el crecimiento en ratas. IX Congreso de la Sociedad Espa\u00f1ola de Nutrici\u00f3n. Tenerife, Noviembre 26-29, 2003. Nutrici\u00f3n Hospitalaria, XVIII\/5:297 (2003). <\/p>\n

Vallejo, A.I., Lombardi, V., Fern\u00e1ndez-Novoa, L., Pichel, V., Amado, L., Cacabelos, R. E-SAR-94010 (LipoEsar): Un compuesto lipoproteico pleiotr\u00f3pico con un poderoso efecto anti-ateromatoso e hipolipemiante. IX Congreso de la Sociedad Espa\u00f1ola de Nutrici\u00f3n. Tenerife, Noviembre 26-29, 2003. Nutrici\u00f3n Hospitalaria, XVIII\/5:318 (2003). <\/p>\n

Etcheverr\u00eda, I., Vallejo, A.I., Lombardi, V., Corzo, L., Zas, R., Cacabelos, R. BioKin effects on the blood biochemical parameters of rats with a supplemented diet. Nutrition, 19:1052-1053 (2003).<\/p>\n

Vallejo, A.I., Lombardi, V., Fern\u00e1ndez-Novoa, L., Pichel, V., Amado, L., Cacabelos, R. E-SAR-94010 (LipoEsar): A pleiotropic lipoprotein compound with powerful anti-atheromatous and lipid-lowering effects. Nutrition, 19:1066 (2003).<\/p>\n

Cacabelos, R., Lombardi, V., Kubota, Y., Pichel, V., Fern\u00e1ndez-Novoa, L. Increased genetic variation in Alzheimer disease (AD) and no apparent influence of the prion M129V polymorphism on AD pharmacogenomics. Human Genome Meeting (HGM-2004). Berlin, April 4-7, 2004; pp. 63.<\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., Seoane, S., Cacabelos, R. Influence of ACE indel polymorphism on ACE activity and plasma beta-amyloid in dementia. Human Genome Meeting (HGM-2004). Berlin, April 4-7, 2004; pp. 65.<\/p>\n

Isaza, C., Henao, J., Fern\u00e1ndez-Novoa, L., Cacabelos, R. The drug metabolizer CYP2D6 gene in Alzheimer disease. Human Genome Meeting (HGM-2004). Berlin, April 4-7, 2004; pp. 67.<\/p>\n

Lombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Probable Alzheimer disease and alpha-2-macroglobulin polymorphism. Human Genome Meeting (HGM-2004). Berlin, April 4-7, 2004; pp. 70.<\/p>\n

Tellado, I., Fern\u00e1ndez-Novoa, L., Lombardi, V., Pichel, V., Cacabelos, R. APOE-related phenotypic variation in brain function. Human Genome Meeting (HGM-2004). Berlin, April 4-7, 2004; pp. 75.<\/p>\n

Cacabelos, R. Genetic variation, functional genomics and pharmacogenomics in Alzheimer disease. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004. Neurobiol. Aging, 25:S4 (2004).<\/p>\n

\u00c1lvarez, A., Corzo, L., Sampedro, C., Cacabelos, R. FERUM insulin-like growth factor I (IGF-I), growth hormone (GH), tumor necrosis factor-alpha (TNF) and interleukin-6 (IL6) in Alzheimer disease (AD) and mild cognitive impairment (MCI) patients. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 36.<\/p>\n

\u00c1lvarez, A., Laredo, M., Sampedro, C., Cacabelos, R. Vargas, M., Illescas, I. Prevalence of neuropsychiatric symptoms (NPS) in a clinical population of APOE-genotyped patients: Alzheimer disease (AD) versus mild cognitive impairment. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 37.<\/p>\n

\u00c1lvarez, A., Varela, M., Sampedro, C., Cruceiro, V., Cacabelos, R., Moessler, H. Positive effects of cerebrolysin in Alzheimer disease (AD): a randomized, double-blind, placebo-controlled trial (RCT). 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 38.<\/p>\n

\u00c1lvarez, A., Cacabelos, R., Moessler, H., Doppler, E. Cerebrolysin in moderate to moderately severe Alzheimer disease (AD): Subgroup analysis of a randomized, double-blind, placebo-controlled trial (RCT). 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 39.<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V., Seoane, S., Cacabelos, R. Alpha-2-macroglobulin polymorphisms in probable Alzheimer disease. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 58.<\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., Seoane, S., Cacabelos, R. ACE InDel polymorphism, serum ACE activity and plasma beta-amyloid in dementia. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 59.<\/p>\n

Lombardi, V., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Cellular immune changes in peripheral blood of Alzheimer disease patients. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 85.<\/p>\n

Lombardi, V., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Activation of immune cells in peripheral blood of Alzheimer disease patients. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 86.<\/p>\n

Cacabelos, R. The pathogenic role of histamine in Alzheimer disease. 33rd Annual Meeting European Histamine Research Society. D\u00fcsseldorf\/K\u00f6ln, April 28-May 2, 2004; pp. 30.<\/p>\n

\u00c1lvarez, X.A., Cacabelos, R., Vargas, M., Aleixandre, M., Linares, C., Granizo, E., Moessler, H. Dose-response effects of cerebrolysin in Alzheimer\u2019s disease patients: A randomized, double-blind, placebo-controlled trial. XXIV CINP Congress, June 2004. Int. J. Neuropsychopharmacol., 7(Suppl.1): S383 (2004).<\/p>\n

Lombardi, V., \u00c1lvarez, X.A., Echeverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Alterations in percentages of lymphocyte subpopulations in peripheral blood of Alzheimer\u2019s disease patients. XXIV CINP Congress, June 2004. Int. J. Neuropsychopharmacol., 7(Suppl.1 : S383 (2004).<\/p>\n

\u00c1lvarez, X.A., Laredo, M., Cruceiro, V., Sampedro, C., Cacabelos, R., Illescas, E., Vargas, M., Moessler, H. Frequency and severity of neuropsychiatric symptoms in Alzheimer\u2019s disease and mild cognitive impairment: influence of the APOE genotype. XXIV CINP Congress, June 2004. Int. J. Neuropsychopharmacol., 7(Suppl.1): S384 (2004).<\/p>\n

Cacabelos, R. Gen\u00e9tica y envejecimiento. Congreso Internacional. El Reto del Envejecimiento 1979-2004. 25 A\u00f1os de Atenci\u00f3n Gerontol\u00f3gico en M\u00e9xico. M\u00e9xico DF, 16-18 Junio, 2004.<\/p>\n

Cacabelos, R. Farmacogen\u00f3mica y envejecimiento. Galisenior. 4\u00ba Sal\u00f3n Gallego de Nuestros Mayores. I Foro Europeo sobre Envejecimiento. Orense, 21-23 Octubre, 2004.<\/p>\n

Fern\u00e1ndez-Novoa, L., Seoane, S., Lombardi, V., Cacabelos, R. The influence of genotype on blood lipid parameters in Alzheimer\u2019s disease and control subjects. 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 25 (2005).<\/p>\n

\u00c1lvarez, X.A., Cacabelos, R., Moessler, H. Cerebrolysin: Efficacy and safety in moderate to moderately severe Alzheimer\u2019s disease- A subgroup analysis of a randomized, double-blind, placebo-controlled trial. 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 46 (2005).<\/p>\n

Cacabelos, R. Functional genomics and pharmacogenomics of Alzheimer\u2019s disease. 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 56 (2005).<\/p>\n

\u00c1lvarez, X.A., Corzo, L., Zas, R., Sampedro, C., Cacabelos, R. Serum TNF-alpha in Alzheimer\u2019s disease: Increased levels and negative correlations with IGF-1. 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 120 (2005).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Cruceiro, V., Corzo, L., Cacabelos, R., Aleixandre, M., Vargas, M., Linares, C., Granizo, E., Moessler, H. Double-blind, placebo-controlled study of three doses of cerebrolysin in mild to moderate Alzheimer\u2019s disease. 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 136 (2005).<\/p>\n

Lombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Alterations of immune functions and lymphocyte apoptosis in patients with Alzheimer\u2019s disease (AD). 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 170 (2005).<\/p>\n

Cacabelos, R. Pharmacogenomics studies in Alzheimer\u2019s disease: Genotype-related therapeutic response. Joint Meeting of the 27th Annual Meeting of the Japanese Society of Biological Psychiatry (JSBP) and the 35th Annual Meeting of the Japanese Society of Neuropsychopharmacology (JSNP). Osaka, July 6-8, pp. 15, 2005.<\/p>\n

Cacabelos, R. Pharmacogenetics and pharmacogenomics of CNS disorders. Joint Meeting of the 27th Annual Meeting of the Japanese Society of Biological Psychiatry (JSBP) and the 35th Annual Meeting of the Japanese Society of Neuropsychopharmacology (JSNP). Osaka, July 6-8, pp. 93, 2005.<\/p>\n

\u00c1lvarez, A., Laredo, M., Couceiro, V., Sampedro, C., Cacabelos, R., Illescas, E., Vargas, M. Neuropsychiatric symptoms in Alzheimer\u2019s disease versus mild cognitive impairment. XIII World Congress of Psychiatry, Cairo, Egypt, 10-15 Sept. PO1.P259 (2005).<\/p>\n

\u00c1lvarez, A., Cacabelos, R., Laredo, M., Varela, M., Sampedro, C., Aleixandre, M., Illescas, E., Linares, C., Granizo, E., Moessler, H. Cerebrolysin in Alzheimer\u2019s disease: a double-blind, placebo-controlled study. XIII World Congress of Psychiatry, Cairo, Egypt, 10-15 Sept. OR22.6 (2005).<\/p>\n

\u00c1lvarez, A., Laredo, M., Couceiro, V., Sampedro, C., Cacabelos, R., Illescas, E., Aleixandre, M. Neuropsychiatric symptoms in vascular dementia: Comparison with AD and mild cognitive impairment. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Cruceiro, V., Garc\u00eda, C., Vargas, M., Cuesta, I., Cacabelos, R., Moessler, H. Cognitive improvement and EEG activation by cerebrolysin in vascular dementia: an exploratory study. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).<\/p>\n

Cacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V., Tellado, I., Nebril, L., Casas, A., Alcaraz, M., Pichel, V. Structural genomics studies in vascular dementia (VD) and Alzheimer disease (AD): Differential genomic patterns and genetic variation. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).<\/p>\n

Fern\u00e1ndez-Novoa, L., Seoane, S., Corzo, L., Lombardi, V.R.M., Cacabelos, R. Genetic risk factors and lipid parameters in dementia. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).<\/p>\n

Corzo, L., Fern\u00e1ndez-Novoa, L., Rodr\u00edguez, S., Cacabelos, R. Decreased serum nitric oxide levels in vascular dementia. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).<\/p>\n

Lombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Peripheral increases in IL-6, lymphocyte apoptosis and immune activation in patients with dementia. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).<\/p>\n

Pichel, V., Tellado, I., Nebril, L., Casas, A., Alcaraz, M., Varela, M., Cacabelos, R. Disease-specific differences in brain hemodynamics in patients with vascular dementia, Alzheimer\u2019s disease and Parkinson\u2019s disease. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).<\/p>\n

Tellado, I., Pichel, V., Nebril, L., Casas, A., Alcaraz, M., Varela, M., Cacabelos, R. Influence of blood pressure on brain hemodynamics and bioelectrical activity spectral power in vascular dementia, Alzheimer\u2019s disease and Parkinson\u2019s disease. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).<\/p>\n

Tellado, I., Pichel, V., Cacabelos, R. Brain bioelectrical activity spectral power in vascular dementia, Alzheimer\u2019s disease and Parkinson\u2019s disease. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).<\/p>\n

Pichel, V., Tellado, I., Nebril, L., Casas, A., Alcaraz, M., Varela, M., Cacabelos, R. Age-related brain hemodynamics in vascular dementia, Alzheimer\u2019s disease and Parkinson\u2019s disease. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).<\/p>\n

Cacabelos, R. Pharmacogenetic aspects of therapy with cholinesterase inhibitors. 9th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. 19-22 April, Geneva, Neurobiol. Aging, 27 (S1): S4 (2006).<\/p>\n

\u00c1lvarez, A., Laredo, M., Varela, M., Cacabelos, R., Sampedro, C., Aleixandre, M., Linares, C., Moessler, H. Double-blind, placebo-controlled study of three different dosages of cerebrolysin in patients with mild to moderate Alzheimer\u2019s disease. Alzheimer\u2019s Association 10th International Conference on Alzheimer\u2019s Disease and Related Disorders. Madrid, 15-20 July. Alzheimer\u2019s & Dementia, 2(Suppl.1):S364 (2006).<\/p>\n

\u00c1lvarez, A., Corzo, L., Couceiro, V., Sampedro, C., Cacabelos, R. Cerebrolysin reduces the increased levels of serum tumor necrosis factor-alpha in Alzheimer\u2019s disease. Alzheimer\u2019s Association 10th International Conference on Alzheimer\u2019s Disease and Related Disorders. Madrid, 15-20 July. Alzheimer\u2019s & Dementia, 2(Suppl.1): S370 (2006).<\/p>\n

Cacabelos, R. Introducci\u00f3n a la Medicina Gen\u00f3mica en Neurociencias. I Conferencia Anual EuroEspes, Coru\u00f1a, 15 Dic (2006).<\/p>\n

Cacabelos, R. Pharmacogenomics and therapeutic prospects in dementia. Pharmainnovation. Pharmaceutical Innovation. Bonn, 11-12 June (2007).<\/p>\n

\u00c1lvarez, X.A., Linares, C., Aleixandre, M., Cacabelos, R., Hitzl, M. Tratamiento neurotr\u00f3fico en la enfermedad de Alzheimer: Mecanismos moleculares y estudios cl\u00ednicos. XII Congreso Panamericano de Neurolog\u00eda. Santo Domingo, 7-11 Oct. pp. 16 (2007).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Garc\u00eda-Fantini, M., Linares, C., Aleixandre, M., Cacabelos, R., Hitzl, M. Interacci\u00f3n funcional entre TNF-alfa e IGF-I en la enfermedad de Alzheimer: Implicaciones patog\u00e9nicas y terap\u00e9uticas. XII Congreso Panamericano de Neurolog\u00eda. Santo Domingo, 7-11 Oct. pp. 51-52 (2007).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R., Moessler, H. Interaction between TNF-alpha and IGF-I in Alzheimer disease: Pathogenic and therapeutic implications. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1): 334 (2007).<\/p>\n

Cacabelos, R. Influence of pharmacogenetic factors on Alzheimer\u2019s disease. Therapeutics. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1): 4 (2007).<\/p>\n

Fern\u00e1ndez-Novoa, L., Llovo, R., Seoane, S., Bello, A., Rey, P., Corzo, L., Cacabelos, R. Cholesteryl ester transfer protein (CETP) gene and cholesterol metabolism in dementia. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1): 119 (2007).<\/p>\n

Isaza, C., Henao, J., Llovo, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Similar pharmacogenetic patterns of CYP2C19 in Spanish and Colombian populations. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1): 138 (2007).<\/p>\n

Isaza, C., Henao, J., Llovo, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. CYP2D6 in the Spanish population with dementia. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1): 138 (2007).<\/p>\n

Corzo, L., Fern\u00e1ndez-Novoa, L., Rodr\u00edguez, S., Cacabelos, R. Vascular risk factors and endothelial NOS3 polymorphism variants in Alzheimer\u2019s disease. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1):143-144 (2007).<\/p>\n

Lombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Lymphocyte subset markers and cytokine production in peripheral blood of patients with AD. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1):229 (2007).<\/p>\n

Cacabelos, R. La medicina gen\u00f3mica en las enfermedades degenerativas y el c\u00e1ncer. II Congreso Internacional sobre Tratamientos Complementarios y Alternativos en C\u00e1ncer. Madrid, 26 Mayo (2007).<\/p>\n

Cacabelos, R. Pharmacogenetics and therapeutic optimization in dementia. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):8-9 (2007).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Cacabelos, R., Moessler, H. Functional interaction of serum tumor necrosis factor-alpha and insulin growth factor-I in Alzheimer\u2019s disease. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):300 (2007).<\/p>\n

Lombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. IL-1beta, IL-6 and TNF-alpha inflammatory cytokines and lymphocyte subset markers in patients with Alzheimer\u2019s disease (AD). Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):302-303 (2007).<\/p>\n

Lombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Inflammatory and immune responses in patients with Alzheimer\u2019s disease (AD). Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):303 (2007).<\/p>\n

Lombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Llovo, R., Seoane, S., Corzo, L., Cacabelos, R. Cholesteryl ester transfer protein (CETP) gene and cholesterol in Alzheimer\u2019s disease. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):303-304 (2007).<\/p>\n

Lombardi, V.R.M., Llovo, R., Fern\u00e1ndez-Novoa, L., Seoane, S., Henao, J., Cacabelos, R. CYP2D6 in the Spanish population with dementia. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):304 (2007).<\/p>\n

Lombardi, V.R.M., Llovo, R., Fern\u00e1ndez-Novoa, L., Seoane, S., Henao, J., Cacabelos, R. Similar pharmacogenetic patterns of CYP2C19 in Spanish and Colombian populations. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):304-305 (2007).<\/p>\n

Lombardi, V.R.M., Llovo, R., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Genetic polymorphisms of cytochromes P450: CYP2D6, CYP2C19 and CYP2C9 in Spanish population. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):305 (2007).<\/p>\n

Corzo, L., Rodr\u00edguez, S., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Alzheimer\u2019s disease-associated peripheral markers are interrelated to lipid metabolism. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):307 (2007).<\/p>\n

Corzo, L., Rodr\u00edguez, S., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Endothelial NOS3 polymorphism influence on peripheral vascular markers in Alzheimer\u2019s disease. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):307-308 (2007).<\/p>\n

Tellado, I., Fraile, C., Cacabelos, R. Brain optical topography in Alzheimer\u2019s disease and vascular dementia. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):308 (2007).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Cruceiro, V., Cacabelos, R., Aleixandre, M., Moessler, H. Neuropsychiatric symptoms and ApoE-4 in patients with cognitive deterioration: Impact on functioning. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):335-336 (2007).<\/p>\n

Tellado, I., Fraile, C., Cacabelos, R. Impact of ApoE genotype on brain function as assessed by optical topography. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):363 (2007).<\/p>\n

Tellado, I., Fraile, C., Cacabelos, R. ACE genotype-related changes in brain optical topography. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):363-364 (2007).<\/p>\n

Corzo, L., Vallejo, A.I., Antelo, A.M., Lombardi, V., Cacabelos, R. E-JUR-94013; a nutraceutical compound with immunomodulatory effects in the elderly. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):416 (2007).<\/p>\n

Tellado, I., Fraile, C., Cacabelos, R. Brain optical topography patterns in stroke, vascular encephalopathy and migraine. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):426 (2007).<\/p>\n

Lombardi, V.R.M., Etcheverr\u00eda, J., D\u00edaz, J., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):Add. 5 (2007).<\/p>\n

Cacabelos, R. Dementia in Europe: Present and future challenges. Aiming for the Communities Living Together with Dementia \u2013 In Japan and the World. Aging and Dementia \u2013 the States in Japan and Abroad. Osaka International Convention Center, Osaka, 14 Oct. (2007).<\/p>\n

\u00c1lvarez X.A., Sampedro, C., Corzo, L., Cacabelos, R. Alterations of serum TNF-alpha and IGF-I levels in vascular dementia. Fifth International Congress on Vascular Dementia. Budapest, Hungary, Nov 8-11 (2007).<\/p>\n

Cacabelos, R. Medicina Gen\u00f3mica. Congreso Internacional de Medicina Biol\u00f3gica. Medicina Funcional de Vanguardia. Universidad Aut\u00f3noma de Guadalajara, Guadalajara, M\u00e9xico; 30 Nov., 2007. <\/p>\n

Cacabelos, R. Farmacogen\u00f3mica aplicada a las neurociencias cl\u00ednicas. II Conferencia Anual EuroEspes, Coru\u00f1a, Dic. 15 (2007).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Couceiro, V., Cacabelos, R., Doppler, E., Hitzl, M., Moessler, H. Cerebrolysin in moderate to moderately severe Alzheimer disease: Efficacy and safety analysis in a subgroup of a double-blind, placebo-controlled trial. Alzheimer\u2019s Association International Conference on Alzheimer\u2019s Disease (ICAD). Chicago, July 26-31 (2008).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Cacabelos, R., Linares, C., Granizo, E., Aleixandre, M., Moessler, H. Cerebrolysin reduces TNF-alpha and soluble TNF receptor-1 levels in the serum of Alzheimer disease patients. Alzheimer\u2019s Association International Conference on Alzheimer\u2019s Disease (ICAD). Chicago, July 26-31 (2008).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Cacabelos, R., Linares, C., Granizo, E., Aleixandre, M., Garc\u00eda-Fantini, M. Hyperactivity of peripheral TNF-alpha system in Alzheimer\u2019s disease: Interaction with serum IGF-1. Alzheimer\u2019s Association International Conference on Alzheimer\u2019s Disease (ICAD). Chicago, July 26-31 (2008).<\/p>\n

Cacabelos, R. Manejo pr\u00e1ctico de la farmacogen\u00e9tica en ni\u00f1os y adultos. Jornadas M\u00e9dicas, Hospital Espa\u00f1ol, M\u00e9xico DF, Febrero 16 (2008).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Cacabelos, R., Linares, C., Granizo, E., Aleixandre, M., Garc\u00eda-Fantini, M. Hyperactivity of peripheral TNF-alpha system in Alzheimer\u2019s disease: Interaction with serum IGF-I. Alzheimer\u2019s Association International Conference on Alzheimer\u2019s Disease. July 26-31. Alzheimer\u2019s & Dementia, 4(Suppl.2):T137 (2008).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Cruceiro, V., Cacabelos, R., Aleixandre, M., Doppler, E., Moessler, H. Cerebrolysin in moderate to moderately severe Alzheimer\u2019s disease: a subgroup analysis of efficacy and safety data. 12th Congress of the European Federation of Neurological Societies, Madrid, August 23-26. Eur. J. Neurol., 15(Suppl.3):24 (2008).<\/p>\n

Cacabelos, R. Pharmacogenomics in CNS Disorders. 51st Annual Meeting of the Japanese Society of Neurochemistry, Sept. 11. Bull. Jap Soc Neurochem., 47: 210 (2008).<\/p>\n

Cacabelos, R. Genotype-related phenotypic expression of biomarkers in dementia: Implications for pharmacogenomics. World Federation of Societies of Biological Psychiatry. 2nd WFSBP Asia-Pacific Congress and 30th Annual Meeting of JSBP. 11-13 Sept. The World Journal of Biological Psychiatry, Vol. 9(Suppl.1):82 (2008).<\/p>\n

Cacabelos, R. Farmacogen\u00f3mica en las enfermedades neurol\u00f3gicas. XXXII Reuni\u00f3n Anual Academia Mexicana de Neurolog\u00eda. Puerto Vallarta, 25 Oct. \u2013 1 Nov. (2008).<\/p>\n

Cacabelos, R. Genomic medicine and pharmacogenomics of neuropsychiatric disorders. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:26-29 (2008). <\/p>\n

Harguindey S, D\u00edaz de Otazu, R., Arlueca, J., Catal\u00e1n, J., Arranz, J.L., Orive, G., Reshkin, S.J., Cacabelos, R. Human neurodegenerative diseases (hndds) and cancer: an integral approach to the etiopathogenesis and treatment of hndds within the frame of the trophic factor withdrawal syndrome (TFWS). III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:66 (2008).<\/p>\n

Mart\u00ednez, E., Chac\u00f3n, R., Etcheverr\u00eda, I., Cacabelos, R., Lombardi, V.R.M. Cytotoxicity effects induced by FR-91 on human tumor cell lines. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:68 (2008).<\/p>\n

Mart\u00ednez, E., Chacon, R., Cacabelos, R., Etcheverr\u00eda, I., Lombardi, V.R.M. Effects of FR-91 on immune cells from healthy individuals and patients with non-Hodgkin lymphoma. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:68 (2008).<\/p>\n

Lombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Caspase 3 activity in PBMCs from Alzheimer\u2019s disease patients: when and why do cells die? III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:69 (2008).<\/p>\n

Des, J., P\u00e9rez, R., Alcaraz, M., Nebril, L., Fern\u00e1ndez-Novoa, L., Cacabelos, R. ACE-related blood pressure values in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:69-70 (2008).<\/p>\n

Des, J., P\u00e9rez, R., Alcaraz, M., Nebril, L., Fern\u00e1ndez-Novoa, L., Cacabelos, R. ACE-related brain hemodynamic parameters in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:70 (2008).<\/p>\n

P\u00e9rez, R., Des, J., Fraile, C., Fern\u00e1ndez-Novoa, L., Corzo, L., Cacabelos, R. FOS-related blood biochemical parameters and brain hemodynamics in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:70 (2008).<\/p>\n

P\u00e9rez, R., Des, J., Fraile, C., Fern\u00e1ndez-Novoa, L., Corzo, L., Cacabelos, R. APOE-related blood biochemical parameters and brain hemodynamics in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:71 (2008).<\/p>\n

Aguilar Aldrete, M.E., Moran Moguel, M.C., Sandoval-Ram\u00edrez, L., Rosales-G\u00f3mez, R.C., Guti\u00e9rrez-Rubio, S.A., Rodr\u00edguez-Vega, M.C., Parra Bernal, M.C., Cacabelos, R. Comparative study of APOE polymorphisms in the Mexican population: Alzheimer\u2019s disease vs. Indians and mestizos. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:74 (2008).<\/p>\n

\u00c1lvarez, A., Cacabelos, R., Mandler, M., Mattner, F. Mimovax: A novel approach for a safe vaccine for Alzheimer\u2019s disease. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:75 (2008).<\/p>\n

Fraile, C., Mart\u00ednez, R., Cacabelos-P\u00e9rez, N., Corzo, L., Fern\u00e1ndez-Novoa, L., Cacabelos-P\u00e9rez, R., Cacabelos, R. Presenilin-related biochemical and brain hemodynamic parameters in patients with Alzheimer\u2019s disease. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:75-76 (2008).<\/p>\n

Fraile, C., Llovo, R., Mart\u00ednez, R., Cacabelos-P\u00e9rez, N., Corzo, L., Fern\u00e1ndez-Novoa, L., Cacabelos-P\u00e9rez, R., Cacabelos, R. CYP2D6-related biochemical and brain hemodynamic parameters in patients with Alzheimer\u2019s disease. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:76 (2008).<\/p>\n

Mart\u00ednez, R., Cacabelos-P\u00e9rez, N., Cacabelos-P\u00e9rez, R., Cacabelos, R. CYP genes and drug metabolism: major substrates for antidepressants, neuroleptics and benzodiazepines. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:76-77 (2008).<\/p>\n

Llovo, R., Tudoli, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Genetic polymorphisms of Cytochrome P450: CYP2D6, CYP2C19, CYP2C9 and CYP3A5 in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:77 (2008).<\/p>\n

Llovo, R., Fern\u00e1ndez-Novoa, L., Seoane, S., Tudoli, I., Cacabelos, R. Pharmacogenetic patterns of CYP2C9 and VKORC1 in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:78 (2008).<\/p>\n

Corzo, L., Rodr\u00edguez, S., Cacabelos, R. Important role of novel vascular risk factors to decrease vascular risk in patients with dementia. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:78-79 (2008).<\/p>\n

Carril, J.C., Tudoli, I., Cacabelos, R. IL-6 and IL-6R gene polymorphisms and risk of stroke and neurodegeneration. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:79 (2008).<\/p>\n

Carril, J.C., Llovo, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Logistic regression as a useful tool to explain genetic risk of stroke. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:79 (2008).<\/p>\n

Fern\u00e1ndez-Novoa, L., Seoane, S., Llovo, R., Tudoli, I., Cacabelos, R. Vascular genetic risk factors in Alzheimer\u2019s disease. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:80 (2008).<\/p>\n

Tellado, I. Cacabelos, R. Effect of ACE genotype on brain bioelectrical activity. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:80 (2008).<\/p>\n

Fern\u00e1ndez-Novoa, L., Seoane, S., Llovo, R., Tudoli, I., Corzo, L., Cacabelos, R. Polygenic risk factors related to neurodegeneration in Alzheimer\u2019s disease: calculation of a genetic predisposition store (GPS). III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:90-81 (2008).<\/p>\n

Lombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Chronic activation of PBMCS in Alzheimer\u2019s disease patients. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:81 (2008).<\/p>\n

Corzo, L., Rodr\u00edguez, S., Fern\u00e1ndez-Novoa, L., Laredo, M., Cruceiro, V., Cacabelos, R. Association of novel vascular risk factors and cognitive function in dementia. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:82 (2008).<\/p>\n

Tellado, I., Cacabelos, R. Impact of APOE genotype on brain bioelectrical activity. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:82-83 (2008). <\/p>\n

Tellado, I., Fraile, C., Cacabelos, R. Influence of APOE genotype on brain function as assessed by Optical Topography. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:83 (2008).<\/p>\n

Laredo, M., Couceiro, V., \u00c1lvarez, A., Sampedro, C., Cacabelos, R. Neuropsychiatric symptoms and APOE-4 in cognitively impaired patients. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:84 (2008).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Corzo, L., Cacabelos, R. Immuno-trophic regulation in Alzheimer\u2019s disease: TNF-ALPHA\/IGF-I interactions. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:84 (2008).<\/p>\n

Mart\u00ednez, R., Alejo, R., Lombardi, V., Fern\u00e1ndez-Novoa, L., Corzo, L., Alcaraz, M., Nebril, L., Casas, A., Fraile, C., Vallejo, A., Cacabelos, R. Nutraceutical properties of E-SAR-94010 (LipoEsar\u00ae): APOE-related nutrigenomic profile. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:85 (2008).<\/p>\n

Mart\u00ednez, R., Fraile, C., Cacabelos-P\u00e9rez, N., Cacabelos-P\u00e9rez, R., Fern\u00e1ndez-Novoa, L., Corzo, L., Lombardi, V., Tellado, I., P\u00e9rez, R., Laredo, M., Cruceiro, V., \u00c1lvarez, A., Des, J., Cacabelos, R. APOE-related phenotypic profile in Alzheimer\u2019s disease and vascular dementia. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:85-89 (2008).<\/p>\n

Llovo, R., Fern\u00e1ndez-Novoa, L., Tudoli, I., Vallejo, A., Cacabelos, R. Genetic polymorphisms of several genes associated with key metabolic pathways in obesity. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:89-90 (2008).<\/p>\n

\u00c1lvarez, A., Cacabelos, R., Aleixandre, M., Linares, C., Granizo, E., Doppler, E., Moessler, H. Double-blind clinical trial with cerebrolysin, donepezil and a combination therapy in mild to moderate Alzheimer\u2019s disease. Second Joint Congress of GCNN and SSNN. Vienna, 1-3 March (2009). <\/p>\n

Cacabelos, R. Pharmacogenomic protocols in CNS disorders and dementia. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 18 (2009).<\/p>\n

Corzo, L., Rodr\u00edguez, S., Fern\u00e1ndez-Novoa, L., Laredo, M., Cruceiro, V., Cacabelos, R. Influence of vascular risk factors on cognitive status. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 105 (2009).<\/p>\n

Fern\u00e1ndez-Novoa, L., Seoane, S., Llovo, R., Tudoli, I., Corzo, L., Cacabelos, R. Polygenic risk factors in Alzheimer disease: Calculation of a genetic predisposition store (GPS). 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 147 (2009).<\/p>\n

Carril, J.C., Fern\u00e1ndez-Novoa, L., Llovo, R., Cacabelos, R. Logistic regression as a useful tool to explain genetic risk of stroke. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 154 (2009).<\/p>\n

Fern\u00e1ndez-Novoa, L., Llovo Mari\u00f1o, R., Tudoli, S., Seoane, S., Cacabelos, R. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 155 (2009).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Corzo, L., Cacabelos, R., Aleixandre, M., Vargas, M., Linares, C., Granizo, E. Modulatory effects of cerebrolysin on TNF-alpha and IGF.I in Alzheimer\u2019s disease. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 200 (2009).<\/p>\n

Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Cacabelos, R., Lombardi, V. Immune studies in peripheral blood of patients with Alzheimer\u2019s disease. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 206 (2009).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Cacabelos, R. Inflammatory biomarkers are associated with low IGF-I levels and disability in Alzheimer\u2019s disease. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 208 (2009).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Cruceiro, V., Cacabelos, R., Aleixandre, M., Vargas, M., Linares, C., Granizo, E., Doppler, E., Novak, P., Moessler, H. Cerebrolysin, donepezil and a combination therapy in Alzheimer\u2019s disease: Results of a double-blind clinical trial. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 231 (2009).<\/p>\n

Cacabelos, R. C\u00e1ncer y enfermedades neurodegenerativas (Ende) como opuestos metab\u00f3licos \u00e1cido-b\u00e1sicos. Enfoque gen\u00e9tico y factores de crecimiento en etiopatogenia y tratamiento. International Symposium. Transporte de protones y su inhibici\u00f3n (ITP) en la etiopatogenia, diagn\u00f3stico y tratamiento del c\u00e1ncer. Fundaci\u00f3n Ram\u00f3n Areces, Madrid, 28-29 Abril (2009). <\/p>\n

Takeda, M., Shibata, N., Kim, D.K., Cacabelos, R. Pharmacogenomics and nutrigenomics in CNS disorders of the elderly. IPA 2009 International Meeting. Brain Aging and Quality of Life, Rio de Janeiro, Brazil, 4-7 May, (2009).<\/p>\n

Cacabelos, R. Genomic mechanisms of neurodegeneration: implications for pharmacogenomics and nutrigenomics. The Second Annual Iberian Congress on Anti-Aging Medicine and Biomedical Technologies. Vilamoura-Algarve, Portugal, June 4-6, (2009).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Cacabelos, R., Novak, P., Moessler, H. Opposite effects of cerebrolysin on serum TNF-alpha and IGF-I levels in Alzheimer\u2019s disease. Alzheimer\u2019s Association 2009 International Conference on Alzheimer\u2019s Disease (ICAD). Vienna, 11-16 July (2009).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Cacabelos, R. Overexpression of inflammation markers in Alzheimer\u2019s disease: Clinical correlates. Alzheimer\u2019s Association 2009 International Conference on Alzheimer\u2019s Disease (ICAD). Vienna, 11-16 July (2009).<\/p>\n

Cacabelos, R. Biomarkers and pharmacogenomics. Alzheimer\u2019s Association 2009 International Conference on Alzheimer\u2019s Disease (ICAD). Vienna, 11-16 July (2009).<\/p>\n

Cacabelos, R. Conferencia Inaugural. III Congreso Internacional sobre Tratamientos Complementarios y Alternativos en C\u00e1ncer. World Association for Cancer Research, Madrid, 31 Oct-1 Nov. (2009).<\/p>\n

\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Clinical relevance of peripheral inflammatory biomarkers in Alzheimer\u2019s disease and vascular dementia. Sixth International Congress on Vascular Dementia, Barcelona, 19-22 Nov. (2009).<\/p>\n

Cacabelos, R. Medicina personalizada en el abordaje cl\u00ednico de la demencia: Farmacogen\u00f3mica de la enfermedad de Alzheimer. IV Conferencia Anual EuroEspes. Avances en Medicina Gen\u00f3mica, Coru\u00f1a, Dic. 19 (2009). <\/p>\n

Cacabelos, R. Nutrigenomic component of marine biotechnology products for human Health. 239th American Chemical Society National Meeting & Exposition. San Francisco, USA, March 21-25, pp. TECH-58 (2010).<\/p>\n

Cacabelos, R. Farmacogen\u00e9tica de la enfermedad de Alzheimer. XXXIII Congreso Nacional de Farmacolog\u00eda para Estudiantes. Universidad Aut\u00f3noma de Madrid, Madrid, 4-5 Mayo, 2010.<\/p>\n

Cacabelos, R., Avramopoulos, Baskys, A., Cai, Y. Genetic testing in neuropsychiatry: APOE and beyond. 10th Annual Meeting of the International College of Geriatric Psychoneuropharmacology. The Divani Palace Acropolis Hotel, Athens, 15-18 September, 2010.<\/p>\n

Cacabelos, R. Genomics and pharmacogenomics of psychotic disorders. VII Congress of the Polish Society of Psychogeriatrics. Wroclaw, 2-3 December, 2010.<\/p>\n

\u00c1lvarez, A., Cacabelos, R., Couceiro, V., Aleixandre, M., Doppler, E., Novak, P., Moessler, H. Effects of Cerebrolysin on neuropsychiatric symptoms in Alzheimer\u2019s disease: results of a randomized, placebo-controlled trial. 14th Congress of the European Federation of Neurological Societies. Eur. J. Neurol., 17(Suppl. 3), 72 (2010).<\/p>\n

\u00c1lvarez, A., Sampedro, C., Couceiro, V., Cacabelos, R., Garc\u00eda-Fantini, M., Aleixandre, M., Linares, C., Granizo, E. Apathy influences functional impairment in mild to moderate Alzheimer\u2019s disease. 14th Congress of the European Federation of Neurological Societies. Eur. J. Neurol., 17(Suppl. 3), 86 (2010).<\/p>\n

Cacabelos, R. Nutrigen\u00f3mica y farmacogen\u00f3mica: de la teor\u00eda a la pr\u00e1ctica. VII Congreso Internacional de Nutrici\u00f3n, Alimentaci\u00f3n y Diet\u00e9tica. XV Jornadas Nacionales de Nutrici\u00f3n Pr\u00e1ctica. Sociedad Espa\u00f1ola de Diet\u00e9tica y Ciencias de la Alimentaci\u00f3n. Universidad Complutense, Madrid, 30-31 Marzo- 1 Abril, 2011. Revista de Nutrici\u00f3n Pr\u00e1ctica 15:9-10 (2011).<\/p>\n

Cacabelos, R. Functional genomics and pharmacogenomics of CNS disorders. 10th World Congress of Biological Psychiatry, pp. 100, Prague, 29 May \u2013 2 June, 2011.<\/p>\n

Fern\u00e1ndez-Novoa, L., Cacabelos, R. APOE and CYP2D6 in CNS disorders. European Human Genetics Conference 2011, Amsterdam, 28-31 May, 2011. Eur J Hum Genet 19 (Suppl. 2):284 (2011).<\/p>\n

Fern\u00e1ndez-Novoa, L., Carril, J., Seoane, S., Cacabelos, R. Characterization of the genomic risk profile in cerebrovascular diseases. European Human Genetics Conference 2011, Amsterdam, 28-31 May, 2011. Eur J Hum Genet 19 (Suppl. 2):290 (2011).<\/p>\n

Fern\u00e1ndez-Novoa, L., Seoane, S., Carril, J., Garc\u00eda-Ag\u00fandez, J.A., Cacabelos, R. LRRK2 mutations in sporadic and familial Parkinson disease. European Human Genetics Conference 2011, Amsterdam, 28-31 May, 2011. Eur J Hum Genet 19 (Suppl. 2):300 (2011).<\/p>\n

Cacabelos, R. Pharmacogenomics of schizophrenia and lipid metabolism alterations in CNS disorders. 3rd World Congress of Asian Psychiatry 2011. Melbourne, 31 July \u2013 4 August, 2011. Asian Journal of Psychiatry 4(Suppl. 1): 11 (2011).<\/p>\n

Cacabelos, R., S\u00e1nchez, J. Introduction to the World Guide of Pharmacogenomics. VI Conferencia Annual EuroEspes, Gen-T 8:34-35 (2011).<\/p>\n

Carril, J.C., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Caracterizaci\u00f3n del perfil gen\u00e9tico de riesgo cerebrovascular. VI Conferencia Annual EuroEspes, Gen-T 8:88 (2011).<\/p>\n

Carril, J.C., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Citoquinas proinflamatorias polim\u00f3rficas como marcadores gen\u00e9ticos de aterosclerosis. VI Conferencia Annual EuroEspes, Gen-T 8:88-89 (2011).<\/p>\n

Canuet, L., Tellado, I., Couceiro, V., Fraile, C., Cacabelos, R. Perfil fenot\u00edpico EEG de conectividad funcional y actividad oscilatoria en la enfermedad de Alzheimer. VI Conferencia Annual EuroEspes, Gen-T 8:89-90 (2011).<\/p>\n

Canuet, L., Tellado, I., Corzo, L., Fraile, C., Cacabelos, R. Relaci\u00f3n del genotipo APOE y niveles s\u00e9ricos de LDL-colesterol con la actividad bioel\u00e9ctrica cerebral en pacientes con enfermedad de Alzheimer. VI Conferencia Annual EuroEspes, Gen-T 8:90 (2011).<\/p>\n

Corzo, L., Lombardi, V., Alejo, R., Rodr\u00edguez, S., Cacabelos, R. Bioproperties and clinical effects of Juritrofin (DefenVid\u00ae). VI Conferencia Annual EuroEspes, Gen-T 8:91-92 (2011).<\/p>\n

Corzo, L., Rodr\u00edguez, S., Alejo, R., Cacabelos, R. Biological properties of Mineraxin. VI Conferencia Annual EuroEspes, Gen-T 8:92 (2011).<\/p>\n

Fern\u00e1ndez-Novoa, L., Corzo, L., Seoane, S., Carril, J.C., Cacabelos, R. A genomic approach to histamine function. VI Conferencia Annual EuroEspes, Gen-T 8:93-94 (2011).<\/p>\n

Fern\u00e1ndez-Novoa, L., Cacabelos, R. Histamine function in brain disorders. VI Conferencia Annual EuroEspes, Gen-T 8:94 (2011).<\/p>\n

Lombardi, V.R.M., Carrera, I., Etcheverr\u00eda, I., Mart\u00ednez, E., Chac\u00f3n, R., Cacabelos, R. Prevenci\u00f3n de colitis experimental cr\u00f3nica inducida por dextr\u00e1n sulfato s\u00f3dico (DSS) en ratones tratados con FR-91. VI Conferencia Annual EuroEspes, Gen-T 8:94-95 (2011).<\/p>\n

Lombardi, V.R.M., Alejo, R., Etcheverr\u00eda, I., Pablos, A., Cacabelos, R. Testaje experimental de las propiedades de bioproductos en preparados de Alimentos Naturales, S.A. VI Conferencia Annual EuroEspes, Gen-T 8:95 (2011).<\/p>\n

Tellado, I., Canuet, L., Couceiro, V., Fraile, C., Cacabelos, R. Cambios en la actividad bioel\u00e9ctrica cerebral durante el envejecimiento y el deterioro cognitivo. VI Conferencia Annual EuroEspes, Gen-T 8:95-96 (2011).<\/p>\n

Tellado, I., Canuet, L., Fraile, C., Cacabelos, R. Influencia del alelo APOE-4 sobre la funci\u00f3n cerebral en ancianos sanos. VI Conferencia Annual EuroEspes, Gen-T 8:96 (2011).<\/p>\n

Cacabelos, R. \u00bfSe puede prevenir la enfermedad de Alzheimer? IX Jornadas de Actualizaci\u00f3n en Vacunas. Vacunas para una salud global. Sal\u00f3n de Actos Casa de las Mariposas, Almer\u00eda, 1-2 Octubre (2012).<\/p>\n

Cacabelos, R. Farmacogen\u00f3mica y vacuna anti-Alzheimer. XXXI Lecci\u00f3n Memorial. Visi\u00f3n cr\u00edtica de la prevenci\u00f3n cardiovascular: focaliz\u00e1ndose en los factores determinantes del envejecimiento saludable. Fundaci\u00f3n Fern\u00e1ndez-Cruz. Auditorio del Hospital Cl\u00ednico San Carlos, Madrid, 26 Nov (2012).<\/p>\n

Cacabelos, R. Genomics and Pharmacogenomics of neurodegeneration. Longeva. Congresso Internazionale ECM. Medicina preventiva, predittiva e rigenerativa. Fiera Milano Rho, Mil\u00e1n, 30 Nov- 1 Dic (2012).<\/p>\n

Aliev, G., Bragin, V., Cacabelos, R. Implication of integrative treatment for real-life geriatric patients with depression, dementia and multiple chronic diseases: A 60-month follow-up of a naturistic study. 5th Clinical Trial son Alzheimer\u2019s disease (CTAD) Conference. Montecarlo, France, Oct 29-31 (2012). J Nutrition Health Ageing 16:840-841 (2012).<\/p>\n

Corzo, L., Rodr\u00edguez, S., Cacabelos. Novel vascular risk factor evaluation can improve the prediction and prevention of vascular risk in dementia. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-07-009 (2013).<\/p>\n

Corzo, L., Rodr\u00edguez, S., Fern\u00e1ndez-Novoa, L., Couceiro, V., Cacabelos, R. Vascular risk factors in dementia: Influence of APOE, MTHFR, NOS3, PSEN1 and ACE polymorphisms and association with cognitive function scores. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-07-015 (2013).<\/p>\n

Cacabelos, R. Influence of pleiotropic genes in CNS Pharmacogenomics. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, S-048-004 (2013).<\/p>\n

Fern\u00e1ndez-Novoa, L., Seoane, S., Carril, J.C., Ag\u00fandez, J.A., Cacabelos, R. G2019S mutation in sporadic and familial Parkinson\u2019s disease. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-10-004 (2013).<\/p>\n

Fern\u00e1ndez-Novoa, L., Lombardi, V., Etcheverr\u00eda, I., Cacabelos, R. The effects of acute and chronic psychological stress on immune function in a rat model. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-12-016 (2013).<\/p>\n

Carril, J.C., Corzo, L., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Characterization of the genomic risk profile in cerebrovascular diseases. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-13-022 (2013).<\/p>\n

Carril, J.C., Torrellas, C., Fraile, C., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Error rate in antidepressant Drug prescription: the importance of personalized medicine. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-18-005 (2013).<\/p>\n

Carril, J.C., Torrellas, C., Fraile, C., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Pharmacogenetics as a predictive tool to reduce errors in the administration of anxiolytics, hypnotics and sedatives. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-18-006 (2013).<\/p>\n

Carril, J.C., Fraile, C., Torrellas, C., Couceiro, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R. The importance of pharmacogenetics in the treatment of psychotic disorders. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-18-009 (2013).<\/p>\n

Carril, J.C., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Characterization of CYP3A polymorphisms in the Spanish population. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-18-015 (2013).<\/p>\n

Tellado, I., Corzo, L., Canuet, L., Couceiro, V., Fraile, C., Cacabelos, R. Age-related changes in brain networks: A bioelectrical source localization and functional connectivity study in resting state. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-20-003 (2013).<\/p>\n

Canuet, L., Tellado, I., Couceiro, V., Fraile, C., Fern\u00e1ndez-Novoa, L., Ishii, R., Takeda, M., Cacabelos, R. Phenotypic profile of brain functional connectivity and oscillatory activity in Alzheimer\u2019s disease. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-21-010 (2013).<\/p>\n

Canuet, L., Tellado, I., Corzo, L., Fern\u00e1ndez-Novoa, L., Fraile, C., Torrellas, C., Ishii, R., Takeda, M., Cacabelos, R. Association of APOE genotype and LDL-cholesterol levels with brain electrical activity in Alzheimer\u2019s disease. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-21-011 (2013).<\/p>\n

Canuet, L., Ishii, R., Pascual-Marqui,M., Iwase, M., Takeda, M., Cacabelos, R., del Pozo, F., Maestu, F. Resting-state EEG source localization and functional connectivity in schizophrenia-like psychosis of epilepsy and Alzheimer\u2019s disease using eLORETA. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-84-002 (2013).<\/p>\n

Cacabelos, R. Pharmacogenomics of lipid metabolism dysfunction in dementia. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, S-100-004 (2013).<\/p>\n

Fern\u00e1ndez-Novoa, L., Tellado, I., Canuet, L., Couceiro, V., Fraile, C., Cacabelos, R. Impact of APOE-4 allele on brain activity in aging. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-26-004 (2013).<\/p>\n

Fern\u00e1ndez-Novoa, L., Carril, J.C., Seoane, S., Cacabelos, R. An association study between histamine and polymorphisms in immune system genes in mental disorders. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-28-025 (2013).<\/p>\n

Cacabelos, R. APOE-TOMM40 and CYP2D6 in the Pharmacogenomics of dementia. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.<\/p>\n

Carril, J.C., Cacabelos, R. Characterization of CYP3A polymorphisms in the Spanish population. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.<\/p>\n

Carril, J.C., Corzo, L., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos. Characterization of the genomic risk profile in cerebrovascular diseases. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.<\/p>\n

Torrellas, C., Fraile, C., Carril, J.C., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Error rate in antidepressant Drug prescription: the importance of personalized medicine. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.<\/p>\n

Torrellas, C., Pi\u00f1eiro, S., Villanueva, M.J., Solveira, C., Fraile, C., Carril, J.C., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Hypertension management: benefits of pharmacogenetics. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.<\/p>\n

Torrellas, C., Fraile, C., Carril, J.C., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Pharmacogenetics as a predictive tool to reduce errors in the administration of anxiolytics, hypnotics and sedatives. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.<\/p>\n

Carril, J.C., Fraile, C., Torrellas, C., Couceiro, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R. The importance of pharmacogenetics in the treatment of psychotic disorders. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.
\nL\u00f3pez-Mu\u00f1oz F, Salado-Font S, P\u00e9rez-Nieto MA, Cacabelos R. Evolution ofCamilo Jos\u00e9 Cela University\u2019s international publications in health sciences: Bibliometric analysis. XI Foro Internacional sobre Evaluaci\u00f3n de la Calidad de la Investigaci\u00f3n y la Educaci\u00f3n Superior (FECIES). Bilbao, 8-10 July (2014).<\/p>\n

Cacabelos R. Nutrigenomics and nutraceutical intervention as a preventive strategy in lipid metabolism and age-related disorders. AMEC DACH 2014. Aesthetic & Anti-Aging Medicine European Congress. Berlin 20-21 June, 2014.<\/p>\n

Cacabelos R, Goldgaber D, Vostrov A, Matsuki H, Torrellas C, Carril JC. TOMM40 poly T variants modify the pharmacogenetic response to conventional treatments in Alzheimer\u2019s Disease. 7th Santorini Conference Biologie Prospective. Systems Medicine, Personalized Health and Therapy. ESPT. Sept 25-27, 2014.<\/p>\n

Carril JC, Cacabelos R. Atherogenic biomarkers in vascular dementia: the role of inflammation in neurodegeneration. 7th Santorini Conference Biologie Prospective. Systems Medicine, Personalized Health and Therapy. ESPT. Sept 25-27, 2014.<\/p>\n

Corzo L, Carril JC, Rodr\u00edguez S, Couceiro V, Cacabelos R. Vascular risk factors in dementia: Influence of APOE, MTHFR, NOS3, PSEN1 and ACE polymorphysms and association with cognitive function scores. 7th Santorini Conference Biologie Prospective. Systems Medicine, Personalized Health and Therapy. ESPT. Sept 25-27, 2014.<\/p>\n

Corzo L, Rodr\u00edguez S, Carril JC, Cacabelos. Relationships between genetic vascular risk polymorphysms and serum vascular biomarkers. 7th Santorini Conference Biologie Prospective. Systems Medicine, Personalized Health and Therapy. ESPT. Sept 25-27, 2014.<\/p>\n

Torrellas C, Carril JC, Cacabelos R. Pharmacogenetics of antidepressant drugs: Optimizing prescription. 7th Santorini Conference Biologie Prospective. Systems Medicine, Personalized Health and Therapy. ESPT. Sept 25-27, 2014.<\/p>\n

Cacabelos R. Pharmacogenetics of psychotropic drugs: The UCJC pharmacogenetic card for personalized treatment. WPA Regional Congress, Osaka International Convention Center, Osaka, Japan, 4-6 June, 2015.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Congresos Takagi, T., Tanizawa, O., Sugita, N., Mori, M., Otsuki, Y., Yamaji, K., Kurachi, K., Cacabelos, R., Nishimura, T., Senba, E., Tohyama, M., Shiotani, Y. Study of immunoreactive- oxytocin in human placenta and its localization. Proc. 56th Jap. Cong. Endocrinol., Osaka, Folia Endocrinol. Jap. 59:652 (1983). Cacabelos, R. Effect of social and individual factors on […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"Takagi, T., Tanizawa, O., Sugita, N., Mori, M., Otsuki, Y., Yamaji, K., Kurachi, K., Cacabelos, R., Nishimura, T., Senba, E., Tohyama, M., Shiotani, Y. Study of immunoreactive- oxytocin in human placenta and its localization. Proc. 56th Jap. Cong. Endocrinol., Osaka, Folia Endocrinol. Jap. 59:652 (1983). \r\n\r\nCacabelos, R. Effect of social and individual factors on the inner organization and efficiency of a multidisciplinary group. 10th World Cong. Soc. Psychiatry, Osaka, Abst.129 (1983). \r\n\r\nCacabelos, R. Chronological changes in hypothalamic histamine and catecholamines after bilateral adrenalectomy. 5th Meet. Histamine Res., Okayama, 18 Nov. (1983). \r\n\r\nOtsuki, Y., Takagi, T., Mori, M., Sugita, N., Cacabelos, R., Yamaji, K., Tanizawa, O. Immunoreactive vasopressin in human placenta. Proc. 57th Jap. Cong. Endocrinol., Tokyo, Folia Endocrinol. Jap., 60:344 (1984), \r\n\r\nWada, H., Watanabe, T., Yamatodani, A., Itoi, N., Cacabelos, R., Seo, M., Kiyono, S., Nagai, K., Nakagawa, H. Physiological functions of histamine in the brain. Frontiers in histamine research. An International Symposium. Paris, Abst. 44 (1984). \r\n\r\nCacabelos, R., Yamatodani, A., Watanabe, T., Takagai, T., Tanizawa, O., Hariguchi, S., Nishimura, T., Wada, H. Neuroendocrine functions of histamine: Putative modulations on ACTH, vasopressin, and oxytocin. Frontiers in histamine research. An International Symposium. Paris, Abst. 49 (1984). \r\n\r\nYamatodani, A., Fukuda, H., Cacabelos, R., Watanabe, T., Wada, H. A sensitive and specific method for determination of histamine in the brain by high-performance liquid chromatography-fluorometry. Frontiers in histamine research. An International Symposium. Paris, Abst. 80 (1984). \r\n\r\nCacabelos, R., Takagi, T., Otsuki, Y., Sugita, N., Tanizawa, O., Nishimura, T. Sequential evolution of oxytocin and vasopressin in the hypothalamo-hypophyseal system after adrenalectomy. Proc. 57th Jap. Cong. Endocrinol., Kobe, Folia Endocrinol. Jap., 60:1132 (1984). \r\n\r\nWada, H., Watanabe, T., Yamatodani, A., Cacabelos, R., Itoi, N., Seo, M., Kiyono, S., Nagai, K., Nakagawa, H. Physiological function of the histaminergic system in the rat brain. Proc. 8th Ann. Meet. Jap. Soc. Neurosci., Osaka, A-1C23, pp. 64 (1984). \r\n\r\nCacabelos, R. Effects of religious education in a pseudocommunist community. Proc. 19th Kansai Cong. Jap. Assoc. Educ. Med., & 6th Jap. Speak. World Conf. Soc. Psychiatry, Osaka, pp. 14-15 (1984).\r\n\r\nCacabelos, R., Yamatodani, A., Wada, H., Hariguchi, S., Nishimura, T. Histamine within the hypothalamo-hypophyseal system after bilateral adrenalectomy in rats. Proc. 22th Cong. Jap. Neurochem. Soc., Osaka (1983), Neurochem. Res., 9: 1165 (1984). \r\n\r\nCacabelos, R., Yamatodani, A., Wada, H., Hariguchi, S., Tada, K., Takeda, M., Nishimura. T., Takagi, T., Sugita, N., Tanizawa, O. On the chronological changes in hypothalamic catecholamines and plasma ACTH after bilateral adrenalectomy. Proc. 22th Cong. Jap. Neurochem. Soc., Osaka (1983); Neurochem. Res., 9: 1165-1166 (1984). \r\n\r\nYamatodani, A., Cacabelos, R., Watanabe, T., Wada, H. Effect of alpha-fluoromethylhistidine on circadian rhythms and the neuroendocrine system. Proc. 58th Jap. Pharmacol. Soc. Gen. Asamb., Tokyo, pp. 249 (1985). \r\n\r\nNishimura, T., Cacabelos, R., Suzuki, H., Takagi, T., Hariguchi, S., Tanizawa, O. Age-related vasopressin and oxytocin changes in the CNS. Proc. XVIth Int. Cong. ISPNE, Kyoto, pp. 59 (1985). \r\n\r\nCacabelos, R., Yamatodani, A., Watanabe, T., Hariguchi, S., Nishimura, T., Wada, H. Histaminergic neuromodulation of the corticotropinergic system. Proc. XVIth Int. Cong. ISPNE, Kyoto, pp. 99 (1985). \r\n\r\nTakagi, T., Otsuki, Y., Sugita, N., Tanizawa, O., Cacabelos, R., Nishimura, T. Age- and sex-related vasopressin and oxytocin changes in the CNS. Proc. 58th Jap. Cong. Endocrinol., Sendai, Folia Endocrinol. Jap., 61:388 (1985). \r\n\r\nCacabelos, R. Biological verification of neurocybernetical hypothesis. 77th Neurosci. Meet., Osaka, Abst. l (1985). \r\n\r\nNiigawa, H., Cacabelos, R., Tanaka, S., Miyazawa, M., Suzuki, H., Takeda, M., Tada, K., Hariguchi, S., Nishimura, T. Changes in plasma and CSF amines and small peptides in dementia patients. Proc. 22th Cong. Geriat., Tokyo, Jpn. J. Geriat., 22:112 (1985). \r\n\r\nCacabelos, R., Yamatodani, A., Fukui, H., Watanabe, T., Nishimura, T., Wada, H. Age- and sex-related changes in histamine and H-1 receptors in the hypothalamo-hypophyseal system after endocrine manipulation. Proc. 2nd Cong. ENEA, Milan, J. Endocrinol. Invest., 8(Suppl. 3):25 (1985). \r\n\r\nNishimura, T., Niigawa, H., Cacabelos, R., Tada, K., Hariguchi, S. Changes in histamine and neuropeptides in plasma and CSF of dementia patients. Koseisho-shinkeishikan- kenkyu itakumi. Ronenki no chiho no byoin. Byotai chiryo ni kansuru kenkyu. Report 15, Tokyo (1985). \r\n\r\nWada, H., Watanabe, T., Yamatodani, A., Cacabelos, R., Itoi, N., Kiyono, S., Seo, M., Nagai, K., Kanagawa, H. The distribution of the histaminergic neuron system and its physiological function in rat brain. Neurosci. Res. Suppl. 1: S112 (1985). \r\n\r\nYamatodani, A., Cacabelos, R., Watanabe, T., Wada, H. Effects of alpha-fluoromethylhistidine (FMH) on circadian rhythm and neurosecretory system. Jap. J. Pharmacol., 39:87P (1985).\r\n\r\nNiigawa, H., Cacabelos, R., Hariguchi, S., Nishimura, T. Interactions of histamine and vasopressin in dementia. Proc. 6th Meet. Neuropsychiat., Osaka, Abst. 3 (1986). \r\n\r\nltowi, N., Yamatodani, A., Goto, M., Cacabelos, R., Wada, H. Effect of alpha-fluoromethylhistidine administration on the plasma corticosterone level in mice. Jap. J. Pharmacol., 40:155P (1986). \r\n\r\nCacabelos, R., Yamatodani, A., Watanabe, T., Takagi, T., Tanizawa, O., Hariguchi, S., Nishimura, T., Wada, H. Effects of alpha-fluoromethylhistidine on ACTH, vasopressin, and oxytocin in the hypothalamo-hypophyseal system and plasma. Neurochem. Res., 11:149 (1986).\r\n\r\nCacabelos, R., Yamatodani, A., Miyake, A., Niigawa, H., Tada, K., Hariguchi, S., Nishimura, T., Wada, H. 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(1989). \r\n\r\nRodr\u00edguez, A., Cacabelos, R., Mateos, R. Estudio de la enfermedad de Alzheimer: Estrategias epidemiol\u00f3gicas y neuroqu\u00edmicas. II Symp. Intern. Gerontol. Psicogeriat., Murcia, 22-25 Febr. (1989). \r\n\r\nCacabelos, R. Predictores biol\u00f3gicos en la enfermedad de Alzheimer. II Workshop sobre Marcadores Biol\u00f3gicos en Psiquiatr\u00eda. Societat Catalana de Psiquiatr\u00eda, Sitges, 31 Marzo (1989). \r\n\r\nCacabelos, R. Bioqu\u00edmica. P\u00e9ptidos del sue\u00f1o. Symposium El Sue\u00f1o y sus Alteraciones. Academia de Ciencias M\u00e9dicas, Barcelona. 3 Mayo (1989). \r\n\r\nCacabelos, R. Demencia senil. Marcadores diagn\u00f3sticos y alternativas terap\u00e9uticas. III Jornadas de Geriatr\u00eda. Colegio Oficial de M\u00e9dicos. Barcelona, Mayo 16-17 (1989). \r\n\r\nCacabelos, R., Fern\u00e1ndez, M., Otero, F., \u00c1lvarez, X.A., Albarr\u00e1n, M.A., P\u00e9rez, A., Borr\u00e1s, C., Rodr\u00edguez, A. Marcadores neuroqu\u00edmicos para diagn\u00f3stico diferencial entre depresi\u00f3n involutiva y demencia senil. V Symposium Nacional del Comit\u00e9 Espa\u00f1ol para la Prevenci\u00f3n y Tratamiento de las Depresiones (PTD). La Toja, Mayo 26-27 (1989). \r\n\r\nCacabelos, R. Bases neuroqu\u00edmicas de la depresi\u00f3n. I Jornadas Cient\u00edficas de la Sociedad Gallega de Psiquiatr\u00eda. Neuroqu\u00edmica de la Depresi\u00f3n. Santiago de Compostela, Mayo 29 (1989). \r\n\r\nFari\u00f1as, F., Albarr\u00e1n, M.A., Garc\u00eda Alonso, L., Lodeiro, C., Cacabelos, R. Respuesta de GH inducida por GRF(1-29)NH2 en ni\u00f1os con talla baja asociada a trastornos del sistema inmune y metabolopat\u00edas. An. Esp. Pediatr\u00eda 30 (Supl. 37):54 (1989). \r\n\r\nAlbarr\u00e1n, M.A., Fari\u00f1as, F., Lodeiro, C., Garc\u00eda Alonso, L., Cacabelos, R. Respuesta de Gh a GRF en ni\u00f1os con talla baja idiop\u00e1tica asociada a trastornos del sistema nervioso central. An. Esp. Pediatr\u00eda 30 (Supl. 37):43-44 (1989). \r\n\r\nFari\u00f1as, F., \u00c1lvarez, X.A., Albarr\u00e1n, M.A., Garc\u00eda Alonso, L., Lodeiro, C., Cacabelos, R. Test de estimulaci\u00f3n con GRF(1-29)NH2 en ni\u00f1os con talla baja familiar y talla baja asociada a trastornos metab\u00f3licos e inmunol\u00f3gicos. VIII Reuni\u00f3n Nacional del F.I.S.s.s., Santander, Junio 1-3, pp. 132 (1989). \r\n\r\nFern\u00e1ndez, M., \u00c1lvarez, X.A., Otero, F., Cornes, J.M., Lois, J.M., Borr\u00e1s, C., Rodr\u00edgues, A., Di\u00e9guez, C., Cacabelos, R. Test de GRF: Potencial marcador diagn\u00f3stico en patolog\u00eda neuropsiqui\u00e1trica. VIII Reuni\u00f3n Nacional del F.I.S.s.s., Santander, Junio 1-3, pp. 124 (1989). \r\n\r\n\u00c1lvarez, X.A., Couto, D.F., Aradas, Y., Casal, C., Bello, J.A., Cacabelos, R. Efectos del GRF(1-29)NH2 sobre la memoria a corto plazo (MCP). VIII Reuni\u00f3n Nacional del F.I.S.s.s., Santander, Junio 1-3, pp. 122 (1989). \r\n\r\nOtero, F., \u00c1lvarez, X.A., Fern\u00e1ndez, M., Ver\u00edsimo, J., Serrano, F., P\u00e9rez, T., Otero, T., Di\u00e9guez, C., Cacabelos, R. Respuesta de Gh a GRF en pacientes neum\u00f3patas y cardi\u00f3patas de edad avanzada. VIII Reuni\u00f3n Nacional del F.I.S.s.s., Santander, Junio 1-3, pp. 123 (1989).\r\n\r\nCacabelos, R. Neuroendocrinolog\u00eda de la E.A. Simposium Alzheimer. Reuni\u00f3n Grupo Demencias SEN. Marcadores Biol\u00f3gicos y Perspectivas Terap\u00e9uticas en la Enfermedad de Alzheimer. Palma de Mallorca, Junio 8 (1989). \r\n\r\nCacabelos, R. Neuroqu\u00edmica del sue\u00f1o. Workshop sobre Trastornos del Sue\u00f1o. Sanatorio Psiqui\u00e1trico de Conxo. Santiago de Compostela, Junio 16 (1989). \r\n\r\nCacabelos, R. Neuroendocrine markers in Alzheimer\u2019s disease: New prospects for diagnosis and treatment. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Supl. 2):24 (1989). \r\n\r\nFern\u00e1ndez, M., \u00c1lvarez, X.A., Otero, F., Couto, D.F., Pe\u00f1alva, A., Lorenzo, A., Borr\u00e1s, C.G., P\u00e9rez, A., Albarr\u00e1n, M.A., Rodr\u00edguez, A., Cacabelos, R. GRF-induced GH response in alcoholic patients. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2):77 (1989). \r\n\r\nAlbarr\u00e1n, M.A., P\u00e9rez, A., Rubia, F.J., Cacabelos, R. GRF-induced GH response in mental retardation and attention-deficit hyperactivity disorders. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2): I 73 (1989). \r\n\r\nP\u00e9rez, A., Niigawa, H., Nishimura, T., Cacabelos, R. Studies of neuropeptides and monoamines in body fluids of patients with senile dementia (SDAT) and multi-infarct dementia (MID). 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2):175 (1989). \r\n\r\n\u00c1lvarez, X.A., Otero, F., Ver\u00edsimo, 3., Serrano, F., P\u00e9rez, T., Otero, T., Fern\u00e1ndez, M., Couto, D.F., Pe\u00f1alva, A., Cacabelos, R. GRF-induced GH response in lung and heart disease in the elderly. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2):177 (1989). \r\n\r\nCouto, D.F., \u00c1lvarez, X.A., Franco, A., Casas, X., Cerqueiro, J.M., de la Campa, A., Cacabelos, R. Effects of GRF(1-29)NH2 on cognitive functions: Neuropsychological and neuroendocrine assessment. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2):76 (1989). \r\n\r\nOtero, F., Fern\u00e1ndez, M., \u00c1lvarez, X.A., Albarr\u00e1n, M., P\u00e9rez, A., Couto, D.F., Borr\u00e1s, C.G., Cornes, M., Mallo, F., Rodr\u00edguez, A., Cacabelos, R. GRF-induced GH response in schizophrenia, depressive disorders and senile dementia of the Alzheimer type. 4th Meeting ENEA, Santiago de Compostela, June 28-30. J. Endocrinol. Invest., 12 (Suppl. 2):178 (1989). \r\n\r\nFari\u00f1as, F., Albarr\u00e1n, M.A., Garc\u00eda Alonso, L., Lodeiro, C., Cacabelos, R. GRF-induced GH response in children with familiar short statures and idiopathic short stature associated with immunological and\/or metabolic disease. International Symposium on Growth and Reproduction, Lugo, June 27, pp. 31 (1989). \r\n\r\nAlbarr\u00e1n, M.A., Fari\u00f1as, F., Lodeiro, C., Garc\u00eda Alonso, L., Cacabelos, R. GRF-induced GH response in children with short stature and CNS disorders. International Symposium on Growth and Reproduction, Lugo, June 27, pp. 29 (1989). \r\n\r\nFern\u00e1ndez, M., P\u00e9rez, A., Albarr\u00e1n, M.A., Couto, D.F., Cacabelos, R. Age- and sex-related changes in brain histamine. Abstr. 12th Ann. Meet. Eur. Neurosci. Assoc. Turin 2-7 sept., 1989. Eur. J. Neurosci., Suppl. 2:22 (1989), \r\n\r\n\u00c1lvarez, X.A., Couto, D.F., Amigo, M.E., Fandi\u00f1o, J.M., Ares, Y., Garrote, A., Cacabelos, R. Short-term memory improvement after GRF(1-29)NH2 administration in humans. Abstr. 12th Ann. Meet. Eur. Neurosci. Assoc., Turin 2-7 Sept. 1989. Eur. J. Neurosci., Suppl. 2:210 (1989). \r\n\r\nCacabelos, R., Yamatodani, A., Niigawa, H., Wada, H., Nishimura, T., Brandeis, L., Pearson, J. High levels of brain histamine in Alzheimer\u2019s disease. Abstr. 12th Ann. Meet. Eur. Neurosci. Assoc., Turin 2-7 Sept. 1989. Eur. J. Neurosci., Suppl. 2:238 (1989). \r\n\r\n\u00c1lvarez, X.A., Niigawa, H., Nishimura, T., Cacabelos, R. Behavioral changes induced by pharmacological manipulation of the histaminergic system. 21st Ann. Meet. Eur. Brain Behav. Soc., Turin 6-8 Sept. 1989. Eur. J. Neurosci., Suppl. 2:309 (1989). \r\n\r\nCacabelos, R., Di\u00e9guez, C., Niigawa, H., Nishimura, T., Brandeis, L., Scanlon, M.F., Pearson, J. Growth hormone-releasing factor in Alzheimer\u2019s disease. 21st Ann. Meet. Eur. Brain Behav. Soc., Turin 6-8 Sept. 1989. Eur. J. Neurosci., Suppl. 2:311 (1989). \r\n\r\nFern\u00e1ndez, M., Otero, F., \u00c1lvarez, X.A., Ver\u00edsimo, J., Serrano, F., P\u00e9rez, T., Rodr\u00edguez, A., Cacabelos, R. GRF-induced GH response in patients with heart disease and chronic alcoholism. 21st Ann. Meet. Eur. Brain Behav. Soc., Turin 6-8 Sept. 1989. Eur. J. Neurosci., Suppl. 2:313 (1989). \r\n\r\nFern\u00e1ndez, M., P\u00e9rez, A., Rubia, F.J., Cacabelos, R. Chrononeurobiology of the histaminergic system. Abstr. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife 8-10 dic. 1988. Pfl\u00fcgers Archiv. Eur. J. Physiol., 414: (1989). \r\n\r\n\u00c1lvarez, X.A., Albarr\u00e1n, M.A., Niigawa, H., Rubia, F.J., Cacabelos, R. Behavioral changes after pharmacological manipulation of the histaminergic system. A computerized analysis. Abstr. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife 8-10 dic. 1988. Pfl\u00fcgers Archiv. Eur. J. Physiol., 414; (1989). \r\n\r\nCacabelos, R., Ortiz, T., Rubia, F.J. Neurochemical markers for Alzheimer\u2019s disease. Abstr. XXIll Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife 8-10 dic. 1988. Pfl\u00fcgers Archiv. Eur. J. Physiol., 414:S24 (1989). \r\n\r\nOrtiz, T., Cacabelos, R., Rubia, F.J. Brain electrical activity mapping in Alzheimer\u2019s disease. Abstr. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife 8-10 dic. 1988. Pfl\u00fcgers Archiv. Eur. J. Physiol., 414:S23 (1989). \r\n\r\nOtero, F., \u00c1lvarez, J.A., Rubia, F.J., Cacabelos, R. Interaction between histaminergic (HAS) and somatotropinergic system (STS) at the central level. Abstr. XXIII Cong. Nac. Soc. Esp. Cienc. Fisiol., Tenerife 8-10 dic. 1988. Pfl\u00fcgers Archiv. Eur. J. Physiol., 414:S16 (1989). \r\n\r\nOtero, F., \u00c1lvarez, X.A., Agra, S., Alonso, J., Tabernero, J., Tortajada, I., Cacabelos, R. Respuesta de GH a GRF en pacientes con esquizofrenia. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 247 (1989). \r\n\r\nP\u00e9rez, A., Albarr\u00e1n, A., \u00c1lvarez, X.A., Fern\u00e1ndez, M., Otero, F.O., Cacabelos, R. Estudios neuroqu\u00edmicos preliminares sobre la demencia postmenop\u00e1usica tipo Alzheimer. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 247 (1989). \r\n\r\nAlbarr\u00e1n, M.A., del Pino, J.L., M\u00edgmel, F., Mart\u00edn-Loeches, M., Exp\u00f3sito, F.J., Rubia, F.J., Cacabelos, R. Respuesta de GH a GRF en trastornos por d\u00e9ficit de atenci\u00f3n con hiperquinesia. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 248 (1989). \r\n\r\n\u00c1lvarez, X.A., Couto, D.F., Fern\u00e1ndez, M., Otero, F., Albarr\u00e1n, M., P\u00e9rez, A., Cacabelos, R. Influencia del sistema somatotropin\u00e9rgico (SST) sobre funciones cognitivas. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 248 (1989). \r\n\r\nCacabelos, R., Di\u00e9guez, C., Niigawa, H., Nishimura, T., Brandeis, L., Scanlon, M.F., Pearson, J. Alteraciones selectivas de somatoliberina (GRF) en el SNC de pacientes con enfermedad de Alzheimer. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 249 (1989). \r\n\r\nFern\u00e1ndez, M., Cacabelos, R. Respuesta de GH a GRF en anorexia nerviosa. III Congr. Nac. Soc. Esp. Neurociencia. Sevilla 2-5 Oct., pp. 249 (1989). \r\n\r\nCacabelos, R. Disfunci\u00f3n amino-peptid\u00e9rgica en la enfermedad de Alzheimer. Nuevos hallazgos neuroqu\u00edmicos. Simposium sobre \u201cBases neuroqu\u00edmicas del envejecimiento cerebral: Enfermedad de Alzheimer\u201d. Granada 6-7 Oct. (1989). \r\n\r\nAlbarr\u00e1n, M.A., P\u00e9rez, A., Fern\u00e1ndez, M., Otero, F., \u00c1lvarez, J.A., Borr\u00e1s, C., Rodr\u00edguez, A., Cacabelos, R. GRF test: A potential diagnostic marker in psychiatric disorders. VIII World Congr. Psychiatry. Athens, 12-19 Oct. Psychiatry Today. Accomplishments and Promises. Excerpta Medica. International Congress Series 899:341 (1989). \r\n\r\nCacabelos, R., Di\u00e9guez, C., Niigawa, H., Nishimura, T., Scanlon, M.F., Pearson, J. Growth hormone-releasing factor (GRF) in senile dementia. VIII World Congr. Psychiatry. Athens, 12-19 Oct. Psychiatry Today. Accomplishments and promises. Excerpta Medica. International Congress Series 899:730 (1989). \r\n\r\nCacabelos, R., Yamatodani, A., Niigawa, H., Wada, H., Nishimura, T., Pearson, J. Brain histamine in senile dementia. VIII World Congr. Psychiatry. Athens, 12-19 Oct. Psychiatry Today. Accomplishments and Promises. Excerpta Medica. International Congress Series 899:730 (1989). \r\n\r\nRodr\u00edguez, A., Mateos, R., Cacabelos, R. Diagn\u00f3stico y estrategias de seguimiento en demencias. VIII World Congr. Psychiatry. Athens, 12-19 Oct. Psychiatry Today. Accomplishments and Promises. Excerpta Medica. International Congress Series 899:730 (1989).\r\n\r\nP\u00e9rez, A., Albarr\u00e1n, M., \u00c1lvarez, X.A., Fern\u00e1ndez, M., Otero, F., Cornes, J.M., Rodr\u00edguez, A., Cacabelos, R. GRF-induced GH response in Alzheimer\u2019s disease. VIII World Congr. Psychiatry. Athens, 12-19 Oct. Psychiatry Today. Accomplishments and promises. Excerpta Medica. International Congress Series 899:735 (1989). \r\n\r\nCacabelos, R., Di\u00e9guez, C., Niigawa, H., Scanlon, M.F., Pearson, J., Nishimura, T. Growth hormone-releasing factor (GRF) in Alzheimer\u2019s disease. Alzheimer\u2019s and Parkinson\u2019s diseases. Basic and therapeutic strategies. The second International Conference. Kyoto, 6-10 Nov. (1989). \r\n\r\nCacabelos, R. Marcadores neurol\u00f3gicos en alcoholismo. XIV Reun. Nac. Soc. Esp. Psiquiat. Biol., Santander, 2-3 Nov, 1989. Anales Psiquiatr\u00eda, 5(Supl.II):3-4 (1989). \r\n\r\n\u00c1lvarez, X.A., Couto, D.F., Cacabelos, R. Efectos de somatoliberina (GRF(1-29)NH2) y GH biosint\u00e9tica (Saizen) sobre actividad psicomotriz en ratas. X1V Reun. Nac. Soc. Esp. Psiquiat Biol., Santander, 2-3 Nov. 1989. Anales Psiquiatr\u00eda 5(Supl.II):49-50 (1989). \r\n\r\nAlbarr\u00e1n, M.A., Salazar, I., P\u00e9rez, I., Rodr\u00edguez, A., Cacabelos, R. Hiporrespuesta de GH a GRF en toxic\u00f3manos. XIV Reun, Nac. Soc. Esp. Psiquiat. Biol., Santander, 2-3 Nov. 1989. Anales Psiquiatr\u00eda 5(Supl. II):50 (1989). \r\n\r\nP\u00e9rez, A., Fern\u00e1ndez, M., Cornes, J.M., Albarr\u00e1n, M.A., Cacabelos, R. Respuesta de GH a GRF (growth hormone-releasing factor) en pacientes con demencia multiinfarto (DM1). XIV Reun. Nac. Soc. Esp. Psiquiat. Biol., Santander, 2-3 Nov. 1989. Anales Psiquiatr\u00eda 5(Supl. II):50-51 (1989). \r\n\r\nFern\u00e1ndez, M., Albarr\u00e1n, M.A., Cornes, J.M., Cacabelos, R. Respuesta de GH a GRF en trastornos depresivos. XIV Reun. Nac. Soc. Esp. Psiquiat. Biol., Santander, 2-3 Nov. 1989. Anales Psiquiatr\u00eda, 5(Supl.II):51 (1989). \r\n\r\nOtero, F., Tortajada, I., Alonso, J., Blanco, J., Tabernero, J., Agra, S., Cornes, J.M., Cacabelos, R, Test de GRF: Potencial marcador diagn\u00f3stico en esquizofrenia. XIV Reun. Nac. Soc. Esp. Psiquiat. Biol., Santander, 2-3 Nov. 1989. Anales Psiquiatr\u00eda 5(Supl.II):51-52 (1989). \r\n\r\nCacabelos, R. Bases neurobiol\u00f3gicas de los trastornos depresivos. Symposium. Avances en patolog\u00eda depresiva. Oviedo, 1 Dic. (1989). \r\n\r\nNiigawa, H., Cacabelos, R., Hariguchi, S., Nishimura, T. Changes in CAT activity and VP content in the aging rat brain. Jpn. J. Geriat., 26:134 (1989). \r\n\r\nNiigawa, H., Cacabelos, R., Hariguchi, S., Nishimura, T. Effects of i.c.v. injections of arginine-vasopressin on rat behavior. Step-down type passive avoidance behavior studied in the OUCEM-86. Psychopharmacology Abstract Book, pp. 108 (1989). \r\n\r\nCacabelos, R. Growth hormone-releasing factor (GRF): Neurobiology and applications in clinical neuroscience. Emil Aaltonen Symposium. Healthy Brain. Tampere, Finland, 22.3.90. Tampereen Laakaripaivat-90, Luennot 11:81-82 (1990). \r\n\r\nCacabelos, R. Alzheimer\u2019s disease: Update. Physiopathology. Advances in Psychiatry 90. Amsterdam, 19.4.90. \r\n\r\nCacabelos, R., Fern\u00e1ndez, M., Fari\u00f1as, F., Otero, F., Rubia, F.J. Histidine decarboxylase (HDC) inhibition induced by \uf061-FMH provokes learning-related hypokinetic activity. XIX Meeting Eur. Histamine Res. Soc., Kuopio (Finland), 16-20 Mayo, pp. 9 (1990). \r\n\r\nCacabelos, R., Niigawa, H., Rivier, J., Vale, W. Brain histamine synthesis blockade with \uf061-FMH dysregulates the corticotropinergic system: Influence of \uf061-FMH and adrenalectomy (ADX) on CRF. XIX Meeting Eur. Histamine Res. Soc., Kuopio (Finland), 16-20 Mayo, pp. 41 (1990). \r\n\r\nCacabelos, R. Nuevas estrategias terap\u00e9uticas en la enfermedad de Alzheimer: Factores neurotr\u00f3ficos, neurop\u00e9ptidos y agentes nootropos. II Reuni\u00f3n Nac. Soc. Esp. Gerontopsiquiat. Psicogeriat., Oviedo, 31 Mayo-2 Junio (1990), \r\n\r\nCacabelos, R. Bases gen\u00e9ticas de los trastornos mentales y marcadores neuroqu\u00edmicos. Jornada Cient\u00edfica. La psiquiatr\u00eda en el contexto de las neurociencias actuales. Pazo de Mari\u00f1\u00e1n, La Coru\u00f1a, 9 Junio (1990). \r\n\r\nCacabelos, R. Eficacia de fluoxetina en el contexto de los ensayos cl\u00ednicos. V Jornada Cient\u00edfica, Asoc. Gallega Psiquiatr\u00eda. Estado actual del tratamiento de la depresi\u00f3n. La Coru\u00f1a, 22 Junio (1990).\r\n\r\n\u00c1lvarez, X.A., Cacabelos, R. Behavioral changes induced by peripheral manipulation of the somatotropinergic system. 2nd Int. Cong. Neuroendocrinology, Bordeaux, France, June 24-29, 1990. Neuroendocrinology, 52 (Suppl. 1):64 (1990). \r\n\r\nCacabelos, R. Estrategias con neurop\u00e9ptidos (NPs) y factores neurotr\u00f3ficos en la enfermedad de Alzheimer (EA). Simposio Multidisciplinario sobre Enfermedad de Alzheimer y otras Demencias. Pamplona, 16-19 Sept., pp. 31 (1990). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Cacabelos, R. Interleukina-l (IL-1) en la enfermedad de Alzheimer. Simposio Multidisciplinario sobre Enfermedad de Alzheimer y otras Demencias. Pamplona, 16-19 Sept., pp. 45 (1990). \r\n\r\nCacabelos, R. Neurobiolog\u00eda del GRF: Aspectos b\u00e1sicos y cl\u00ednicos. Symposium Sat\u00e9lite de Neurobiolog\u00eda. XXIV Congr. Nac. Soc. Esp. Cienc. Fisiol., Madrid, 24-25 Sept., N-3 (1990). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Mallo, F., Cacabelos, R. Estudios sobre actividad locomotriz y aprendizaje de evitaci\u00f3n pasiva en ratas con dieta deficiente en vitamina A. XXIV Congr. Nac. Soc. Esp. Cienc. Fisiol., Madrid 26-29 Sept., 130 (1990). \r\n\r\nFranco, A., \u00c1lvarez, X.A., Mallo, F., Cacabelos, R. Efectos de GHRP-6 sobre actividad locomotriz y aprendizaje de evitaci\u00f3n pasiva en ratas. XXIV Congr. Nac. Soc. Esp. Cienc. Fisiol., Madrid 26-29 Sept., 131 (1990). \r\n\r\nCacabelos, R. Neurobiolog\u00eda del GRH: Aspectos b\u00e1sicos y cl\u00ednicos. Psiconeuroendocrinolog\u00eda. Jornadas de Endocrinolog\u00eda. Consejo General de M\u00e9dicos, Madrid 18 Oct., (1990). \r\n\r\nCacabelos, R. Bases neurofisiol\u00f3gicas de la ansiedad y depresi\u00f3n. I Reuni\u00f3n da Sociedade Galega de Xerontolox\u00eda e Xeriatr\u00eda. A Toxa, Pontevedra, 19-21 Oct., (1990). \r\n\r\nCacabelos, R., \u00c1lvarez, X.A. Funci\u00f3n neuroinmune en trastornos mentales. XV Reuni\u00f3n Nacional Soc. Esp. Psiquiat. Biol., C\u00f3rdoba 1-3 Nov., 1990. An. Psiq., 6 (Supl.II):13 (1990). \r\n\r\nCacabelos, R. Neuroqu\u00edmica y marcadores biol\u00f3gicos en las demencias. XV Reuni\u00f3n Nac. Soc. Esp. Psiquiat. Biol., C\u00f3rdoba 1-3 Nov., 1990. Simposio Actualizaci\u00f3n en las demencias. 2 Nov. (l990) \r\n\r\nCacabelos, R., Franco-Maside, A., \u00c1lvarez, X.A. Bases neurobiol\u00f3gicas y psicopatolog\u00eda del complejo demencia-SIDA. Jornadas sobre SIDA y Salud Mental. Zaragoza 16-17 Nov. (1990). \r\n\r\nFranco, A., \u00c1lvarez, X.A., Mallo, F., D\u00edaz, E., Cacabelos, R. Deterioro del aprendizaje por evitaci\u00f3n pasiva en ratas con dieta deficiente en \u00e1cido retinoico. X Congr. Nac. Soc. Esp Endocrinolog\u00eda. Santiago de Compostela, 5-7 Junio, 1991. Endocrinolog\u00eda, 38(Supl.2):39 (1991). \r\n\r\n\u00c1lvarez, X., Franco, A., Mallo, F., D\u00edaz, E., Cacabelos, R. Efecto del hexap\u00e9ptido liberador de hormona de crecimiento (GHRP-6) sobre conducta en ratas. X Congr. Nac. Soc. Esp. Endocrinolog\u00eda. Santiago de Compostela, 5-7 Junio, 1991. Endocrinolog\u00eda, 38(Supl.2);44-45 (1991). \r\n\r\nFranco-Maside, A., \u00c1lvarez, X.A., Cacabelos, R. Atrial natriuretic peptide in Alzheimer\u2019s disease. 5th World Congr. Biol. Psychiatry, Florence, Italy, June 9-14, 1991. Biol. Psychiatry 29\/11S:479S-480S (1991). \r\n\r\n\u00c1lvarez, X.A., Franco-Maside, A., Cacabelos, R. GRF-induced GH response in Alzheimer\u2019s disease (AD), multi-infarct dementia (MID), and pseudodementia (PD). 5th World Congr. Biol. Psychiatry, Florence, Italy, June 9-14, 1991. Biol. Psychiatry, 29\/l l S:685S (1991). \r\n\r\nCacabelos, R., Franco-Maside, A., \u00c1lvarez, X.A. Interleukin-l (IL-1) in Alzheimer\u2019s disease (AD). 5th World Congr. Biol, Psychiatry, Florence, Italy, June 9-14, 1991. Biol. Psychiatry, 29\/11S:687S (1991). \r\n\r\nCacabelos, R., Barquero, M., Garc\u00eda, P., \u00c1lvarez, X.A., Varela de Seijas, E. Cerebrospinal fluid interleukin 1\uf062 in Alzheimer\u2019s disease. XXII Congr. Intern. Soc. Psychoneuroendocrinology, Siena, Italy, June 17-20, 1991. Neuroendocr. Lett., 13 :206 (1991). \r\n\r\nFranco, A., \u00c1lvarez, X.A., Cacabelos, R. Acute effects of growth hormone releasing factor (GRF) on cognitive function in aging and senile dementia. XXII Congr. intern. Soc. Psychoneuroendocrinology, Siena, Italy, June 17-20, 1991. Neuroendocr. Lett., 13:213 (1991). \r\n\r\n\u00c1lvarez, X.A., Vara, E., Barquero, M., Garc\u00eda, P., Moreno, A., Varela de Seijas, E., Cacabelos, R. Cerebrospinal fluid (CSF) insulin in Alzheimer\u2019s disease. XXII Congr. Intern. Soc. Psychoneuroendocrinology. Siena, Italy, June 17-20, 1991. Neuroendocr. Lett., 13:249 (1991). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez, L., Caso, J., Cacabelos, R. Interleukin-l in senile dementia. Correlation with physiological and cognitive parameters. Il Eur. Congr. Gerontol., Madrid 11-14 Sept., 1991. Rev. Esp. Geriat. Gerontol., 26 (Supl.1):202 (1991). \r\n\r\nFranco, A., \u00c1lvarez, X.A., Caso, J., Fern\u00e1ndez, L., Cacabelos, R. Atrial natriuretic peptide in senile dementia. Il Eur. Congr. Gerontol., Madrid 11-14 Sept., 1991. Rev. Esp. Geriat. Gerontol., 26 (Supl. 1):202 (1991). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Caso, J., Fern\u00e1ndez, L., Cacabelos, R. GRF-induced GH response in senile dementia. Correlation between neurophysiological and neuroendocrine parameters. II Eur. Congr. Gerontol., Madrid 11-l4 Sept., 1991. Rev. Esp. Geriat. Gerontol., 26 (Supl. l):203 (l99l). \r\n\r\nCacabelos, R. Brain histamine: Neuroendocrine regulator in physiological and pathological conditions. Symposium Biogenic Amines. 1st Int. Cong. Vitamins and Biofactors in Life Sciences (ICVB): Kobe, Japan, Sept. 16-20; pp. 53 (1991). \r\n\r\nCacabelos, R., \u00c1lvarez, X.A. Environmental factors, development and cognition: Influence of the somatotropinergic system (STS) on mental function and psychomotor activity. VIth Int. Congr. Auxology. Madrid, 15-19 Sept. (1991). \r\n\r\nP\u00e9rez-Trull\u00e9n, J.M., V\u00e1zquez-Andr\u00e9, M.L., \u00c1lvarez, X.A., Cacabelos, R. La onda P300 como m\u00e9todo diagn\u00f3stico en la enfermedad de Alzheimer. IV Congr. Soc. Esp. Neurociencia. Alicante 30.9-3.10, 25.16-P (1991). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Mallo, F., D\u00edaz, E., Cacabelos, R. El tratamiento con testosterona revierte el deterioro del aprendizaje inducido por d\u00e9ficit de \u00e1cido retinoico en ratas. IV Cong. Soc. Esp. Neurociencia, Alicante 30.9-3.10, 32-16-P (1991). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Cacabelos, R. Efectos del GRF(1- 29)NH2 sobre funci\u00f3n cognitiva en la demencia senil. IV Cong. Soc. Esp. Neurociencia, Alicante 30.9-3.10, 32-17P (1991). \r\n\r\nCacabelos, R. Marcadores gen\u00e9ticos en Psiquiatr\u00eda. XVI Reun. Nac. Soc. Esp. Psiquiatr\u00eda Biol\u00f3gica, Vitoria, 7-9 Nov., (1991). \r\n\r\nFranco, A., \u00c1lvarez, X.A., G\u00f3mez-Trigo, J., Caama\u00f1o, J., Cacabelos, R. Influencia del GRF sobre funci\u00f3n mental en la demencia senil. XVI Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: 111 (1991).\r\n\r\n\u00c1lvarez, X.A., Franco, A., G\u00f3mez-Trigo, J., Caama\u00f1o, J., Cacabelos, R. Interleucina-1 central y perif\u00e9rica en la demencia senil. XVI Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: 111 (1991). \r\n\r\n\u00c1lvarez, X.A., Franco, A., G\u00f3mez-Trigo, J., Caama\u00f1o, J., Vara, E., Barquero, M., Garc\u00eda, P., Moreno, A., Varela de Seijas, E., Cacabelos, R. Insulina central en la demencia senil. XVI Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: 112 (1991). \r\n\r\nP\u00e9rez-Trull\u00e9n, J.M., V\u00e1zquez Andr\u00e9, M.L., Cacabelos, R. Estudio de la prosodia en la enfermedad de Alzheimer. XVI Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: 113 (1991). \r\n\r\nP\u00e9rez-Trull\u00e9n, J.M., V\u00e1zquez Andr\u00e9, M.L., Caso, J., \u00c1lvarez, X.A., Franco, A., Cacabelos, R. Alteraciones del lenguaje en la enfermedad de Alzheimer. XV1 Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: l l3 (1991). \r\n\r\nP\u00e9rez-Trull\u00e9n, J.M., V\u00e1zquez-Andr\u00e9, M.L., Modrego, A., \u00c1lvarez, X.A., Cacabelos, R. Trastornos de memoria y P300 en la enfermedad de Alzheimer. XVI Reun. Nac. Soc. Esp. Psiquiat. Biol., Vitoria, 7-9 Nov., 1991. Anales Psiquiatr\u00eda, 7: 114 (1991), \r\n\r\nCacabelos, R. Nuevos aspectos de la etiopatogenia de la enfermedad de Alzheimer. Workshop internacional. Envejecimiento y Farmacolog\u00eda Preventiva. Alicante, 13-14 Dic., (1991). \r\n\r\nCacabelos, R. Psicofarmacolog\u00eda molecular de la enfermedad de Alzheimer, Nuevas estrategias terap\u00e9uticas. IV Congr. Intern. Farmacoterapia y Nutrici\u00f3n Geri\u00e1trica, Valencia, 26-29.2.92 (1992). \r\n\r\nCacabelos, R. Neurobiolog\u00eda molecular de la enfermedad de Alzheimer. Prospecciones terap\u00e9uticas. I Symposium de Psicobiolog\u00eda. Perspectivas Actuales de Investigaci\u00f3n en Psicobiolog\u00eda. La Coru\u00f1a, 9-13.3.92 (1992). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. GRF-induced GH response in opiate addicts. Int. Meeting. Strategies for studying CNS active compounds: Models, screens and clinical syndromes. Madrid, 26 April-2 May, 1992. Behav. Pharmacol., 3(Suppl. 1):60 (1992). \r\n\r\nFern\u00e1ndez-Novoa, L., Pastuzko, A., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Effects of neurocatin on the release and level of serotonin in synaptosomes from the rat brain. Int. Meeting. Strategies for studying CNS active compounds: Models, screens and clinical syndromes. Madrid, 26 April-2 May, 1992. Behav. Pharmacol., 3(Suppl. 1):94 (1992). \r\n\r\nFern\u00e1ndez-Novoa, L., Pastuszko, A., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. The effects of neurocatin on serotonin metabolism in synaptosomes from the rat brain. Int. Meeting. Strategies for studying CNS active compounds: Models, screens and clinical syndromes. Madrid, 26 April-2 May, 1992. Behav. Pharmacol., 3(Suppl. 1):94-95 (1992). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Positive effects of GHRP-6 on passive avoidance behavior in a new experimental paradigm. Int. Meeting. Strategies for studying CNS active compounds: Models, screens and clinical syndromes. Madrid, 26 April-2 May, 1992. Behav. Pharmacol., 3(Suppl. 1):84-85 (1992). \r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., Franco-Maside, A., \u00c1lvarez, A. Neuroendocrine and neuroimmune modulatory effects of brain histamine: physiological responses and pathological implications in Alzheimer\u2019s disease. XXI Ann. Meeting European Histamine Research Society. Torremolinos, M\u00e1laga, 13-17 May, 1992, pp. 90 (1992). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of betahistine on locomotor activity and passive avoidance behavior in rats. XXI Ann. Meeting European Histamine Research Society. Torremolinos, M\u00e1laga, l3-17 May, pp. 95 (1992). \r\n\r\nCacabelos, R. Funci\u00f3n neuroinmune en trastornos mentales: papel de la histamina cerebral como neuroinmunomodulador en condiciones fisiol\u00f3gicas y patol\u00f3gicas. XII Congr. Asoc. Latinoamer. Soc. Biol. Med. Nuclear. Madrid, Mayo 25-28 (1992). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Dose- and time-dependent effects of histamine on hypothalamic levels of interleukin-1\uf062 in rats. XXI Ann. Meeting European Histamine Research Society. Torremolinos, M\u00e1laga, 13-17 May, pp. 107 (1992). \r\n\r\nCacabelos, R. Hacia un tratamiento etiopatog\u00e9nico de la enfermedad de Alzheimer: Psicofarmacolog\u00eda molecular. Mesa Redonda: Nuevas alternativas terap\u00e9uticas en la enfermedad de Alzheimer, III Congr. Nac. Soc. Esp. Psiquiat. Biol., Pamplona 17-20 Junio, pp. 63-64 (1992). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Efectos positivos de la betahistina sobre el deterioro del aprendizaje inducido por escopolamina en ratas. III Congr. Nac. Soc. Esp. Psiquiat. Biol., Pamplona 17-20 Junio, pp. 259-260 (1992). \r\n\r\nFranco, A., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Efectos del tratamiento con citicolina sobre funci\u00f3n cognitiva y niveles s\u00e9ricos de interleucina-1\uf062 en la demencia senil, III Congr. Nac. Soc. Esp. Psiquiat. Biol., Pamplona 17-20 Junio, pp. 260-261 (1992). \r\n\r\nCaama\u00f1o, J., Valle-lncl\u00e1n, F., Cacabelos, R. Velocidades de flujo sangu\u00edneo en arteria cerebral media de pacientes con demencia vascular: evaluaci\u00f3n mediante ultrasonograf\u00eda Doppler transcraneal. III Congr. Nac. Soc. Esp. Psiquiat. Biol., Pamplona 17-20 Junio (1992). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Age- and sex-related serum growth hormone (GH) levels in psychiatric patients and healthy control subjects. A correlation study between GH values and cognitive performance. Proc. 18th Collegium Internationale Neuro- Psychopharmacologicum Congress. Nice, June 28-July 2, 1992. Clin. Neuropharm., 15(Suppl. 1-B);283B (1992). \r\n\r\nCacabelos, R., Franco-Maside, A., \u00c1lvarez, X.A. Therapeutic effects of CDP-Choline on cognition and cardiovascular parameters in Alzheimer\u2019s disease. Proc. 18th CINP Congress, Nice, June 28-July 2, 1992. Clin. Neuropharmacol., 15(Suppl. 1-B):474B (1992). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of betahistine on behavior in rats. Preliminary results. Proc. 18th CINP Congress, Nice, June 28-July 2, 1992. Clin. Neuropharmacol., 15(Suppl. 1-B) :478B (1992). \r\n\r\nFern\u00e1ndez-Novoa, L., Pastuszko, A., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Inhibition of monoamine oxidase A by neurocatin in synaptosomes from rat brain. Proc. 18th CINP Congress, Nice, June 28-July 2, 1992. Clin. Neuropharmacol., 15(Suppl. 1-B):590B (1992).\r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Franco-Maside, A., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F. Influence of CDP-Choline on cognition and interleukin-1\uf062 in Alzheimer\u2019s disease (AD) and multi-infarct dementia (MID). The Third International Conference on Alzheimer\u2019s Disease and Related Disorders. Padova, July 12-17, 1992. Neurobiol. Aging 13(Suppl. 1):S134-S135 (1992). \r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F., Secades, J., Novell, R., Lozano, R. Therapeutic effects of CDP-Choline in Alzheimer\u2019s disease and multi-infarct dementia. International Conference on Neurodegenerative Disease. New Approaches to Treatment. London. 15-16 Sept., 1992.\r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F., Secades, J., Novell, R., Lozano, R. Effects of CDP-Choline in Alzheimer\u2019s disease and multi-infarct dementia: Influence on cognition, mood, and interleukin-\uf062 production. 8th lnt. Meeting and Conference. Alzheimer Disease International (ADI). Brussels, Sept. 25-27 (1992). \r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F., Secades, J., Novell, R., Lozano, R. Therapeutic effects of CDP-Choline in Alzheimer\u2019s disease and multi-infarct dementia. Int. Conf. Neurodegenerative Disease. New Approaches to Treatment. London, Sept. 15-16 (1992). \r\n\r\nCacabelos, R. Basic mechanisms and classification of memory disorders with special reference to dementias. Workshop: Technical aids for memory and environmental control in dementia and other cognitive impairment. NORAGE \u201992. First Congress of the Nordic Society for Research in Brain Aging. Sheraton Copenhagen Hotel, Copenhagen, Denmark, Oct. 9-10 (1992). \r\n\r\nCacabelos, R. Estrategias terap\u00e9uticas en la enfermedad de Alzheimer. Avances en la enfermedad de Alzheimer y relaci\u00f3n de A.F.A.F. con las l\u00edneas de investigaci\u00f3n en Espa\u00f1a. 1\u00aa Reuni\u00f3n Asociaci\u00f3n Familiares de Alzheimer de Andaluc\u00eda y 1\u00ba Congreso de la Federaci\u00f3n Espa\u00f1ola de Asociaciones de Familiares de enfermos de Alzheimer. M\u00e1laga, Oct. 1-2 (1992). \r\n\r\nValle-lncl\u00e1n, F., Caama\u00f1o, J., Cacabelos, R. Functional relationship between blood-flow velocity in middle cerebral artery and EEG spectral analysis. Vth Congr. Eur. College Neuropsychopharmacology. Marbella, 18-21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:326 (1992). \r\n\r\nFranco, A., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Betahistine attenuates learning impairment induced by scopolamine in rats. Vth Congr. Eur. College Neuropsychopharmacology. Marbella, 18-21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:354 (1992). \r\n\r\nCaama\u00f1o, J., Valle-lncl\u00e1n, F., Cacabelos, R. Parieto-temporal hypoperfusion in Alzheimer\u2019s disease measured by transcranial doppler ultrasonography. Vth Congr. Eur. College Neuropsychopharmacology. Marbella, 18-21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:360 (1992). \r\n\r\nFern\u00e1ndez-Novoa, L., P\u00e9rez-Trull\u00e9n, J.M., Cacabelos, R. Serum histamine in Alzheimer\u2019s disease and multi-infarct dementia. Vth Congr. Eur. College Neuropsychopharmacology, Marbella 18- 21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:360 (1992). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Central and peripheral interleukin-l in Alzheimer\u2019s disease. Vth Congr. Eur. College Neuropsychopharmacology, Marbella 18- 21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:361-362 (1992). \r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Franco-Maside, A., Fern\u00e1ndez- Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F. Effect of CDP-Choline on cognition and immune function in Alzheimer\u2019s disease and multi-infarct dementia. Vth Congr. Eur. College Neuropsychopharmacology, Marbella 18-21 Oct. 1992. Eur. Neuropsychopharmacol., 2\/3:362-363 (1992). \r\n\r\nG\u00f3mez, M.J., \u00c1lvarez, X.A., Cacabelos, R. Dementia Mood Assessment Scale in elderly controls and in patients with depression and\/or cognitive impairment. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov., 1992. Anales Psiquiatr\u00eda 8(Supl. 1):102 (1992). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Serum growth hormone (GH) levels in psychiatric patients. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov., 1992. Anales Psiquiatr\u00eda, 8(Supl.1)106 (1992). \r\n\r\nCaama\u00f1o, J., Valle-lncl\u00e1n, F., Cacabelos, R. Blood flow velocity in multi-infarct dementia and Alzheimer\u2019s disease: Neuropsychological correlations. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov., 1992. Anales Psiquiatr\u00eda, 8(Supl.1):107-108 (1992). \r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Franco, A., G\u00f3mez, M.J., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F. Influence of CDP-Choline on cognitive parameters in Alzheimer\u2019s disease and multi-infarct dementia. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov., 1992. Anales Psiquiatr\u00eda, 8(Supl.1):108 (1992). \r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., Franco, A., \u00c1lvarez, X.A. Serum histamine and tumor necrosis factor (TNF) in Alzheimer\u2019s disease and multi-infarct dementia. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov. 1992. Anales Psiquiatr\u00eda, 8(Supl.1):108 (1992). \r\n\r\nFranco, A., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Serum interleukin-1p in control subjects and senile dementia. 6th Eur. Congr. Assoc. Eur. Psychiat., Barcelona 3-7 Nov. 1992. Anales Psiquiatr\u00eda, 8(Supl.1):109 (1992).\r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Franco-Maside, A., Fern\u00e1ndez- Novoa, L., Caama\u00f1o, J., Valle-lncl\u00e1n, F. Effect of CDP-Choline on cognition and immune function in Alzheimer\u2019s disease and multi-infarct dementia. Proc. 7th Meeting International Study Group on the Pharmacology of memory disorders associated with aging. Alzheimer\u2019s disease: Amyloid precursor proteins, signal transduction, and neural transplantation. Nitsch, R.M., Growdon, J.H., Corkin, S., Wurtman, R.J., Z\u00fcrich, Switzerland, Feb. 12-14; pp. 391-393 (1993). \r\n\r\nCacabelos, R. Biomedical aspects of Alzheimer\u2019s disease: Introductory remarks. International Workshop on Alzheimer\u2019s disease: Progress for the next decade. Fundaci\u00f3n Ram\u00f3n Areces, March 22-23, 1993.\r\n\r\nCacabelos, R. New trends for an etiopathogenic therapy in Alzheimer\u2019s disease. lnternational Workshop on Alzheimer\u2019s disease: Progress for the next decade. Fundaci\u00f3n Ram\u00f3n Areces. March 22-23, l993. \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Novo, B., Rettori, M.C., Garc\u00eda, M., Cacabelos, R. Effects of S-9977-2 on learning and behavior in rats with neurotoxic lesions in the nucleus basalis of Meynert (NBM). Recent advances in the treatment of neurodegenerative disorders and cognitive dysfunction. Collegium Internationale Neuro-Psychopharmacologicum (CINP) President\u2019s Workshop. Capri (Italy), May 1-3, 1993. pp. 125 (1993). \r\n\r\nG\u00f3mez, M.J., Cacabelos, R. Alzheimer\u2019s Disease Assessment Scale in control elderly subjects and in patients with Alzheimer\u2019s disease or multi-infarct dementia. Recent advances in the treatment of neurodegenerative disorders and cognitive dysfunction. CINP. President\u2019s Workshop. Capri (Italy), May 1-3, pp. 141 (1993). \r\n\r\nFranco-Maside, A., Caama\u00f1o, J., G\u00f3mez, M.J., \u00c1lvarez, A., Fern\u00e1ndez-Novoa, L., Novo, B., Cacabelos, R. CDP-Choline-induced brain mapping changes in patients with Alzheimer\u2019s disease. Recent advances in the treatment of neurodegenerative disorders and cognitive dysfunction. CINP. President\u2019s Workshop. Capri (Italy), May 1-3, pp. 154 (1993). \r\n\r\nCaama\u00f1o, J., Franco, A., G\u00f3mez, M.J., Novo, B., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Acute effects of CDP-Choline on middle cerebral artery blood flow velocities in Alzheimer\u2019s disease: A transcranial Doppler study. Recent advances in the treatment of neurodegenerative disorders and cognitive dysfunction. CINP. President\u2019s Workshop. Capri (Italy), May 1-3, pp. 155 (1993). \r\n\r\nCacabelos, R, Perspectivas actuais do tratamento da demencia de Alzheimer. Demencias: Avan\u00e7os recentes. Actualiza\u00e7ao nos aspectos bioqu\u00edmicos, cl\u00ednicos e terap\u00e9uticos. Hospital de Universidade de Coimbra. Coimbra, Portugal, May 8, 1993. \r\n\r\nCacabelos, R. Enfermedad de Alzheimer: Estrategias diagn\u00f3sticas y terap\u00e9uticas. VIII Congr. Soc. Castellano-leonesa Cantabra de Medicina Interna. Zamora, Mayo 14-15, 1993. Anales Medicina Interna, Extra II, Mayo, pp. 19 (1993). \r\n\r\nCacabelos, R. Role of histamine and interleukin-1 in the neuroimmune dysregulation occurring in Alzheimer\u2019s disease. Eur. Histamine Res. Soc., Cologne, Germany, May 19-22, pp. 7 (1993). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of neurotoxic lesions in histaminergic neurons on psychomotor activity and learning. Eur. Histamine Res. Soc., Cologne, Germany, May 19-22, pp. 70 (1993). \r\n\r\nFern\u00e1ndez-Novoa, L., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Changes in serum histamine and tumor necrosis factor (TNF) from patients with Alzheimer\u2019s disease and multi-infarct dementia. Eur. Histamine Res. Soc., Cologne, Germany, May 19- 22, pp. 89 (1993).\r\n\r\nFern\u00e1ndez-Novoa, L., Franco, A., Lodeiro, C., \u00c1lvarez, X.A., Cacabelos, R. Effects of histamine and alpha-fluoromethylhistidine on brain tumor necrosis factor levels. Eur. Histamine Res. Soc., Cologne, Germany, May 19-22, pp. 90 (1993). \r\n\r\nFranco, A., Fern\u00e1ndez-Novoa, L., Lodeiro, C., \u00c1lvarez, X.A., Cacabelos, R. Effects of histamine and antihistaminics on the hippocampal levels of interleukin-1\uf062 in rats. Eur. Histamine Res. Soc., Cologne, Germany, May 19-22, pp. 91 (1993). \r\n\r\nFern\u00e1ndez-Novoa, L., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Effects of neurotoxic lesions in histaminergic neurons on brain tumor necrosis factor. Eur. Histamine Res. Soc., Cologne, Germany, May 19-22, pp. P-86 (1993). \r\n\r\nCaama\u00f1o, J., Valle-lncl\u00e1n, F., Cacabelos, R. Blood flow velocity in multi-infarct dementia and Alzheimer\u2019s disease studied by transcranial Doppler ultrasonography. World Congr. Gerontology. XVth Congr. Intern. Assoc. Gerontology, Budapest, July 4-9, pp. 301 (1993). \r\n\t \r\n\u00c1lvarez, X.A., Franco, A., Novo, B., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Age-dependent serum interleukin-1 beta levels in healthy control subjects. World Congr. Gerontology. XVth Congr. Intern. Assoc. Gerontology, Budapest, July 4-9, pp. 302 (1993). \r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., P\u00e9rez-Trull\u00e9n, J.M., Franco, A., \u00c1lvarez, X.A. Serum tumor necrosis factor (TNF) in Alzheimer\u2019s disease (AD) and multi-infarct dementia (MID). World Congr. Gerontology. XVth Congr. Intern. Assoc. Gerontology, Budapest, July 4-9, pp. 302 (1993). \r\n\r\nG\u00f3mez, M.J., \u00c1lvarez, X.A., Cacabelos, R. Dementia mood assessment scale in elderly controls and in patients with depression and\/or dementia. World Congr. Gerontology. XVth Congr. Intern. Assoc. Gerontology, Budapest, July 4-9, pp. 302 (1993). \r\n\r\nCacabelos, R. Bases bioqu\u00edmicas del trastorno afectivo bipolar. XVII Reuni\u00f3n Nacional Soc. Esp. Psiquiat. Biol., Salamanca, Junio 16-19 (1993). \r\n\r\nCaama\u00f1o, J., Franco, A., G\u00f3mez, M.J., Novo, B., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Cerebrovascular effects of CDP-choline in patients with Alzheimer\u2019s disease: A transcranial Doppler study. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. \r\n\r\nG\u00f3mez, M.J., Cacabelos, R. Alzheimer\u2019s disease assessment scale in control elderly subjects and in patients with senile dementia. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. \r\n\r\nFranco-Maside, A., Caama\u00f1o, J., Cacabelos, R. Brain electrical activity mapping correlates with cerebral blood flow velocity in Alzheimer\u2019s disease. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. \r\n\r\nCacabelos, R., Miller, D., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Franco-Maside, A., Nishimura, T., Pearson, J. Brain interleukin-1\uf062 in Alzheimer\u2019s disease and vascular dementia. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of Anapsos on psychomotor activity, passive avoidance behavior and brain interleukin-1\uf062 levels. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. \r\n\r\n\u00c1lvarez, X.A., Franco, A., Rettori, M.C., Polo, E., Garc\u00eda, M., Cacabelos, R. Effects of S9977-2 on behavior and brain interleukin-1\uf062 levels in an animal model of cognitive impairment. Sixth Congr. Intern. Psychogeriat. Assoc. (IPA), Berlin, Sept. 5-10, 1993. \r\n\r\nCaama\u00f1o, J., Franco, A., G\u00f3mez, M.J., Novo, B., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Cerebrovascular effects of CDP-choline in patients with Alzheimer\u2019s disease: Hemodynamic parameters measured by transcranial Doppler ultrasonography. 16th Ann. Meeting Eur. Neurosci. Assoc., Madrid, Sept. 18-21, pp. 88, 1993. \r\n\r\nFranco-Maside, A., Caama\u00f1o, J., Cacabelos, R. Brain electrical activity mapping correlates with cerebral blood flow velocity in Alzheimer\u2019s disease. 16th Ann. Meeting Eur. Neurosci. Assoc., Madrid, Sept. 18-21, pp. 89, 1993. \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Franco, A., Cacabelos, R. Influence of brain histamine on interleukin-1\uf062 production in the hypothalamus and hippocampus. 16th Ann. Meeting Eur. Neurosci. Assoc., Madrid, Sept. 18-21, pp. 169, 1993. \r\n\r\nFern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Franco-Maside, A., Caama\u00f1o, J., Cacabelos, R. CDP-choline-induced changes in blood histamine in patients with Alzheimer\u2019s disease. 16th Ann. Meeting Eur. Neurosci. Assoc., Madrid, Sep. 18-21, pp. l l8, 1993. \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Rettori, M.C., Garc\u00eda, M., Cacabelos, R. Time- and dose-dependent effects of S9977 on behavior and brain interleukin-1\uf062. First Int. Congr. on Hormones, Brain and Neuropharmacology, Rhodes, Sept. 13-17, 1993. Neuropsychopharmacology 9\/2S:78S (1993). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of Anapsos on behavior and brain neuroimmune factors. First Int. Congr. on Hormones, Brain and Neuropsychopharmacology, Rhodes, Sept. 13-17, 1993. Neuropsychopharmacology, 9\/2S:164S (1993). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of neurotoxic lesions in histaminergic neurons on behavior and brain cytokines. First Int. Congr. on Hormones, Brain and Neuropsychopharmacology, Rhodes, Sept. 13-17, 1993. Neuropsychopharmacology 9\/2S:164S (1993). \r\n\r\nCacabelos, R. Presente y futuro de la investigaci\u00f3n sobre la enfermedad de Alzheimer. III Congr. Soc. Gallega Gerontolog\u00eda y Geriatr\u00eda, La Coru\u00f1a, Sep. 23-25, 1993. \r\n\r\nCacabelos, R. Enfermedad de Alzheimer: Perspectivas para una d\u00e9cada. Primeres Jornades Geri\u00e0triques, Malatia d\u00b4Alzheimer, Universitat Ramon Llull, Barcelona, Oct. 22-23, 1993. \r\n\r\nCacabelos, R. Neurobiolog\u00eda y gen\u00e9tica molecular de la enfermedad de Alzheimer. Simposium internacional: Perspectivas actuales de la gen\u00e9tica humana. Fundaci\u00f3n Ram\u00f3n Areces, Madrid, Oct. 25-27, 1993. \r\n\r\nFranco-Maside, A., Caama\u00f1o, J., G\u00f3mez, M.J., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Novo, B., Cacabelos, R. CDP-choline-induced brain mapping changes in patients with Alzheimer\u2019s disease. 6th Congr. ECNP, Budapest, Oct. l l-l4, 1993. \r\n\r\nCaama\u00f1o, J., Franco, A., G\u00f3mez, M.J., Novo, B., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Acute effects of CDP-choline on middle cerebral artery blood flow velocities in Alzheimer\u2019s disease: A transcranial Doppler study. 6th Congr. ECNP, Budapest, Oct. 11-l4, 1993. \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Age-related changes in serum interleukin-1\uf062 and tumor necrosis factor-alpha levels in healthy control subjects. 6th Congr. ECNP, Budapest, Oct. 11-14, 1993. \r\n\r\n\u00c1lvarez, X.A., Franco, A., Kamoun, A., Polo, E., Cacabelos, R., Rettori, M.C. S9977-2 reduces learning impairment and brain interleukin-1\uf062 overproduction in rats with neurotoxic lesions in the nucleus basalis of Meynert. 6th Congr. ECNP, Budapest, Oct. 11-14, 1993. \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Effects of Anapsos on behavior and brain neuroimmune function. 6th Congr. ECNP, Budapest, Oct. 11-14, 1993. \r\n\r\nCacabelos, R. Tratamento farmacologico da Doen\u00e7a de Alzheimer: Bases moleculares. Psiquiatr\u00eda: das suas raices aos seus elos de liga\u00e7ao. Figueira da Foz, Oct. 28-30, 1993. \r\n\r\nCacabelos, R. Envejecimiento y demencia en el marco de la atenci\u00f3n primaria. Simposium sat\u00e9lite Bayer. Congr. Soc. Esp. Med. Fam. Comunitaria. La Coru\u00f1a, Nov. 11-13, 1993. \r\n\r\nCacabelos, R. Nuevas alternativas terap\u00e9uticas en las demencias. III Symposium Taller Internacional. Psiquiatr\u00eda, Esquizofrenia y Demencias. A\u00f1o 2000. Tenerife, 28-30 Abril, 1994. \r\n\r\nCacabelos, R. Psicof\u00e1rmacos convencionales en psicogeriatr\u00eda. III Symposium Taller Internacional. Psiquiatr\u00eda, Esquizofrenia y Demencias. A\u00f1o 2000. Tenerife 28-30 Abril, 1994. \r\n\r\nCacabelos, R. New strategies for Alzheimer\u2019s disease treatment: Pleiotropic drugs and multifactorial intervention. Third International Springfield Symposium on Advances in Alzheimer therapy. May 11-15, Springfield, Illinois, pp. 103 (1994). \r\n\r\nCaama\u00f1o, J., G\u00f3mez, M.J., Franco, A., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Novo, B., Vinagre, D., Cacabelos, R. Cerebrovascular and cognitive effects of CDP-choline in patients with Alzheimer\u2019s disease. Third International Springfield Symposium on Advances in Alzheimer Therapy. May 11-15, Springfield, Illinois, pp. 119 (1994). \r\n\r\nFranco-Maside, A., Caama\u00f1o, J., G\u00f3mez, M.J., Vinagre, D., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Novo, B., Zas, R., Cacabelos, R. Effects of CDP-choline in brain electrical activity mapping and cerebral blood flow velocities in Alzheimer\u2019s disease. Third International Springfield Symposium on Advances in Alzheimer Therapy. May 11-l5, Springfield, Illinois, pp. 120 (1994). \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Caama\u00f1o, J., Novo, B., Diaz, J., Sempere, J.M., Cacabelos, R. Effects of Anapsos on behavior and brain neuroimmune factors in rats with neurotoxic lesions in the nucleus basalis of Meynert. Third International Springfield Symposium on Advances in Alzheimer Therapy. May 11-l5, Springfield, Illinois, pp. 122 (1994). \r\n\r\nFern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Zas, R., G\u00f3mez, M.J., Vinagre, D., Sada. G., Cacabelos, R. Effects of Polipodium leucotomos (Difur) on behavior and the hippocampal levels of interleukin-1\uf062, histamine and tumor necrosis factor in nbM-lesioned rats. Third International Springfield Symposium on Advances in Alzheimer Therapy. May 11-15, Springfield, Illinois, pp. 122 (1994). \r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A. Brain histamine in aging and senile dementia. XXIIIrd Annual Meeting European Histamine Res. Soc., Budapest, May 18-21, pp. 4 (1994). \r\n\r\nFern\u00e1ndez-Novoa, L., Zas, R., Deslandes, A., Polo, E., \u00c1lvarez, X.A., Cacabelos, R. Time- and dose-dependent changes induced by S-9977-2 in brain histamine. XXIIIrd Ann. Meet. Eur. Histamine Res. Soc., Budapest, May 18-21, 1994. \r\n\r\nCacabelos, R., Franco-Maside, A., Caama\u00f1o, J., Zas, R., Novo, B., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A. CDP-choline reduces blood histamine levels in Alzheimer\u2019s disease patients. XXIIIrd Ann. Meet. Eur. Histamine Res. Soc., Budapest, May 18-21, 1994. \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Cacabelos, R. Effects of neurotoxic lesions in the nucleus basalis of Meynert on brain histamine. XXIIIrd Ann. Meet Eur. Histamine Res. Soc., Budapest, May 18-21, 1994. \r\n\r\nCaama\u00f1o, J., Franco-Maside, A., Cacabelos, R. Blood histamine correlates with cerebrovascular parameters and quantitative EEG in Alzheimer\u2019s disease. XXIIIrd Ann. Meet. Eur. Histamine Res. Soc., Budapest, May 18-21, 1994. \r\n\r\nCacabelos, R. Enfermedad de Alzheimer. V Symposium Internacional. Centro Neuropsiqui\u00e1trico \u201cSagrado Coraz\u00f3n\u201d. Martorell, Barcelona, 16-18 Junio, 1994. \r\n\r\nCacabelos, R., Sempere, J.M. Factores etiopatog\u00e9nicos en la enfermedad de Alzheimer. Funci\u00f3n inmune. Jornada de Formaci\u00f3n Biom\u00e9dica. Introducci\u00f3n al tratamiento neuroinmune y neurotr\u00f3fico en la enfermedad de Alzheimer. Colegio M\u00e9dicos, Alicante, 10 Junio, 1994. \r\n\r\nCacabelos, R. Estrategias terap\u00e9uticas en la enfermedad de Alzheimer. Jornada de Formaci\u00f3n Biom\u00e9dica. Introducci\u00f3n al tratamiento neuroinmune y neurotr\u00f3fico en la enfermedad de Alzheimer. Colegio M\u00e9dicos, Alicante, 10 Junio, 1994. \r\n\r\nCacabelos, R. Biological markers and the cholinergic hypothesis in Alzheimer\u2019s disease. Putative mechanisms of action of Tacrine. Advances in the management of Alzheimer\u2019s disease. The role of Tacrine. Satellite Symposium. Fourth Meet. Eur. Neurol. Soc., Barcelona, 29 June, 1994. \r\n\r\nFern\u00e1ndez-Novoa, L., Caama\u00f1o, J., Franco-Maside, A., \u00c1lvarez, X.A., Cacabelos, R. Blood histamine correlates with cerebrovascular parameters and brain electrical activity mapping in Alzheimer\u2019s disease. XIXth CINP, Washington DC, June 27-July 1, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, pp. 215S (1994). \r\n\r\nFern\u00e1ndez-Novoa, L., \u00c1lvarez, X,A., Cacabelos, R. CDP-choline-induced blood histamine changes in Alzheimer\u2019s disease. XIXth CINP, Washingon DC, June 27-July l, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, pp. 131S (1994). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Zas, R., Cacabelos, R. Effects of Anapsos on behavior and brain interleukin-1\uf062. XIXth CINP, Washingon DC, June 27-July 1, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, pp. 38S (1994). \r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., Zas, R., Deslandes, A., Garc\u00eda, M., \u00c1lvarez, X.A. Time- and dose-dependent effects of S-9977-2 on brain histamine. XIXth CINP, Washingon DC, June 27- July 1, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, 147S (1994). \r\n\r\nFranco-Maside, A., Caama\u00f1o, J., G\u00f3mez, M.J., Cacabelos, R. Brain mapping activity and mental performance after chronic treatment with CDP-choline in Alzheimer\u2019s disease. XIX CINP, Washingon DC, June 27-July l, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, 216S (1994). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez-Novoa, L., Zas, R., Kamoun, A., Polo, E., Garc\u00eda, M., Cacabelos, R. Behavioral and neuroimmune effects of S-9977-2. XIXth CINP, Washingon DC, June 27-July l, 1994. Neuropsychopharmacology, 10\/3S\/Part 2\/May, 39S (1994). \r\n\r\nCacabelos, R. Therapy for two symptoms of Alzheimer\u2019s disease. Roundtable: Treating Alzheimer\u2019s disease: present potential and future prospects. University of Minnesota. Accreditation Council for Continuing Medical Education. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 20-August 3, 1994. \r\n\r\n\u00c1lvarez, X.A., Franco-Maside, A., Fern\u00e1ndez-Novoa, L., Caama\u00f1o, J., G\u00f3mez, M.J., Novo, B., Zas, R., Cacabelos, R. Blood levels of histamine, interleukin-1\uf062 and tumor necrosis factor in Alzheimer\u2019s disease. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 20-August 3, 1994. Neurobiol. Aging, 15(Suppl.1):S93 (1994). \r\n\r\nCaama\u00f1o, J., G\u00f3mez, M.J., Vinagre, D., Franco, A., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Zas, R., Novo, B., Cacabelos, R. Hemodynamic parameters of the middle cerebral artery in cerebrovascular disorders and senile dementia: A transcranial Doppler study. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 29-August 3, 1994. Neurobiol. Aging, 15 (Suppl.1):S96 (1994). \r\n\r\nFranco-Maside, A., Caama\u00f1o, J., Vinagre, D., G\u00f3mez. M.J., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Brain electrical activity mapping correlates with cerebral blood flow velocity in Alzheimer\u2019s disease. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 29-August 3, 1994. Neurobiol. Aging, 15(Suppl.1):S98 (1994).\r\n\r\nG\u00f3mez, M.J., Caama\u00f1o, J., Vinagre, D., Franco, A., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X., Zas, R., Novo, B., Cacabelos, R. Cognitive and non-cognitive profiles in cerebrovascular disorders and senile dementia: A neuropsychological study. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 29-August 3, 1994. Neurobiol. Aging, 15(Suppl.1);S106 (1994) \r\n\r\nFern\u00e1ndez-Novoa, L., Franco-Maside, A., \u00c1lvarez, X.A., Caama\u00f1o, J., G\u00f3mez, M.J., Zas, R., Cacabelos, R. Histamine, interleukin- IO and tumor necrosis factor correlate with brain electrical activity mapping in Alzheimer\u2019s disease. 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 29-August 3, 1994. Neurobiol. Aging, 15 (Suppl.l):S l21 (1994). \r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L. Brain tumor necrosis factor alpha (TNF) in Alzheimer\u2019s disease (AD). 4th Int. Conf. Alzheimer\u2019s Disease and Related Disorders. Minneapolis, July 29-August 3, 1994. Neurobiol. Aging, 15(Suppl.1):S152 (1994). \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Vinagre, D., G\u00f3mez, M.J., Sada, G., Cacabelos, R. Effects of polipodium leucotomos (Difur) on behavioral parameters and brain neuroimmune factors in nbm-lesioned rats. ECNP, Jerusalem, Oct. 16-21, 1994. \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Franco, A., Kamoun, A., Deslandes, A., Polo, E., Gorostiaga, C., Cacabelos, R. S-9977-2 normalizes behavior and brain interleukin-1\uf062 levels in rats with lesions in the nucleus basalis of Meynert. ECNP, Jerusalem, Oct. 16-21, 1994. \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Caama\u00f1o, J., Novo, B., D\u00edaz, J., Sempere, J.M., Cacabelos, R. Behavioral and neuroimmune effects of anapsos in cognitively-impaired rats. ECNP. Jerusalem, Oct. 16-21, 1994. \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Cacabelos, R. Effects of scopolamine on behavior and brain neuroimmune factors in rats. 17th Ann. Meet. Eur. Neurosci. Assoc., Vienna, 4-8 Sept., pp. 95 (1994). \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Vinagre, D., Sada, G., Cacabelos, R. Effects of polipodium leucotomos (Difur) on behavior and brain neuroimmune factors in nbM-lesioned rats. 17th Ann. Meet. Eur. Neurosci. Assoc., Vienna, 4-8 Sept., pp. 99 (1994). \r\n\r\nCaama\u00f1o, J., G\u00f3mez, M.J., Vinagre, D., Franco, A., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Zas, R., Novo, B., Cacabelos, R. Hemodynamic parameters of the middle cerebral artery in cerebrovascular disorders and senile dementia. 17th Ann. Meet. Eur. Neurosci. Assoc., Vienna, 4-8 Sept., pp. l l0 (1994). \r\n\r\nVinagre, D., Franco-Maside, A., Caama\u00f1o, J., G\u00f3mez, M.J., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Novo, B., Zas, R., Cacabelos, R. Brain electrical activity mapping in senile dementia and cerebrovascular disorders. 17th Ann. Meet. Eur. Neurosci. Assoc., Vienna, 4-8 Sept., pp. 110 (1994). \r\n\r\nCacabelos, R., Franco, A., Fern\u00e1ndez-Novoa, L., Zas, R., D\u00edaz, J., Sempere, J.M., \u00c1lvarez, X.A. Behavioral and neuroimmune effects of Anapsos in intact and nbM-lesioned rats. IBC\u2019s Third Annual Alzheimer\u2019s Disease. Advances in Understanding and treatment. Philadelphia, 22-23 Sept. (1994).\r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., Zas, R., Franco-Maside, A., Deslandes, A., Garc\u00eda, M., Kamoun, A., \u00c1lvarez, X.A. Effects of S-9977-2 on behavior and brain neuroimmune factors in rats. IBC\u2019s Third Annual Alzheimer\u2019s Disease. Advances in Understanding and Treatment. Philadelphia, 22-23 Sept. (1994). \r\n\r\nCacabelos, R., Caama\u00f1o, J., G\u00f3mez, M.J., \u00c1lvarez, X.A., Novo, B., Zas, R., Garc\u00eda, M., Polo, E., Malbezin, M., Neuman, E., Guez, D. Effects of S-I2024-2 on cognition, brain mapping and cerebrovascular parameters in Alzheimer\u2019s disease. IBC\u2019s Third Annual Alzheimer\u2019s Disease. Advances in Understanding and Treatment. Philadelphia, 22-23 Sept. (1994). \r\n\r\nCacabelos, R. Bases etiopatog\u00e9nicas de la enfermedad de Alzheimer. II Symposium Hispano- Americano. Avances en Psiquiatr\u00eda. Facultad de Medicina. Universidad de Salamanca. Salamanca, 28-30 Marzo, 1995. \r\n\r\nCacabelos, R. Enfermedad de Alzheimer. Mesa Redonda. V Congreso de la Comunidad Valenciana para M\u00e9dicos Rurales y Generalistas. Benicasim, 27-29 Abril, 1995. \r\n\r\nCacabelos, R. Enfermedad de Alzheimer. Predictores de un tratamiento etiopatog\u00e9nico. IV Reuni\u00f3n de la Soc. de Psiquiatr\u00eda de la Comunidad Valenciana. Hotel Castilla, Alicante 28-29 Abril, 1995, \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Franco, A., Zas, R., Lagares, R., Sastre, I., Beyer, K., Lao, J.I., Miguel-Hidalgo, J.J., Garc\u00eda, M., Guez, D., Cacabelos, R. Effects of S-9977-2 on learning and brain vasopressin in rats. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July, 1995. Alzheimer\u2019s Res., 1(Suppl. 1):120P (1995) \r\n\r\nMiguel-Hidalgo, J.J., Maneiro, E., Franco, A., \u00c1lvarez, X.A., Cacabelos, R. Plastic effects of 1-28 amyloid \uf062-protein fragment deposits in the hippocampus with and without CDP-choline treatment. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1(Suppl. 1) :28 (1995).\r\n\r\nBeyer, K., Lao, J.l., \u00c1lvarez, X.A., Franco, A., Cacabelos, R. Alzheimer\u2019s disease genotyping in families at risk. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1(Suppl. 1):47 (1995). \r\n\r\nFern\u00e1ndez-Novoa, L., Franco-Maside, A., \u00c1lvarez, X.A., Maneiro, E., Lagares, R., Miguel-Hidalgo, J.J., Beyer, K., Bullido, M.J., Valdivieso, F., Caama\u00f1o, J., G\u00f3mez, M.J., Vinagre, D., Cacabelos, R. APO-E genotyped patients with senile dementia: Correlations between plasma interleukin-1\uf062 and whole blood histamine. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1(Suppl. 1):50 (1995). \r\n\r\nCacabelos, R., Franco, A., Bullido, M.J., Recuero, M., Sastre, L., Zas, R., \u00c1lvarez, X.A., Lao, J.I., Beyer, K., Valdivieso, F. APO-E genotypes in Alzheimer\u2019s disease and vascular dementia. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1(Suppl. 1):50 (1995). \r\n\r\nCacabelos, R., Vigo-Pelfrey, C., Franco-Maside, A., Lao, J.l., Beyer, K., Zas, R., \u00c1lvarez, X.A. Serum \uf062-amyloid levels in demented patients with different APO-E genotypes. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1 (Suppl. 1):51 (1995).\r\n\r\n\u00c1lvarez, X.A., Zas, R., Lagares, R., Franco-Maside, A., Fern\u00e1ndez-Novoa, L., D\u00edaz, J., Cacabelos. R. Effects of the chronic administration of Anapsos on behavior in old mice. Int. Symp. Alzheimer\u2019s Res., Cambridge, UK, 4-7 July 1995. Alzheimer\u2019s Res., 1(Suppl. 1):53 (1995). \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Franco, A., Zas, R., Lagares, R., Beyer, K., Lao, J.I., Miguel- Hidalgo, J.J., Garc\u00eda, M., Guez, D., Cacabelos, R. Effects of S-9977-2 on learning and brain vasopressin levels in rats. Fourth IBRO World Congr. Neurosci., Kyoto, Japan, 9-14 July, pp. 376 (1995).\r\n\r\nMiguel-Hidalgo, J.J., Lagares, R., Franco, A., Beyer, K., Lao, J.I., \u00c1lvarez, X.A., Cacabelos, R. Detection of bilateral neuronal degeneration after multiple lesions into the rat brain. Fourth IBRO World Congr. Neurosci., Kyoto, Japan, 9-14 July, pp. 246 (1995). \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Franco, A., Zas, R., Lagares, R., Beyer, K., Lao, J.I., Miguel-Hidalgo, J.J., Garc\u00eda, M., Guez, D., Cacabelos, R. Effects of S-12024-2 on brain vasopressin levels in rats. Fourth IBRO World Congr. Neurosci., Kyoto, Japan, 9-14 July, pp. 122 (1995). \r\n\r\nCacabelos, R. Demencia. Etiopatogenia. V Congr. Castellano-Leon\u00e9s de Geriatr\u00eda y Gerontolog\u00eda. Benavente, 29-30 Sept., 1995. \r\n\r\nCacabelos, R. Senile cognitive decline: Characterization of genotypic-phenotypic correlations in Alzheimer\u2019s disease. Congr. Spanish Soc. Physiological Sciences & The Physiological Society, Salamanca, 2-5 Oct., 1995. \r\n\r\nCacabelos, R. CDP-Choline. Clinical experience. XI Conferencia Internacional. Alzheimer\u2019s Disease International. Buenos Aires, 12-15 Sept., 1995. \r\n\r\nCacabelos, R., Franco-Maside, A., Bullido, M.J., Recuero, M., Sastre, I., Zas, R., \u00c1lvarez, X.A., Lao, J.I., Beyer, K., Valdivieso, F. Age- and sex-related APO-E genotypes in Alzheimer\u2019s disease and vascular dementia. 1995 World Congress on Psychiatric Genetics. Psychiatric Genetics 5:S70 (1995). \r\n\r\nBeyer, K., Lao, J.I., \u00c1lvarez, X.A., Cacabelos, R. Rapid molecular detection of the fragile X gene trinucleotide repeat. 1995 World Congress on Psychiatric Genetics. Psychiatric Genetics 5:S85 (1995).\r\n\r\n\u00c1lvarez, X.A., Zas, R., Lagares, R., Franco-Maside, A., Fern\u00e1ndez-Novoa, L., D\u00edaz, J., Cacabelos, R. Chronic Anapsos administration improves psychomotor functioning in old mice. 7th IPA Congress, Sydney, 29 Oct.-3 Nov., 1995.\r\n\r\nMiguel-Hidalgo, J.J., Maneiro, E., \u00c1lvarez, X.A., Lagares, R., Franco, A., Fern\u00e1ndez-Novoa, L., Lao, J.I., Beyer, K., Cacabelos, R. Effects of 1-28 A\uf062P deposits in the hippocampus with and without CDP-choline treatment. 7th IPA Congress, Sydney, 29 Oct.-3 Nov., 1995. \r\n\r\nBeyer, K., Lao-Villad\u00f3niga, J.I., Zas, R., Franco-Maside, A., Lagares, R., Miguel-Hidalgo, J.J., Maneiro, E., \u00c1lvarez, X.A., Cacabelos, R. A rapid molecular characterization of Alzheimer\u2019s disease. 7th IPA Congress, Sydney, 29 Oct.-3 Nov., 1995. \r\n\r\nCacabelos, R., Franco, A., Bullido, M.J., Recuero, M., Sastres, I., Zas, R., \u00c1lvarez, X.A., Lao, J.I., Beyer, K., Valdivieso, F. APO-E genotypes in Alzheimer\u2019s disease and vascular dementia. 7th IPA Congress, Sydney, 29 Oct.-3 Nov., 1995. \r\n\r\nVigo-Pelfrey, C., \u00c1lvarez, X.A., Franco-Maside, A., Cacabelos, R. Serum \uf062-Amyloid levels in Alzheimer\u2019s disease and vascular dementia. 7th IPA Congress, Sydney, 29 Oct.-3 Nov., 1995. \r\n\r\nCacabelos, R. Pharmacological treatment of memory disorders. International Conference in Neuropsychiatry. Restoring Brain Function. A Multidisciplinary Approach. The University of Illinois, Chicago, 1-2 Dec., 1995. \r\n\r\nBeyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., Franco-Maside, A., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R. Allelic frequency of ApoE in the Spanish population. HGM\u00b496. HUGO\u2019s Human Genome Meeting, Heidelberg, March 22-24, pp. 11 (1996). \r\n\r\nLao, J.I., Beyer, K., Fern\u00e1ndez-Novoa, L., Franco-Maside, A., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R. Cytogenetic findings in Alzheimer\u2019s disease. HGM\u201996. HUGO\u2019s Human Genome Meeting, Heidelberg, 22-24 March, pp. 57 (1996). \r\n\r\nAllain, H., Guez, D., Cacabelos, R., Derouesn\u00e9, C., Jolles, J., Lenzi, G.L., Levy, R., Bruno, J., Neuman, E., Lepagnol, J. Safety and efficacy of S-12024 in patients with mild to moderate Alzheimer\u2019s disease. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 74 (1996). \r\n\r\nCacabelos, R., Lagares, R., Fern\u00e1ndez-Novoa, L., Franco-Maside, A., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A. Anapsos: New therapeutic strategies for neurodegeneration and brain aging with natural neuroimmunotrophic factors. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 83 (1996). \r\n\r\nCacabelos, R., Vinagre, D., Caama\u00f1o, J., Lao, J.I., Beyer, K., \u00c1lvarez, X.A. Brain mapping and transcranial Doppler ultrasonography in Alzheimer disease drug monitoring. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 95 (1996). \r\n\r\n\u00c1lvarez, X.A., Miguel-Hidalgo, J.J., Lagares, R., Franco, A., Fern\u00e1ndez-Novoa, L., Lao, J.I., D\u00edaz, J., Sempere, J.M., Cacabelos, R. Neuroprotective activity of anapsos in rats with hippocampal degeneration. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 130 (1996). \r\n\r\n\u00c1lvarez, X.A., Franco, A., Fern\u00e1ndez, L., Beyer, K., Garc\u00eda, M., Polo, E., Desche, P., Guez, D., Cacabelos, R. Behavioral and neurochemical effects of S12024 in rats with implants of \uf062-amyloid into the hippocampus. Fourth lnternational Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 130 (1996) \r\n\r\n\u00c1lvarez, X.A., Zas, R., Garc\u00eda, M., Polo, E., Desche, P., Guez, D., Cacabelos, R. Comparative effects of S9977-2 vs Tacrine in learning and locomotion. Fourth lnternational Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 131 (1996). \r\n\r\n\u00c1lvarez, X.A., Lagares, R., Franco, A., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., Beyer, K., Cacabelos, R. Effects of CDP-choline in rats with brain neurotoxic lesions. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 131 (1996). \r\n\r\nBeyer, K., Lao, J.I., Maneiro, E., Cacabelos, R, Alzheimer soluble factor (ASF): A potential peripheral marker for genetic Alzheimer disease. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 135 (1996). \r\n\r\nCacabelos, R., Caama\u00f1o, J., G\u00f3mez, M.J., Franco-Maside, A., Vinagre, D., Novo, B., Zas, R., \u00c1lvarez, X.A., Polo, E., Garc\u00eda, M., Neuman, E., Guez, D. S-12024-2: A double-blind randomized placebo-controlled study in patients with Alzheimer disease. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 138 (1996). \r\n\r\nFern\u00e1ndez-Novoa, L., Franco-Maside, A., \u00c1lvarez, X.A., Vecino, B., D\u00edaz, J., Sempere, J.M., Cacabelos, R. Effects of anapsos on the activity of superoxide dismutase (SOD) in an animal model of neurodegeneration. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 143 (1996). \r\n\r\nFern\u00e1ndez-Novoa, L., Vinagre, D., Franco-Maside, A., Caama\u00f1o, J., \u00c1lvarez, X.A., Cacabelos, R. Effects of famotidine on the levels of blood histamine in healthy subjects: Correlation studies with brain electrical activity mapping. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 143 (1996). \r\n\r\nLao, J.I., Beyer, K., Cacabelos, R. Senile dementia-associated FOS gene mutation in the Spanish population. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 156 (1996). \r\n\r\nManeiro, E., Lao, J.I., Beyer, K., Cacabelos, R. Microglia activation by an AD-associated 19kDa soluble factor. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 160 (1996). \r\n\r\nWinblad, B., Ravizza, L., Rossor, M., Cacabelos, R. Research priorities in Alzheimer disease treatment- An international perspective. A European response. Fourth International Nice\/Springfield Symposium on Advances in Alzheimer Therapy, Nice, April 10-14, pp. 16 (1996). \r\n\r\nBeyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R. Allelic frequency of ApoE in the Spanish population. The Lancet Conference 1996. The challenge of the dementias, Edinburgh, April 25-26, pp. 38 (1996). \r\n\r\nCacabelos, R. Variaciones endocrinol\u00f3gicas en los trastornos ps\u00edquicos del anciano. XXI Congr. Nac. Soc. Esp. Geriatr\u00eda y Gerontolog\u00eda. V Reun. Soc. Castellano-Leonesa, Salamanca, Junio 5-8, 1996.\r\n\r\nCacabelos, R. Etiopatogenia y prospecciones terap\u00e9uticas de la enfermedad de Alzheimer. Actualidad cient\u00edfica y sociosanitaria de la enfermedad de Alzheimer. Fundaci\u00f3n Ram\u00f3n Areces, Madrid, Junio 6, 1996. \r\n\r\nCacabelos, R. Funci\u00f3n neuroinmunol\u00f3gica y endocrina en trastornos neurogeri\u00e1tricos. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31: Supl. I (1996). \r\n\r\nSellers, A., Rodr\u00edguez, B., Cacabelos, R., Caama\u00f1o, J.M. Evaluaci\u00f3n psicom\u00e9trica de los trastornos del sue\u00f1o en la demencia senil. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31:Supl. l (1996). \r\n\r\nFern\u00e1ndez-Novoa, L., Corzo, L., Caama\u00f1o, J., Zas, R., G\u00f3mez, M.J., \u00c1lvarez, X.A., Cacabelos, R. Hemodin\u00e1mica cerebral y niveles de histamina en enfermedad de Alzheimer y demencia vascular. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31:Supl. l (1996). \r\n\r\nBeyer, K., Lao, J.I., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J., \u00c1lvarez, X.A., Cacabelos, R. La frecuencia al\u00e9lica del ApoE en la poblaci\u00f3n gallega. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31:Supl. I (1996). \r\n\r\nManeiro, E., Cacabelos, R. Modificaci\u00f3n de la microgl\u00eda por un factor soluble del suero de pacientes con enfermedad de Alzheimer. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31:Supl. I (1996). \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Zas, R., Lagares, R., Franco, A., Beyer, K., Maneiro, E., Cacabelos, R. Efectos de anapsos sobre funci\u00f3n cerebral en ratones viejos. Rev. Esp. Geriatr\u00eda y Gerontolog\u00eda, 31: Supl. 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Influence of the APOE genotype on serum ApoE levels from Alzheimer\u2019s disease patients in the Spanish population. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 59 (1997). \r\n\r\nPichel, V.M., Caama\u00f1o, J.M., Mouzo, R., \u00c1lvarez, X.A., P\u00e9rez, P., Laredo, M., Alcaraz, M., Lao, J.I., Beyer, K., Sellers, A., Cacabelos, R. Changes in cerebral blood flow associated with disease staging and APOE genotyping in patients with senile dementia. Oholo 41st Conference. Progress in Alzheimer\u2019s and Parkinson\u2019s diseases. Fourth International Conference. Eilat, Israel, May 18-23, pp. 62 (1997). \r\n\r\nP\u00e9rez, P., \u00c1lvarez, X.A., Laredo, M., Mouzo, R., Sellers, A., Pichel, V.M., Caama\u00f1o, J.M., Lao. J.I., Beyer, K., Novo, B., Alcaraz, M., Cacabelos, R. Brain activity mapping and APOE genotyping in senile dementia. Oholo 41st Conference. 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Psychiatry 42(1S):93S (1997). \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Perea, J.E., Daniele, D., Cacabelos, R. Citicoline antagonizes bromazepam-induced amnesia in rats. 6th World Congress Biological Psychiatry June 22-27, Nice. Biol. Psychiatry, 42(1S):95S (1997). \r\n\r\n\u00c1lvarez, X.A., Laredo, M., Corzo, L., Perea, J.E., Daniele, D., Cacabelos, R. Citicoline improves memory in elderly subjects. 6th World Congress Biological Psychiatry, June 22-27, Nice. Biol. Psychiatry 42(1 S):95S (1997). \r\n\r\nLao, J.I., Beyer, K., \u00c1lvarez, X.A., Cacabelos, R. Analysis of a polymorphic tetranucleotide repeat in the TH gene in Spanish psychiatric patients. 6th World Congress Biological Psychiatry, June 22- 27, Nice. Biol. Psychiatry 42(1S):101S (1997). \r\n\r\nSellers, A., \u00c1lvarez, X.A., Rodr\u00edguez, B., Caama\u00f1o, J.M., Laredo, M., Pichel, V.M., Alcaraz, M., Cacabelos, R. Sleep disorders in patients with senile dementia. 6th World Congress Biological Psychiatry. 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Aging, 19\/4S:S184 (1998). \r\n\r\nMouzo, R., \u00c1lvarez, X.A., Sellers, M.A., Pichel, V.M., P\u00e9rez, P., Laredo, M., Caama\u00f1o, J.M., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Lao, J.I., Beyer, K., Alcaraz, M., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Treatment with anapsos in senile dementia: A double-blind placebo-controlled study. 6th International Conference on Alzheimer\u2019s Disease and Related Disorders. Amsterdam, July 18- 23. Neurobiol. Aging, 19\/4S:S184 (1998). \r\n\r\nLombardi, V., Garc\u00eda, M., Cacabelos, R. Neuroimmunomodulation induced by cerebrolysin, a brain-derived peptide preparation, on primary microglial cell cultures. 6th International Conference on Alzheimer\u2019s Disease and Related Disorders. Amsterdam, July 18-23. Neurobiol. Aging, 19\/4S:S200 (1998). \r\n\r\nVigo-Pelfrey, C., Cacabelos, R., \u00c1lvarez, X.A., Allison, C. Neurostrol, a potent anti-inflammatory drug to treat Alzheimer\u2019s disease. 6th International Conference on Alzheimer\u2019s Disease and Related Disorders. Amsterdam, July 18-23. Neurobiol. Aging, 19\/4S:S262 (1998). \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Miguel-Hidalgo, J.J., Cacabelos, R. Beta-amyloid injections into the rat hippocampus impair learning and memory. XXlst CINP Congress, Glasgow, July 12-16, pp. 391 (1998). \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Perea, J.E., Cacabelos, R. Citicoline reverses learning impairment in rats with hippocampal neurodegeneration induced by beta-amyloid. XXlst CINP Congress, Glasgow, July 12-16, pp. 391 (1998). \r\n\r\nCacabelos, R., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A., Quack, G. Protection of memantine against A\uf062(1-40)-induced neurodegeneration in the CA1 subfield. XXIst CNIP Congress, Glasgow, July 12- 16, pp. 392 (1998). \r\n\r\nCacabelos, R., Miguel-Hidalgo, J.J., \u00c1lvarez, X.A. Beta-amyloid-induced neurodegeneration in the rat hippocampal neurons of the CA1 subfield. XXlst CNIP Congress, Glasgow, July 12-16, pp. 392 (1998). \r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Miguel-Hidalgo, J.J. Effects of hippocampal beta-amyloid injections on histamine levels, SOD, and AchE activities in the rat brain. XXlst CNIP Congress, Glasgow, July 12-16, pp. 392 (1998). \r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Perea, J.E., Daniele, D., Cacabelos, R. Citicoline antagonizes bromazepam-induced amnesia in rats. XXlst CMP Congress, Glasgow, July 12-16, pp. 396 (1998).\r\n\r\nCacabelos, R., Lombardi, V., Garc\u00eda, M., \u00c1lvarez, X.A. Neuroimmunotrophic compounds from marine organisms. XXIst CNIP Congress, Glasgow, July 12-16, pp. 433 (1998). \r\n\r\nCacabelos, R. Los centros de investigaci\u00f3n como estructura de apoyo social. II Reuni\u00f3n Latinoamericana de Asociaciones de Alzheimer y Primer Foro Iberoamericano sobre el Envejecimiento Cerebral. Oaxaca, M\u00e9xico, 17-19 Marzo, 1999.\r\n\r\nCacabelos, R. La comunicaci\u00f3n con el enfermo con demencia. Por una relaci\u00f3n m\u00e1s humana. X Jornadas de Humanizaci\u00f3n. \u201cEl Atardecer de la Mente Humana\u201d. Hermanos Hospitalarios de San Juan de Dios. Centro San Rafael, Granada, 14 Abril, 1999.\r\n\r\nMesa, M.D., Fern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Cacabelos, R. Genotype frequencies in Alzheimer\u2019s disease and vascular dementia in the Spanish population. Restauraci\u00f3n Neurol\u00f3gica \u201999. CIREN, Habana, 23-25 Feb, pp. 62 (1999).\r\n\r\nLombardi, V.R.M., Garc\u00eda, M., Perea, E., Daniele, D., Cacabelos, R. Reduction of in vitro neuronal apoptosis by citicoline treatment. Restauraci\u00f3n Neurol\u00f3gica \u201999. CIREN, Habana, 23-25 Feb., pp. 61 (1999).\r\n\r\nLombardi, V.R.M., Garc\u00eda, M., Rey, L., Cacabelos, R. Neuroimmune dysfunction in Alzheimer disease patients. Restauraci\u00f3n Neurol\u00f3gica \u201999, CIREN, Habana, 23-25 Fe., pp. 61 (1999).\r\n\r\nFern\u00e1ndez-Novoa, L., Mesa, M.D., \u00c1lvarez, X.A., Cacabelos, R. Genetic associations and risk factors in Alzheimer\u2019s disease. Restauraci\u00f3n Neurol\u00f3gica \u201999, CIREN, Habana, 23-25 Feb., pp. 60 (1999).\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Antiapoptotic effects of CDP-choline in a combined (hypoperfusion + \uf062-amyloid) animal model of hippocampal neurodegeneration. Restauraci\u00f3n Neurol\u00f3gica \u201999, CIREN, Habana, 23-25 Feb., pp. 58 (1999).\r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Sampedro, C., Lombardi, V., Cacabelos, R., Windisch, M. Neuroimmunotrophic effects of cerebrolysin in an animal model of neurodegeneration induced by \uf062-amyloid. Restauraci\u00f3n Neurol\u00f3gica \u201999, CIREN, Habana, 23-25 Feb., pp. 58-59 (1999).\r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Lombardi, V. Basic mechanisms of neuroprotection and genotype-related therapeutic response in Alzheimer\u2019s disease: Implications for active treatment and prevention in dementia. Restauraci\u00f3n Neurol\u00f3gica \u201999, CIREN, Habana, 23-25 Feb., pp. 56 (1999).\r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Sampedro, C., Lombardi, V., Cacabelos, R., Windisch, M. Cerebrolysin reverses learning impairment and brain neuroimmune activation in an animal model of neurodegeneration induced by \uf062-amyloid. Keystone Symposia on Molecular & Cellular Biology. Molecular Mechanisms in Alzheimer\u2019s Disease. Taos, New Mexico, March 3-9, pp. 48 (1999).\r\n\r\nLombardi, V.R.M., Garc\u00eda, M., Rey, L., Cacabelos, R. Peripheral immunological abnormalities and lymphocyte dysfunction in Alzheimer disease. Keystone Symposia on Molecular & Cellular Biology. Molecular Mechanisms in Alzheimer\u2019s Disease. Taos, New Mexico, March 3-9, pp. 52 (1999).\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V., Mesa, M.D., Cacabelos, R. Genetic risk factors in Alzheimer disease and vascular dementia in the Spanish population. Keystone Symposia on Molecular & Cellular Biology. Molecular Mechanisms in Alzheimer\u2019s Disease. Taos, New Mexico, March 3-9, pp. 35 (1999).\r\n\r\nCacabelos, R., Mesa, M.D., Fern\u00e1ndez-Novoa, L. Association between genotypes and risk factors in Alzheimer\u2019s disease. Keystone Symposia on Molecular & Cellular Biology. Molecular Mechanisms in Alzheimer\u2019s Disease. Taos, New Mexico, March 3-9, pp. 35 (1999).\r\n\r\nCacabelos, R. Gen\u00e9tica de la enfermedad de Alzheimer. Diagn\u00f3stico Molecular y Predictivo de Riesgo Familiar. Simposio Regional Norte-Sur APAL. Asociaci\u00f3n Psiqui\u00e1trica de America Latina. Isla Margarita, Venezuela. Nov. 23-27, pp. 54-55 (1999).\r\n\r\nCacabelos, R. Tratamiento farmacol\u00f3gico de la demencia senil. Simposio Regional Norte-Sur APAL. Asociaci\u00f3n Psiqui\u00e1trica de America Latina. Isla Margarita, Venezuela. Nov. 23-27, pp. 70-71 (1999).\r\n\r\nLaredo, M., Couceiro, V., P\u00e9rez, P., Anido, R., Figueroa, J., Garc\u00eda, E., Manti\u00f1\u00e1n, N.P., \u00c1lvarez, X.A., Cacabelos, R. Neurorehabilitaci\u00f3n en traumatismos craneoencef\u00e1licos. I Congreso Nacional de Psicolog\u00eda Cl\u00ednica y de la Salud. Orense, 23-27 Nov., pp. 140-141 (1999).\r\n\r\nLaredo, M., G\u00f3mez, E., Gallo, E., Corzo, L., Couceiro, V., Anido, R., P\u00e9rez, P., \u00c1lvarez, X.A., Cacabelos, R. Evaluaci\u00f3n de las funciones del lenguaje en la demencia senil. I Congreso Nacional de Psicolog\u00eda Cl\u00ednica y de la Salud. Orense, 23-27 Nov., pp. 114-115 (1999).\r\n\r\nCacabelos, R. Cerebrolysin enhances brain bioelectrical activity alpha and improves memory performance in humans. Internal Meeting Research Initiative EBEWE. Graz, Austria. Sept. 23 (1999).\r\n\r\nCacabelos, R., Mesa, M.D., Fern\u00e1ndez-Novoa, L. Genetic epidemiology of risk factors in Alzheimer\u2019s disease. Human Genome Meeting. Brisbane, Australia, 27-30 March, pp. 26 (1999).\r\n\r\nMesa, M.D., Fern\u00e1ndez-Novoa, L., Lombardi, V.R., \u00c1lvarez, X.A., Cacabelos, R. ADGT-Kit: A diagnostic aid for the analysis of genetic risk factors involved in the etiopathogenesis of Alzheimer\u2019s disease and vascular dementia. Human Genome Meeting. Brisbane, Australia, 27-30 March, pp. 26 (1999).\r\n\r\n\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Alcaraz, M., Sempere, J.M., D\u00edaz, J., Cacabelos, R. A double-blind placebo-controlled study with anapsos in vascular dementia and Alzheimer disease. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 23 (1999).\r\n\r\nP\u00e9rez, P., Corzo, L., \u00c1lvarez, X.A., Laredo, M., Cacabelos, R. Changes in brain bioelectrical activity associated with cognitive and behavioral function in dementia. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 27 (1999).\r\n\r\nCorzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Olano, M., Mesa, D., Cacabelos, R. Serum apolipoprotein E and lipid levels in vascular dementia and Alzheimer disease. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 30 (1999).\r\n\r\nLaredo, M., G\u00f3mez, E., Gallo, E., Corzo, L., \u00c1lvarez, X.A., Cacabelos, R. Evaluation of language functions in senile dementia. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 35 (1999).\r\n\r\nLaredo, M., P\u00e9rez, P., Couceiro, V., Anido, R., Corzo, L., \u00c1lvarez, X.A., Cacabelos, R. Sleep disorders in vascular dementia and Alzheimer disease. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 35 (1999).\r\n\r\nFern\u00e1ndez-Novoa, L., Mesa, M.D., Olano, M., Lombardi, V., \u00c1lvarez, X.A., Cacabelos, R. Evaluation of the genetic profile in Alzheimer\u2019s disease and vascular dementia. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 41 (1999).\r\n\r\nFern\u00e1ndez-Novoa, L., Mesa, M.D., de Olano, M., Lombardi, V., \u00c1lvarez, X.A., Cacabelos, R. Genotype characterization in Alzheimer disease according to gender, disease expression and age at onset. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 41 (1999).\r\n\r\nde Olano, M., Mesa, M.D., Blanco, A., Fern\u00e1ndez-Novoa, L., Corzo, L., Cacabelos, R. Angiotensin-converting enzyme I\/D polymorphism in cerebrovascular pathology. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 41 (1999).\r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Sampedro, C., Lombardi, V., Windisch, M., Cacabelos, R. Neuroimmunotrophic effects of Cerebrolysin in an animal model of hippocampal degeneration induced by \uf062-amyloid. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 43 (1999).\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. CDP-Choline reduces neuronal apoptosis in rats with brain hypoperfusion and hippocampal \uf062-amyloid implants. 1st Int. Cong. Vascular Dementia. Geneva, 3-6 Oct., pp. 43 (1999).\r\n\r\nCacabelos, R. Os inhibidores da acetilcolinesterasa como factor de esperan\u00e7a no tratamento da doen\u00e7a de Alzheimer. O Idoso no Ano 2000. Velhos sao os Trapos. Auditorio dos Hospitais da Universidade de Coimbra. Associa\u00e7ao Portuguesa de Gerontopsiquiatr\u00eda. Coimbra, 20-22 Janeiro (2000).\r\n\r\nCacabelos, R. Genetica da doen\u00e7a de Alzheimer. Workshop Universidade de Coimbra. 22 Janeiro (2000).\r\n\r\nCacabelos, R. Avances en la etiolog\u00eda de las demencias. VII Congreso Nacional. Asociaci\u00f3n Colombiana de Psiquiatr\u00eda Biol\u00f3gica. Pereira, Colombia, 18-19 Marzo (2000).\r\n\r\nCacabelos, R. Farmacogen\u00e9tica de las demencias. VII Congreso Nacional. Asociaci\u00f3n Colombiana de Psiquiatr\u00eda Biol\u00f3gica. Pereira, Colombia, 18-19 Marzo (2000).\r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V., \u00c1lvarez, X.A. Genotype-specific apoptosis and therapeutic response in Alzheimer disease: Implications for drug design and clinical trials. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 41 (2000).\r\n\r\n\u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., De Olano, M., Sampedro, C., Lombardi, V., Windisch, M., Cacabelos, R. Cerebrolysin exerts neuroimmunotrophic and neuroprotective effects in an animal model of hippocampal neurodegeneration. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 197 (2000).\r\n\r\n\u00c1lvarez, X.A., Lombardi, V.R.M., Corzo, L., P\u00e9rez, P., Pichel, V., Laredo, M., Hern\u00e1ndez, A., Freixeiro, F., Sampedro, C., Lorenzo, R., Alcaraz, M., Windisch, M., Cacabelos, R. Oral Cerebrolysin potentiates brain alpha activity and improves memory in elderly humans. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 197 (2000).\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Lozano, R., Secades, J., Cacabelos, R. Citicoline protects hippocampal neurons against apoptosis induced by brain \uf062-amyloid deposits plus cerebral hypoperfusion in rats. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 198 (2000).\r\n\r\n\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Double-blind, randomized, placebo-controlled pilot study with anapsos in senile dementia: Effects on cognition, brain electrical activity and cerebral hemodynamics. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 198 (2000).\r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Laredo, M., Couceiro, V., Anido, R., P\u00e9rez, P., Pichel, V., Corzo, L., Zas, R., Alcaraz, M., Garc\u00eda, M., Rodr\u00edguez, S., Freixeiro, F., Figueroa, J., Hern\u00e1ndez, M.A., Lombardi, V., Fern\u00e1ndez-Novoa, L. Cognitive performance in dementia patients during a 4-year follow-up with a neuroprotective multifactorial treatment: Comparative effects for prevention in subjects at risk. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 201 (2000).\r\n\r\nCacabelos, R., Moreno, A., Caama\u00f1o, J.M., L\u00f3pez, S., P\u00e9rez, P., Pichel, V., Laredo, M., Couceiro, V., Anido, R., Corzo, L., Zas, R., Alcaraz, M., Rodr\u00edguez, S., Hern\u00e1ndez, M.A., \u00c1lvarez, X.A., Lombardi, V., Fern\u00e1ndez-Novoa, L. Cognitive function and brain atrophy in dementia: A psychomorphometric correlation analysis. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 202 (2000).\r\n\r\nde Olano, M., Fern\u00e1ndez-Novoa, L., Mesa, M.D., Corzo, L., Cacabelos, R. Different allele frequency distribution in angiotensin-converting enzyme I\/D polymorphism and angiotensinogen M235T polymorphism in dementia. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 205 (2000).\r\n\r\nFern\u00e1ndez-Novoa, L., De Olano, M., Mesa, M.D., Cacabelos, R. Alpha-2 macroglobulin V1000I and insertion-deletion polymorphisms in Alzheimer\u2019s disease. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 208 (2000).\r\n\r\nFern\u00e1ndez-Novoa, L., de Olano, M., Mesa, M.D., Corzo, L., Lombardi, V., \u00c1lvarez, X.A., Cacabelos, R. Identification of two novel mutations in the amyloid precursor protein (APP) gene. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 208 (2000).\r\n\r\nLombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Sampedro, C., De Olano, M., \u00c1lvarez, X.A., Cacabelos, R. Overexpression of FAS\/CD95 in spontaneous and induced apoptosis in lymphocytes from Alzheimer\u2019s disease patients. Sixth International Stockholm\/Springfield Symposium on Advances in Alzheimer Therapy. Stockholm, April 5-8, pp. 217 (2000).\r\n\r\nCacabelos, R. Review of research in geriatric psychiatry. American Society of Hispanic Psychiatry and University of Chicago of Illinois at Chicago. Hispanic American Day at the APA Annual Meeting. May 13 (2000).\r\n\r\n\u00c1lvarez, X.A., Lombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Garc\u00eda, M., Sampedro, C., Cagiao, A., Windisch, M., Moessler, H., Cacabelos, R. Cerebrolysin reduces microglia activation in vivo and in vitro: A potential neuroprotection mechanism. Neuroinflammation in Alzheimer\u2019s Disease. A Neurobiology of Aging Conference. Washington DC, 7-8 July, pp. 2.06 (2000).\r\n\r\nLombardi, V.R.M., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Garc\u00eda, M., Sampedro, C., de Olano, M., Cacabelos, R. Regulation of brain immunity: A central role played by \uf062-amyloid and IL-1\uf062 in microglial cells. Neuroinflammation in Alzheimer\u2019s Disease. A Neurobiology of Aging Conference. Washington DC, 7-8 July, pp. 2.07 (2000).\r\n\r\nLombardi, V.R.M., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., de Olano, M., Corzo, L., Sampedro, C., Cacabelos, R. One year \u201cplateau-phase\u201d in microglial cell cultures. Neuroinflammation in Alzheimer\u2019s Disease. A Neurobiology of Aging Conference. Washington DC, 7-8 July, pp. 2.08 (2000).\r\n\r\nCacabelos, R., Sampedro, C., \u00c1lvarez, X.A. Citicoline exerts antiapoptotic effects in an animal model of hippocampal neurodegeneration. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S87 (2000).\r\n\r\nLombardi, V., Cacabelos, R., P\u00e9rez, P., Laredo, M., Moessler, H., Hern\u00e1ndez, A., Windisch, M., \u00c1lvarez, X.A. Cerebrolysin improves memory performance and the brain bioelectrical activity pattern in elderly humans. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S157 (2000).\r\n\r\n\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Dose-dependent effects of Anapsos in senile dementia patients: A double-blind, randomized, placebo-controlled study. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S218 (2000).\r\n\r\nMesa, M.D., Fern\u00e1ndez-Novoa, L., de Olano, M., Cacabelos, R. Allele frequency of alpha-2 macroglobulin V1000I and insertion-deletion polymorphism in Alzheimer\u2019s disease patients. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S250 (2000).\r\n\r\nFern\u00e1ndez-Novoa, L., Mesa, M.D., Corzo, L., de Olano, M., Cacabelos, R. Two novel mutations in the amyloid precursor protein (APP) gene. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S250 (2000).\r\n\r\nDe Olano, M., Fern\u00e1ndez-Novoa, L., Mesa, M.D., Corzo, L., Cacabelos, R. Angiotensin-converting enzyme I\/D polymorphism and ansiotensinogen M235T polymorphism in dementia: A genetic study. World Alzheimer Congress 2000. Washington DC, July 9-13, pp. S250 (2000).\r\n\r\nLombardi, V.R.M., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., de Olano, M., Perea, L., Daniele, D., Cacabelos, R. Regulation of MHC class-I and class-II expression and neuronal death by citicoline. IV European Meeting on Glial Cell Function in Health and Disease. Barcelona, 24-27 May, pp. 100 (2000).\r\n\r\nLombardi, V.R.M., \u00c1lvarez, X.A., Sampedro, C., Miguel-Hidalgo, J.J., Quack, G., Cacabelos, R. Modulation of A\uf062(1-40)-induced neurodegeneration in the CA1 subfield by memantine. IV European Meeting on Glial Cell Function in Health and Disease. Barcelona, 24-27 May, pp. 100 (2000).\r\n\r\nLombardi, V.R.M., \u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Cerebrolysin-regulated microglial function through the modulation of proinflammatory cytokines. IV European Meeting on Glial Cell Function in Health and Disease. Barcelona, 24-27 May, pp. 107 (2000).\r\n\r\n\u00c1lvarez, X.A., de Olano, M., Sampedro, C., Lombardi, V., Moessler, H., Windisch, M., Cacabelos, R. Cerebrolysin protects against neurodegeneration induced by \uf062-amyloid in rats. XXIInd CINP Congress, Brussels, 9-13 July, pp. S359 (2000).\r\n\r\n\u00c1lvarez, X.A., Lombardi, V.R.M., Corzo, L., Zas, R., P\u00e9rez, P., Pichel, V., Laredo, M., Hern\u00e1ndez, A., Freixeiro, F., Sampedro, C., Lorenzo, R., Alcaraz, M., Moessler, H., Windisch, M., Cacabelos, R. Oral Cerebrolysin accelerates the brain bioelectrical activity pattern and enhances memory performance in elderly humans. XXIInd CINP Congress, Brussels, 9-13 July, pp. S359 (2000).\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Lozano, R., Secades, J., Cacabelos, R. Citicoline protects neurons against apoptosis induced by deposits of \uf062-amyloid into the hippocampus plus cerebral hypoperfusion in rats. XXIInd CINP Congress, Brussels, 9-13 July, pp. S359 (2000).\r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Mesa, M., Olano, M., Laredo, M., Pichel, V., P\u00e9rez, P., Corzo, L., Lombardi, V. Genotype-related therapeutic response in Alzheimer\u2019s disease: A pharmacogenomic approach. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 31 (2000).\r\n\r\n\u00c1lvarez, X.A., Lombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Garc\u00eda, M., Sampedro, C., Cagiao, A., Windisch, M., Moessler, H., Cacabelos, R. Cerebrolysin reduces microglia activation in vivo and in vitro. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 177 (2000).\r\n\r\n\u00c1lvarez, X.A., Lombardi, V., Corzo, L., P\u00e9rez, P., Pichel, V., Laredo, M., Hern\u00e1ndez, A., Freixeiro, F., Sampedro, C., Lorenzo, R., Alcaraz, M., Windisch, M., Moessler, H., Cacabelos, R. Cerebrolysin improves memory and induces brain bioelectrical activation in elderly humans after a single oral administration. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 177 (2000).\r\n\r\n\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Corzo, D., Zas, R., Fern\u00e1ndez-Novoa, L., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Effects of anapsos on cognition, brain bioelectrical activity and cerebral hemodynamics in senile dementia: A double-blind, randomized, placebo-controlled study. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 125 (2000).\r\n\r\n\u00c1lvarez, X.A., Mouzo, R., Pichel, V., P\u00e9rez, P., Laredo, M., Fern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., Alcaraz, M., Secades, J.J., Lozano, R., Cacabelos, R. Effects of citicoline on cognitive performance, brain bioelectrical activity and cerebral perfusion in APOE-genotyped Alzheimer\u2019s disease patients. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 176 (2000).\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Lozano, R., Secades, J., Cacabelos, R. Neuroprotective and antiapoptotic effects of citicoline in rats with hippocampal degeneration induced by \uf062-amyloid and hypoperfusion. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 176 (2000).\r\n\r\n\u00c1lvarez, X.A., Miguel-Hidalgo, J.J., Quack, G., Cacabelos, R. Memantine protects against neuronal degeneration induced by A\uf062(1-40) in the CA1 subfield of the rat hippocampus. VII World Conference on Clinical Pharmacology and Therapeutics IUPHAR-Division of Clinical Pharmacology & 4th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). Florence, 15-20 July, 2000. British J. Clin. Pharmacol., pp. 176 (2000).\r\n\r\nFern\u00e1ndez-Novoa, L., de Olano, M., Mesa, M.D., Cacabelos, R. Alpha-2 macroglobulin polymorphism in Alzheimer\u2019s disease. Eighth World Congress of Psychiatric Genetics. Versailles, 27-31 August, pp. 522 (2000).\r\n\r\nde Olano, M., Fern\u00e1ndez-Novoa, L., Mesa, M.D., Corzo, L., Cacabelos, R. Association between ACE I\/D and APOE polymorphisms in different kinds of dementia. Eighth World Congress of Psychiatric Genetics. Versailles, 27-31 August, pp. 522 (2000).\r\n\r\nFern\u00e1ndez-Novoa, L., de Olano, M., Mesa, M.D., Corzo, L., Cacabelos, R. Identification of two novel mutations in the amyloid precursor protein (APP) gene. Eighth World Congress of Psychiatric Genetics. Versailles, 27-31 August, pp. 522 (2000).\r\n\r\nCacabelos, R., \u00c1lvarez, X.A., Fern\u00e1ndez-Novoa, L., Mesa, M.D., Olano, M., Laredo, M., Pichel, V., P\u00e9rez, P., Corzo, L., Lombardi, V. A pharmacogenomic approach to Alzheimer disease treatment. Eighth World Congress of Psychiatric Genetics. Versailles, 27-31 August, pp. 541 (2000).\r\n\r\nCacabelos, R. Hipertensi\u00f3n y demencia. VII Congreso de la Sociedad Gallega de Hipertensi\u00f3n Arterial. Sada, La Coru\u00f1a, Sept. 8-9 (2000).\r\n\r\nCorzo, L., \u00c1lvarez, X.A., Zas, R., Rodr\u00edguez, S., P\u00e9rez, P., Cacabelos, R. Niveles de tensi\u00f3n arterial, l\u00edpidos y glucosa en pacientes con demencia senil: Estudio de correlaci\u00f3n. VII Congreso de la Sociedad Gallega de Hipertensi\u00f3n Arterial. Sada, La Coru\u00f1a, Sept. 8-9, pp. 596 (2000).\r\n\r\n\u00c1lvarez, X.A., Mouzo, R., Pichel, V., Laredo, M., P\u00e9rez, P., Couceiro, V., Corzo, L., Zas, R., Varela, M., Sampedro, C., Fern\u00e1ndez-Novoa, L., Mesa, M.D., De Olano, M., Cacabelos, R. Tensi\u00f3n arterial y genotipo apolipoprote\u00edna E (APOE) en la demencia senil. VII Congreso de la Sociedad Gallega de Hipertensi\u00f3n Arterial. Sada, La Coru\u00f1a, Sept. 8-9, pp. 600 (2000).\r\n\r\nFern\u00e1ndez-Novoa, L., Corzo, L., de Olano, M., Cacabelos, R. Estudio de los polimorfismos de los genes ECA y AGT en demencia e hipertensi\u00f3n arterial. VII Congreso de la Sociedad Gallega de Hipertensi\u00f3n Arterial. Sada, La Coru\u00f1a, Sept. 8-9, pp. 600 (2000).\r\n\r\nCacabelos, R. Update in Alzheimer therapeutics. Simposio Pfizer CNS. Demencia hoje\u2026 o olhar no futuro. Funchal, Madeira, Portugal. 23 Sept. (2000).\r\n\r\nCacabelos, R. Gen\u00e9tica de la esquizofrenia y s\u00edndrome psic\u00f3tico. XVIII Congreso Venezolano de Psiquiatr\u00eda \u201cDr. Mauro Villegas\u201d. Psiquiatr\u00eda del Nuevo Milenio. Hotel Radisson Plaza Eurobuilding, Caracas, 18-21 Octubre 2000.\r\n\r\nCacabelos, R. Farmacogen\u00e9tica de la enfermedad de Alzheimer. XVIII Congreso Venezolano de Psiquiatr\u00eda \u201cDr. Mauro Villegas\u201d. Psiquiatr\u00eda del Nuevo Milenio. Hotel Radisson Plaza Eurobuilding, Caracas, 18-21 Octubre 2000.\r\n\r\nCacabelos, R. Gen\u00f3mica: Repercusiones diagn\u00f3sticas y terap\u00e9uticas. Simposio Internacional. Hacia una Sociedad Gerontol\u00f3gico. Universidad de Oviedo y Fundaci\u00f3n Ram\u00f3n Areces, Oviedo, 21-22 Noviembre, 2000.\r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Lombardi, V. Distribution of polygenic genotypes in Alzheimer disease (AD): Genomic screening of AD-associated genes. Eur. Neuropsychopharmacol., 11(Suppl.1):S15 (2001).\r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Lombardi, V. Pharmacogenomic studies in Alzheimer disease with a multifactorial treatment. Eur. Neuropsychopharmacol., 11(Suppl.1):S15 (2001).\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V., P\u00e9rez-Herrera, S., Cacabelos, R. Angiotensin-converting enzyme I\/D polymorphism in polygenic disorders. Eur. Neuropsychopharmacol., 11(Suppl.1):S16 (2001).\r\n\r\nIzasa, C., Henao, J., L\u00f3pez, A.M., Cacabelos, R. CYP2D6 allelic variants in the Colombian population. Eur. Neuropsychopharmacol., 11(Suppl.1):S16 (2001).\r\n\r\nCacabelos, R. Innovaci\u00f3n biotecnol\u00f3xica e iniciativa empresarial. GALIEMPREGO 2001. III Feira da Formaci\u00f3n e o Emprego. Xunta de Galicia, Santiago de Compostela, 15-17 Mayo, 2001.\r\n\r\nCacabelos, R. Immune function, cytokines and apoptosis in Alzheimer disease: Implications for drug monitoring and pharmacogenomics. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; A-5-4, pp. 13 (2001).\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V., \u00c1lvarez, X.A., Corzo, L., P\u00e9rez-Herrera, S., Sampedro, C., Zas, R., Cacabelos, R. Alpha 2-macroglobulin polymorphisms in early- and late-onset Alzheimer\u2019s disease. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-15, pp. 39 (2001).\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V., \u00c1lvarez, X.A., Corzo, L., P\u00e9rez-Herrera, S., Sampedro, C., Zas, C., Cacabelos, R. Angiotensin-converting enzyme I\/D polymorphism in multifactorial human diseases. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-16, pp. 39 (2001).\r\n\r\nLaredo, M., Couceiro, V., P\u00e9rez, P., \u00c1lvarez, X.A., Cacabelos, R. Senile Dementia-Associated Sleep Disorders Scale (SDASDS). New data on the validation of the Sleep-Related Subscale. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-31, pp. 43 (2001).\r\n\r\nP\u00e9rez, P., Laredo, M., \u00c1lvarez, X.A., Cacabelos, R. Fronto-temporal brain bioelectrical activity theta correlates with hallucinations in Alzheimer disease. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-32, pp. 43 (2001).\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Lozano, R., Secades, J., Cacabelos, R. Citicoline reduces neuronal degeneration and apoptosis induced by \uf062-amyloid and hypoperfusion in rats. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-51, pp. 48 (2001).\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Lombardi, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R., Moessler, H., Windisch, M. Procognitive, immunomodulatory and neurotrophic activities of Cerebrolysin in an animal model of hippocampal degeneration. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; III-AD-55, pp. 49 (2001).\r\n\r\nCorzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Lombardi, V., Cacabelos, R. Vitamin B12 and folate deficiency in dementia. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-06, pp. 93 (2001).\r\n\r\nCorzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Lombardi, V., Cacabelos, R. Thyroid function study in dementia. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-07, pp. 93 (2001).\r\n\r\n\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Fern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., Alcaraz, M., Sampedro, C., Cacabelos, R., Secades, J., Lozano, R. Citicoline improves cognitive performance, brain bioelectrical activity and cerebral perfusion in APOE-genotyped Alzheimer disease patients. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-26, pp. 98 (2001).\r\n\r\n\u00c1lvarez, X.A., Lombardi, V., Corzo, L., P\u00e9rez, P., Pichel, V., Laredo, M., Hern\u00e1ndez, A., Freixeiro, F., Varela, M., Sampedro, C., Alcaraz, M., Rodr\u00edguez, S., Cacabelos, R., Windisch, M., Moessler, H. Oral Cerebrolysin in elderly humans: Effects on memory and brain bioelctrical activity. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-27, pp. 98 (2001).\r\n\r\n\u00c1lvarez, X.A., Pichel, V., P\u00e9rez, P., Laredo, M., Corzo, D., Sampedro, C., Zas, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R., Sempere, J.M., D\u00edaz, J. Procognitive and neurobiological effects of anapsos in senile dementia: A double-blind and placebo-controlled study. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-28, pp. 98 (2001).\r\n\r\nLombardi, V.R.M., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Corzo, L., Zas, R., Cacabelos, R. Peripheral immune dysfunction in Alzheimer disease. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-37, pp. 100 (2001).\r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Corzo, L., Laredo, M., P\u00e9rez, P., Pichel, V., Lombardi, V. Multifactorial treatment and pharmacogenomics in Alzheimer disease. The 5th International Conference on Progress in Alzheimer\u2019s and Parkinson\u2019s disease. Kyoto, March 31-April 5, 2001; V-AD-46, pp. 103 (2001).\r\n\r\nCacabelos, R. Psychogeriatric research: Strategies and development. 16th Jap. Congr. Psychogeriatrics. Osaka, 13-15 June, 2001.\r\n\r\nCacabelos, R. Prospective treatments in Alzheimer disease. 16th Jap. Congr. Psychogeriatrics. Osaka, 13-15 June, 2001.\r\n\r\nCacabelos, R. Family, work and health. First CEDE International Congress of Directors. Enterpreneurs with values: Directors and the new Europe-America partnership. Madrid Nov. 29-30 (2002).\r\n\r\nCacabelos, R. Genomics: Implications for diagnosis and treatment. Aging at XXI century. Thinking the future. Coimbra University Hospitals, Coimbra, 21-23 March, 2002.\r\n\r\nCacabelos, R. Workshop \u201cMild Cognitive Impairment: Concept and Realities\u201d. Divonne-les-Bains, France, April 1-2, 2002.\r\n\r\nCacabelos, R. Pharmacogenomics and treatment of Alzheimer disease. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 39, 2002.\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Antiapoptotic and neuroprotective effects of anapsos in rats with beta-amyloid injections into the hippocampus. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 161, 2002.\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., P\u00e9rez, P., Pichel, V., Hern\u00e1ndez, A., Varela, M., Figueroa, J., Laredo, M., Couceiro, V., Corzo, L., Moessler, H., Cacabelos, R. Positive effects of cerebrolysin on brain bioelectrical activity and cognitive performance in traumatic brain injury and in senile dementia patients. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 162, 2002.\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Fondevila, M., Seoane, S., Cacabelos, R. Prion protein gene (PRNP) polymorphisms in Alzheimer disease. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 183, 2002.\r\n\r\nLombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Cacabelos, R. Cytokine production by human peripheral blood mononuclear cells in Alzheimer disease. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 212, 2002.\r\n\r\nPichel, V., P\u00e9rez, P., Fern\u00e1ndez-Novoa, L., Laredo, M., Couceiro, V., Alcaraz, M., Rodr\u00edguez, S., Mulet, E., Cacabelos, R. Cerebrovascular risk factors and hemodynamics in dementia. 7th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. Geneva, April 3-6, pp. 228, 2002.\r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, P., Laredo, M., Couceiro, V., Pichel, V., \u00c1lvarez, A. Alzheimer Disease-Associated Genes: Genomic Screening in the Spanish Population. Proceedings ELSO 2002, Nice, France, June 29-July 3, pp. 20 (2002).\r\n\r\nLombardi, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Evaluation of TNF-alpha and IL-10 levels in peripheral blood mononuclear cells of Alzheimer patients measured by a cytometric bead array system. Proceedings ELSO 2002, Nice, France, June 29-July 3, pp. 281 (2002).\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V., Cacabelos, R. Association studies of polymorphisms in the angiotensin converting enzyme gene (ACE) and Alzheimer\u2019s disease (AD) in the Spanish population. Proceedings ELSO 2002, Nice, France, June 29-July 3, pp. 294 (2002).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Fern\u00e1ndez-Novoa, L., Lombardi, V., Cacabelos, R. Amyloid beta-induced neurodegeneration in vivo: An experimental model to test potential anti-dementia drugs. Proceedings ELSO 2002, Nice, France, June 29-July 3, pp. 308 (2002).\r\n\r\n\u00c1lvarez, A., Cacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V. Pharmacogenomics and treatment of Alzheimer\u2019s disease. XXIIIrd CINP Congress, June 23-27, Montr\u00e9al, Canada, P.1.W.071. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S90 (2002).\r\n\r\n\u00c1lvarez, A., Fern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Fondevila, M., Seoane, S., Cacabelos, R. M129V polymorphism at the PRNP gene and Alzheimer\u2019s disease in the Spanish population. XXIIIrd CINP Congress, June 23-27, Montr\u00e9al, Canada, P.2.E.098. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S118 (2002).\r\n\r\n\u00c1lvarez, A., Cacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V., P\u00e9rez, P., Laredo, M., Couceiro, V., Alcaraz, M., Rodr\u00edguez, S., Sampedro, C., Pichel, V. Genomic screening of Alzheimer\u2019s disease-associated genes in the Spanish population. XXIIIrd CINP Congress, June 23-27, Montr\u00e9al, Canada, P.2.E.095. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S117 (2002).\r\n\r\n\u00c1lvarez, A., Cacabelos, R., Pichel, V., P\u00e9rez, P., Fern\u00e1ndez-Novoa, L., Laredo, M., Couceiro, V., Alcaraz, M., Rodr\u00edguez, S., Mulet, E., Sampedro, C., Lombardi, V. Cerebrovascular risk factors and hemodynamics in dementia. XXIIIrd CINP Congress, June 23-27, Montr\u00e9al, Canada, P.1.W.067. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S89 (2002).\r\n\r\n\u00c1lvarez, A., Sampedro, C., P\u00e9rez, P., Pichel, V., Hern\u00e1ndez, A., Varela, M., Figueroa, J., Laredo, M., Couceiro, V., Corzo, L., Moessler, H., Cacabelos, R. Cerebrolysin improves brain bioelectrical activity pattern and cognitive functioning in traumatic brain injury and in senile dementia. XXIIIrd CINP Congress, June 23-27, Montreal, Canada, P.1.W.081. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S92 (2002).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Central beta-amyloid impairs learning and induces neuronal degeneration and apoptosis in rats: Neuroprotective effects of Anapsos. XXIIIrd CINP Congress, June 23-27, Montreal, Canada, P.3.W.084. Intern. J. Neuropsychopharmacol., 5(Suppl.1):S177 (2002).\r\n\r\nCacabelos, R. Avances en biolog\u00eda molecular, gen\u00e9tica y neuroqu\u00edmica de la esquizofrenia. II International Congress ARAPDIS & IX Congress Mediterranean Social Psychiatrie (MESPA), Barcelona, May 26-30 (2002).\r\n\r\nCacabelos, R., Artigas, F., Fa\u00f1anas, L., Bulbena, A., Taboada, A. Bases etiopatog\u00e9nicas de la esquizofrenia: Gen\u00e9tica, biolog\u00eda molecular, neuroqu\u00edmica y neurofarmacolog\u00eda. II International Congress ARAPDIS & IX Congress Mediterranean Social Psychiatrie (MESPA), Barcelona, May 26-30 (2002).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Sempere, J.M., D\u00edaz, J., Cacabelos, R. Anapsos reverses the neurotoxic effects of central beta-amyloid injections in rats: Behavioral and morphological evaluations. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S97 (2002).\r\n\r\nMiguel-Hidalgo, J.J., \u00c1lvarez, X.A., Cacabelos, R., Quack, G. Memantine prevents beta-amyloid-induced neurotoxicity and learning impairment in rats. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S102 (2002).\r\n\r\nCacabelos, R., \u00c1lvarez, A., P\u00e9rez, P., Laredo, M., Couceiro, V., Alcaraz, M., Rodr\u00edguez, S., Pichel, V. Multifactorial therapy in vascular dementia and Alzheimer disease. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S121 (2002).\r\n\r\nLombardi, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Increased TNF-alpha and IL-10 production by human peripheral blood mononuclear cells in Alzheimer\u2019s disease measured by a cytometric bead array system. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S229 (2002).\r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V., P\u00e9rez, P., Laredo, M., Couceiro, V., Alcaraz, M., Rodr\u00edguez, S., Pichel, V., \u00c1lvarez, A. Genomic screening of Alzheimer\u2019s disease-associated genes in the Spanish population. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S318 (2002).\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V., Seoane, S., Cacabelos, R. M129V polymorphism at the PRNP gene in Alzheimer\u2019s disease. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S320 (2002).\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V., Seoane, S., Cacabelos, R. Angiotensin converting enzyme gene polymorphism (ACE) and Alzheimer\u2019s disease (AD) in the Spanish population. The 8th International Conference on Alzheimer\u2019s Disease and Related Disorders, Stockholm, Sweden, July 20-25, 2002. Neurobiol. Aging, 23(Suppl.1):S346 (2002).\r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V., Takeda, M. Genomic variation and pharmacogenomic studies in Alzheimer disease. XII World Congress of Psychiatry. Yokohama, August 24-29, pp. 111 (2002).\r\n\r\nTakeda, M., Cacabelos, R., Ray, O., Forstl, H., Hoon Oh, B. International situation of diagnosing dementia and the direction of future study. Cognition and Dementia. Round Table Discussion. Yokohama, August 27 (2002).\r\n\r\nCacabelos, R. Genomic screening, genetic variation and pharmacogenomics in Alzheimer disease. International Symposium \u201cMolecular Neurobiology of Alzheimer Disease and Related Disorders\u201d. Osaka Sun Palace Hotel, Osaka, October 5; Dementia Japan 16:83 (2002).\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V., Seoane, S., Cacabelos, R. Distribution of APOE genotypes in CNS disorders in the Spanish population. Am. J. Med. Genet., 114\/7:789 (2002).\r\n\r\nCacabelos, R., Lombardi, V., Fern\u00e1ndez-Novoa, L. Genomic variation in Alzheimer disease. Am. J. Med. Genet., 114\/7:829 (2002).\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Fondevila, M., Seoane, S., Cacabelos, R. Association study of M129V polymorphism at the PRNP gene in Alzheimer disease. Am. J. Med. Genet., 114\/7:829-830 (2002).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Cacabelos, R. Effects of central beta-amyloid on learning, glial activation, neuronal degeneration and apoptosis in rats. 6th Congress of the European Federation of Neurological Societies. Vienna, October 26-29, 2002. Eur. J. Neurol., 9(Suppl.2):158-159 (2002).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Corzo, L., P\u00e9rez, P., Pichel, V., Laredo, M., Hern\u00e1ndez, A., Varela, M., Figueroa, J., Cacabelos, R., Windisch, M., Moessler, H. . 6th Congress of the European Federation of Neurological Societies. Vienna, October 26-29, 2002. Eur. J. Neurol., 9(Suppl.2):198 (2002).\r\n\r\nCacabelos, R. Foro de nuevas bioempresas. EBIOTEC. BioSpain\/Asebio-2003. Madrid, 23-28 Feb. (2003).\r\n\r\nCacabelos, R. Genetic variation and pharmacogenomic profiles in Alzheimer disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 3.\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Central amyloid-beta impairs learning and induces glial activation, neuronal loss and apoptosis in rats. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 16.\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R., Windisch, M. AF64A-induced neuronal apoptosis in the septohippocampal area. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 17.\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R., Sempere, J.M., D\u00edaz, J. Anapsos reverses beta-amyloid-induced learning impairment, neuronal loss and apoptosis. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 17.\r\n\r\nAmado, L., Etcheverr\u00eda, I., Pichel, V., Moreno, A., Cacabelos, R. Age-dependent changes in brain atrophy parameters. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 17.\r\n\r\nAmado, L., Etcheverr\u00eda, I., Pichel, V., Moreno, A., Corzo, L., Zas, R., Lombardi, V., Cacabelos, R. Influence of vascular risk factors on brain atrophy. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 17.\r\n\r\nLombardi, V.R.M., D\u00edaz, J., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Blanco, A., Cacabelos, R. Regulation of MHC class-I and class-II expression on primary microglial cells by natural compounds. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 28.\r\n\r\nPichel, V., Amado, L., Etcheverr\u00eda, I., Cacabelos, R. Age-dependent cerebrovascular hemodynamic changes. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 33.\r\n\r\nPichel, V., Amado, L., Etcheverr\u00eda, I., Corzo, L., Zas, R., Alcaraz, M., Mulet, E., Rodr\u00edguez, S., Cacabelos, R. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 33.\r\n\r\nPichel, V., Figueroa, J., Cornes, J.M., \u00c1lvarez, X.A., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Amado, L., Hern\u00e1ndez, A., Varela, M., Cacabelos, R. Cervico-arthrosis is associated with occipital EEG slowing and a poor brain perfusion in women. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 34.\r\n\r\nAguilar-Aldrete, M.E., Cacabelos, R., Rosales-G\u00f3mez, R.C., Rodr\u00edguez-Vera, M.C., Silva-Lepe, Y., Moran-Moguel, M.C. The apolipoprotein E genotype in western Mexican population with Alzheimer disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 54.\r\n\r\n\u00c1lvarez, X.A., Lombardi, V., Sampedro, C., Corzo, L., Zas, R., P\u00e9rez, P., Laredo, M., Cruceiro, V., Astoreka, I., Varela, M., Fern\u00e1ndez-Novoa, L., Cacabelos, R., Stoeffler, A., Moebius, H.J. Genotype-related reduction of apoptosis in Alzheimer\u2019s disease patients treated with memantine. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 54.\r\n\r\nIsaza, C., Henao, J., Fern\u00e1ndez-Novoa, L., Cacabelos, R. The drug metabolizer CYP2D6 gene in Alzheimer disease therapy. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 56.\r\n\r\nEtcheverr\u00eda, I., Pichel, V., Amado, L., Fern\u00e1ndez-Novoa, L., Lombardi, V., Cacabelos, R. APOE genotype-related brain atrophy in the Spanish population. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 57.\r\n\r\nEtcheverr\u00eda, I., Pichel, V., Amado, L., Fern\u00e1ndez-Novoa, L., Alcaraz, M., Mulet, E., Rodr\u00edguez, S., Cacabelos, R. APOE-related cerebrovascular hemodynamics in the Spanish population. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 57.\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Corzo, L., Laredo, M., Cruceiro, V., \u00c1lvarez, X.A., Cacabelos, R. Association study between DCPI genotype and Alzheimer\u2019s disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 58.\r\n\r\nKubota, Y., Pichel, V., Fern\u00e1ndez-Novoa, L., Lombardi, V., \u00c1lvarez, A., Mollet, E., Alcaraz, M., Rodr\u00edguez, S., Laredo, M., Cruceiro, V., Amado, L., Etcheverr\u00eda, I., Cacabelos, R. Combination therapy in Alzheimer disease: A pharmacogenomic study. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 64.\r\n\r\nLaredo, M., Couceiro, V., Fraile, C., \u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Neuropsychological evaluation of mild degenerative dementia patients: improving the screening capacity of the MMSE. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 65.\r\n\r\nPichel, V., Etcheverr\u00eda, I., Amado, L., Cacabelos, R. Effect of cerebrovascular risk factors on brain hemodynamics in dementia. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 73.\r\n\r\nLombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Cacabelos, R. Regulating factors for pathological activation of microglia in Alzheimer\u2019s disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 121.\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Corzo, L., Zas, R., P\u00e9rez, P., Pichel, V., Laredo, M., Cruceiro, V., Hern\u00e1ndez, A., Varela, M., Figueroa, J., Lombardi, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R., Moessler, H. Cerebrolysin improves cognition and brain bioelectrical activity in senile dementia and in traumatic brain injury patients. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 126.\r\n\r\nCacabelos, R., Kubota, Y., Pichel, V., Lombardi, V., Mollet, E., Alcaraz, M., Rodr\u00edguez, S., Amado, L., Corzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Su\u00e1rez, J., Pardo, R. E-SAR-94010: A novel pleiotropic compound with age-dependent regulatory activity on lipid metabolism. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 127.\r\n\r\nCorzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. FERUM nitric oxide study in Alzheimer disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 128.\r\n\r\nCorzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., \u00c1lvarez, X.A., Laredo, M., Cruceiro, V., Sampedro, C., Rodr\u00edguez, S., Cacabelos, R. Study of serum apolipoprotein E in Alzheimer disease. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 128.\r\n\r\nFern\u00e1ndez-Novoa, L., Corzo, L., Seoane, S., Zas, R., Sampedro, C., \u00c1lvarez, X.A., Lombardi, V.R.M., Cacabelos, R. ACE serum activity and I\/D genetic polymorphism in elderly subjects. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 129.\r\n\r\nLombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Cacabelos, R. Flow cytometry analysis of supressor cell precursor and memory T lymphocytes in the peripheral blood of Alzheimer\u2019s disease patients. 6th International Conference on Alzheimer\u2019s and Parkinson\u2019s Diseases (AD\/PD-2003), Seville, May 8-12, 2003; pp. 131.\r\n\r\nTakeda, M., Cacabelos, R. (Co-chairmen), Yamada, T., Maelick, A., Kurz, A. Roundtable Discussion Meeting on Treatment for Patients with Dementia. Sal\u00f3n Lebrija. Hotel Meli\u00e1 Sevilla, May 12, 2003.\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Laredo, M., Cruceiro, V., Fern\u00e1ndez-Novoa, L., Kubota, Y., Cacabelos, R., Vargas, M. Differential influence of neuropsychiatric symptoms on functional and cognitive decline in mild-moderate Alzheimer\u2019s disease. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 41. \r\n\r\nIsaza, C., Henao, J., Fern\u00e1ndez-Novoa, L., Kubota, Y., Cacabelos, R. The drug metabolizer CYP2D6 in Alzheimer\u2019s disease. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 42.\r\n\r\nLombardi, V., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Kubota, Y., Cacabelos, R. Peripheral blood analysis of CD28-\/CD8+ supressor cell precursor and CD45RO+\/CD4+ memory T-lymphocytes in patients with Alzheimer\u2019s disease. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 42. \r\n\r\nFern\u00e1ndez-Novoa, L., Corzo, L., Seoane, S., Lombardi, V., Kubota, Y., Cacabelos, R. ACE serum activity and ACE genetic polymorphisms in elderly subjects. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 42.\r\n\r\nAmado, L., Etcheverr\u00eda, I., Pichel, V., Kubota, Y., Cacabelos, R. Age-dependent brain atrophy in CNS disorders: A CT-Scan study. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 42-43. \r\n\r\nEtcheverr\u00eda, I., Pichel, V., Amado, L., Fern\u00e1ndez-Novoa, L., Kubota, Y., Cacabelos, R. Differential brain atrophy profile associated with APOE genotype in CNS disorders. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 43.\r\n\r\nPichel, V., Amado, L., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Kubota, Y., Cacabelos, R. APOE-related cerebrovascular risk factors and hemodynamics in CNS disorders. World Psychiatric Association. International Thematic Conference. Diagnosis in Psychiatry: Integrating the sciences. Vienna, 19-22 June, 2003; pp. 43. \r\n\r\nEtcheverr\u00eda, I., Amado, L., Pichel, V., Cacabelos, R. Age- and APOE-dependent cerebrovascular changes in the Spanish population. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 32.\r\n\r\nPichel, V., Amado, L., Etcheverr\u00eda, I., Cacabelos, R. Age-dependent changes in brain hemodynamic parameters. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 38.\r\n\r\nEtcheverr\u00eda, I., Amado, L., Pichel, V., Cacabelos, R. Age-dependent brain atrophy: A CT-Scan study. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 47.\r\n\r\nEtcheverr\u00eda, I., Amado, L., Pichel, V., Cacabelos, R. Differential brain atrophy profile associated with the APOE genotype in the Spanish population. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 47.\r\n\r\nPichel, V., Amado, L., Etcheverr\u00eda, I., Cacabelos, R. Vascular risk factors and brain atrophy: A correlation analysis in the Spanish population. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 55.\r\n\r\nPichel, V., Amado, L., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Laredo, M., Cruceiro, V., Alcaraz, M., Rodr\u00edguez, S., Mulet, E., Cacabelos, R. APOE-related cerebrovascular risk factors and hemodynamics in dementia. 6th International Conference on Stroke and 3rd Conference on the Mediterranean Stroke Society. Monte Carlo, March 12-15, 2003; pp. 55.\r\n\r\nAmado, L., Etcheverr\u00eda, I., Pichel, V., Fern\u00e1ndez-Novoa, L., Lombardi, V.R.M., Cacabelos, R. APOE genotype-related brain atrophy in the Spanish population. First Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2003). G\u00f6teborg, 2003; pp. 33.\r\n\r\nEtcheverr\u00eda, I., Pichel, V., Amado, L., Fern\u00e1ndez-Novoa, L., Alcaraz, M., Mulet, E., Rodr\u00edguez, S., Cacabelos, R. APOE-related cerebrovascular hemodynamics in the Spanish population. First Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2003). G\u00f6teborg, 2003; pp. 55.\r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Tellado, I., Kubota, Y., Lombardi, V., Pichel, V.M. APOE-related phenotypic variation in brain bioelectrical activity mapping. First Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2003). G\u00f6teborg, 2003; pp. 58-59.\r\n\r\nPichel, V., Amado, L., Etcheverr\u00eda, I., Corzo, L., Zas, R., Alcaraz, M., Mulet, E., Rodr\u00edguez, S., Cacabelos, R. Vascular risk factor-associated brain hemodynamics. First Congress of the International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG 2003). G\u00f6teborg, 2003; pp. 60-61.\r\n\r\nCacabelos, R. Potential role of histamine and cytokine networks in Alzheimer disease and neurodegeneration. 1st International Symposium of Neurobehavioral Pharmacology. Okayama, September 13-15, 2003; pp. 72.\r\n\r\nLombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Chronic activation of immune\/inflammatory cells in Alzheimer\u2019s disease. VI European Meeting on Glial Cell Function in Health and Disease. Berlin, September 3-6, 2003; P-104.\r\n\r\n\u00c1lvarez, X.A., Laredo, M., Cruceiro, V., Fern\u00e1ndez-Novoa, L., Sampedro, C., Cacabelos, R., Vargas, M., Aleixandre, M. Neuropsychiatric symptoms in APOE-genotyped Alzheimer\u2019s disease patients: Contributions to diagnosis and prognosis of the disease. 16th Congress of the European College of Neuropsychopharmacology. Prague, September 20-24, 2003. European Neuropsychopharmacology, 13(Suppl.4):S399-S400 (2003). \r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Laredo, M., Cruceiro, V., P\u00e9rez, P., Cacabelos, R., Moessler, H., Doppler, E. Effects of cerebrolysin on quantitative EEG activity in elderly controls and in patients with brain damage. 16th Congress of the European College of Neuropsychopharmacology. Prague, September 20-24, 2003. European Neuropsychopharmacology, 13(Suppl.4):S400 (2003). \r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Memory deficits and neuropathology induced by central amyloid-beta injections in rats. 16th Congress of the European College of Neuropsychopharmacology. Prague, September 20-24, 2003. European Neuropsychopharmacology, 13(Suppl.4):S405 (2003). \r\n\r\n\u00c1lvarez, X.A., Lombardi, V., Fern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Cacabelos, R. CD28-\/CD8+ supressor cell precursor and CD45RO+\/CD4+ memory T lymphocyte expressions in the peripheral blood of Alzheimer\u2019s disease patients. 16th Congress of the European College of Neuropsychopharmacology. Prague, September 20-24, 2003. European Neuropsychopharmacology, 13(Suppl.4):S406 (2003). \r\n\r\nPichel, V., Etcheverr\u00eda, I., Amado, L., Kubota, Y., Cacabelos, R. Phenotypic profiles of vascular dementia and Alzheimer disease associated with brain atrophy and cerebrovascular hemodynamics. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 38.\r\n\r\nCorzo, L., Zas, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Oxidative and vascular blood markers in dementia. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 43.\r\n\r\nEtcheverr\u00eda, I., Pichel, V., Amado, L., Moreno, A., Cacabelos, R. Brain atrophy-associated vascular risk factors. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 47.\r\n\r\nEtcheverr\u00eda, I., Pichel, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Association between different APOE genotypes and cerebrovascular parameters assessed by transcranial Doppler ultrasonography in the Spanish population. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 47.\r\n\r\nPichel, V., Etcheverr\u00eda, I., Corzo, L., Zas, R., Cacabelos, R. Effects of vascular risk factors on brain hemodynamic parameters. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 51.\r\n\r\nPichel, V., Etcheverr\u00eda, I., Cacabelos, R. Age-related cerebrovascular changes in hemodynamic parameters. 3rd International Congress on Vascular Dementia. Prague, October 23-26, 2003; pp. 51.\r\n\r\nEtcheverr\u00eda, I., Vallejo, A.I., Lombardi, V.R.M., Corzo, L., Zas, R., Cacabelos, R. Efecto de BioKin sobre par\u00e1metros bioqu\u00edmicos en sangre de ratas con suplementaci\u00f3n diet\u00e9tica. IX Congreso de la Sociedad Espa\u00f1ola de Nutrici\u00f3n. Tenerife, Noviembre 26-29, 2003. Nutrici\u00f3n Hospitalaria, XVIII\/5:296 (2003). \r\n\r\nVallejo, A.I., Etcheverr\u00eda, I., Lombardi, V.R.M., Cacabelos, R. Efecto de BioKin sobre el crecimiento en ratas. IX Congreso de la Sociedad Espa\u00f1ola de Nutrici\u00f3n. Tenerife, Noviembre 26-29, 2003. Nutrici\u00f3n Hospitalaria, XVIII\/5:297 (2003). \r\n\r\nVallejo, A.I., Lombardi, V., Fern\u00e1ndez-Novoa, L., Pichel, V., Amado, L., Cacabelos, R. E-SAR-94010 (LipoEsar): Un compuesto lipoproteico pleiotr\u00f3pico con un poderoso efecto anti-ateromatoso e hipolipemiante. IX Congreso de la Sociedad Espa\u00f1ola de Nutrici\u00f3n. Tenerife, Noviembre 26-29, 2003. Nutrici\u00f3n Hospitalaria, XVIII\/5:318 (2003). \r\n\r\nEtcheverr\u00eda, I., Vallejo, A.I., Lombardi, V., Corzo, L., Zas, R., Cacabelos, R. BioKin effects on the blood biochemical parameters of rats with a supplemented diet. Nutrition, 19:1052-1053 (2003).\r\n\r\nVallejo, A.I., Lombardi, V., Fern\u00e1ndez-Novoa, L., Pichel, V., Amado, L., Cacabelos, R. E-SAR-94010 (LipoEsar): A pleiotropic lipoprotein compound with powerful anti-atheromatous and lipid-lowering effects. Nutrition, 19:1066 (2003).\r\n\r\nCacabelos, R., Lombardi, V., Kubota, Y., Pichel, V., Fern\u00e1ndez-Novoa, L. Increased genetic variation in Alzheimer disease (AD) and no apparent influence of the prion M129V polymorphism on AD pharmacogenomics. Human Genome Meeting (HGM-2004). Berlin, April 4-7, 2004; pp. 63.\r\n\r\nFern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., Seoane, S., Cacabelos, R. Influence of ACE indel polymorphism on ACE activity and plasma beta-amyloid in dementia. Human Genome Meeting (HGM-2004). Berlin, April 4-7, 2004; pp. 65.\r\n\r\nIsaza, C., Henao, J., Fern\u00e1ndez-Novoa, L., Cacabelos, R. The drug metabolizer CYP2D6 gene in Alzheimer disease. Human Genome Meeting (HGM-2004). Berlin, April 4-7, 2004; pp. 67.\r\n\r\nLombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Probable Alzheimer disease and alpha-2-macroglobulin polymorphism. Human Genome Meeting (HGM-2004). Berlin, April 4-7, 2004; pp. 70.\r\n\r\nTellado, I., Fern\u00e1ndez-Novoa, L., Lombardi, V., Pichel, V., Cacabelos, R. APOE-related phenotypic variation in brain function. Human Genome Meeting (HGM-2004). Berlin, April 4-7, 2004; pp. 75.\r\n \r\nCacabelos, R. Genetic variation, functional genomics and pharmacogenomics in Alzheimer disease. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004. Neurobiol. Aging, 25:S4 (2004).\r\n\r\n\u00c1lvarez, A., Corzo, L., Sampedro, C., Cacabelos, R. FERUM insulin-like growth factor I (IGF-I), growth hormone (GH), tumor necrosis factor-alpha (TNF) and interleukin-6 (IL6) in Alzheimer disease (AD) and mild cognitive impairment (MCI) patients. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 36.\r\n\r\n\u00c1lvarez, A., Laredo, M., Sampedro, C., Cacabelos, R. Vargas, M., Illescas, I. Prevalence of neuropsychiatric symptoms (NPS) in a clinical population of APOE-genotyped patients: Alzheimer disease (AD) versus mild cognitive impairment. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 37.\r\n\r\n\u00c1lvarez, A., Varela, M., Sampedro, C., Cruceiro, V., Cacabelos, R., Moessler, H. Positive effects of cerebrolysin in Alzheimer disease (AD): a randomized, double-blind, placebo-controlled trial (RCT). 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 38.\r\n\r\n\u00c1lvarez, A., Cacabelos, R., Moessler, H., Doppler, E. Cerebrolysin in moderate to moderately severe Alzheimer disease (AD): Subgroup analysis of a randomized, double-blind, placebo-controlled trial (RCT). 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 39.\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V., Seoane, S., Cacabelos, R. Alpha-2-macroglobulin polymorphisms in probable Alzheimer disease. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 58.\r\n\r\nFern\u00e1ndez-Novoa, L., Corzo, L., Zas, R., Seoane, S., Cacabelos, R. ACE InDel polymorphism, serum ACE activity and plasma beta-amyloid in dementia. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 59.\r\n\r\nLombardi, V., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Cellular immune changes in peripheral blood of Alzheimer disease patients. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 85.\r\n\r\nLombardi, V., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Activation of immune cells in peripheral blood of Alzheimer disease patients. 8th International Montreal\/Springfield Symposium on Advances in Alzheimer Therapy. Montreal, April 14-17, 2004; pp. 86.\r\n\r\nCacabelos, R. The pathogenic role of histamine in Alzheimer disease. 33rd Annual Meeting European Histamine Research Society. D\u00fcsseldorf\/K\u00f6ln, April 28-May 2, 2004; pp. 30.\r\n\r\n\u00c1lvarez, X.A., Cacabelos, R., Vargas, M., Aleixandre, M., Linares, C., Granizo, E., Moessler, H. Dose-response effects of cerebrolysin in Alzheimer\u2019s disease patients: A randomized, double-blind, placebo-controlled trial. XXIV CINP Congress, June 2004. Int. J. Neuropsychopharmacol., 7(Suppl.1): S383 (2004).\r\n\r\nLombardi, V., \u00c1lvarez, X.A., Echeverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Alterations in percentages of lymphocyte subpopulations in peripheral blood of Alzheimer\u2019s disease patients. XXIV CINP Congress, June 2004. Int. J. Neuropsychopharmacol., 7(Suppl.1\u00a0: S383 (2004).\r\n\r\n\u00c1lvarez, X.A., Laredo, M., Cruceiro, V., Sampedro, C., Cacabelos, R., Illescas, E., Vargas, M., Moessler, H. Frequency and severity of neuropsychiatric symptoms in Alzheimer\u2019s disease and mild cognitive impairment: influence of the APOE genotype. XXIV CINP Congress, June 2004. Int. J. Neuropsychopharmacol., 7(Suppl.1): S384 (2004).\r\n\r\nCacabelos, R. Gen\u00e9tica y envejecimiento. Congreso Internacional. El Reto del Envejecimiento 1979-2004. 25 A\u00f1os de Atenci\u00f3n Gerontol\u00f3gico en M\u00e9xico. M\u00e9xico DF, 16-18 Junio, 2004.\r\n\r\nCacabelos, R. Farmacogen\u00f3mica y envejecimiento. Galisenior. 4\u00ba Sal\u00f3n Gallego de Nuestros Mayores. I Foro Europeo sobre Envejecimiento. Orense, 21-23 Octubre, 2004.\r\n\r\nFern\u00e1ndez-Novoa, L., Seoane, S., Lombardi, V., Cacabelos, R. The influence of genotype on blood lipid parameters in Alzheimer\u2019s disease and control subjects. 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 25 (2005).\r\n\r\n\u00c1lvarez, X.A., Cacabelos, R., Moessler, H. Cerebrolysin: Efficacy and safety in moderate to moderately severe Alzheimer\u2019s disease- A subgroup analysis of a randomized, double-blind, placebo-controlled trial. 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 46 (2005).\r\n\r\nCacabelos, R. Functional genomics and pharmacogenomics of Alzheimer\u2019s disease. 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 56 (2005).\r\n\r\n\u00c1lvarez, X.A., Corzo, L., Zas, R., Sampedro, C., Cacabelos, R. Serum TNF-alpha in Alzheimer\u2019s disease: Increased levels and negative correlations with IGF-1. 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 120 (2005).\r\n \r\n\u00c1lvarez, X.A., Sampedro, C., Cruceiro, V., Corzo, L., Cacabelos, R., Aleixandre, M., Vargas, M., Linares, C., Granizo, E., Moessler, H. Double-blind, placebo-controlled study of three doses of cerebrolysin in mild to moderate Alzheimer\u2019s disease. 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 136 (2005).\r\n\r\nLombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Alterations of immune functions and lymphocyte apoptosis in patients with Alzheimer\u2019s disease (AD). 7th International Conference AD\/PD 2005. Alzheimer\u2019s and Parkinson\u2019s diseases: Insights, Progress and Perspectives. Sorrento, March 9-13, pp. 170 (2005).\r\n\r\nCacabelos, R. Pharmacogenomics studies in Alzheimer\u2019s disease: Genotype-related therapeutic response. Joint Meeting of the 27th Annual Meeting of the Japanese Society of Biological Psychiatry (JSBP) and the 35th Annual Meeting of the Japanese Society of Neuropsychopharmacology (JSNP). Osaka, July 6-8, pp. 15, 2005.\r\n\r\nCacabelos, R. Pharmacogenetics and pharmacogenomics of CNS disorders. Joint Meeting of the 27th Annual Meeting of the Japanese Society of Biological Psychiatry (JSBP) and the 35th Annual Meeting of the Japanese Society of Neuropsychopharmacology (JSNP). Osaka, July 6-8, pp. 93, 2005.\r\n\r\n\u00c1lvarez, A., Laredo, M., Couceiro, V., Sampedro, C., Cacabelos, R., Illescas, E., Vargas, M. Neuropsychiatric symptoms in Alzheimer\u2019s disease versus mild cognitive impairment. XIII World Congress of Psychiatry, Cairo, Egypt, 10-15 Sept. PO1.P259 (2005).\r\n\r\n\u00c1lvarez, A., Cacabelos, R., Laredo, M., Varela, M., Sampedro, C., Aleixandre, M., Illescas, E., Linares, C., Granizo, E., Moessler, H. Cerebrolysin in Alzheimer\u2019s disease: a double-blind, placebo-controlled study. XIII World Congress of Psychiatry, Cairo, Egypt, 10-15 Sept. OR22.6 (2005).\r\n\r\n\r\n\u00c1lvarez, A., Laredo, M., Couceiro, V., Sampedro, C., Cacabelos, R., Illescas, E., Aleixandre, M. Neuropsychiatric symptoms in vascular dementia: Comparison with AD and mild cognitive impairment. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Cruceiro, V., Garc\u00eda, C., Vargas, M., Cuesta, I., Cacabelos, R., Moessler, H. Cognitive improvement and EEG activation by cerebrolysin in vascular dementia: an exploratory study. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).\r\n\r\nCacabelos, R., Fern\u00e1ndez-Novoa, L., Lombardi, V., Tellado, I., Nebril, L., Casas, A., Alcaraz, M., Pichel, V. Structural genomics studies in vascular dementia (VD) and Alzheimer disease (AD): Differential genomic patterns and genetic variation. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).\r\n\r\nFern\u00e1ndez-Novoa, L., Seoane, S., Corzo, L., Lombardi, V.R.M., Cacabelos, R. Genetic risk factors and lipid parameters in dementia. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).\r\n\r\nCorzo, L., Fern\u00e1ndez-Novoa, L., Rodr\u00edguez, S., Cacabelos, R. Decreased serum nitric oxide levels in vascular dementia. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).\r\n\r\nLombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Peripheral increases in IL-6, lymphocyte apoptosis and immune activation in patients with dementia. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).\r\n\r\nPichel, V., Tellado, I., Nebril, L., Casas, A., Alcaraz, M., Varela, M., Cacabelos, R. Disease-specific differences in brain hemodynamics in patients with vascular dementia, Alzheimer\u2019s disease and Parkinson\u2019s disease. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).\r\n\r\nTellado, I., Pichel, V., Nebril, L., Casas, A., Alcaraz, M., Varela, M., Cacabelos, R. Influence of blood pressure on brain hemodynamics and bioelectrical activity spectral power in vascular dementia, Alzheimer\u2019s disease and Parkinson\u2019s disease. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).\r\n\r\nTellado, I., Pichel, V., Cacabelos, R. Brain bioelectrical activity spectral power in vascular dementia, Alzheimer\u2019s disease and Parkinson\u2019s disease. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).\r\n\r\nPichel, V., Tellado, I., Nebril, L., Casas, A., Alcaraz, M., Varela, M., Cacabelos, R. Age-related brain hemodynamics in vascular dementia, Alzheimer\u2019s disease and Parkinson\u2019s disease. Fourth International Congress on Vascular Dementia, Porto, Portugal, 20-23 Oct (2005).\r\n\r\nCacabelos, R. Pharmacogenetic aspects of therapy with cholinesterase inhibitors. 9th International Geneva\/Springfield Symposium on Advances in Alzheimer Therapy. 19-22 April, Geneva, Neurobiol. Aging, 27 (S1): S4 (2006).\r\n\r\n\u00c1lvarez, A., Laredo, M., Varela, M., Cacabelos, R., Sampedro, C., Aleixandre, M., Linares, C., Moessler, H. Double-blind, placebo-controlled study of three different dosages of cerebrolysin in patients with mild to moderate Alzheimer\u2019s disease. Alzheimer\u2019s Association 10th International Conference on Alzheimer\u2019s Disease and Related Disorders. Madrid, 15-20 July. Alzheimer\u2019s & Dementia, 2(Suppl.1):S364 (2006).\r\n\r\n\u00c1lvarez, A., Corzo, L., Couceiro, V., Sampedro, C., Cacabelos, R. Cerebrolysin reduces the increased levels of serum tumor necrosis factor-alpha in Alzheimer\u2019s disease. Alzheimer\u2019s Association 10th International Conference on Alzheimer\u2019s Disease and Related Disorders. Madrid, 15-20 July. Alzheimer\u2019s & Dementia, 2(Suppl.1): S370 (2006).\r\n\r\nCacabelos, R. Introducci\u00f3n a la Medicina Gen\u00f3mica en Neurociencias. I Conferencia Anual EuroEspes, Coru\u00f1a, 15 Dic (2006).\r\n\r\nCacabelos, R. Pharmacogenomics and therapeutic prospects in dementia. Pharmainnovation. Pharmaceutical Innovation. Bonn, 11-12 June (2007).\r\n\r\n\u00c1lvarez, X.A., Linares, C., Aleixandre, M., Cacabelos, R., Hitzl, M. Tratamiento neurotr\u00f3fico en la enfermedad de Alzheimer: Mecanismos moleculares y estudios cl\u00ednicos. XII Congreso Panamericano de Neurolog\u00eda. Santo Domingo, 7-11 Oct. pp. 16 (2007).\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Garc\u00eda-Fantini, M., Linares, C., Aleixandre, M., Cacabelos, R., Hitzl, M. Interacci\u00f3n funcional entre TNF-alfa e IGF-I en la enfermedad de Alzheimer: Implicaciones patog\u00e9nicas y terap\u00e9uticas. XII Congreso Panamericano de Neurolog\u00eda. Santo Domingo, 7-11 Oct. pp. 51-52 (2007).\r\n\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R., Moessler, H. Interaction between TNF-alpha and IGF-I in Alzheimer disease: Pathogenic and therapeutic implications. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1): 334 (2007).\r\n\r\nCacabelos, R. Influence of pharmacogenetic factors on Alzheimer\u2019s disease. Therapeutics. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1): 4 (2007).\r\n\r\nFern\u00e1ndez-Novoa, L., Llovo, R., Seoane, S., Bello, A., Rey, P., Corzo, L., Cacabelos, R. Cholesteryl ester transfer protein (CETP) gene and cholesterol metabolism in dementia. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1): 119 (2007).\r\n\r\nIsaza, C., Henao, J., Llovo, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Similar pharmacogenetic patterns of CYP2C19 in Spanish and Colombian populations. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1): 138 (2007).\r\n\r\nIsaza, C., Henao, J., Llovo, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. CYP2D6 in the Spanish population with dementia. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1): 138 (2007).\r\n\r\nCorzo, L., Fern\u00e1ndez-Novoa, L., Rodr\u00edguez, S., Cacabelos, R. Vascular risk factors and endothelial NOS3 polymorphism variants in Alzheimer\u2019s disease. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1):143-144 (2007).\r\n\r\nLombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Lymphocyte subset markers and cytokine production in peripheral blood of patients with AD. 8th International Conference AD\/PD, Salzburg, Austria, March 14-18. Neurodegenerative Dis., 4(Suppl.1):229 (2007).\r\n\r\nCacabelos, R. La medicina gen\u00f3mica en las enfermedades degenerativas y el c\u00e1ncer. II Congreso Internacional sobre Tratamientos Complementarios y Alternativos en C\u00e1ncer. Madrid, 26 Mayo (2007).\r\n\r\nCacabelos, R. Pharmacogenetics and therapeutic optimization in dementia. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):8-9 (2007).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Cacabelos, R., Moessler, H. Functional interaction of serum tumor necrosis factor-alpha and insulin growth factor-I in Alzheimer\u2019s disease. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):300 (2007).\r\n\r\nLombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. IL-1beta, IL-6 and TNF-alpha inflammatory cytokines and lymphocyte subset markers in patients with Alzheimer\u2019s disease (AD). Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):302-303 (2007).\r\n\r\nLombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Inflammatory and immune responses in patients with Alzheimer\u2019s disease (AD). Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):303 (2007).\r\n\r\nLombardi, V.R.M., Fern\u00e1ndez-Novoa, L., Llovo, R., Seoane, S., Corzo, L., Cacabelos, R. Cholesteryl ester transfer protein (CETP) gene and cholesterol in Alzheimer\u2019s disease. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):303-304 (2007).\r\n\r\nLombardi, V.R.M., Llovo, R., Fern\u00e1ndez-Novoa, L., Seoane, S., Henao, J., Cacabelos, R. CYP2D6 in the Spanish population with dementia. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):304 (2007).\r\n\r\nLombardi, V.R.M., Llovo, R., Fern\u00e1ndez-Novoa, L., Seoane, S., Henao, J., Cacabelos, R. Similar pharmacogenetic patterns of CYP2C19 in Spanish and Colombian populations. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):304-305 (2007).\r\n\r\nLombardi, V.R.M., Llovo, R., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Genetic polymorphisms of cytochromes P450: CYP2D6, CYP2C19 and CYP2C9 in Spanish population. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):305 (2007).\r\n\r\nCorzo, L., Rodr\u00edguez, S., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Alzheimer\u2019s disease-associated peripheral markers are interrelated to lipid metabolism. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):307 (2007).\r\n\r\nCorzo, L., Rodr\u00edguez, S., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Endothelial NOS3 polymorphism influence on peripheral vascular markers in Alzheimer\u2019s disease. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):307-308 (2007).\r\n\r\nTellado, I., Fraile, C., Cacabelos, R. Brain optical topography in Alzheimer\u2019s disease and vascular dementia. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):308 (2007).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Cruceiro, V., Cacabelos, R., Aleixandre, M., Moessler, H. Neuropsychiatric symptoms and ApoE-4 in patients with cognitive deterioration: Impact on functioning. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):335-336 (2007).\r\n\r\nTellado, I., Fraile, C., Cacabelos, R. Impact of ApoE genotype on brain function as assessed by optical topography. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):363 (2007).\r\n\r\nTellado, I., Fraile, C., Cacabelos, R. ACE genotype-related changes in brain optical topography. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):363-364 (2007).\r\n\r\nCorzo, L., Vallejo, A.I., Antelo, A.M., Lombardi, V., Cacabelos, R. E-JUR-94013; a nutraceutical compound with immunomodulatory effects in the elderly. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):416 (2007).\r\n\r\nTellado, I., Fraile, C., Cacabelos, R. Brain optical topography patterns in stroke, vascular encephalopathy and migraine. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):426 (2007).\r\n\r\nLombardi, V.R.M., Etcheverr\u00eda, J., D\u00edaz, J., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Silver Congress of the International Psychogeriatric Association. Osaka, 14-18 Oct. International Psychogeriatrics, 19(Suppl.1):Add. 5 (2007).\r\n\r\nCacabelos, R. Dementia in Europe: Present and future challenges. Aiming for the Communities Living Together with Dementia \u2013 In Japan and the World. Aging and Dementia \u2013 the States in Japan and Abroad. Osaka International Convention Center, Osaka, 14 Oct. (2007).\r\n\r\n\u00c1lvarez X.A., Sampedro, C., Corzo, L., Cacabelos, R. Alterations of serum TNF-alpha and IGF-I levels in vascular dementia. Fifth International Congress on Vascular Dementia. Budapest, Hungary, Nov 8-11 (2007).\r\n\r\nCacabelos, R. Medicina Gen\u00f3mica. Congreso Internacional de Medicina Biol\u00f3gica. Medicina Funcional de Vanguardia. Universidad Aut\u00f3noma de Guadalajara, Guadalajara, M\u00e9xico; 30 Nov., 2007. \r\n\r\nCacabelos, R. Farmacogen\u00f3mica aplicada a las neurociencias cl\u00ednicas. II Conferencia Anual EuroEspes, Coru\u00f1a, Dic. 15 (2007).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Couceiro, V., Cacabelos, R., Doppler, E., Hitzl, M., Moessler, H. Cerebrolysin in moderate to moderately severe Alzheimer disease: Efficacy and safety analysis in a subgroup of a double-blind, placebo-controlled trial. Alzheimer\u2019s Association International Conference on Alzheimer\u2019s Disease (ICAD). Chicago, July 26-31 (2008).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Cacabelos, R., Linares, C., Granizo, E., Aleixandre, M., Moessler, H. Cerebrolysin reduces TNF-alpha and soluble TNF receptor-1 levels in the serum of Alzheimer disease patients. Alzheimer\u2019s Association International Conference on Alzheimer\u2019s Disease (ICAD). Chicago, July 26-31 (2008).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Cacabelos, R., Linares, C., Granizo, E., Aleixandre, M., Garc\u00eda-Fantini, M. Hyperactivity of peripheral TNF-alpha system in Alzheimer\u2019s disease: Interaction with serum IGF-1. Alzheimer\u2019s Association International Conference on Alzheimer\u2019s Disease (ICAD). Chicago, July 26-31 (2008).\r\n\r\nCacabelos, R. Manejo pr\u00e1ctico de la farmacogen\u00e9tica en ni\u00f1os y adultos. Jornadas M\u00e9dicas, Hospital Espa\u00f1ol, M\u00e9xico DF, Febrero 16 (2008).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Cacabelos, R., Linares, C., Granizo, E., Aleixandre, M., Garc\u00eda-Fantini, M. Hyperactivity of peripheral TNF-alpha system in Alzheimer\u2019s disease: Interaction with serum IGF-I. Alzheimer\u2019s Association International Conference on Alzheimer\u2019s Disease. July 26-31. Alzheimer\u2019s & Dementia, 4(Suppl.2):T137 (2008).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Cruceiro, V., Cacabelos, R., Aleixandre, M., Doppler, E., Moessler, H. Cerebrolysin in moderate to moderately severe Alzheimer\u2019s disease: a subgroup analysis of efficacy and safety data. 12th Congress of the European Federation of Neurological Societies, Madrid, August 23-26. Eur. J. Neurol., 15(Suppl.3):24 (2008).\r\n\r\nCacabelos, R. Pharmacogenomics in CNS Disorders. 51st Annual Meeting of the Japanese Society of Neurochemistry, Sept. 11. Bull. Jap Soc Neurochem., 47: 210 (2008).\r\n\r\nCacabelos, R. Genotype-related phenotypic expression of biomarkers in dementia: Implications for pharmacogenomics. World Federation of Societies of Biological Psychiatry. 2nd WFSBP Asia-Pacific Congress and 30th Annual Meeting of JSBP. 11-13 Sept. The World Journal of Biological Psychiatry, Vol. 9(Suppl.1):82 (2008).\r\n\r\nCacabelos, R. Farmacogen\u00f3mica en las enfermedades neurol\u00f3gicas. XXXII Reuni\u00f3n Anual Academia Mexicana de Neurolog\u00eda. Puerto Vallarta, 25 Oct. \u2013 1 Nov. (2008).\r\n\r\nCacabelos, R. Genomic medicine and pharmacogenomics of neuropsychiatric disorders. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:26-29 (2008). \r\n\r\nHarguindey S, D\u00edaz de Otazu, R., Arlueca, J., Catal\u00e1n, J., Arranz, J.L., Orive, G., Reshkin, S.J., Cacabelos, R. Human neurodegenerative diseases (hndds) and cancer: an integral approach to the etiopathogenesis and treatment of hndds within the frame of the trophic factor withdrawal syndrome (TFWS). III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:66 (2008).\r\n\r\nMart\u00ednez, E., Chac\u00f3n, R., Etcheverr\u00eda, I., Cacabelos, R., Lombardi, V.R.M. Cytotoxicity effects induced by FR-91 on human tumor cell lines. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:68 (2008).\r\n\r\nMart\u00ednez, E., Chacon, R., Cacabelos, R., Etcheverr\u00eda, I., Lombardi, V.R.M. Effects of FR-91 on immune cells from healthy individuals and patients with non-Hodgkin lymphoma. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:68 (2008).\r\n\r\nLombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Caspase 3 activity in PBMCs from Alzheimer\u2019s disease patients: when and why do cells die? III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:69 (2008).\r\n\r\nDes, J., P\u00e9rez, R., Alcaraz, M., Nebril, L., Fern\u00e1ndez-Novoa, L., Cacabelos, R. ACE-related blood pressure values in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:69-70 (2008).\r\n\r\nDes, J., P\u00e9rez, R., Alcaraz, M., Nebril, L., Fern\u00e1ndez-Novoa, L., Cacabelos, R. ACE-related brain hemodynamic parameters in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:70 (2008).\r\n\r\nP\u00e9rez, R., Des, J., Fraile, C., Fern\u00e1ndez-Novoa, L., Corzo, L., Cacabelos, R. FOS-related blood biochemical parameters and brain hemodynamics in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:70 (2008).\r\n\r\nP\u00e9rez, R., Des, J., Fraile, C., Fern\u00e1ndez-Novoa, L., Corzo, L., Cacabelos, R. APOE-related blood biochemical parameters and brain hemodynamics in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:71 (2008).\r\n\r\nAguilar Aldrete, M.E., Moran Moguel, M.C., Sandoval-Ram\u00edrez, L., Rosales-G\u00f3mez, R.C., Guti\u00e9rrez-Rubio, S.A., Rodr\u00edguez-Vega, M.C., Parra Bernal, M.C., Cacabelos, R. Comparative study of APOE polymorphisms in the Mexican population: Alzheimer\u2019s disease vs. Indians and mestizos. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:74 (2008).\r\n\r\n\u00c1lvarez, A., Cacabelos, R., Mandler, M., Mattner, F. Mimovax: A novel approach for a safe vaccine for Alzheimer\u2019s disease. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:75 (2008).\r\n\r\nFraile, C., Mart\u00ednez, R., Cacabelos-P\u00e9rez, N., Corzo, L., Fern\u00e1ndez-Novoa, L., Cacabelos-P\u00e9rez, R., Cacabelos, R. Presenilin-related biochemical and brain hemodynamic parameters in patients with Alzheimer\u2019s disease. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:75-76 (2008).\r\n\r\nFraile, C., Llovo, R., Mart\u00ednez, R., Cacabelos-P\u00e9rez, N., Corzo, L., Fern\u00e1ndez-Novoa, L., Cacabelos-P\u00e9rez, R., Cacabelos, R. CYP2D6-related biochemical and brain hemodynamic parameters in patients with Alzheimer\u2019s disease. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:76 (2008).\r\n\r\nMart\u00ednez, R., Cacabelos-P\u00e9rez, N., Cacabelos-P\u00e9rez, R., Cacabelos, R. CYP genes and drug metabolism: major substrates for antidepressants, neuroleptics and benzodiazepines. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:76-77 (2008).\r\n\r\nLlovo, R., Tudoli, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Genetic polymorphisms of Cytochrome P450: CYP2D6, CYP2C19, CYP2C9 and CYP3A5 in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:77 (2008).\r\n\r\nLlovo, R., Fern\u00e1ndez-Novoa, L., Seoane, S., Tudoli, I., Cacabelos, R. Pharmacogenetic patterns of CYP2C9 and VKORC1 in the Spanish population. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:78 (2008).\r\n\r\nCorzo, L., Rodr\u00edguez, S., Cacabelos, R. Important role of novel vascular risk factors to decrease vascular risk in patients with dementia. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:78-79 (2008).\r\n\r\nCarril, J.C., Tudoli, I., Cacabelos, R. IL-6 and IL-6R gene polymorphisms and risk of stroke and neurodegeneration. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:79 (2008).\r\n\r\nCarril, J.C., Llovo, R., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Logistic regression as a useful tool to explain genetic risk of stroke. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:79 (2008).\r\n\r\nFern\u00e1ndez-Novoa, L., Seoane, S., Llovo, R., Tudoli, I., Cacabelos, R. Vascular genetic risk factors in Alzheimer\u2019s disease. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:80 (2008).\r\n\r\nTellado, I. Cacabelos, R. Effect of ACE genotype on brain bioelectrical activity. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:80 (2008).\r\n\r\nFern\u00e1ndez-Novoa, L., Seoane, S., Llovo, R., Tudoli, I., Corzo, L., Cacabelos, R. Polygenic risk factors related to neurodegeneration in Alzheimer\u2019s disease: calculation of a genetic predisposition store (GPS). III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:90-81 (2008).\r\n\r\nLombardi, V.R.M., Etcheverr\u00eda, I., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Chronic activation of PBMCS in Alzheimer\u2019s disease patients. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:81 (2008).\r\n\r\nCorzo, L., Rodr\u00edguez, S., Fern\u00e1ndez-Novoa, L., Laredo, M., Cruceiro, V., Cacabelos, R. Association of novel vascular risk factors and cognitive function in dementia. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:82 (2008).\r\n\r\nTellado, I., Cacabelos, R. Impact of APOE genotype on brain bioelectrical activity. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:82-83 (2008). \r\n\r\nTellado, I., Fraile, C., Cacabelos, R. Influence of APOE genotype on brain function as assessed by Optical Topography. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:83 (2008).\r\n\r\nLaredo, M., Couceiro, V., \u00c1lvarez, A., Sampedro, C., Cacabelos, R. Neuropsychiatric symptoms and APOE-4 in cognitively impaired patients. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:84 (2008).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Corzo, L., Cacabelos, R. Immuno-trophic regulation in Alzheimer\u2019s disease: TNF-ALPHA\/IGF-I interactions. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:84 (2008).\r\n\r\nMart\u00ednez, R., Alejo, R., Lombardi, V., Fern\u00e1ndez-Novoa, L., Corzo, L., Alcaraz, M., Nebril, L., Casas, A., Fraile, C., Vallejo, A., Cacabelos, R. Nutraceutical properties of E-SAR-94010 (LipoEsar\u00ae): APOE-related nutrigenomic profile. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:85 (2008).\r\n\r\nMart\u00ednez, R., Fraile, C., Cacabelos-P\u00e9rez, N., Cacabelos-P\u00e9rez, R., Fern\u00e1ndez-Novoa, L., Corzo, L., Lombardi, V., Tellado, I., P\u00e9rez, R., Laredo, M., Cruceiro, V., \u00c1lvarez, A., Des, J., Cacabelos, R. APOE-related phenotypic profile in Alzheimer\u2019s disease and vascular dementia. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:85-89 (2008).\r\n\r\nLlovo, R., Fern\u00e1ndez-Novoa, L., Tudoli, I., Vallejo, A., Cacabelos, R. Genetic polymorphisms of several genes associated with key metabolic pathways in obesity. III EuroEspes Annual Conference, 1st Meeting World Association of Genomic Medicine, Coru\u00f1a, Dec. 12-13 (2008). Gen-T\/The EuroEspes Journal (International Edition) 2:89-90 (2008).\r\n\r\n\u00c1lvarez, A., Cacabelos, R., Aleixandre, M., Linares, C., Granizo, E., Doppler, E., Moessler, H. Double-blind clinical trial with cerebrolysin, donepezil and a combination therapy in mild to moderate Alzheimer\u2019s disease. Second Joint Congress of GCNN and SSNN. Vienna, 1-3 March (2009). \r\n\r\nCacabelos, R. Pharmacogenomic protocols in CNS disorders and dementia. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 18 (2009).\r\n\r\nCorzo, L., Rodr\u00edguez, S., Fern\u00e1ndez-Novoa, L., Laredo, M., Cruceiro, V., Cacabelos, R. Influence of vascular risk factors on cognitive status. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 105 (2009).\r\n\r\nFern\u00e1ndez-Novoa, L., Seoane, S., Llovo, R., Tudoli, I., Corzo, L., Cacabelos, R. Polygenic risk factors in Alzheimer disease: Calculation of a genetic predisposition store (GPS). 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 147 (2009).\r\n\r\nCarril, J.C., Fern\u00e1ndez-Novoa, L., Llovo, R., Cacabelos, R. Logistic regression as a useful tool to explain genetic risk of stroke. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 154 (2009).\r\n\r\nFern\u00e1ndez-Novoa, L., Llovo Mari\u00f1o, R., Tudoli, S., Seoane, S., Cacabelos, R. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 155 (2009).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Corzo, L., Cacabelos, R., Aleixandre, M., Vargas, M., Linares, C., Granizo, E. Modulatory effects of cerebrolysin on TNF-alpha and IGF.I in Alzheimer\u2019s disease. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 200 (2009).\r\n\r\nFern\u00e1ndez-Novoa, L., Etcheverr\u00eda, I., Seoane, S., Cacabelos, R., Lombardi, V. Immune studies in peripheral blood of patients with Alzheimer\u2019s disease. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 206 (2009).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Cacabelos, R. Inflammatory biomarkers are associated with low IGF-I levels and disability in Alzheimer\u2019s disease. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 208 (2009).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Cruceiro, V., Cacabelos, R., Aleixandre, M., Vargas, M., Linares, C., Granizo, E., Doppler, E., Novak, P., Moessler, H. Cerebrolysin, donepezil and a combination therapy in Alzheimer\u2019s disease: Results of a double-blind clinical trial. 9th International Conference AD\/PD 2009, Prague, March 11-15, p. 231 (2009).\r\n\r\nCacabelos, R. C\u00e1ncer y enfermedades neurodegenerativas (Ende) como opuestos metab\u00f3licos \u00e1cido-b\u00e1sicos. Enfoque gen\u00e9tico y factores de crecimiento en etiopatogenia y tratamiento. International Symposium. Transporte de protones y su inhibici\u00f3n (ITP) en la etiopatogenia, diagn\u00f3stico y tratamiento del c\u00e1ncer. Fundaci\u00f3n Ram\u00f3n Areces, Madrid, 28-29 Abril (2009). \r\n\r\nTakeda, M., Shibata, N., Kim, D.K., Cacabelos, R. Pharmacogenomics and nutrigenomics in CNS disorders of the elderly. IPA 2009 International Meeting. Brain Aging and Quality of Life, Rio de Janeiro, Brazil, 4-7 May, (2009).\r\n\r\nCacabelos, R. Genomic mechanisms of neurodegeneration: implications for pharmacogenomics and nutrigenomics. The Second Annual Iberian Congress on Anti-Aging Medicine and Biomedical Technologies. Vilamoura-Algarve, Portugal, June 4-6, (2009).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Cacabelos, R., Novak, P., Moessler, H. Opposite effects of cerebrolysin on serum TNF-alpha and IGF-I levels in Alzheimer\u2019s disease. Alzheimer\u2019s Association 2009 International Conference on Alzheimer\u2019s Disease (ICAD). Vienna, 11-16 July (2009).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Cacabelos, R. Overexpression of inflammation markers in Alzheimer\u2019s disease: Clinical correlates. Alzheimer\u2019s Association 2009 International Conference on Alzheimer\u2019s Disease (ICAD). Vienna, 11-16 July (2009).\r\n\r\nCacabelos, R. Biomarkers and pharmacogenomics. Alzheimer\u2019s Association 2009 International Conference on Alzheimer\u2019s Disease (ICAD). Vienna, 11-16 July (2009).\r\n\r\nCacabelos, R. Conferencia Inaugural. III Congreso Internacional sobre Tratamientos Complementarios y Alternativos en C\u00e1ncer. World Association for Cancer Research, Madrid, 31 Oct-1 Nov. (2009).\r\n\r\n\u00c1lvarez, X.A., Sampedro, C., Cacabelos, R. Clinical relevance of peripheral inflammatory biomarkers in Alzheimer\u2019s disease and vascular dementia. Sixth International Congress on Vascular Dementia, Barcelona, 19-22 Nov. (2009).\r\n\r\nCacabelos, R. Medicina personalizada en el abordaje cl\u00ednico de la demencia: Farmacogen\u00f3mica de la enfermedad de Alzheimer. IV Conferencia Anual EuroEspes. Avances en Medicina Gen\u00f3mica, Coru\u00f1a, Dic. 19 (2009). \r\n\r\nCacabelos, R. Nutrigenomic component of marine biotechnology products for human Health. 239th American Chemical Society National Meeting & Exposition. San Francisco, USA, March 21-25, pp. TECH-58 (2010).\r\n\r\nCacabelos, R. Farmacogen\u00e9tica de la enfermedad de Alzheimer. XXXIII Congreso Nacional de Farmacolog\u00eda para Estudiantes. Universidad Aut\u00f3noma de Madrid, Madrid, 4-5 Mayo, 2010.\r\n\r\nCacabelos, R., Avramopoulos, Baskys, A., Cai, Y. Genetic testing in neuropsychiatry: APOE and beyond. 10th Annual Meeting of the International College of Geriatric Psychoneuropharmacology. The Divani Palace Acropolis Hotel, Athens, 15-18 September, 2010.\r\n\r\nCacabelos, R. Genomics and pharmacogenomics of psychotic disorders. VII Congress of the Polish Society of Psychogeriatrics. Wroclaw, 2-3 December, 2010.\r\n\r\n\u00c1lvarez, A., Cacabelos, R., Couceiro, V., Aleixandre, M., Doppler, E., Novak, P., Moessler, H. Effects of Cerebrolysin on neuropsychiatric symptoms in Alzheimer\u2019s disease: results of a randomized, placebo-controlled trial. 14th Congress of the European Federation of Neurological Societies. Eur. J. Neurol., 17(Suppl. 3), 72 (2010).\r\n\r\n\u00c1lvarez, A., Sampedro, C., Couceiro, V., Cacabelos, R., Garc\u00eda-Fantini, M., Aleixandre, M., Linares, C., Granizo, E. Apathy influences functional impairment in mild to moderate Alzheimer\u2019s disease. 14th Congress of the European Federation of Neurological Societies. Eur. J. Neurol., 17(Suppl. 3), 86 (2010).\r\n\r\nCacabelos, R. Nutrigen\u00f3mica y farmacogen\u00f3mica: de la teor\u00eda a la pr\u00e1ctica. VII Congreso Internacional de Nutrici\u00f3n, Alimentaci\u00f3n y Diet\u00e9tica. XV Jornadas Nacionales de Nutrici\u00f3n Pr\u00e1ctica. Sociedad Espa\u00f1ola de Diet\u00e9tica y Ciencias de la Alimentaci\u00f3n. Universidad Complutense, Madrid, 30-31 Marzo- 1 Abril, 2011. Revista de Nutrici\u00f3n Pr\u00e1ctica 15:9-10 (2011).\r\n\r\nCacabelos, R. Functional genomics and pharmacogenomics of CNS disorders. 10th World Congress of Biological Psychiatry, pp. 100, Prague, 29 May \u2013 2 June, 2011.\r\n\r\nFern\u00e1ndez-Novoa, L., Cacabelos, R. APOE and CYP2D6 in CNS disorders. European Human Genetics Conference 2011, Amsterdam, 28-31 May, 2011. Eur J Hum Genet 19 (Suppl. 2):284 (2011).\r\n\r\nFern\u00e1ndez-Novoa, L., Carril, J., Seoane, S., Cacabelos, R. Characterization of the genomic risk profile in cerebrovascular diseases. European Human Genetics Conference 2011, Amsterdam, 28-31 May, 2011. Eur J Hum Genet 19 (Suppl. 2):290 (2011).\r\n\r\nFern\u00e1ndez-Novoa, L., Seoane, S., Carril, J., Garc\u00eda-Ag\u00fandez, J.A., Cacabelos, R. LRRK2 mutations in sporadic and familial Parkinson disease. European Human Genetics Conference 2011, Amsterdam, 28-31 May, 2011. Eur J Hum Genet 19 (Suppl. 2):300 (2011).\r\n\r\nCacabelos, R. Pharmacogenomics of schizophrenia and lipid metabolism alterations in CNS disorders. 3rd World Congress of Asian Psychiatry 2011. Melbourne, 31 July \u2013 4 August, 2011. Asian Journal of Psychiatry 4(Suppl. 1): 11 (2011).\r\n\r\nCacabelos, R., S\u00e1nchez, J. Introduction to the World Guide of Pharmacogenomics. VI Conferencia Annual EuroEspes, Gen-T 8:34-35 (2011).\r\n\r\nCarril, J.C., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Caracterizaci\u00f3n del perfil gen\u00e9tico de riesgo cerebrovascular. VI Conferencia Annual EuroEspes, Gen-T 8:88 (2011).\r\n\r\nCarril, J.C., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Citoquinas proinflamatorias polim\u00f3rficas como marcadores gen\u00e9ticos de aterosclerosis. VI Conferencia Annual EuroEspes, Gen-T 8:88-89 (2011).\r\n\r\nCanuet, L., Tellado, I., Couceiro, V., Fraile, C., Cacabelos, R. Perfil fenot\u00edpico EEG de conectividad funcional y actividad oscilatoria en la enfermedad de Alzheimer. VI Conferencia Annual EuroEspes, Gen-T 8:89-90 (2011).\r\n\r\nCanuet, L., Tellado, I., Corzo, L., Fraile, C., Cacabelos, R. Relaci\u00f3n del genotipo APOE y niveles s\u00e9ricos de LDL-colesterol con la actividad bioel\u00e9ctrica cerebral en pacientes con enfermedad de Alzheimer. VI Conferencia Annual EuroEspes, Gen-T 8:90 (2011).\r\n\r\nCorzo, L., Lombardi, V., Alejo, R., Rodr\u00edguez, S., Cacabelos, R. Bioproperties and clinical effects of Juritrofin (DefenVid\u00ae). VI Conferencia Annual EuroEspes, Gen-T 8:91-92 (2011).\r\n\r\nCorzo, L., Rodr\u00edguez, S., Alejo, R., Cacabelos, R. Biological properties of Mineraxin. VI Conferencia Annual EuroEspes, Gen-T 8:92 (2011).\r\n\r\nFern\u00e1ndez-Novoa, L., Corzo, L., Seoane, S., Carril, J.C., Cacabelos, R. A genomic approach to histamine function. VI Conferencia Annual EuroEspes, Gen-T 8:93-94 (2011).\r\n\r\nFern\u00e1ndez-Novoa, L., Cacabelos, R. Histamine function in brain disorders. VI Conferencia Annual EuroEspes, Gen-T 8:94 (2011).\r\n\r\nLombardi, V.R.M., Carrera, I., Etcheverr\u00eda, I., Mart\u00ednez, E., Chac\u00f3n, R., Cacabelos, R. Prevenci\u00f3n de colitis experimental cr\u00f3nica inducida por dextr\u00e1n sulfato s\u00f3dico (DSS) en ratones tratados con FR-91. VI Conferencia Annual EuroEspes, Gen-T 8:94-95 (2011).\r\n\r\nLombardi, V.R.M., Alejo, R., Etcheverr\u00eda, I., Pablos, A., Cacabelos, R. Testaje experimental de las propiedades de bioproductos en preparados de Alimentos Naturales, S.A. VI Conferencia Annual EuroEspes, Gen-T 8:95 (2011).\r\n\r\nTellado, I., Canuet, L., Couceiro, V., Fraile, C., Cacabelos, R. Cambios en la actividad bioel\u00e9ctrica cerebral durante el envejecimiento y el deterioro cognitivo. VI Conferencia Annual EuroEspes, Gen-T 8:95-96 (2011).\r\n\r\nTellado, I., Canuet, L., Fraile, C., Cacabelos, R. Influencia del alelo APOE-4 sobre la funci\u00f3n cerebral en ancianos sanos. VI Conferencia Annual EuroEspes, Gen-T 8:96 (2011).\r\n\r\nCacabelos, R. \u00bfSe puede prevenir la enfermedad de Alzheimer? IX Jornadas de Actualizaci\u00f3n en Vacunas. Vacunas para una salud global. Sal\u00f3n de Actos Casa de las Mariposas, Almer\u00eda, 1-2 Octubre (2012).\r\n\r\nCacabelos, R. Farmacogen\u00f3mica y vacuna anti-Alzheimer. XXXI Lecci\u00f3n Memorial. Visi\u00f3n cr\u00edtica de la prevenci\u00f3n cardiovascular: focaliz\u00e1ndose en los factores determinantes del envejecimiento saludable. Fundaci\u00f3n Fern\u00e1ndez-Cruz. Auditorio del Hospital Cl\u00ednico San Carlos, Madrid, 26 Nov (2012).\r\n\r\nCacabelos, R. Genomics and Pharmacogenomics of neurodegeneration. Longeva. Congresso Internazionale ECM. Medicina preventiva, predittiva e rigenerativa. Fiera Milano Rho, Mil\u00e1n, 30 Nov- 1 Dic (2012).\r\n\r\nAliev, G., Bragin, V., Cacabelos, R. Implication of integrative treatment for real-life geriatric patients with depression, dementia and multiple chronic diseases: A 60-month follow-up of a naturistic study. 5th Clinical Trial son Alzheimer\u2019s disease (CTAD) Conference. Montecarlo, France, Oct 29-31 (2012). J Nutrition Health Ageing 16:840-841 (2012).\r\n\r\nCorzo, L., Rodr\u00edguez, S., Cacabelos. Novel vascular risk factor evaluation can improve the prediction and prevention of vascular risk in dementia. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-07-009 (2013).\r\n\r\nCorzo, L., Rodr\u00edguez, S., Fern\u00e1ndez-Novoa, L., Couceiro, V., Cacabelos, R. Vascular risk factors in dementia: Influence of APOE, MTHFR, NOS3, PSEN1 and ACE polymorphisms and association with cognitive function scores. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-07-015 (2013).\r\n\r\nCacabelos, R. Influence of pleiotropic genes in CNS Pharmacogenomics. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, S-048-004 (2013).\r\n\r\nFern\u00e1ndez-Novoa, L., Seoane, S., Carril, J.C., Ag\u00fandez, J.A., Cacabelos, R. G2019S mutation in sporadic and familial Parkinson\u2019s disease. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-10-004 (2013).\r\n\r\nFern\u00e1ndez-Novoa, L., Lombardi, V., Etcheverr\u00eda, I., Cacabelos, R. The effects of acute and chronic psychological stress on immune function in a rat model. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-12-016 (2013).\r\n\r\nCarril, J.C., Corzo, L., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Characterization of the genomic risk profile in cerebrovascular diseases. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-13-022 (2013).\r\n\r\nCarril, J.C., Torrellas, C., Fraile, C., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Error rate in antidepressant Drug prescription: the importance of personalized medicine. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-18-005 (2013).\r\n\r\nCarril, J.C., Torrellas, C., Fraile, C., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Pharmacogenetics as a predictive tool to reduce errors in the administration of anxiolytics, hypnotics and sedatives. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-18-006 (2013).\r\n\r\nCarril, J.C., Fraile, C., Torrellas, C., Couceiro, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R. The importance of pharmacogenetics in the treatment of psychotic disorders. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-18-009 (2013).\r\n\r\nCarril, J.C., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos, R. Characterization of CYP3A polymorphisms in the Spanish population. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-18-015 (2013).\r\n\r\nTellado, I., Corzo, L., Canuet, L., Couceiro, V., Fraile, C., Cacabelos, R. Age-related changes in brain networks: A bioelectrical source localization and functional connectivity study in resting state. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-20-003 (2013).\r\n\r\nCanuet, L., Tellado, I., Couceiro, V., Fraile, C., Fern\u00e1ndez-Novoa, L., Ishii, R., Takeda, M., Cacabelos, R. Phenotypic profile of brain functional connectivity and oscillatory activity in Alzheimer\u2019s disease. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-21-010 (2013).\r\n\r\nCanuet, L., Tellado, I., Corzo, L., Fern\u00e1ndez-Novoa, L., Fraile, C., Torrellas, C., Ishii, R., Takeda, M., Cacabelos, R. Association of APOE genotype and LDL-cholesterol levels with brain electrical activity in Alzheimer\u2019s disease. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-21-011 (2013).\r\n\r\nCanuet, L., Ishii, R., Pascual-Marqui,M., Iwase, M., Takeda, M., Cacabelos, R., del Pozo, F., Maestu, F. Resting-state EEG source localization and functional connectivity in schizophrenia-like psychosis of epilepsy and Alzheimer\u2019s disease using eLORETA. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-84-002 (2013).\r\n\r\nCacabelos, R. Pharmacogenomics of lipid metabolism dysfunction in dementia. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, S-100-004 (2013).\r\n\r\nFern\u00e1ndez-Novoa, L., Tellado, I., Canuet, L., Couceiro, V., Fraile, C., Cacabelos, R. Impact of APOE-4 allele on brain activity in aging. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-26-004 (2013).\r\n\r\nFern\u00e1ndez-Novoa, L., Carril, J.C., Seoane, S., Cacabelos, R. An association study between histamine and polymorphisms in immune system genes in mental disorders. WFSBP Congress, 11th World Congress of Biological Psychiatry, 23-27 June, Kyoto, P-28-025 (2013).\r\n\r\nCacabelos, R. APOE-TOMM40 and CYP2D6 in the Pharmacogenomics of dementia. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.\r\n\r\nCarril, J.C., Cacabelos, R. Characterization of CYP3A polymorphisms in the Spanish population. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.\r\n\r\nCarril, J.C., Corzo, L., Fern\u00e1ndez-Novoa, L., Seoane, S., Cacabelos. Characterization of the genomic risk profile in cerebrovascular diseases. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.\r\n\r\nTorrellas, C., Fraile, C., Carril, J.C., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Error rate in antidepressant Drug prescription: the importance of personalized medicine. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.\r\n\r\nTorrellas, C., Pi\u00f1eiro, S., Villanueva, M.J., Solveira, C., Fraile, C., Carril, J.C., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Hypertension management: benefits of pharmacogenetics. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.\r\n\r\nTorrellas, C., Fraile, C., Carril, J.C., Fern\u00e1ndez-Novoa, L., Cacabelos, R. Pharmacogenetics as a predictive tool to reduce errors in the administration of anxiolytics, hypnotics and sedatives. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.\r\n\r\nCarril, J.C., Fraile, C., Torrellas, C., Couceiro, V., Fern\u00e1ndez-Novoa, L., Cacabelos, R. The importance of pharmacogenetics in the treatment of psychotic disorders. European Society of Pharmacogenomics and Theranostics ESPT-2013. Second Conference. Pharmacogenomics: From Cell to Clinic. Sept 26-28, Lisbon, Portugal.\r\nL\u00f3pez-Mu\u00f1oz F, Salado-Font S, P\u00e9rez-Nieto MA, Cacabelos R. Evolution ofCamilo Jos\u00e9 Cela University\u2019s international publications in health sciences: Bibliometric analysis. XI Foro Internacional sobre Evaluaci\u00f3n de la Calidad de la Investigaci\u00f3n y la Educaci\u00f3n Superior (FECIES). Bilbao, 8-10 July (2014).\r\n\r\nCacabelos R. Nutrigenomics and nutraceutical intervention as a preventive strategy in lipid metabolism and age-related disorders. AMEC DACH 2014. Aesthetic & Anti-Aging Medicine European Congress. Berlin 20-21 June, 2014.\r\n\r\n\r\nCacabelos R, Goldgaber D, Vostrov A, Matsuki H, Torrellas C, Carril JC. TOMM40 poly T variants modify the pharmacogenetic response to conventional treatments in Alzheimer\u2019s Disease. 7th Santorini Conference Biologie Prospective. Systems Medicine, Personalized Health and Therapy. ESPT. Sept 25-27, 2014.\r\n\r\nCarril JC, Cacabelos R. Atherogenic biomarkers in vascular dementia: the role of inflammation in neurodegeneration. 7th Santorini Conference Biologie Prospective. Systems Medicine, Personalized Health and Therapy. ESPT. Sept 25-27, 2014.\r\n\r\nCorzo L, Carril JC, Rodr\u00edguez S, Couceiro V, Cacabelos R. Vascular risk factors in dementia: Influence of APOE, MTHFR, NOS3, PSEN1 and ACE polymorphysms and association with cognitive function scores. 7th Santorini Conference Biologie Prospective. Systems Medicine, Personalized Health and Therapy. ESPT. Sept 25-27, 2014.\r\n\r\nCorzo L, Rodr\u00edguez S, Carril JC, Cacabelos. Relationships between genetic vascular risk polymorphysms and serum vascular biomarkers. 7th Santorini Conference Biologie Prospective. Systems Medicine, Personalized Health and Therapy. ESPT. Sept 25-27, 2014.\r\n\r\nTorrellas C, Carril JC, Cacabelos R. Pharmacogenetics of antidepressant drugs: Optimizing prescription. 7th Santorini Conference Biologie Prospective. Systems Medicine, Personalized Health and Therapy. ESPT. Sept 25-27, 2014.\r\n\r\nCacabelos R. Pharmacogenetics of psychotropic drugs: The UCJC pharmacogenetic card for personalized treatment. WPA Regional Congress, Osaka International Convention Center, Osaka, Japan, 4-6 June, 2015.","_et_gb_content_width":"","footnotes":""},"yoast_head":"\nCongress - Rc<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rcacabelos.eliteksolutions.xyz\/en\/congress\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Congress - Rc\" \/>\n<meta property=\"og:description\" content=\"Congresos Takagi, T., Tanizawa, O., Sugita, N., Mori, M., Otsuki, Y., Yamaji, K., Kurachi, K., Cacabelos, R., Nishimura, T., Senba, E., Tohyama, M., Shiotani, Y. Study of immunoreactive- oxytocin in human placenta and its localization. Proc. 56th Jap. Cong. Endocrinol., Osaka, Folia Endocrinol. 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